diazepam has been researched along with Intellectual Disability in 44 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this retrospective study of institutionalized patients with mental retardation, we present the efficacy and safety of sequential treatment with intrarectal diazepam (IRD) gel (Diastat) and intravenous levetiracetam (IVL) in comparison with either treatment alone for acute repetitive or prolonged seizures (ARPS)." | 7.76 | Sequential intrarectal diazepam and intravenous levetiracetam in treating acute repetitive and prolonged seizures. ( Milteer, WE; Modur, PN; Zhang, S, 2010) |
| "In this retrospective study of institutionalized patients with mental retardation, we present the efficacy and safety of sequential treatment with intrarectal diazepam (IRD) gel (Diastat) and intravenous levetiracetam (IVL) in comparison with either treatment alone for acute repetitive or prolonged seizures (ARPS)." | 3.76 | Sequential intrarectal diazepam and intravenous levetiracetam in treating acute repetitive and prolonged seizures. ( Milteer, WE; Modur, PN; Zhang, S, 2010) |
| " He developed neuroleptic malignant syndrome (NMS) which was treated successfully with intravenous diazepam." | 3.69 | Catatonic syndrome following recovery from neuroleptic malignant syndrome. ( Dent, J, 1995) |
| "He had pseudobulbar palsy, mental retardation, and intractable epilepsy." | 1.30 | Nonconvulsive status epilepticus in a child with congenital bilateral perisylvian syndrome. ( Itagaki, Y; Kobayashi, M; Sano, T; Sumi, K; Tagawa, T, 1999) |
| "Indications for this were mental retardation and dental fear." | 1.28 | General anaesthesia of out-patients in pedodontics. ( Dénes, J; Mikecz, G; Tarján, I, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (70.45) | 18.7374 |
| 1990's | 10 (22.73) | 18.2507 |
| 2000's | 2 (4.55) | 29.6817 |
| 2010's | 1 (2.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Modur, PN | 1 |
| Milteer, WE | 1 |
| Zhang, S | 1 |
| POELDINGER, W | 1 |
| BARSA, JA | 1 |
| SAUNDERS, JC | 1 |
| CARTER, CH | 1 |
| HARDER, A | 1 |
| GALAMBOS, M | 2 |
| Sonohata, M | 1 |
| Asami, A | 1 |
| Tsunoda, K | 1 |
| Hotokebuchi, T | 1 |
| Casier, H | 1 |
| Danechmand, L | 1 |
| De Schaepdryver, A | 1 |
| Hermans, W | 1 |
| Piette, Y | 1 |
| Lofterød, B | 1 |
| Asberg, A | 1 |
| Lossius, OP | 1 |
| Maier, U | 1 |
| Aigner, JM | 1 |
| Klein, HE | 1 |
| Brodtkorb, E | 2 |
| Sand, T | 1 |
| Kristiansen, A | 1 |
| Torbergsen, T | 1 |
| Dent, J | 1 |
| Fanning, B | 1 |
| Tagawa, T | 1 |
| Itagaki, Y | 1 |
| Kobayashi, M | 1 |
| Sano, T | 1 |
| Sumi, K | 1 |
| Viukari, M | 1 |
| Linnoila, M | 1 |
| Markand, ON | 1 |
| Irmisch, B | 1 |
| Pssler, J | 1 |
| Berman, W | 1 |
| Antila, H | 1 |
| Valli, J | 1 |
| Valtonen, M | 1 |
| Kanto, J | 1 |
| Sczesni, B | 1 |
| Becker, H | 1 |
| Schröder, J | 1 |
| Bittkau, S | 1 |
| von Baumgarten, F | 1 |
| Truong, DD | 1 |
| Przuntek, H | 1 |
| Davila, JM | 1 |
| Reiss, RA | 1 |
| Jensen, OE | 1 |
| Proskin, H | 1 |
| Tarján, I | 2 |
| Mikecz, G | 2 |
| Dénes, J | 2 |
| Ghaziuddin, N | 1 |
| Ghaziuddin, M | 1 |
| Asan, A | 1 |
| Knobel, G | 1 |
| Stene-Larsen, G | 1 |
| von Koskull, H | 1 |
| Aula, P | 1 |
| Ammälä, P | 1 |
| Nordström, AM | 1 |
| Rapola, J | 1 |
| Manning, DJ | 1 |
| Rosenbloom, L | 1 |
| Khanna, SS | 1 |
| Bharucha, B | 1 |
| Bhatia, AK | 1 |
| Dastur, FD | 1 |
| Macdonald, AG | 1 |
| Carmichael, AF | 1 |
| Litchfield, NB | 1 |
| Gibbs, FA | 1 |
| Anderson, EM | 1 |
| Lehmann, HE | 1 |
| Ban, TA | 1 |
| Partington, MW | 1 |
| Tu, JB | 1 |
| Wong, CY | 1 |
| Ucer, E | 1 |
| Niedermeyer, E | 1 |
| Martin, D | 1 |
| Healy, TE | 1 |
| Edmondson, HD | 1 |
| Hall, N | 1 |
| Lydecken, K | 1 |
| Rangdell, J | 1 |
| Palomäki, S | 1 |
| Campbell, ED | 1 |
| Green, EA | 1 |
| Dengler, K | 1 |
| Glaesel, HU | 1 |
| Ledoux, G | 1 |
| Serret, J | 1 |
| Reynes, M | 1 |
| Paracchi, G | 1 |
1 review available for diazepam and Intellectual Disability
| Article | Year |
|---|---|
[Hypothermia caused by neuroleptics. 2 case reports and review of the literature].
Topics: Administration, Oral; Adult; Antipsychotic Agents; Benperidol; Body Temperature; Diazepam; Dose-Resp | 1994 |
2 trials available for diazepam and Intellectual Disability
| Article | Year |
|---|---|
Treatment of hypsarrhythmia and infantile spasms with a librium analogue.
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Child; Child, Preschool; Chlordiazepoxide; Clinical Tr | 1965 |
Studies with new drugs in the treatment of convulsive disorders.
Topics: Adult; Aggression; Anticonvulsants; Anxiety; Carbamazepine; Clinical Trials as Topic; Diazepam; Dibe | 1968 |
41 other studies available for diazepam and Intellectual Disability
| Article | Year |
|---|---|
Sequential intrarectal diazepam and intravenous levetiracetam in treating acute repetitive and prolonged seizures.
Topics: Acute Disease; Administration, Rectal; Adult; Aged; Diazepam; Drug Therapy, Combination; Female; Hum | 2010 |
[CLINICAL EXPERIENCES WITH THE LIBRIUM ANALOGUE RO 5-2807 (VALIUM) IN PSYCHOTIC STATES].
Topics: Bipolar Disorder; Chlordiazepoxide; Diazepam; Humans; Intellectual Disability; Mental Disorders; Par | 1963 |
COMPARATIVE STUDY OF CHLORDIAZEPOXIDE AND DIAZEPAM.
Topics: Cerebral Palsy; Chlordiazepoxide; Diazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Int | 1964 |
A CONTROLLED EVALUATION OF TWO BENZODIAZEPINE DERIVATES IN THE MANAGEMENT OF MENTALLY RETARDED, CEREBRAL-PALSIED PATIENTS.
Topics: Adolescent; Anticonvulsants; Athetosis; Benzodiazepines; Biomedical Research; Cerebral Palsy; Child; | 1964 |
[CLINICAL EXPERIENCES WITH VALIUM ROCHE, A NEW BENZODIAZEPINE DERIVATIVE].
Topics: Antisocial Personality Disorder; Anxiety; Anxiety Disorders; Autonomic Nervous System Diseases; Benz | 1964 |
THE LONG-TERM USE OF VALIUM.
Topics: Depression; Depressive Disorder; Diazepam; Drug Therapy; Epilepsy; Intellectual Disability | 1965 |
LONG TERM CLINICAL TRIAL WITH DIAZEPAM ON ADULT MENTALLY RETARDED PERSONS.
Topics: Adult; Brain; Brain Damage, Chronic; Diazepam; Drug Therapy; Epilepsy; Epilepsy, Absence; Epilepsy, | 1965 |
Purple glove syndrome associated with intravenous phenytoin administration in a patient with severe mental and motor retardation.
Topics: Adolescent; Anticonvulsants; Comorbidity; Diazepam; Disabled Children; Extravasation of Diagnostic a | 2006 |
Blood alcohol levels and psychotropic drugs.
Topics: Adult; Aged; Chlorpromazine; Diazepam; Ethanol; Haloperidol; Humans; Imipramine; Intellectual Disabi | 1966 |
[Rectal administration of diazepam in solution in dental treatment of mentally retarded patients].
Topics: Adolescent; Adult; Anesthesia, Dental; Anesthesia, General; Child; Child, Preschool; Diazepam; Femal | 1982 |
Non-convulsive status epilepticus in the adult mentally retarded. Classification and role of benzodiazepines.
Topics: Adult; Aged; Anti-Anxiety Agents; Brain Damage, Chronic; Cerebral Cortex; Diazepam; Drug Therapy, Co | 1993 |
Catatonic syndrome following recovery from neuroleptic malignant syndrome.
Topics: Anti-Anxiety Agents; Antipsychotic Agents; Catatonia; Chlorpromazine; Diazepam; Dose-Response Relati | 1995 |
Experience with sedation and restraint during dental treatment in Romania.
Topics: Adolescent; Adult; Child; Conscious Sedation; Dental Anxiety; Dental Care for Children; Dental Care | 1995 |
Nonconvulsive status epilepticus in a child with congenital bilateral perisylvian syndrome.
Topics: Anticonvulsants; Brain; Cerebral Aqueduct; Child; Deglutition Disorders; Diazepam; Dysarthria; Elect | 1999 |
[Treatment with antiepileptic agents in patients with mental retardation and multiple handicaps].
Topics: Anticonvulsants; Antipsychotic Agents; Diazepam; Disabled Persons; Epilepsy; Humans; Intellectual Di | 2001 |
Serum medazepam, diazepam, and N-desmethyldiazepam levels after single and multiple oral doses of medazepam.
Topics: Administration, Oral; Adolescent; Adult; Anti-Anxiety Agents; Chemical Phenomena; Chemistry; Diazepa | 1977 |
Slow spike-wave activity in EEG and associated clinical features: often called 'Lennox' or "Lennox-Gastaut' syndrome.
Topics: Adolescent; Adult; Brain; Child; Child, Preschool; Diazepam; Electroencephalography; Epilepsy, Absen | 1977 |
[Experiences with premedication in the ambulatory stomatological treatment of difficult children].
Topics: Child; Child, Exceptional; Dental Care; Dentist-Patient Relations; Diazepam; Humans; Intellectual Di | 1976 |
Letter: The ketogenic diet, West and Lennox syndromes.
Topics: Child; Child, Preschool; Clonazepam; Diazepam; Humans; Infant; Intellectual Disability; Myoclonus; N | 1975 |
Comparison of propofol infusion and isoflurane for maintenance of anesthesia for dentistry in mentally retarded patients.
Topics: Adolescent; Adult; Analysis of Variance; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, | 1992 |
[Diagnostic and therapeutic aspects of neuroleptic malignant syndrome based on 12 cases].
Topics: Adult; Amantadine; Antipsychotic Agents; Bromocriptine; Dantrolene; Depressive Disorder; Diazepam; D | 1991 |
Chloral hydrate-diazepam: per os combination in treatment of disabled.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anesthesia, Dental; Chi-Square Distribution; Child; C | 1991 |
General anaesthesia of out-patients in pedodontics.
Topics: Adolescent; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthesia, General; Atropine; Child | 1990 |
Mania-like reaction induced by benzodiazepine withdrawal in a patient with mental retardation.
Topics: Adult; Bipolar Disorder; Diazepam; Dose-Response Relationship, Drug; Drug Administration Schedule; F | 1990 |
[Ambulatory anesthesia in pediatric dentistry].
Topics: Ambulatory Care; Anesthesia, Dental; Anesthesia, General; Atropine; Child; Child, Preschool; Dental | 1989 |
[Experiences with the use of levomepromazine and diazepam as premedication for dental treatment of the mentally handicapped].
Topics: Adolescent; Adult; Aged; Child; Dental Care for Disabled; Diazepam; Humans; Intellectual Disability; | 1986 |
Improved technique for the expression of fragile-X in cultured amniotic fluid cells.
Topics: Adult; Amniotic Fluid; Cells, Cultured; Chromosome Fragility; Diazepam; Female; Floxuridine; Humans; | 1985 |
Non-convulsive status epilepticus.
Topics: Anticonvulsants; Child; Child, Preschool; Chlormethiazole; Diazepam; Electroencephalography; Female; | 1987 |
Neonatal tetanus: psychomotor development in survivors.
Topics: Child; Child, Preschool; Diazepam; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Intel | 1985 |
The use of diazepam for conservative dentistry in handicapped children.
Topics: Anesthesia, Dental; Anesthesia, Intravenous; Child; Dentistry, Operative; Diazepam; Disabled Persons | 1970 |
Intravenous sedation in dental treatment of the handicapped. A preliminary report of 25 severely handicapped patients.
Topics: Anesthesia, Intravenous; Anesthesia, Local; Dental Care; Dentistry; Diazepam; Disabled Persons; Huma | 1974 |
Blood serotonin levels in severe mental retardation.
Topics: Age Factors; Blood Pressure; Child; Child, Preschool; Defecation; Diazepam; Diet; Female; Humans; Hy | 1973 |
Pilot study with RO 5-4556 in emotionally disturbed retarded children.
Topics: Adolescent; Benzazepines; Chemical Phenomena; Chemistry; Child; Child Behavior Disorders; Diazepam; | 1968 |
Intravenous diazepam and its anticonvulsive action.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Child, Preschool; Diazepam; Electroencephalography; | 1970 |
[Intravenous use of nitrazepam (Mogadan) in the treatment of epilepsy].
Topics: Administration, Oral; Benzazepines; Child; Child, Preschool; Diazepam; Electroencephalography; Epile | 1970 |
Sedation for the mentally handicapped dental patient.
Topics: Adolescent; Aggression; Anesthesia, Dental; Anesthesia, Local; Benperidol; Child; Child, Preschool; | 1971 |
[Experiences on premedication in dental treatment of CP- and mentally retarded patients].
Topics: Adolescent; Adult; Cerebral Palsy; Child; Child, Preschool; Chlorprothixene; Dental Restoration, Per | 1969 |
Treatment of cerebral palsy in the severely subnormal.
Topics: Carisoprodol; Cerebral Palsy; Child; Child, Preschool; Diazepam; Female; Humans; Hydrotherapy; Intel | 1970 |
[Use of valium in clinical psychiatry].
Topics: Alcoholism; Diazepam; Humans; Intellectual Disability; Psychotic Disorders; Substance-Related Disord | 1967 |
[Apropos of the use of diazepam (Valium) in the treatment of behavior disorders in profoundly retarded children. "Utilization in 32 children aged 9 to 14 years for 1 year"].
Topics: Adolescent; Child; Child Behavior Disorders; Diazepam; Humans; Intellectual Disability; Male | 1968 |
[Anxiety in oligophrenic children: physiologic and psychodynamic aspects].
Topics: Adolescent; Anxiety; Child; Child, Preschool; Diazepam; Female; Humans; Intellectual Disability; Mal | 1968 |