diazepam has been researched along with Hypothermia, Accidental in 24 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of the present paper was to remind physicians that hypothermia is a possible side-effect of combining zotepine, valproate,and benzodiazepine." | 7.72 | Two case studies of hypothermia induced by an increased dosage of zotepine in a combination therapy. ( Chen, KC; Chen, PS; Yang, MJ; Yang, YK; Yeh, TL, 2003) |
| "In the current study the link among the γ-hydroxybutyrate (GHB)/pentylenetetrazole (PTZ)-induced absence-like seizures and concomitant decreases in the core temperature, as well as electroencephalographic (EEG) activity during rewarming from deep hypothermia produced by a drug-free protocol were investigated." | 3.79 | GABAB receptors as a common target for hypothermia and spike and wave seizures: intersecting mechanisms of thermoregulation and absence epilepsy. ( Andjus, PR; Ilić, TV; Ostojić, ZS; Vesković, SM, 2013) |
| "The purpose of the present paper was to remind physicians that hypothermia is a possible side-effect of combining zotepine, valproate,and benzodiazepine." | 3.72 | Two case studies of hypothermia induced by an increased dosage of zotepine in a combination therapy. ( Chen, KC; Chen, PS; Yang, MJ; Yang, YK; Yeh, TL, 2003) |
| "Hypothermia is proposed to be an index of nausea in rats." | 1.43 | Autonomic changes induced by provocative motion in rats bred for high (HAB) and low (LAB) anxiety-related behavior: Paradoxical responses in LAB animals. ( Andrews, PL; Carnevali, L; Nalivaiko, E; Neumann, ID; Sgoifo, A, 2016) |
| "Pretreatment with diazepam completely prevents both penicillin-induced hypothermia and SWDs." | 1.30 | The connection between absence-like seizures and hypothermia induced by penicillin: possible implication on other animal models of petit mal epilepsy. ( Car, M; Ostojić, ZS; Rakić, L; Ruzdijić, S; Veskov, R, 1997) |
| " Fischer 344 rats were separated into multiple groups and underwent two dose-response evaluations." | 1.28 | Cerebral radioprotection by pentobarbital: dose-response characteristics and association with GABA agonist activity. ( Delaney, T; Friedman, R; Oldfield, EH; Olson, JJ; Orr, K, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (58.33) | 18.7374 |
| 1990's | 4 (16.67) | 18.2507 |
| 2000's | 3 (12.50) | 29.6817 |
| 2010's | 3 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ostojić, ZS | 2 |
| Ilić, TV | 1 |
| Vesković, SM | 1 |
| Andjus, PR | 1 |
| Carnevali, L | 1 |
| Andrews, PL | 1 |
| Neumann, ID | 1 |
| Nalivaiko, E | 1 |
| Sgoifo, A | 1 |
| Lkhagvasuren, B | 1 |
| Nakamura, Y | 1 |
| Oka, T | 1 |
| Sudo, N | 1 |
| Nakamura, K | 1 |
| Chen, KC | 1 |
| Yang, YK | 1 |
| Chen, PS | 1 |
| Yeh, TL | 1 |
| Yang, MJ | 1 |
| Echizenya, M | 1 |
| Mishima, K | 1 |
| Satoh, K | 1 |
| Kusanagi, H | 1 |
| Sekine, A | 1 |
| Ohkubo, T | 1 |
| Shimizu, T | 1 |
| Hishikawa, Y | 1 |
| Pietrzak, B | 1 |
| Czarnecka, E | 1 |
| Marsh, LA | 1 |
| Vidal, C | 1 |
| Suaudeau, C | 1 |
| Jacob, J | 1 |
| Vapaatalo, H | 1 |
| Hirvonen, J | 2 |
| Huttunen, P | 2 |
| Penttinen, J | 1 |
| Hammerle, AF | 1 |
| Hörtnagl, H | 1 |
| Geissler, D | 1 |
| Hackl, JM | 1 |
| Maier, U | 1 |
| Aigner, JM | 1 |
| Klein, HE | 1 |
| Ruzdijić, S | 1 |
| Car, M | 1 |
| Rakić, L | 1 |
| Veskov, R | 1 |
| Crabbe, JC | 1 |
| Gallaher, EJ | 1 |
| Cross, SJ | 1 |
| Belknap, JK | 1 |
| Rajtar, G | 1 |
| Naylor, GJ | 1 |
| McHarg, A | 1 |
| Posner, JB | 1 |
| Olson, JJ | 1 |
| Friedman, R | 1 |
| Orr, K | 1 |
| Delaney, T | 1 |
| Oldfield, EH | 1 |
| Okiyama, M | 1 |
| Ueno, K | 1 |
| Ohmori, S | 1 |
| Igarashi, T | 1 |
| Kitagawa, H | 1 |
| Joyce, DN | 1 |
| Kenyon, VG | 1 |
| Dunn, PM | 1 |
| Cardauns, H | 1 |
| Iffland, R | 1 |
| Mottram, PE | 1 |
| Johnson, PB | 1 |
| Hoffman, JE | 1 |
| Fell, RH | 1 |
| Dendy, PR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Thermoregulation Among Individuals With First-episode Psychosis[NCT04369677] | 20 participants (Anticipated) | Observational | 2023-11-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for diazepam and Hypothermia, Accidental
| Article | Year |
|---|---|
[Hypothermia caused by neuroleptics. 2 case reports and review of the literature].
Topics: Administration, Oral; Adult; Antipsychotic Agents; Benperidol; Body Temperature; Diazepam; Dose-Resp | 1994 |
23 other studies available for diazepam and Hypothermia, Accidental
| Article | Year |
|---|---|
GABAB receptors as a common target for hypothermia and spike and wave seizures: intersecting mechanisms of thermoregulation and absence epilepsy.
Topics: Animals; Anticonvulsants; Benzoates; Body Temperature Regulation; Cerebral Cortex; Diazepam; Epileps | 2013 |
Autonomic changes induced by provocative motion in rats bred for high (HAB) and low (LAB) anxiety-related behavior: Paradoxical responses in LAB animals.
Topics: Animals; Anticonvulsants; Anxiety; Autonomic Nervous System; Body Temperature; Breeding; Diazepam; D | 2016 |
Social defeat stress induces hyperthermia through activation of thermoregulatory sympathetic premotor neurons in the medullary raphe region.
Topics: Adrenergic beta-3 Receptor Antagonists; Analysis of Variance; Animals; Anti-Anxiety Agents; Body Tem | 2011 |
Two case studies of hypothermia induced by an increased dosage of zotepine in a combination therapy.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Diazepam; Diben | 2003 |
Enhanced heat loss and age-related hypersensitivity to diazepam.
Topics: Adolescent; Adult; Age Factors; Aged; Aging; Analysis of Variance; Body Temperature Regulation; Cros | 2004 |
Interaction between ethanol and diazepam in mice: chronobiological aspects.
Topics: Animals; Anti-Anxiety Agents; Body Temperature; Central Nervous System Depressants; Chronobiology Ph | 2005 |
Quality assurance activities in a small community hospital.
Topics: Blood Transfusion; Conjunctivitis; Cross Infection; Diazepam; Hospital Bed Capacity, under 100; Hosp | 1983 |
Hyper- and hypothermia induced by non-noxious stress: effects of naloxone, diazepam and gamma-acetylenic GABA.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Body Temperature; Diazepam; Humans; | 1983 |
Lowered cold tolerance in cold-acclimated and non-acclimated guinea pigs treated with diazepam.
Topics: Acclimatization; Animals; Blood Glucose; Body Temperature Regulation; Cold Temperature; Diazepam; Fa | 1984 |
Histologically demonstrable vital reactions to frostbite in guinea pigs dying of hypothermia.
Topics: Acclimatization; Animals; Capillaries; Diazepam; Edema; Ethanol; Frostbite; Guinea Pigs; Hypothermia | 1982 |
[Plasma catecholamines in accidental hypothermia (author's transl)].
Topics: Adult; Alcoholism; Child, Preschool; Diazepam; Epinephrine; Humans; Hypothermia; Male; Middle Aged; | 1980 |
The connection between absence-like seizures and hypothermia induced by penicillin: possible implication on other animal models of petit mal epilepsy.
Topics: Animals; Anticonvulsants; Body Temperature; Cerebral Cortex; Diazepam; Disease Models, Animal; Elect | 1997 |
Genetic determinants of sensitivity to diazepam in inbred mice.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Ataxia; Brain; Diazepam; Disease Susceptibility; | 1998 |
The influence of chlorpromazine, diazepam and imipramine on the central action of ethanol.
Topics: Animals; Chlorpromazine; Diazepam; Drug Synergism; Ethanol; Hypothermia; Imipramine; Lethal Dose 50; | 1977 |
Profound hypothermia on combined lithium carbonate and diazepam treatment.
Topics: Adult; Diazepam; Drug Synergism; Drug Therapy, Combination; Female; Humans; Hypothermia; Lithium | 1977 |
The comatose patient.
Topics: Coma; Dexamethasone; Diazepam; Emergencies; Fever; Glucose; Humans; Hypothermia; Intracranial Pressu | 1975 |
Cerebral radioprotection by pentobarbital: dose-response characteristics and association with GABA agonist activity.
Topics: Anesthesia, General; Animals; Brain; Diazepam; Dose-Response Relationship, Drug; Dose-Response Relat | 1990 |
Drug interactions between imipramine and benzodiazepines in rats.
Topics: Animals; Anti-Anxiety Agents; Blood Proteins; Brain; Chromatography, High Pressure Liquid; Desiprami | 1988 |
The use of diazepam and hydrallazine in the treatment of severe pre-eclampsia.
Topics: Adult; Blood Pressure; Diazepam; Ethanol; Female; Gestational Age; Humans; Hydralazine; Hypothermia; | 1972 |
"The newborn, now or never".
Topics: Adult; Asphyxia Neonatorum; Diazepam; Female; Hip Dislocation, Congenital; Humans; Hypothermia; Infa | 1973 |
[Fatal intoxication of a young drug addict with diazepam (author's transl)].
Topics: Adolescent; Alcoholic Intoxication; Autopsy; Diazepam; Humans; Hypothermia; Lethal Dose 50; Male; Su | 1973 |
Isoniazid toxicity. Reversal with pyridoxine.
Topics: Adolescent; Diazepam; Humans; Hyperglycemia; Hypothermia; Isoniazid; Lactates; Male; Pyridoxine; Sei | 1974 |
Severe hypothermia and respiratory arrest in diazepam and glutethimide intoxication.
Topics: Adult; Apnea; Body Temperature; Carbon Dioxide; Diazepam; Diuresis; Female; Glutethimide; Heart; Hum | 1968 |