Page last updated: 2024-10-25

diazepam and Hyperphagia

diazepam has been researched along with Hyperphagia in 9 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Hyperphagia: Ingestion of a greater than optimal quantity of food.

Research Excerpts

ExcerptRelevanceReference
"The present trial examined the possibility that diazepam (DZP, 1 mg/kg) induces hyperphagia by acting on the dopaminergic system."7.70Diazepam-induced hyperphagia in mice is sensitive to quinpirole. ( Nishimura, M; Rahminiwati, M, 1999)
"We investigated whether histaminergic neurons in the brain are involved in diazepam-induced hyperphagia in rats."7.69Relationship between histamine receptors in the brain and diazepam-induced hyperphagia in rats. ( Ishii, R; Naruse, T, 1995)
"Possible involvement of dopamine receptors in diazepam-induced (1 mg/kg, subcutaneous (sc] hyperphagia was studied in nondeprived rats."7.68Possible involvement of dopamine D-1 and D-2 receptors in diazepam-induced hyperphagia in rats. ( Amano, H; Koizumi, Y; Naruse, T, 1991)
" Interestingly, benzodiazepine receptor antagonist flumazenil (5 ng/rat, icv), augmented the orexin-A (30 nM/rat, icv) induced hyperphagia; the effect may be attributed to the intrinsic activity of the agent."3.73GABA(A) receptors mediate orexin-A induced stimulation of food intake. ( Carta, A; Chopde, CT; Kokare, DM; Patole, AM; Subhedar, NK, 2006)
"The present trial examined the possibility that diazepam (DZP, 1 mg/kg) induces hyperphagia by acting on the dopaminergic system."3.70Diazepam-induced hyperphagia in mice is sensitive to quinpirole. ( Nishimura, M; Rahminiwati, M, 1999)
"Possible involvement of dopamine receptors in diazepam-induced (1 mg/kg, subcutaneous (sc] hyperphagia was studied in nondeprived rats."3.68Possible involvement of dopamine D-1 and D-2 receptors in diazepam-induced hyperphagia in rats. ( Amano, H; Koizumi, Y; Naruse, T, 1991)
" This article reports an acute organic psychosis marked by visual, auditory, and tactile hallucinations after abrupt discontinuation of phenelzine in two young women without previous history of psychotic symptoms."3.67Acute psychosis following phenelzine discontinuation. ( Jackson, WK; Liskin, B; Roose, SP; Walsh, BT, 1985)
"treatment with diazepam induces hyperphagia showing no tolerance accompanied by an increase in body weight, thus resulting in a trend toward obesity in rats."1.29Effects of repeated intravenous administration of diazepam on food intake in rats. ( Naruse, T, 1994)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's4 (44.44)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Morris, HV1
Nilsson, S1
Dixon, CI1
Stephens, DN1
Clifton, PG1
Kokare, DM1
Patole, AM1
Carta, A1
Chopde, CT1
Subhedar, NK1
Naruse, T4
Ishii, R1
Rahminiwati, M1
Nishimura, M1
Amano, H1
Koizumi, Y2
Van Miert, AS1
Koot, M1
Van Duin, CT1
Asami, T1
Liskin, B1
Roose, SP1
Walsh, BT1
Jackson, WK1

Other Studies

9 other studies available for diazepam and Hyperphagia

ArticleYear
Alpha1- and alpha2-containing GABAA receptor modulation is not necessary for benzodiazepine-induced hyperphagia.
    Appetite, 2009, Volume: 52, Issue:3

    Topics: Analysis of Variance; Animals; Benzodiazepines; Diazepam; Dose-Response Relationship, Drug; Energy I

2009
GABA(A) receptors mediate orexin-A induced stimulation of food intake.
    Neuropharmacology, 2006, Volume: 50, Issue:1

    Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Eating; Flumazenil; GABA Agonists; GABA Antagon

2006
Relationship between histamine receptors in the brain and diazepam-induced hyperphagia in rats.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 51, Issue:4

    Topics: Animals; Brain Chemistry; Diazepam; Food Deprivation; Histamine Agonists; Histamine Antagonists; His

1995
Effects of repeated intravenous administration of diazepam on food intake in rats.
    Fundamental & clinical pharmacology, 1994, Volume: 8, Issue:4

    Topics: Animals; Body Weight; Darkness; Diazepam; Dose-Response Relationship, Drug; Eating; Hyperphagia; Inf

1994
Diazepam-induced hyperphagia in mice is sensitive to quinpirole.
    The Journal of veterinary medical science, 1999, Volume: 61, Issue:7

    Topics: Animals; Diazepam; Dopamine Agonists; Feeding Behavior; Hyperphagia; Mice; Quinpirole; Receptors, Do

1999
Possible involvement of dopamine D-1 and D-2 receptors in diazepam-induced hyperphagia in rats.
    Fundamental & clinical pharmacology, 1991, Volume: 5, Issue:8

    Topics: alpha-Methyltyrosine; Animals; Benzamides; Benzazepines; Diazepam; Domperidone; Dose-Response Relati

1991
Appetite-modulating drugs in dwarf goats, with special emphasis on benzodiazepine-induced hyperphagia and its antagonism by flumazenil and RO 15-3505.
    Journal of veterinary pharmacology and therapeutics, 1989, Volume: 12, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Appetite Regulation; Azepines; Benzodiazepines; Benzodiazepinones; Bod

1989
Effects of naloxone and picrotoxin on diazepam- or pentobarbital-induced hyperphagia in nondeprived rats.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:3

    Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Feeding Behavior; Hyperphagia; Male; Naloxone;

1988
Acute psychosis following phenelzine discontinuation.
    Journal of clinical psychopharmacology, 1985, Volume: 5, Issue:1

    Topics: Acute Disease; Adult; Diazepam; Female; Hallucinations; Humans; Hyperphagia; Phenelzine; Psychotic D

1985