diazepam has been researched along with Hepatitis in 10 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Hepatitis: INFLAMMATION of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of 5 mg of diazepam intravenously were assessed in 23 patients with liver disease, 10 of whom had clinical evidence either in the past or at the time of study of hepatic encephalopathy." | 3.65 | Clinical and electroencephalographic assessment of diazepam in liver disease. ( Knill-Jones, RP; Murray-Lyon, IM; Parkes, JD; Williams, R; Young, J, 1971) |
| " The accumulation of DD after multiple dosage could be explained by the fact that it is formed faster from D than it is eliminated." | 2.64 | Disposition of diazepam and its major metabolite desmethyldiazepam in patients with liver disease. ( Antonin, KH; Bieck, PR; Brügel, H; Klotz, U, 1977) |
| "Diazepam-treated patients became calm in one half the time needed to calm patients with paraldehyde." | 2.64 | Diazepam and paraldehyde for treatment of severe delirium tremens. A controlled trial. ( Johnson, AD; Maddrey, WL; Thompson, WL, 1975) |
| " Despite the profound prolongation of t 1/2 (theta) with age, the constancy of diazepam clearance indicates that drug plasma concentrations will not accumulate any more in the old than the young, and chronic dosage more in the old than the young, and chronic dosage modifications based on pharmacokinetic considerations are unnecessary." | 1.25 | The effects of age and liver disease on the disposition and elimination of diazepam in adult man. ( Avant, GR; Hoyumpa, A; Klotz, U; Schenker, S; Wilkinson, GR, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| INVERNIZZI, G | 1 |
| COOK, GC | 1 |
| SHERLOCK, S | 1 |
| Rizzo, F | 1 |
| Luyckx, A | 1 |
| Van Cauwenberge, H | 1 |
| Hoyumpa, AM | 2 |
| Schenker, S | 2 |
| Wilkinson, GR | 2 |
| Klotz, U | 2 |
| Antonin, KH | 1 |
| Brügel, H | 1 |
| Bieck, PR | 1 |
| Thompson, WL | 1 |
| Johnson, AD | 1 |
| Maddrey, WL | 1 |
| Avant, GR | 1 |
| Hoyumpa, A | 1 |
| Murray-Lyon, IM | 1 |
| Young, J | 1 |
| Parkes, JD | 1 |
| Knill-Jones, RP | 1 |
| Williams, R | 1 |
1 review available for diazepam and Hepatitis
| Article | Year |
|---|---|
The effect of parenchymal liver disease on the disposition and elimination of sedatives and analgesics.
Topics: Analgesics; Anti-Anxiety Agents; Barbiturates; Diazepam; Half-Life; Hepatitis; Humans; Hypnotics and | 1975 |
2 trials available for diazepam and Hepatitis
| Article | Year |
|---|---|
Disposition of diazepam and its major metabolite desmethyldiazepam in patients with liver disease.
Topics: Adult; Biological Availability; Biotransformation; Clinical Trials as Topic; Diazepam; Half-Life; He | 1977 |
Diazepam and paraldehyde for treatment of severe delirium tremens. A controlled trial.
Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Clinical Trials as Topic; Diazepam; Female; Hepatiti | 1975 |
7 other studies available for diazepam and Hepatitis
| Article | Year |
|---|---|
[OBSERVATIONS ON THE USE OF PHENYLPYRROLIDINOPENTANE AS AN ANTIASTHENIC AGENT IN TREATMENT WITH PSYCHOPHARMACOLOGICAL DRUGS].
Topics: Amitriptyline; Anxiety; Anxiety Disorders; Asthenia; Bipolar Disorder; Chemical and Drug Induced Liv | 1964 |
JAUNDICE AND ITS RELATION TO THERAPEUTIC AGENTS.
Topics: Alkaline Phosphatase; Antidepressive Agents; Aspartate Aminotransferases; Bilirubin; Chemical and Dr | 1965 |
[The need for psychopharmacologic therapy of drug addicts with acute hepatitis].
Topics: Acute Disease; Diazepam; Drug Therapy, Combination; Hepatitis; Heroin Dependence; Humans; Methadone; | 1984 |
[Therapeutic news of 1975].
Topics: Bismuth; Cardiovascular Diseases; Diazepam; Drug Therapy; Endocrine System Diseases; Gastrointestina | 1976 |
Disposition and elimination of minor tranquilizers in the aged and in patients with liver disease.
Topics: Aged; Aging; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Hepatitis; Humans; Liver Cirrhosis; Li | 1978 |
The effects of age and liver disease on the disposition and elimination of diazepam in adult man.
Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Aging; Alcoholism; Animals; Diazepam; Fe | 1975 |
Clinical and electroencephalographic assessment of diazepam in liver disease.
Topics: Alcoholism; Budd-Chiari Syndrome; Cholestasis; Chronic Disease; Consciousness; Diazepam; Electroence | 1971 |