diazepam has been researched along with Melanoma in 8 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The DNS II acetone fraction of Delphinium nordhagenii has exhibited the anticonvulsant actions by preventing the seizures against PTZ- and picrotoxin-induced seizure as well as 100% seizure protection in MES test." | 3.76 | Anticonvulsant activity of DNS II fraction in the acute seizure models. ( Ahmad, M; Raza, ML; Shaheen, F; Simjee, SU; Zeeshan, M, 2010) |
| "1) activity and melanin synthesis, are induced by diazepam in B16/C3 mouse melanoma cells." | 3.66 | Benzodiazepines have high-affinity binding sites and induce melanogenesis in B16/C3 melanoma cells. ( Engelhardt, DL; Hsu, KC; Laskin, JD; Matthew, E; Weinstein, IB; Zimmerman, EA, 1981) |
| "This report is an example of tumor metastasis to the temporomandibular joint and its effect on pain, restriction of jaw movement, and the subsequent inability of the patient to function normally." | 1.25 | Myofascial pain dysfunction syndrome involving tumor metastasis. Case report. ( Butler, JH, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Raza, ML | 1 |
| Zeeshan, M | 1 |
| Ahmad, M | 1 |
| Shaheen, F | 1 |
| Simjee, SU | 1 |
| Adam, S | 1 |
| Vessey, M | 1 |
| Matthew, E | 1 |
| Laskin, JD | 1 |
| Zimmerman, EA | 1 |
| Weinstein, IB | 1 |
| Hsu, KC | 1 |
| Engelhardt, DL | 1 |
| Sporny, S | 1 |
| Ortega, F | 1 |
| Carreras, JL | 1 |
| Maldonado, A | 1 |
| Pérez-Castejón, MJ | 1 |
| Montz, R | 1 |
| Gorospe, E | 1 |
| Ruiz, JA | 1 |
| Nieto, C | 1 |
| Niles, LP | 1 |
| Wang, J | 1 |
| Butler, JH | 1 |
| Solowey, WE | 1 |
| Pestka, S | 1 |
| Spector, S | 1 |
| Fryer, RI | 1 |
| Fisher, PB | 1 |
1 review available for diazepam and Melanoma
| Article | Year |
|---|---|
[Diazepam and neoplasms].
Topics: Animals; Breast Neoplasms; Cocarcinogenesis; Diazepam; Female; Humans; Leukemia L1210; Liver Neoplas | 1984 |
7 other studies available for diazepam and Melanoma
| Article | Year |
|---|---|
Anticonvulsant activity of DNS II fraction in the acute seizure models.
Topics: Acetone; Animals; Anticonvulsants; Delphinium; Diazepam; Epilepsy; Male; Melanoma; Mice; Mice, Inbre | 2010 |
Diazepam and malignant melanoma.
Topics: Adolescent; Adult; Diazepam; Female; Humans; Melanoma; Middle Aged; Skin Neoplasms | 1981 |
Benzodiazepines have high-affinity binding sites and induce melanogenesis in B16/C3 melanoma cells.
Topics: Benzodiazepines; Cells, Cultured; Diazepam; Fluorescent Antibody Technique; Kinetics; Melanins; Mela | 1981 |
[Muscle uptake of 18FDG in positron emission tomography].
Topics: Antineoplastic Agents; Anxiety; Breast Neoplasms; Diazepam; Female; Fluorine Radioisotopes; Fluorode | 1998 |
Diazepam inhibits forskolin-stimulated adenylyl cyclase activity in human tumour cells.
Topics: Adenylyl Cyclase Inhibitors; Anti-Anxiety Agents; Breast Neoplasms; Cell Membrane; Colforsin; Diazep | 1999 |
Myofascial pain dysfunction syndrome involving tumor metastasis. Case report.
Topics: Breast Neoplasms; Diagnosis, Differential; Diazepam; Facial Muscles; Female; Humans; Mandibular Neop | 1975 |
Peripheral-acting benzodiazepines inhibit the growth of human melanoma cells and potentiate the antiproliferative activity of recombinant human interferons.
Topics: Antineoplastic Agents; Benzodiazepines; Cell Division; Diazepam; Drug Synergism; Humans; Interferon | 1990 |