diazepam has been researched along with Hypercapnia in 14 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In view of the fact that diazepam has been shown to prevent an increase in catecholamine synthesis and/or turnover rates in stressful situations, and to modify the cerebral metabolic (and circulatory) response to hypoxia and hypercapnia, the influence of the drug on synthesis rates of DOPA and 5-HTP in three regions of the rat brain were studied under normoxic-normocapnic conditions, as well as in hypoxia and hypercapnia." | 7.66 | Effect of diazepam on cerebral monoamine synthesis during hypoxia and hypercapnia in the rat. ( Carlsson, A; Dahlgren, N; Sakabe, T; Siesjö, BK, 1982) |
| "In view of the fact that diazepam has been shown to prevent an increase in catecholamine synthesis and/or turnover rates in stressful situations, and to modify the cerebral metabolic (and circulatory) response to hypoxia and hypercapnia, the influence of the drug on synthesis rates of DOPA and 5-HTP in three regions of the rat brain were studied under normoxic-normocapnic conditions, as well as in hypoxia and hypercapnia." | 3.66 | Effect of diazepam on cerebral monoamine synthesis during hypoxia and hypercapnia in the rat. ( Carlsson, A; Dahlgren, N; Sakabe, T; Siesjö, BK, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (92.86) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Siesjö, BK | 3 |
| Jordan, C | 1 |
| Lehane, JR | 1 |
| Jones, JG | 1 |
| Delpierre, S | 1 |
| Jammes, Y | 1 |
| Grimaud, C | 1 |
| Dugué, P | 1 |
| Arnaud, A | 1 |
| Charpin, J | 1 |
| Sakabe, T | 1 |
| Dahlgren, N | 2 |
| Carlsson, A | 1 |
| Flecknell, PA | 1 |
| John, M | 1 |
| Mitchell, M | 1 |
| Shurey, C | 1 |
| Simpkin, S | 1 |
| Fujiya, S | 1 |
| Mak, KH | 1 |
| Wang, YT | 1 |
| Cheong, TH | 1 |
| Poh, SC | 1 |
| Berntman, L | 1 |
| Sedgwick, CJ | 1 |
| Lakshminarayan, S | 1 |
| Sahn, SA | 1 |
| Hudson, LD | 1 |
| Weil, JV | 1 |
| Kronenberg, RS | 1 |
| Cosio, MG | 1 |
| Stevenson, JE | 1 |
| Drage, CW | 1 |
| St John, WM | 1 |
| Bledsoe, TA | 1 |
| Keith, L | 1 |
| Silver, A | 1 |
| Becker, M | 1 |
1 review available for diazepam and Hypercapnia
| Article | Year |
|---|---|
Cerebral metabolic rate in hypercarbia--a controversy.
Topics: Amino Acids; Animals; Brain; Carbon Dioxide; Cerebrovascular Circulation; Citric Acid Cycle; Diazepa | 1980 |
2 trials available for diazepam and Hypercapnia
| Article | Year |
|---|---|
Respiratory depression following diazepam: reversal with high-dose naloxone.
Topics: Adult; Carbon Dioxide; Diazepam; Dose-Response Relationship, Drug; Humans; Hypercapnia; Middle Aged; | 1980 |
Influence of anxiolytic drugs (Prazepam and Diazepam) on respiratory center output and CO2 chemosensitivity in patients with lung diseases.
Topics: Asthma; Bronchitis; Carbon Dioxide; Diazepam; Female; Humans; Hypercapnia; Lung Diseases; Male; Midd | 1981 |
11 other studies available for diazepam and Hypercapnia
| Article | Year |
|---|---|
Effect of diazepam on cerebral monoamine synthesis during hypoxia and hypercapnia in the rat.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Brain; Cerebrovascular Circulation; Diazepam; Dihydroxyph | 1982 |
Neuroleptanalgesia in the rabbit.
Topics: Acidosis; Animals; Butyrophenones; Diazepam; Drug Combinations; Etorphine; Fentanyl; Hypercapnia; Me | 1983 |
[Characteristics of respiratory physiology in a case of stiff-man syndrome (author's transl)].
Topics: Diazepam; Humans; Hypercapnia; Male; Middle Aged; Muscle Rigidity; Respiration; Respiratory Function | 1981 |
The effect of oral midazolam and diazepam on respiration in normal subjects.
Topics: Administration, Oral; Analysis of Variance; Diazepam; Humans; Hypercapnia; Hypoxia; Male; Midazolam; | 1993 |
Cerebral blood flow and oxygen consumption in the rat brain during extreme hypercarbia.
Topics: Adrenalectomy; Animals; Blood Gas Analysis; Blood Pressure; Brain; Carbon Dioxide; Diazepam; Hydroge | 1979 |
Field anesthesia in stressed animals.
Topics: Acepromazine; Acidosis; Anesthesia; Animals; Animals, Zoo; Artiodactyla; Diazepam; Etorphine; Fever; | 1979 |
Effect of diazepam on ventilatory responses.
Topics: Adolescent; Adult; Diazepam; Female; Humans; Hypercapnia; Hypoxia; Male; Respiration; Time Factors | 1976 |
Letter: The use of oral diazepam in patients with obstructive lung disease and hypercapnia.
Topics: Administration, Oral; Diazepam; Humans; Hypercapnia; Lung Diseases, Obstructive | 1975 |
Comparison of respiratory-related trigeminal, hypoglossal and phrenic activities.
Topics: Animals; Cats; Chemoreceptor Cells; Decerebrate State; Diazepam; Doxapram; Electromyography; Electro | 1985 |
Anesthesia for laparoscopy.
Topics: Alphaprodine; Anesthesia; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Local; Anesthetics; | 1974 |
The lazy respiratory center--or how to recognize a tired horse. Clinical conference in pulmonary disease from Northwestern University-McGaw Medical Center, Chicago.
Topics: Brain Diseases; Chemoreceptor Cells; Chronic Disease; Diagnosis, Differential; Diazepam; Digoxin; Fu | 1974 |