diazepam has been researched along with Memory Disorders in 43 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Memory Disorders: Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the present study, the effects of intraamygdalar administrations of melatonin (1 and 100μg/kg), saline and diazepam on the anxiety-like behavior and spatial memory performance in pinealectomized and sham-pinealectomized Wistar rats were investigated." | 7.77 | The effects of the intraamygdalar melatonin injections on the anxiety like behavior and the spatial memory performance in male Wistar rats. ( Coşkun, H; Gündüz, B; Karakaş, A; Kaya, A; Kücük, A, 2011) |
| "In the present study, the effects of intraamygdalar administrations of melatonin (1 and 100μg/kg), saline and diazepam on the anxiety-like behavior and spatial memory performance in pinealectomized and sham-pinealectomized Wistar rats were investigated." | 3.77 | The effects of the intraamygdalar melatonin injections on the anxiety like behavior and the spatial memory performance in male Wistar rats. ( Coşkun, H; Gündüz, B; Karakaş, A; Kaya, A; Kücük, A, 2011) |
| "Humanin (HN) is an endogenous 24-residue peptide." | 1.46 | Humanin ameliorates diazepam-induced memory deficit in mice. ( Maruyama, T; Murakami, M; Nagahama, M; Niikura, T, 2017) |
| "CSL also reversed successfully the memory deficits induced by scopolamine (0." | 1.37 | Reversal of memory deficits by Coriandrum sativum leaves in mice. ( Abdul Majeed, AB; Mani, V; Parle, M; Ramasamy, K, 2011) |
| "Epilepsy affects 0." | 1.37 | Bone marrow mononuclear cells reduce seizure frequency and improve cognitive outcome in chronic epileptic rats. ( Cammarota, M; DaCosta, JC; Greggio, S; Machado, DC; Marinowic, DR; Venturin, GT; Zanirati, G, 2011) |
| "Dementia is one of the age related mental problems and a characteristic symptom of various neurodegenerative disorders including Alzheimer's disease." | 1.33 | Evaluation of nootropic potential of Ocimum sanctum Linn. in mice. ( Joshi, H; Parle, M, 2006) |
| "Diazepam-treated animals differed from controls in erring on trials in which they failed to investigate both test objects, failed to investigate the test object for a long enough period of time, and displaced the test object on the preferred side of the apparatus." | 1.28 | Behavioral analysis of diazepam-induced memory deficits: evidence for sedation-like effects. ( Beck, CH; Kalynchuk, LE, 1992) |
| " The results have implications for evaluating the safety of the long-term use of BZ medications." | 1.27 | Chronic use of benzodiazepines and psychomotor and cognitive test performance. ( Geller, AM; Lucki, I; Rickels, K, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (13.95) | 18.7374 |
| 1990's | 9 (20.93) | 18.2507 |
| 2000's | 10 (23.26) | 29.6817 |
| 2010's | 16 (37.21) | 24.3611 |
| 2020's | 2 (4.65) | 2.80 |
| Authors | Studies |
|---|---|
| Guerrini, G | 1 |
| Ciciani, G | 1 |
| Cambi, G | 1 |
| Bruni, F | 1 |
| Selleri, S | 1 |
| Besnard, F | 1 |
| Montali, M | 1 |
| Martini, C | 1 |
| Ghelardini, C | 2 |
| Galeotti, N | 1 |
| Costanzo, A | 1 |
| Sang, Z | 2 |
| Pan, W | 1 |
| Wang, K | 2 |
| Ma, Q | 1 |
| Yu, L | 1 |
| Yang, Y | 1 |
| Bai, P | 2 |
| Leng, C | 1 |
| Xu, Q | 1 |
| Li, X | 1 |
| Tan, Z | 1 |
| Liu, W | 1 |
| Zhang, P | 1 |
| Shi, J | 1 |
| Cheng, X | 1 |
| Zhang, Q | 1 |
| Zheng, C | 1 |
| Cheng, Y | 1 |
| Yang, J | 1 |
| Lu, X | 1 |
| Di Capua, A | 1 |
| Reale, A | 1 |
| Paolino, M | 1 |
| Chemi, G | 1 |
| Brogi, S | 1 |
| Cappelli, A | 1 |
| Giorgi, G | 1 |
| Grande, F | 1 |
| Di Cesare Mannelli, L | 1 |
| Matucci, R | 1 |
| Garofalo, A | 1 |
| Anzini, M | 1 |
| Victorino, DB | 1 |
| Pinheiro, DJLL | 1 |
| Scott-McKean, JJ | 1 |
| Barker, S | 1 |
| Stasko, MR | 1 |
| Faber, J | 1 |
| Scorza, CA | 1 |
| Costa, ACS | 1 |
| Dominguez, G | 1 |
| Henkous, N | 1 |
| Pierard, C | 1 |
| Belzung, C | 2 |
| Mons, N | 1 |
| Beracochea, D | 1 |
| Kurlawala, Z | 1 |
| Roberts, JA | 1 |
| McMillan, JD | 1 |
| Friedland, RP | 1 |
| Sasaki-Hamada, S | 1 |
| Sacai, H | 1 |
| Sugiyama, A | 1 |
| Iijima, T | 1 |
| Saitoh, A | 1 |
| Inagaki, M | 1 |
| Yamada, M | 1 |
| Oka, J | 1 |
| de Rezende, VB | 1 |
| Rosa, DV | 1 |
| Comim, CM | 1 |
| Magno, LA | 1 |
| Rodrigues, AL | 1 |
| Vidigal, P | 1 |
| Jeromin, A | 1 |
| Quevedo, J | 1 |
| Romano-Silva, MA | 1 |
| Deshpande, LS | 1 |
| Phillips, K | 1 |
| Huang, B | 1 |
| DeLorenzo, RJ | 1 |
| Orzelska, J | 2 |
| Talarek, S | 2 |
| Listos, J | 2 |
| Fidecka, S | 2 |
| López-Granero, C | 1 |
| Ruiz-Muñoz, AM | 1 |
| Nieto-Escámez, FA | 1 |
| Colomina, MT | 1 |
| Aschner, M | 1 |
| Sánchez-Santed, F | 1 |
| Silva, AF | 1 |
| Sousa, DS | 1 |
| Medeiros, AM | 1 |
| Macêdo, PT | 1 |
| Leão, AH | 1 |
| Ribeiro, AM | 1 |
| Izídio, GS | 1 |
| Silva, RH | 1 |
| Del Rio, D | 1 |
| Morales, L | 1 |
| Ruiz-Gayo, M | 1 |
| Del Olmo, N | 1 |
| Murakami, M | 1 |
| Nagahama, M | 1 |
| Maruyama, T | 1 |
| Niikura, T | 1 |
| Kim, DH | 1 |
| Kim, S | 1 |
| Jeon, SJ | 1 |
| Son, KH | 1 |
| Lee, S | 1 |
| Yoon, BH | 1 |
| Cheong, JH | 1 |
| Ko, KH | 1 |
| Ryu, JH | 1 |
| Riedel, G | 1 |
| Kang, SH | 1 |
| Choi, DY | 1 |
| Platt, B | 1 |
| Mani, V | 1 |
| Parle, M | 2 |
| Ramasamy, K | 1 |
| Abdul Majeed, AB | 1 |
| Karakaş, A | 1 |
| Coşkun, H | 1 |
| Kaya, A | 1 |
| Kücük, A | 1 |
| Gündüz, B | 1 |
| Venturin, GT | 1 |
| Greggio, S | 1 |
| Marinowic, DR | 1 |
| Zanirati, G | 1 |
| Cammarota, M | 1 |
| Machado, DC | 1 |
| DaCosta, JC | 1 |
| Hlinák, Z | 1 |
| Krejcí, I | 1 |
| El Hage, W | 1 |
| Peronny, S | 1 |
| Griebel, G | 1 |
| de Jong, LA | 1 |
| Verwey, B | 1 |
| Essink, G | 1 |
| Muntendam, A | 1 |
| Zitman, FG | 1 |
| Ensing, K | 1 |
| Rich, JB | 1 |
| Svoboda, E | 1 |
| Brown, GG | 1 |
| Joshi, H | 1 |
| Ragnehed, M | 1 |
| Håkansson, I | 1 |
| Nilsson, M | 1 |
| Lundberg, P | 1 |
| Söderfeldt, B | 1 |
| Engström, M | 1 |
| Brooker, AE | 1 |
| Wiens, AN | 1 |
| Wiens, DA | 1 |
| Ishihara, Y | 1 |
| Hirai, K | 1 |
| Miyamoto, M | 1 |
| Goto, G | 1 |
| Tata, PR | 1 |
| Rollings, J | 1 |
| Collins, M | 1 |
| Pickering, A | 1 |
| Jacobson, RR | 1 |
| Paróczai, M | 1 |
| Kiss, B | 1 |
| Kárpáti, E | 1 |
| Shaji, AV | 1 |
| Kulkarni, SK | 1 |
| Wagemans, J | 1 |
| Notebaert, W | 1 |
| Boucart, M | 1 |
| Gorissen, ME | 1 |
| Eling, PA | 1 |
| Leri, F | 1 |
| Franklin, KB | 1 |
| Baglietto, MG | 1 |
| Battaglia, FM | 1 |
| Nobili, L | 1 |
| Tortorelli, S | 1 |
| De Negri, E | 1 |
| Calevo, MG | 1 |
| Veneselli, E | 1 |
| De Negri, M | 1 |
| Kalynchuk, LE | 1 |
| Beck, CH | 1 |
| Goodwin, FK | 1 |
| Pomara, N | 1 |
| Deptula, D | 1 |
| Medel, M | 1 |
| Block, RI | 1 |
| Greenblatt, DJ | 1 |
| Lucki, I | 1 |
| Rickels, K | 1 |
| Geller, AM | 1 |
| Green, LM | 1 |
| De Buck, R | 2 |
| Boon, H | 1 |
| Pelc, I | 1 |
7 trials available for diazepam and Memory Disorders
| Article | Year |
|---|---|
Diazepam-induced prospective memory impairment and its relation to retrospective memory, attention, and arousal.
Topics: Adult; Arousal; Attention; Diazepam; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; M | 2006 |
Influence of diazepam on clinically designed FMRI.
Topics: Adult; Anticonvulsants; Brain; Decision Making; Diazepam; Double-Blind Method; Female; Functional La | 2007 |
Lorazepam but not diazepam impairs identification of pictures on the basis of specific contour fragments.
Topics: Adult; Diazepam; Double-Blind Method; Female; Humans; Lorazepam; Male; Memory; Memory Disorders; Psy | 1998 |
Dual task performance after diazepam intake: can resource depletion explain the benzodiazepine-induced amnesia?
Topics: Adult; Affect; Aged; Amnesia; Analysis of Variance; Anti-Anxiety Agents; Attention; Diazepam; Double | 1998 |
Effects of diazepam on recall memory: relationship to aging, dose, and duration of treatment.
Topics: Adult; Aged; Aging; Diazepam; Female; Humans; Male; Memory Disorders; Middle Aged; Time Factors | 1989 |
[Comparative study of the anxiolytic efficacy of lorazepam (WY 4036) and diazepam (Valium)].
Topics: Adolescent; Adult; Aged; Anxiety; Asthenia; Benzazepines; Clinical Trials as Topic; Diazepam; Evalua | 1972 |
Clinical experience with lorazepam in the treatment of neurotic patients.
Topics: Adult; Anxiety Disorders; Asthenia; Benzodiazepinones; Chlorobenzenes; Clinical Trials as Topic; Dia | 1973 |
36 other studies available for diazepam and Memory Disorders
| Article | Year |
|---|---|
Novel 3-iodo-8-ethoxypyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide as promising lead for design of alpha5-inverse agonist useful tools for therapy of mnemonic damage.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Ataxia; Diazepam; Drug Design; GABA Agonists; gamma-Aminobuty | 2007 |
Design, synthesis and evaluation of novel ferulic acid-O-alkylamine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blood-Brain Barrier; Butyrylcholine | 2017 |
Development of chalcone-O-alkylamine derivatives as multifunctional agents against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Biological Tr | 2019 |
Design, synthesis and biological evaluation of 7-substituted 4-phenyl-6H-imidazo[1,5-a]thieno[3,2-f] [1,4]diazepines as safe anxiolytic agents.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Binding Sites; Drug Design; Locomoti | 2020 |
Atypical electrophysiological and behavioral responses to diazepam in a leading mouse model of Down syndrome.
Topics: Animals; Diazepam; Disease Models, Animal; Down Syndrome; Electrophysiological Phenomena; Female; Lo | 2021 |
Repeated diazepam administration reversed working memory impairments and glucocorticoid alterations in the prefrontal cortex after short but not long alcohol-withdrawal periods.
Topics: Alcoholism; Animals; Anxiety; Central Nervous System Depressants; Cyclic AMP Response Element-Bindin | 2018 |
Diazepam Toxicity Presenting as a Dementia Disorder.
Topics: Aged; Alzheimer Disease; Benzodiazepines; Diagnosis, Differential; Diazepam; Humans; Male; Memory Di | 2018 |
Riluzole does not affect hippocampal synaptic plasticity and spatial memory, which are impaired by diazepam in rats.
Topics: Amnesia; Animals; Anti-Anxiety Agents; Diazepam; Hippocampus; Male; Memory; Memory Disorders; Neuron | 2013 |
NCS-1 deficiency causes anxiety and depressive-like behavior with impaired non-aversive memory in mice.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety Disorders; Avoidance Learnin | 2014 |
Chronic behavioral and cognitive deficits in a rat survival model of paraoxon toxicity.
Topics: Anhedonia; Animals; Anxiety; Atropine; Behavior, Animal; Cognition Disorders; Depression; Diazepam; | 2014 |
Divergent effects of L-arginine-NO pathway modulators on diazepam and flunitrazepam responses in NOR task performance.
Topics: Animals; Arginine; Diazepam; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flunitrazepam; GAB | 2015 |
Chronic dietary chlorpyrifos causes long-term spatial memory impairment and thigmotaxic behavior.
Topics: Aging; Animals; Anti-Anxiety Agents; Chlorpyrifos; Cholinesterase Inhibitors; Cues; Diazepam; Dizoci | 2016 |
Sex and estrous cycle influence diazepam effects on anxiety and memory: Possible role of progesterone.
Topics: 5-alpha Reductase Inhibitors; Animals; Anxiety; Diazepam; Dose-Response Relationship, Drug; Estrous | 2016 |
Effect of high-fat diets on mood and learning performance in adolescent mice.
Topics: Affect; Animals; Anti-Anxiety Agents; Depressive Disorder; Diazepam; Diet, High-Fat; Exploratory Beh | 2016 |
Humanin ameliorates diazepam-induced memory deficit in mice.
Topics: Alzheimer Disease; Animals; Anticonvulsants; Cognition; Diazepam; Disease Models, Animal; Intracellu | 2017 |
The effects of acute and repeated oroxylin A treatments on Abeta(25-35)-induced memory impairment in mice.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Behavior, Animal; CD11b Antigen; Diazepam; Dos | 2008 |
Scopolamine-induced deficits in social memory in mice: reversal by donepezil.
Topics: Animals; Anti-Anxiety Agents; Cholinesterase Inhibitors; Diazepam; Donepezil; Dose-Response Relation | 2009 |
Reversal of memory deficits by Coriandrum sativum leaves in mice.
Topics: Aging; Animals; Anticholesteremic Agents; Avoidance Learning; Brain; Cholesterol; Cholinesterase Inh | 2011 |
The effects of the intraamygdalar melatonin injections on the anxiety like behavior and the spatial memory performance in male Wistar rats.
Topics: Amygdala; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Diazepam; Disease Models, Ani | 2011 |
Bone marrow mononuclear cells reduce seizure frequency and improve cognitive outcome in chronic epileptic rats.
Topics: Animals; Bone Marrow Cells; Cell Transplantation; Chronic Disease; Cognition Disorders; Diazepam; Di | 2011 |
Effects of NOS inhibitors on the benzodiazepines-induced memory impairment of mice in the modified elevated plus-maze task.
Topics: Animals; Benzodiazepines; Diazepam; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flunitrazep | 2013 |
Oxiracetam prevented the scopolamine but not the diazepam induced memory deficits in mice.
Topics: Animals; Anxiety; Diazepam; Female; GABA Modulators; Maze Learning; Memory Disorders; Mice; Muscarin | 2002 |
Impaired memory following predatory stress in mice is improved by fluoxetine.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Diazepam; Exploratory Behavi | 2004 |
Determination of the benzodiazepine plasma concentrations in suicidal patients using a radioreceptor assay.
Topics: Anti-Anxiety Agents; Benzodiazepines; Chromatography, High Pressure Liquid; Cross Reactions; Diazepa | 2004 |
Evaluation of nootropic potential of Ocimum sanctum Linn. in mice.
Topics: Alzheimer Disease; Amnesia; Animals; Dementia; Diazepam; Dose-Response Relationship, Drug; Humans; M | 2006 |
Impaired brain functions due to diazepam and meprobamate abuse in a 53-year-old-male.
Topics: Cognition Disorders; Diazepam; Humans; Male; Memory Disorders; Meprobamate; Middle Aged; MMPI; Motor | 1984 |
Central cholinergic agents. 6. Synthesis and evaluation of 3-[1-(phenylmethyl)-4-piperidinyl]-1-(2,3,4,5-tetrahydro-1H-1-benzazepi n-8-yl)-1-propanones and their analogs as central selective acetylcholinesterase inhibitors.
Topics: Animals; Behavior, Animal; Benzazepines; Cholinesterase Inhibitors; Diazepam; In Vitro Techniques; M | 1994 |
Lack of cognitive recovery following withdrawal from long-term benzodiazepine use.
Topics: Adult; Benzodiazepines; Cognition Disorders; Diazepam; Female; Humans; Male; Memory Disorders; Middl | 1994 |
Effect of RGH-2716 on learning and memory deficits of young and aged rats in water-labyrinth.
Topics: Aging; Amnesia, Retrograde; Animals; Diazepam; Learning Disabilities; Male; Maze Learning; Memory; M | 1998 |
Evidence of GABAergic modulation in melatonin-induced short-term memory deficits and food consumption.
Topics: Animals; Antioxidants; Diazepam; Eating; Female; Flumazenil; GABA Modulators; Latency Period, Psycho | 1998 |
Learning impairments caused by lesions to the pedunculopontine tegmental nucleus: an artifact of anxiety?
Topics: Animals; Anti-Anxiety Agents; Anxiety; Artifacts; Diazepam; Learning Disabilities; Male; Maze Learni | 1998 |
Neuropsychological disorders related to interictal epileptic discharges during sleep in benign epilepsy of childhood with centrotemporal or Rolandic spikes.
Topics: Anticonvulsants; Attention; Case-Control Studies; Child; Cognition Disorders; Diazepam; Electroencep | 2001 |
Behavioral analysis of diazepam-induced memory deficits: evidence for sedation-like effects.
Topics: Animals; Behavior, Animal; Diazepam; Discrimination Learning; Hypnotics and Sedatives; Male; Memory | 1992 |
From the Alcohol, Drug Abuse, and Mental Health Administration.
Topics: Brain; Caffeine; Cocaine; Diazepam; Drug Synergism; Ethanol; Fetus; Humans; Memory; Memory Disorders | 1991 |
Chronic use of benzodiazepines and psychomotor and cognitive test performance.
Topics: Adult; Affect; Aged; Alprazolam; Anti-Anxiety Agents; Benzodiazepines; Clorazepate Dipotassium; Cogn | 1986 |
The effect of diazepam on patients' memory.
Topics: Diazepam; Humans; Memory Disorders | 1985 |