diazepam has been researched along with Idiopathic Parkinson Disease in 22 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 59-year-old man, who was diagnosed as having Parkinson's disease and depression seven years ago and was on oral antiparkinsonian agents, antianxiety agents, and antidepressants, developed a high fever, disturbed consciousness, and marked muscle rigidity after discontinuation of etizolam and amitriptyline." | 7.71 | [A patient with Parkinson's disease complicated by hypothyroidism who developed malignant syndrome after discontinuation of etizolam]. ( Araki, T; Esaki, S; Furuya, H; Inoue, N; Kawajiri, M; Kira, J; Ohyagi, Y; Yamada, T, 2002) |
| "A 59-year-old man, who was diagnosed as having Parkinson's disease and depression seven years ago and was on oral antiparkinsonian agents, antianxiety agents, and antidepressants, developed a high fever, disturbed consciousness, and marked muscle rigidity after discontinuation of etizolam and amitriptyline." | 3.71 | [A patient with Parkinson's disease complicated by hypothyroidism who developed malignant syndrome after discontinuation of etizolam]. ( Araki, T; Esaki, S; Furuya, H; Inoue, N; Kawajiri, M; Kira, J; Ohyagi, Y; Yamada, T, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (68.18) | 18.7374 |
| 1990's | 3 (13.64) | 18.2507 |
| 2000's | 3 (13.64) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Kan, HL | 1 |
| Tung, CW | 1 |
| Chang, SE | 1 |
| Lin, YC | 1 |
| Kawajiri, M | 1 |
| Ohyagi, Y | 1 |
| Furuya, H | 1 |
| Araki, T | 1 |
| Inoue, N | 1 |
| Esaki, S | 1 |
| Yamada, T | 1 |
| Kira, J | 1 |
| Meagher, LJ | 1 |
| McKay, D | 1 |
| Herkes, GK | 1 |
| Needham, M | 1 |
| Alonso-Navarro, H | 1 |
| Jiménez-Jiménez, FJ | 1 |
| Strang, RR | 1 |
| Kryzhanovskiĭ, GN | 1 |
| Isozaki, E | 1 |
| Hayashi, M | 1 |
| Hayashida, T | 1 |
| Tanabe, H | 1 |
| Hirai, S | 1 |
| Baumann, P | 1 |
| Cohen, CI | 1 |
| Mets, B | 1 |
| Frankel, JP | 1 |
| Hughes, A | 1 |
| Lees, AJ | 1 |
| Stern, GM | 1 |
| Pourcher, E | 1 |
| Bonnet, AM | 1 |
| Kefalos, J | 1 |
| Dubois, B | 1 |
| Agid, Y | 1 |
| Stern, J | 1 |
| Mendell, J | 1 |
| Clark, K | 1 |
| Papeschi, R | 1 |
| Molina-Negro, P | 1 |
| Sourkes, TL | 1 |
| Erba, G | 1 |
| Sigwald, J | 1 |
| Rondot, P | 1 |
| Raverdy, P | 1 |
| Singer, B | 1 |
| Lavy, S | 1 |
| Marks, ES | 1 |
| Abramsky, O | 1 |
| Markham, CH | 1 |
| Wodak, J | 1 |
| Gilligan, BS | 1 |
| Veale, JL | 1 |
| Dowty, BJ | 1 |
| Tyler, HR | 1 |
| Knopp, W | 1 |
| Diemath, HE | 1 |
| Enge, S | 1 |
| Lechner, H | 1 |
| Nathan, PW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Diagnostic Accuracy of Non-Contrast Computed Tomography in Correlation With Ultrasound in Detecting Acute Appendicitis in Adults[NCT05815446] | 78 participants (Anticipated) | Observational | 2023-04-20 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for diazepam and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
[ECT: The apple of discord in modern psychiatry (author's transl)].
Topics: Aggression; Anxiety; Atropine; Biogenic Amines; Confusion; Cyclic AMP; Depression; Diazepam; Electro | 1979 |
Advances in neurology.
Topics: Analgesics; Anticoagulants; Brain; Brain Neoplasms; Carbamazepine; Cerebrovascular Disorders; Contra | 1968 |
1 trial available for diazepam and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Psychiatric changes in patients treated with levodopa. I. The clinical experiment.
Topics: Activities of Daily Living; Adjustment Disorders; Aged; Amitriptyline; Clinical Trials as Topic; Dia | 1970 |
19 other studies available for diazepam and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
In silico prediction of parkinsonian motor deficits-related neurotoxicants based on the adverse outcome pathway concept.
Topics: Adverse Outcome Pathways; Animals; Diazepam; Electron Transport Complex I; Molecular Docking Simulat | 2022 |
[A patient with Parkinson's disease complicated by hypothyroidism who developed malignant syndrome after discontinuation of etizolam].
Topics: Antidepressive Agents; Depression; Diazepam; Humans; Hypothyroidism; Male; Middle Aged; Neuroleptic | 2002 |
Parkinsonism-hyperpyrexia syndrome: the role of electroconvulsive therapy.
Topics: Acetaminophen; Acyclovir; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Anxiety Agents; Anti-Ba | 2006 |
Panic attack like episodes possibly associated with pramipexole therapy in Parkinson's disease.
Topics: Anxiety Disorders; Benzothiazoles; Carbidopa; Central Nervous System; Diazepam; Dopamine Agonists; D | 2007 |
The symptom of restless legs.
Topics: Adult; Aged; Anemia, Hypochromic; Chlordiazepoxide; Diazepam; Female; Humans; Iron; Leg; Male; Middl | 1967 |
[Systems relations in neuropathology and psychiatry (various problems in treatment)].
Topics: Central Nervous System; Chorea; Diazepam; Epilepsy; Humans; Mental Disorders; Nervous System Disease | 1981 |
[Vocal cord abductor paralysis in multiple system atrophy--paradoxical movement of vocal cords during sleep].
Topics: Aged; Diazepam; Female; Fiber Optic Technology; Humans; Laryngoscopy; Male; Middle Aged; Movement; O | 1996 |
A case report: periodontal surgery in Parkinsonism utilizing intravenous sedation.
Topics: Aged; Anesthesia, Dental; Diazepam; Female; Humans; Injections, Intravenous; Parkinson Disease; Peri | 1978 |
Acute dystonia after alfentanil in untreated Parkinson's disease.
Topics: Aged; Alfentanil; Diazepam; Dystonia; Female; Humans; Parkinson Disease; Preanesthetic Medication | 1991 |
Marijuana for parkinsonian tremor.
Topics: Antiparkinson Agents; Apomorphine; Carbidopa; Diazepam; Drug Combinations; Humans; Levodopa; Marijua | 1990 |
Effects of etybenzatropine and diazepam on levodopa-induced diphasic dyskinesias in Parkinson's disease.
Topics: Diazepam; Humans; Levodopa; Middle Aged; Movement Disorders; Parkinson Disease; Pilot Projects; Trop | 1989 |
H reflex suppression by thalamic stimulation and drug administration.
Topics: Chlorpromazine; Diazepam; Electric Stimulation; Humans; Motor Neurons; Muscle Spindles; Oscillometry | 1968 |
The concentration of homovanillic and 5-hydroxyindoleacetic acids in ventricular and lumbar CSF. Studies in patients with extrapyramidal disorders, epilepsy, and other diseases.
Topics: Adolescent; Adult; Basal Ganglia Diseases; Cerebral Palsy; Cerebral Ventricles; Diazepam; Dihydroxyp | 1972 |
[Stiff man syndrome. Clinical, electrologic and therapeutic details].
Topics: Curare; Diagnosis, Differential; Diazepam; Electromyography; Emotions; Fatigue; Female; Humans; Midd | 1968 |
Parkinsonism and hyperthyroidism.
Topics: Diazepam; Dihydroxyphenylalanine; Drug Therapy, Combination; Female; Humans; Hyperthyroidism; Male; | 1974 |
The "on-off" side effect of L-DOPA.
Topics: Age Factors; Amitriptyline; Aromatic Amino Acid Decarboxylase Inhibitors; Athetosis; Carbidopa; Cate | 1974 |
Review of 12 months' treatment with L-dopa in Parkinson's disease, with remarks on unusual side effects.
Topics: Adult; Aged; Atrial Flutter; Body Weight; Deglutition Disorders; Diazepam; Dihydroxyphenylalanine; D | 1972 |
EEG depth leads during stereotaxic brain surgery. A report on 117 cases (5 target points, effects of 13 different drugs).
Topics: Amides; Amygdala; Antimetabolites; Asparagine; Benzoates; Brain; Brain Diseases; Cerebrovascular Cir | 1970 |
The action of diazepam in neurological disorders with excessive motor activity.
Topics: Brain Diseases; Decerebrate State; Diazepam; Diencephalon; Electromyography; Epilepsy; Hemiplegia; H | 1970 |