diazepam has been researched along with Malaria, Falciparum in 5 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Falciparum malaria is the most common cause of convulsions in children admitted to hospital in malaria endemic areas." | 2.42 | Management of seizures in children with falciparum malaria. ( Newton, CR; Ogutu, BR, 2004) |
| "Diazepam is used to terminate convulsions but its pharmacokinetics and pharmacodynamics have not been studied in this group." | 1.31 | Pharmacokinetics and anticonvulsant effects of diazepam in children with severe falciparum malaria and convulsions. ( Crawley, J; Edwards, G; Kokwaro, GO; Marsh, K; Muchohi, SN; Newton, CR; Ogutu, BR; Otieno, GO, 2002) |
| "Treatment with diazepam, haloperidol and thioridazine achieved relief of the severe symptoms after 4 days." | 1.29 | [Mefloquine and sulfadoxine/pyrimethamine overdose in malaria tropica]. ( Bergqvist, Y; Breyer, S; Burgmann, H; Feistauer, S; Feucht, M; Graninger, W; Hellgren, U; Uhl, F; Winkler, S, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ikumi, ML | 1 |
| Muchohi, SN | 2 |
| Ohuma, EO | 1 |
| Kokwaro, GO | 2 |
| Newton, CR | 3 |
| Bouyer, G | 1 |
| Cueff, A | 1 |
| Egée, S | 1 |
| Kmiecik, J | 1 |
| Maksimova, Y | 1 |
| Glogowska, E | 1 |
| Gallagher, PG | 1 |
| Thomas, SL | 1 |
| Ogutu, BR | 2 |
| Burgmann, H | 1 |
| Winkler, S | 1 |
| Uhl, F | 1 |
| Feucht, M | 1 |
| Hellgren, U | 1 |
| Bergqvist, Y | 1 |
| Feistauer, S | 1 |
| Breyer, S | 1 |
| Graninger, W | 1 |
| Crawley, J | 1 |
| Otieno, GO | 1 |
| Edwards, G | 1 |
| Marsh, K | 1 |
1 review available for diazepam and Malaria, Falciparum
| Article | Year |
|---|---|
Management of seizures in children with falciparum malaria.
Topics: Anticonvulsants; Child; Diazepam; Emergency Treatment; Humans; Malaria, Cerebral; Malaria, Falciparu | 2004 |
4 other studies available for diazepam and Malaria, Falciparum
| Article | Year |
|---|---|
Response to diazepam in children with malaria-induced seizures.
Topics: Anticonvulsants; Child; Child, Preschool; Diazepam; Epilepsy; Female; Histidine; Humans; Infant; Inj | 2008 |
Erythrocyte peripheral type benzodiazepine receptor/voltage-dependent anion channels are upregulated by Plasmodium falciparum.
Topics: Antimalarials; Benzodiazepinones; Diazepam; Erythrocytes; Humans; In Vitro Techniques; Ion Channel G | 2011 |
[Mefloquine and sulfadoxine/pyrimethamine overdose in malaria tropica].
Topics: Adult; Diazepam; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combi | 1993 |
Pharmacokinetics and anticonvulsant effects of diazepam in children with severe falciparum malaria and convulsions.
Topics: Administration, Rectal; Anticonvulsants; Area Under Curve; Child, Preschool; Diazepam; Female; Human | 2002 |