diazepam has been researched along with Heroin Abuse in 35 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Drug addiction during pregnancy has been managed in two ways: the detoxification program and the methadone-maintenance treatment program." | 3.65 | Drug addiction in pregnancy and the neonate. ( Ackerman, BD; Blinick, G; Jerez, E; Wallach, RC, 1976) |
| "This is a case report of a CPP treated by a pain physician." | 1.35 | Alleged breaches of "standards of medical care" in a patient overdose death possibly related to chronic opioid analgesic therapy, application of the controlled substances model guidelines: case report. ( Cole, B; Fishbain, DA; Gao, J; Lewis, JE; Rosomoff, RS, 2009) |
| "Methadone is a well-established maintenance drug for the therapy of opioid addicts." | 1.32 | [Intoxication with methadone and benzodiazepines in a morbidly obese patient in the social environment of a heroin addict receiving methadone maintenance therapy]. ( Hammer, B; Kleinschmidt, S; Risch, B; Wilhelm, W, 2004) |
| "Methadone maintenance patients who use benzodiazepine drugs were interviewed about the dosage levels, patterns, frequency and motives for their use of these drugs." | 1.26 | Diazepam use among methadone maintenance patients: patterns and dosages. ( Grabowski, J; Griffiths, RR; Hawthorne, JW; McLellan, AT; Stitzer, ML, 1981) |
| "Thrombocytosis was not related to withdrawal symptoms or treatment (phenobarbital or paregoric)." | 1.26 | Thrombocytosis and increased circulating platelet aggregates in newborn infants of polydrug users. ( Burstein, Y; Giardina, PJ; Kandall, SR; Peterson, CM; Rausen, AR; Siljestrom, K, 1979) |
| " It is suggested that reduction of methadone dosage in late pregnancy results in reduced incidence of withdrawal but must be carefully carried out." | 1.26 | Observation and treatment of neonatal narcotic withdrawal. ( Chappel, JN; Davis, R; Gumpel, J; Madden, JD; Mejia, A; Zuspan, F, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (74.29) | 18.7374 |
| 1990's | 2 (5.71) | 18.2507 |
| 2000's | 6 (17.14) | 29.6817 |
| 2010's | 1 (2.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fishbain, DA | 1 |
| Lewis, JE | 1 |
| Gao, J | 1 |
| Cole, B | 1 |
| Rosomoff, RS | 1 |
| Laqueille, X | 1 |
| Launay, C | 1 |
| Dervaux, A | 1 |
| Kanit, M | 1 |
| Moller, M | 1 |
| Koren, G | 1 |
| Man, LH | 1 |
| Best, D | 1 |
| Gossop, M | 1 |
| Stillwell, G | 1 |
| Strang, J | 2 |
| Kleinschmidt, S | 1 |
| Wilhelm, W | 1 |
| Risch, B | 1 |
| Hammer, B | 1 |
| Fatséas, M | 1 |
| Lavie, E | 1 |
| Denis, C | 1 |
| Franques-Rénéric, P | 1 |
| Tignol, J | 1 |
| Auriacombe, M | 1 |
| Lintzeris, N | 1 |
| Mitchell, TB | 1 |
| Bond, A | 1 |
| Nestor, L | 1 |
| Rizzo, F | 1 |
| Tennant, FS | 1 |
| Rawson, RA | 1 |
| Cohen, A | 1 |
| Tarver, A | 1 |
| Clabough, D | 1 |
| Hargreaves, WA | 1 |
| Tyler, J | 1 |
| Weinberg, JA | 1 |
| Sorensen, JL | 1 |
| Benowitz, N | 1 |
| Ryser, PE | 1 |
| Stitzer, ML | 2 |
| Griffiths, RR | 1 |
| McLellan, AT | 1 |
| Grabowski, J | 1 |
| Hawthorne, JW | 1 |
| Pérez de los Cobos, J | 1 |
| Trujols, J | 1 |
| Ribalta, E | 1 |
| Casas, M | 1 |
| Piredda, F | 1 |
| Cugurra, F | 1 |
| Canevari, A | 1 |
| Bigelow, GE | 1 |
| Liebson, I | 1 |
| Burstein, Y | 1 |
| Giardina, PJ | 1 |
| Rausen, AR | 1 |
| Kandall, SR | 2 |
| Siljestrom, K | 1 |
| Peterson, CM | 1 |
| Budd, RD | 1 |
| Walkin, E | 1 |
| Jain, NC | 1 |
| Sneath, TC | 1 |
| Goddard, J | 1 |
| Wilson, GS | 1 |
| Madden, JD | 1 |
| Chappel, JN | 1 |
| Zuspan, F | 1 |
| Gumpel, J | 1 |
| Mejia, A | 1 |
| Davis, R | 1 |
| Raskind, M | 1 |
| Bradford, T | 1 |
| Finnegan, LP | 2 |
| Connaughton, JF | 1 |
| Kron, RE | 2 |
| Emich, JP | 1 |
| Zelson, C | 2 |
| Ramer, CM | 1 |
| Lodge, A | 1 |
| Litt, M | 1 |
| Woody, GE | 1 |
| O'Brien, CP | 1 |
| Greenstein, R | 1 |
| Blinick, G | 1 |
| Wallach, RC | 1 |
| Jerez, E | 1 |
| Ackerman, BD | 1 |
| Koyuncuoğlu, H | 1 |
| Saydam, B | 1 |
| Barattini, M | 1 |
| Fantozzi, R | 1 |
| Masini, E | 1 |
| Mannaioni, PF | 1 |
| Ball, JC | 1 |
| Corty, E | 1 |
| Erdlen, DL | 1 |
| Nurco, DN | 1 |
| Kreuzer, A | 1 |
| Gartner, LM | 1 |
| Glass, L | 1 |
| Rothstein, P | 1 |
| Gould, JB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Randomized Comparative Effectiveness Clinical Trial of Buprenorphine vs. Methadone for the Treatment of Opioid Dependence in Pregnancy.[NCT03098407] | 55 participants (Actual) | Interventional | 2017-04-20 | Completed | |||
| Assessing the Effects of Auricular Acupressure on Newborn Behaviors and Withdrawal Signs in Newborns With Neonatal Abstinence Syndrome: A Pilot Study[NCT03890562] | 12 participants (Actual) | Interventional | 2019-09-04 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for diazepam and Heroin Abuse
| Article | Year |
|---|---|
[Abuse of alcohol and benzodiazepine during substitution therapy in heroin addicts: a review of the literature].
Topics: Adolescent; Adult; Alcoholism; Benzodiazepines; Buprenorphine; Clonazepam; Clorazepate Dipotassium; | 2009 |
[Benzodiazepine withdrawal in subjects on opiate substitution treatment].
Topics: Anticonvulsants; Benzodiazepines; Diazepam; Heroin Dependence; Humans; Methadone; Narcotics; Substan | 2006 |
3 trials available for diazepam and Heroin Abuse
| Article | Year |
|---|---|
Interactions on mixing diazepam with methadone or buprenorphine in maintenance patients.
Topics: Adolescent; Adult; Buprenorphine; Diazepam; Double-Blind Method; Drug Interactions; Female; Heroin D | 2006 |
Cocaine use immediately prior to entry in an inpatient heroin detoxification unit as a predictor of discharges against medical advice.
Topics: Analgesics, Opioid; Analysis of Variance; Antiemetics; Cocaine; Counseling; Dextropropoxyphene; Diaz | 1997 |
The treatment of heroin addicts with dextromethorphan: a double-blind comparison of dextromethorphan with chlorpromazine.
Topics: Adult; Chlorpromazine; Dextromethorphan; Diazepam; Double-Blind Method; Female; Heroin Dependence; H | 1990 |
30 other studies available for diazepam and Heroin Abuse
| Article | Year |
|---|---|
Alleged breaches of "standards of medical care" in a patient overdose death possibly related to chronic opioid analgesic therapy, application of the controlled substances model guidelines: case report.
Topics: Adult; Analgesics, Opioid; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Diazepam; Doxepin; | 2009 |
Unsuspected prenatal opioid exposure: long-term detection by alternative matrices.
Topics: Diazepam; Drug Monitoring; Female; Heroin; Heroin Dependence; Humans; Hypnotics and Sedatives; Infan | 2010 |
Relationship between prescribing and risk of opiate overdose among drug users in and out of maintenance treatment.
Topics: Adult; Alcoholic Intoxication; Benzodiazepines; Causality; Cocaine-Related Disorders; Comorbidity; C | 2004 |
[Intoxication with methadone and benzodiazepines in a morbidly obese patient in the social environment of a heroin addict receiving methadone maintenance therapy].
Topics: Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Blood Gas Analysis; Diazepam; Emergency Me | 2004 |
[The need for psychopharmacologic therapy of drug addicts with acute hepatitis].
Topics: Acute Disease; Diazepam; Drug Therapy, Combination; Hepatitis; Heroin Dependence; Humans; Methadone; | 1984 |
Methadone plasma levels and persistent drug abuse in high dose maintenance patients.
Topics: Alcohol Drinking; Diazepam; Dose-Response Relationship, Drug; Heroin Dependence; Humans; Methadone; | 1984 |
(--)-alpha-Acetylmethadol effects on alcohol and diazepam use, sexual function and cardiac function.
Topics: Adult; Alcohol Drinking; Blood Pressure; Diazepam; Electrocardiography; Heart; Heart Rate; Heroin De | 1983 |
Sex differences in substance abuse: 1976-1979.
Topics: Alcohol Drinking; Diazepam; Female; Heroin Dependence; Humans; Illicit Drugs; Male; Morphine Depende | 1983 |
Diazepam use among methadone maintenance patients: patterns and dosages.
Topics: Adult; Barbiturates; Benzodiazepines; Diazepam; Drug Synergism; Heroin Dependence; Humans; Male; Mar | 1981 |
[Detoxication of heroin addicts in the area of Genoa].
Topics: Adolescent; Adult; Amino Acids; Clonidine; Diazepam; Female; Fructose; Heroin Dependence; Humans; Ma | 1979 |
Reinforcement of drug abstinence: a behavioral approach to drug abuse treatment.
Topics: Adult; Alcoholism; Behavior Therapy; Diazepam; Heroin Dependence; Humans; Methadone; Opioid-Related | 1979 |
Thrombocytosis and increased circulating platelet aggregates in newborn infants of polydrug users.
Topics: Amphetamine; Cocaine; Diazepam; Female; Heroin Dependence; Humans; Infant; Infant, Newborn; Infant, | 1979 |
Frequency of use of diazepam in individuals on probation and in methadone maintenance programs.
Topics: Diazepam; Heroin Dependence; Humans; Illicit Drugs; Methadone; Prisoners; Substance-Related Disorder | 1979 |
Management of neonatal drug withdrawal.
Topics: Diazepam; Heroin Dependence; Humans; Infant, Newborn; Infant, Newborn, Diseases; Methadone; Seizures | 1978 |
Observation and treatment of neonatal narcotic withdrawal.
Topics: Diazepam; Drug Therapy, Combination; Female; Heroin Dependence; Humans; Infant, Newborn; Infant, New | 1977 |
Methylphenidate (ritalin) abuse and methadone maintenance.
Topics: Adult; Amphetamine; Atropa belladonna; Barbiturates; Diazepam; Female; Heroin Dependence; Humans; Ma | 1975 |
Neonatal abstinence syndrome: assessment and management.
Topics: Administration, Oral; Antidiarrheals; Central Nervous System; Diazepam; Digestive System; Female; He | 1975 |
Acute management of neonatal addiction.
Topics: Antidiarrheals; Chlorpromazine; Diazepam; Female; Heroin Dependence; Humans; Infant, Newborn; Infant | 1975 |
Neonatal addiction: a two-year study. Part I. Clinical and developmental characteristics of infants of mothers on methadone maintenance.
Topics: Administration, Oral; Age Factors; Attention; Birth Weight; Child Development; Diazepam; Dose-Respon | 1975 |
Narcotic addiction in the newborn: differences in behavior generated by methadone and heroin.
Topics: Adaptation, Physiological; Diazepam; Female; Heroin Dependence; Humans; Infant, Newborn; Infant, New | 1975 |
Misuse and abuse of diazepam: an increasingly common medical problem.
Topics: Adult; Diazepam; Drug Prescriptions; Heroin Dependence; Humans; Legislation, Drug; Male; Methadone; | 1975 |
Drug addiction in pregnancy and the neonate.
Topics: Alcoholic Intoxication; Birth Weight; Diazepam; Female; Heroin Dependence; Hospitalization; Humans; | 1976 |
[Abuse of licit drugs in heroin addicts].
Topics: Adolescent; Adult; Anti-Anxiety Agents; Diazepam; Female; Flunitrazepam; Heroin Dependence; Humans; | 1987 |
Major patterns of polydrug abuse among heroin addicts.
Topics: Alcoholism; Amphetamines; Barbiturates; Cannabis; Cocaine; Diazepam; Heroin Dependence; Humans; Male | 1986 |
[Surreptitious acquisition of medical prescriptions. Criminologic studies on drugs and deliquency].
Topics: Adolescent; Adult; Central Nervous System Stimulants; Criminology; Deception; Diazepam; Drug and Nar | 1974 |
Infant of the addicted mother.
Topics: Chlorpromazine; Diazepam; Female; Heroin Dependence; Humans; Infant, Newborn; Infant, Newborn, Disea | 1973 |
Treatment of neonatal withdrawal syndrome.
Topics: Chlorpromazine; Diazepam; Heroin Dependence; Humans; Infant, Newborn; Methadone; Opium; Phenobarbita | 1973 |
Late presentation of drug withdrawal symptoms in newborns.
Topics: Birth Weight; Camphor; Diazepam; Female; Gestational Age; Heroin Dependence; Humans; Infant; Infant, | 1974 |
Narcotic withdrawal in the newborn infant.
Topics: Diazepam; Female; Fetus; Heroin Dependence; Humans; Infant, Newborn; Infant, Newborn, Diseases; Mate | 1974 |
Born with a habit. Infants of drug-addicted mothers.
Topics: Abnormalities, Drug-Induced; Adult; Age Factors; Barbiturates; Camphor; Chlorpromazine; Codeine; Dia | 1974 |