diazepam has been researched along with Irritable Bowel Syndrome in 2 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Irritable Bowel Syndrome: A disorder with chronic or recurrent colonic symptoms without a clearcut etiology. This condition is characterized by chronic or recurrent ABDOMINAL PAIN, bloating, MUCUS in FECES, and an erratic disturbance of DEFECATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The primary efficacy endpoint showed a tendency towards a statistically significant benefit for octatropine plus diazepam over placebo among patients with a baseline abdominal pain and discomfort score of > or = 3 (3 vs." | 9.14 | Octatropine methyl bromide and diazepam combination (Valpinax) in patients with irritable bowel syndrome: a multicentre, randomized, placebo-controlled trial. ( Attili, A; Ciacci, C; Iaquinto, G; Magni, E; Maurano, A; Pace, F; Porro, GB; Savarino, V, 2010) |
| "Curcumin is a biologically active phytochemical presents in turmeric and has pharmacological actions that benefit patients with depression and anxiety." | 5.42 | The effect of curcumin on the brain-gut axis in rat model of irritable bowel syndrome: involvement of 5-HT-dependent signaling. ( Li, J; Pan, J; Wang, R; Wu, S; Xie, X; Xu, Y; Yu, X; Yu, Y; Zheng, L, 2015) |
| "The primary efficacy endpoint showed a tendency towards a statistically significant benefit for octatropine plus diazepam over placebo among patients with a baseline abdominal pain and discomfort score of > or = 3 (3 vs." | 5.14 | Octatropine methyl bromide and diazepam combination (Valpinax) in patients with irritable bowel syndrome: a multicentre, randomized, placebo-controlled trial. ( Attili, A; Ciacci, C; Iaquinto, G; Magni, E; Maurano, A; Pace, F; Porro, GB; Savarino, V, 2010) |
| "Curcumin is a biologically active phytochemical presents in turmeric and has pharmacological actions that benefit patients with depression and anxiety." | 1.42 | The effect of curcumin on the brain-gut axis in rat model of irritable bowel syndrome: involvement of 5-HT-dependent signaling. ( Li, J; Pan, J; Wang, R; Wu, S; Xie, X; Xu, Y; Yu, X; Yu, Y; Zheng, L, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, Y | 1 |
| Wu, S | 1 |
| Li, J | 1 |
| Wang, R | 1 |
| Xie, X | 1 |
| Yu, X | 1 |
| Pan, J | 1 |
| Xu, Y | 1 |
| Zheng, L | 1 |
| Pace, F | 1 |
| Maurano, A | 1 |
| Ciacci, C | 1 |
| Savarino, V | 1 |
| Attili, A | 1 |
| Iaquinto, G | 1 |
| Magni, E | 1 |
| Porro, GB | 1 |
1 trial available for diazepam and Irritable Bowel Syndrome
| Article | Year |
|---|---|
Octatropine methyl bromide and diazepam combination (Valpinax) in patients with irritable bowel syndrome: a multicentre, randomized, placebo-controlled trial.
Topics: Abdominal Pain; Adolescent; Adult; Aged; Defecation; Diazepam; Double-Blind Method; Drug Combination | 2010 |
1 other study available for diazepam and Irritable Bowel Syndrome
| Article | Year |
|---|---|
The effect of curcumin on the brain-gut axis in rat model of irritable bowel syndrome: involvement of 5-HT-dependent signaling.
Topics: Animals; Anxiety; Brain-Derived Neurotrophic Factor; Colon; Curcumin; Cyclic AMP Response Element-Bi | 2015 |