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diazepam and Hepatic Failure

diazepam has been researched along with Hepatic Failure in 4 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Research Excerpts

ExcerptRelevanceReference
"A 2-year-old castrated male domestic shorthair cat developed acute hepatic failure following oral diazepam administration for behavioral problems."7.78Successful treatment of hepatic failure secondary to diazepam administration in a cat. ( Park, FM, 2012)
" Its usefulness in a large-scale culture with a circulatory bioreactor in vitro and in dog models of ischemic hepatic failure with acute diazepam (DZP, a substrate of CYP3A4) overdosage was further examined."7.73The bioreactor with CYP3A4- and glutamine synthetase-introduced HepG2 cells: treatment of hepatic failure dog with diazepam overdosage. ( Enosawa, S; Fujimura, A; Matsumura, T; Nagai, H; Omasa, T; Sata, N; Tsuruoka, S; Wang, N; Yamamoto, H, 2005)
"A 2-year-old castrated male domestic shorthair cat developed acute hepatic failure following oral diazepam administration for behavioral problems."3.78Successful treatment of hepatic failure secondary to diazepam administration in a cat. ( Park, FM, 2012)
" Its usefulness in a large-scale culture with a circulatory bioreactor in vitro and in dog models of ischemic hepatic failure with acute diazepam (DZP, a substrate of CYP3A4) overdosage was further examined."3.73The bioreactor with CYP3A4- and glutamine synthetase-introduced HepG2 cells: treatment of hepatic failure dog with diazepam overdosage. ( Enosawa, S; Fujimura, A; Matsumura, T; Nagai, H; Omasa, T; Sata, N; Tsuruoka, S; Wang, N; Yamamoto, H, 2005)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Drexler, K1
Baustian, C1
Richter, G1
Ludwig, J1
Ramlow, W1
Mitzner, S1
Park, FM1
Wang, N1
Tsuruoka, S1
Yamamoto, H1
Enosawa, S1
Omasa, T1
Sata, N1
Matsumura, T1
Nagai, H1
Fujimura, A1
Zeneroli, ML1
Venturini, I1
Corsi, L1
Avallone, R1
Farina, F1
Ardizzone, G1
Centanaro, M1
Arrigo, A1
Schreier, P1
Kleinschnitz, M1
Baraldi, M1

Other Studies

4 other studies available for diazepam and Hepatic Failure

ArticleYear
Albumin dialysis molecular adsorbents recirculating system: impact of dialysate albumin concentration on detoxification efficacy.
    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2009, Volume: 13, Issue:5

    Topics: Bilirubin; Chenodeoxycholic Acid; Creatinine; Dialysis; Dialysis Solutions; Diazepam; Humans; Liver

2009
Successful treatment of hepatic failure secondary to diazepam administration in a cat.
    Journal of feline medicine and surgery, 2012, Volume: 14, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Cat Diseases; Cats; Diagnosis, Differential; Diazepa

2012
The bioreactor with CYP3A4- and glutamine synthetase-introduced HepG2 cells: treatment of hepatic failure dog with diazepam overdosage.
    Artificial organs, 2005, Volume: 29, Issue:8

    Topics: Animals; Bioreactors; Cell Line; Cricetinae; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System;

2005
Benzodiazepine-like compounds in the plasma of patients with fulminant hepatic failure.
    Scandinavian journal of gastroenterology, 1998, Volume: 33, Issue:3

    Topics: Adult; Benzodiazepines; Chromatography, High Pressure Liquid; Diazepam; Female; Hepatic Encephalopat

1998