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diazepam and Hyperactivity, Motor

diazepam has been researched along with Hyperactivity, Motor in 24 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Research Excerpts

ExcerptRelevanceReference
"Levetiracetam (LEV) is a structurally novel antiepileptic drug (AED) which has demonstrated a broad spectrum of anticonvulsant activities both in experimental and clinical studies."5.34Prophylactic treatment with levetiracetam after status epilepticus: lack of effect on epileptogenesis, neuronal damage, and behavioral alterations in rats. ( Bethmann, K; Brandt, C; Fedrowitz, M; Gastens, AM; Glien, M; Löscher, W; Potschka, H; Volk, HA, 2007)
"We have shown previously that aberrant hippocampal (HPC) output underlies the dopamine (DA) dysfunction observed in the methylazoxymethanol acetate (MAM) developmental model of schizophrenia in the rodent."3.77A novel α5GABA(A)R-positive allosteric modulator reverses hyperactivation of the dopamine system in the MAM model of schizophrenia. ( Aras, S; Cook, JM; Gill, KM; Grace, AA; Lodge, DJ, 2011)
"Continued usage of cocaine is determined by genetic, conditioned and homeostatic factors, while it is reinforced by drug-induced reward and the emotionally negative state of drug withdrawal, which includes anxiety."3.74Anxiogenic effects of cocaine withdrawal in zebrafish. ( Cabral, H; López-Patiño, MA; Yu, L; Zhdanova, IV, 2008)
" By measuring the brain function using computer period analysis of cerebral biopotentials, dose-efficacy relations were found (in the range of 25-75 mcg) which suggest the bioavailability of LHM at the CNS level."2.64Prediction of psychotropic properties of lisuride hydrogen maleate by quantitative pharmaco-electroencephalogram. ( Akpinar, S; Herrmann, WM; Itil, TM, 1975)
" Amphetamine and diazepam produced an inverted U-shaped dose-response effect on different parameters of the test and demonstrate that the drug concentration which elicited a peak in mean number of entries is different from the drug concentration which elicited a peak in mean duration of entries."1.36Distinguishing anxiolysis and hyperactivity in an open space behavioral test. ( Chazot, PL; Ennaceur, A; Michalikova, S; van Rensburg, R, 2010)
"Levetiracetam (LEV) is a structurally novel antiepileptic drug (AED) which has demonstrated a broad spectrum of anticonvulsant activities both in experimental and clinical studies."1.34Prophylactic treatment with levetiracetam after status epilepticus: lack of effect on epileptogenesis, neuronal damage, and behavioral alterations in rats. ( Bethmann, K; Brandt, C; Fedrowitz, M; Gastens, AM; Glien, M; Löscher, W; Potschka, H; Volk, HA, 2007)
" The concomitant administration of diazepam inhibited the morphine-induced hyperactivity and the diazepam administration prior to and during the chronic administration of morphine in mice inhibited the development of reverse tolerance to the hyperactivity of morphine (10 mg x kg(-1), s."1.31Inhibition of diazepam on morphine-induced hyperactivity, reverse tolerance and postsynaptic dopamine receptor supersensitivity. ( Kim, HS; Woo, SH, 2001)
" However, chronic administration for 21 days produced tolerance and no significant change in the ambulatory and total activity."1.29Reversal of diazepam withdrawal induced hyperactivity in mice by BR 16-A (Mentat), a herbal preparation. ( Kulkarni, SK; Sharma, A, 1994)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199016 (66.67)18.7374
1990's1 (4.17)18.2507
2000's5 (20.83)29.6817
2010's2 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ennaceur, A1
Michalikova, S1
van Rensburg, R1
Chazot, PL1
Gill, KM1
Lodge, DJ1
Cook, JM1
Aras, S1
Grace, AA1
Lu, YJ1
Zhou, J1
Zhang, SM1
Zhang, HY1
Zheng, XX1
Brandt, C1
Glien, M1
Gastens, AM1
Fedrowitz, M1
Bethmann, K1
Volk, HA1
Potschka, H1
Löscher, W1
López-Patiño, MA1
Yu, L1
Cabral, H1
Zhdanova, IV1
Morris, HV1
Dawson, GR1
Reynolds, DS1
Atack, JR1
Rosahl, TW1
Stephens, DN1
Kulkarni, SK1
Sharma, A1
Woo, SH1
Kim, HS1
Drtílková, I1
Náhunek, K1
Machácková, V1
Podhradská, O1
Haddad, LM1
Itil, TM1
Herrmann, WM1
Akpinar, S1
Amoia, M1
Azzollini, CV1
Ippedico, M1
Donadio, S1
Crawford, TI1
Kuzemko, JA1
Hartley, S1
Burnett, LL1
Struve, FA1
Wodak, J1
Gilligan, BS1
Veale, JL1
Dowty, BJ1
Haidvogl, M1
Wendler, H1
Diemath, HE1
Enge, S1
Lechner, H1
Witzel, K1
Howell, MC1
Rever, GW1
Scholl, ML1
Trowbridge, F1
Rutledge, A1
Healy, TE1
Edmondson, HD1
Hall, N1
Tinklenberg, JR1
Ott, T1
Matthies, H1
Aho, K1
Fogelholm, R1
Waltimo, O1

Reviews

1 review available for diazepam and Hyperactivity, Motor

ArticleYear
The value of EEG study in minimal brain dysfunction.
    Journal of clinical psychology, 1974, Volume: 30, Issue:4

    Topics: Attention Deficit Disorder with Hyperactivity; Child Behavior Disorders; Chlordiazepoxide; Diagnosis

1974

Trials

4 trials available for diazepam and Hyperactivity, Motor

ArticleYear
Controlled comparison of the effect of dosulepin and diazepam in hyperkinetic children with phenylketonuria.
    Activitas nervosa superior, 1978, Volume: 20, Issue:4

    Topics: Child; Clinical Trials as Topic; Diazepam; Dibenzothiepins; Dothiepin; Double-Blind Method; Female;

1978
Prediction of psychotropic properties of lisuride hydrogen maleate by quantitative pharmaco-electroencephalogram.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:1-2

    Topics: Adolescent; Adult; Aged; Biological Availability; Child; Child, Preschool; Clinical Trials as Topic;

1975
Preanesthetic medication in elective surgery: comparison of intravenous diazepam with meperidine.
    Current therapeutic research, clinical and experimental, 1973, Volume: 15, Issue:7

    Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Anxiety; Blood Pressure; Child; Clinical Trials as

1973
Treatment of cerebral irritation in the newborn: double-blind trial with chloral hydrate and diazepam.
    Developmental medicine and child neurology, 1972, Volume: 14, Issue:6

    Topics: Asphyxia Neonatorum; Body Weight; Brain Diseases; Chloral Hydrate; Clinical Trials as Topic; Diazepa

1972

Other Studies

19 other studies available for diazepam and Hyperactivity, Motor

ArticleYear
Distinguishing anxiolysis and hyperactivity in an open space behavioral test.
    Behavioural brain research, 2010, Feb-11, Volume: 207, Issue:1

    Topics: Amphetamine; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Central

2010
A novel α5GABA(A)R-positive allosteric modulator reverses hyperactivation of the dopamine system in the MAM model of schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:9

    Topics: Allosteric Regulation; Amphetamine; Animals; Benzodiazepines; Diazepam; Disease Models, Animal; Dopa

2011
Inhibitory effects of jujuboside A on EEG and hippocampal glutamate in hyperactive rat.
    Journal of Zhejiang University. Science. B, 2005, Volume: 6, Issue:4

    Topics: Animals; Behavior, Animal; Diazepam; Electroencephalography; Glutamic Acid; Hippocampus; Hyperkinesi

2005
Prophylactic treatment with levetiracetam after status epilepticus: lack of effect on epileptogenesis, neuronal damage, and behavioral alterations in rats.
    Neuropharmacology, 2007, Volume: 53, Issue:2

    Topics: Amygdala; Analysis of Variance; Animals; Anticonvulsants; Behavior, Animal; Brain Damage, Chronic; D

2007
Anxiogenic effects of cocaine withdrawal in zebrafish.
    Physiology & behavior, 2008, Jan-28, Volume: 93, Issue:1-2

    Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Cocaine; Diazepam; Disease Models, Anim

2008
Alpha2-containing GABA(A) receptors are involved in mediating stimulant effects of cocaine.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 90, Issue:1

    Topics: Animals; Autoradiography; Azides; Benzodiazepines; Brain Chemistry; Central Nervous System Stimulant

2008
Reversal of diazepam withdrawal induced hyperactivity in mice by BR 16-A (Mentat), a herbal preparation.
    Indian journal of experimental biology, 1994, Volume: 32, Issue:12

    Topics: Animals; Diazepam; Female; Hyperkinesis; Male; Medicine, Ayurvedic; Mice; Plant Extracts; Plants, Me

1994
Inhibition of diazepam on morphine-induced hyperactivity, reverse tolerance and postsynaptic dopamine receptor supersensitivity.
    Pharmacological research, 2001, Volume: 44, Issue:6

    Topics: Animals; Apomorphine; Diazepam; Dopamine; Dopamine Agonists; Drug Tolerance; GABA Agonists; Hyperkin

2001
Management of hallucinogen abuse.
    American family physician, 1976, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Amphetamines; Basidiomycota; Cannabis; Child; Condiments; Diazepam; Fruit; Halluc

1976
[Hyperkinetic effects of flunitrazepam and diazepam on the fetus].
    Minerva anestesiologica, 1987, Volume: 53, Issue:4

    Topics: Diazepam; Drug Interactions; Female; Fetal Movement; Flunitrazepam; Heart Rate; Humans; Hyperkinesis

1987
Review of 12 months' treatment with L-dopa in Parkinson's disease, with remarks on unusual side effects.
    The Medical journal of Australia, 1972, Dec-02, Volume: 2, Issue:23

    Topics: Adult; Aged; Atrial Flutter; Body Weight; Deglutition Disorders; Diazepam; Dihydroxyphenylalanine; D

1972
[The dystonic-hyperkinetic syndrome. A case report on the knowledge of drug side-effects in children].
    Wiener medizinische Wochenschrift (1946), 1974, Apr-27, Volume: 124, Issue:17

    Topics: Adolescent; Child; Diazepam; Drug Hypersensitivity; Female; Humans; Hyperkinesis; Male; Metocloprami

1974
EEG depth leads during stereotaxic brain surgery. A report on 117 cases (5 target points, effects of 13 different drugs).
    Confinia neurologica, 1970, Volume: 32, Issue:2

    Topics: Amides; Amygdala; Antimetabolites; Asparagine; Benzoates; Brain; Brain Diseases; Cerebrovascular Cir

1970
[Paspertin (Metoclopramide) as a cause of dystonic-hyperkinetic syndromes in children].
    Monatsschrift fur Kinderheilkunde, 1972, Volume: 120, Issue:2

    Topics: Amides; Benzoates; Biperiden; Child; Diazepam; Female; Gastrointestinal Diseases; Humans; Hyperkines

1972
Hyperactivity in children: types, diagosis, drug therapy, approaches to management.
    Clinical pediatrics, 1972, Volume: 11, Issue:1

    Topics: Amphetamine; Anxiety; Attention; Attention Deficit Disorder with Hyperactivity; Brain Damage, Chroni

1972
Sedation for the mentally handicapped dental patient.
    Anaesthesia, 1971, Volume: 26, Issue:3

    Topics: Adolescent; Aggression; Anesthesia, Dental; Anesthesia, Local; Benperidol; Child; Child, Preschool;

1971
A clinical view of the amphetamines.
    American family physician, 1971, Volume: 4, Issue:5

    Topics: Amphetamine; Appetite Depressants; Central Nervous System Diseases; Depression; Diazepam; Hospitaliz

1971
[Differentiation of neuroleptic and psychosedative effects in screening].
    Acta biologica et medica Germanica, 1969, Volume: 22, Issue:5

    Topics: Animals; Chlordiazepoxide; Chlorpromazine; Depression, Chemical; Diazepam; Humans; Hyperkinesis; Hyp

1969
[Hyperkinetic syndromes during antivertiginous treatment].
    Duodecim; laaketieteellinen aikakauskirja, 1971, Volume: 87, Issue:7

    Topics: Adolescent; Adult; Barbiturates; Chlormezanone; Diagnosis, Differential; Diazepam; Female; Humans; H

1971