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diazepam and Fasciculation

diazepam has been researched along with Fasciculation in 12 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Fasciculation: Involuntary contraction of the muscle fibers innervated by a motor unit. Fasciculations may be visualized as a muscle twitch or dimpling under the skin, but usually do not generate sufficient force to move a limb. They may represent a benign condition or occur as a manifestation of MOTOR NEURON DISEASE or PERIPHERAL NERVOUS SYSTEM DISEASES. (Adams et al., Principles of Neurology, 6th ed, p1294)

Research Excerpts

ExcerptRelevanceReference
"Succinylcholine is used during induction of anesthesia, and it may induce fasciculations."9.12Lidocaine or diazepam can decrease fasciculation induced by succinylcholine during induction of anesthesia. ( Hassani, M; Sahraian, MA, 2006)
"To determine the effectiveness of diazepam pretreatment in preventing succinylcholine-induced fasciculations, 61 surgical patients were randomly allocated into three groups receiving either diazepam (0."9.05Does diazepam pretreatment prevent succinylcholine-induced fasciculations?--a double-blind comparison of diazepam and tubocurarine pretreatments. ( Erkola, O; Salmenperä, M; Tammisto, T, 1980)
"To determine the effectiveness of diazepam pretreatment in preventing succinylcholine (SCh)-induced fasciculations and body pains, 587 patients were randomly allocated to six groups."7.67Diazepam does not prevent succinylcholine-induced fasciculations and myalgia. A comparative evaluation of the effect of diazepam and d-tubocurarine pretreatments. ( Manchikanti, L, 1984)
"The efficacy of diazepam in attenuation of succinylcholine-induced muscle fasciculations was studied in the dog."7.66Effect of diazepam pretreatment on succinylcholine-induced muscle fasciculation in the dog. ( Crimi, AJ; Raffe, MR; Ruff, J, 1982)
"To determine the effectiveness of diazepam pretreatment in preventing succinylcholine-induced fasciculations, 61 surgical patients were randomly allocated into three groups receiving either diazepam (0."5.05Does diazepam pretreatment prevent succinylcholine-induced fasciculations?--a double-blind comparison of diazepam and tubocurarine pretreatments. ( Erkola, O; Salmenperä, M; Tammisto, T, 1980)
"To determine the effectiveness of diazepam pretreatment in preventing succinylcholine (SCh)-induced fasciculations and body pains, 587 patients were randomly allocated to six groups."3.67Diazepam does not prevent succinylcholine-induced fasciculations and myalgia. A comparative evaluation of the effect of diazepam and d-tubocurarine pretreatments. ( Manchikanti, L, 1984)
"A patient developed severe anxiety, moodswing, depression, and thinking disorder 24 hours after abruptly stopping oxazepam, of which he had taken 30 mg 3 times a day for two months, for anxiety and panic attacks."3.66Abstinence syndrome from therapeutic doses of oxazepam. ( Kulik, AV; Wilbur, R, 1983)
"The efficacy of diazepam in attenuation of succinylcholine-induced muscle fasciculations was studied in the dog."3.66Effect of diazepam pretreatment on succinylcholine-induced muscle fasciculation in the dog. ( Crimi, AJ; Raffe, MR; Ruff, J, 1982)
"All four of the reviewed cases with myokymia of the shoulders were intubated and none without it were intubated."1.35Fasciculations after rattlesnake envenomations: a retrospective statewide poison control system study. ( Cantrell, FL; Vohra, R; Williams, SR, 2008)
"Diazepam pretreatment prevented muscle fasciculations, increases in serum potassium (K+) and creatinine phosphokinase (CPK) levels, increased heart rate and arterial pressure, and postoperative myalgia associated with SCh administration."1.26Diazepam prevents some adverse effects of succinylcholine. ( Fahmy, NR; Lappas, DG; Malek, NS, 1979)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19909 (75.00)18.7374
1990's1 (8.33)18.2507
2000's2 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hassani, M1
Sahraian, MA1
Vohra, R1
Cantrell, FL1
Williams, SR1
Manchikanti, L1
Wilbur, R1
Kulik, AV1
Erkola, O1
Salmenperä, M1
Tammisto, T1
Raffe, MR1
Crimi, AJ1
Ruff, J1
Fahmy, NR1
Malek, NS1
Lappas, DG1
Koley, KC1
Roy, AK1
Sinha, G1
Vojtek, P1
Clemensen, SE1
Christensen, KJ1
Olesen, AS1
Paul, AK1
Owen-Falkenberg, A1

Trials

3 trials available for diazepam and Fasciculation

ArticleYear
Lidocaine or diazepam can decrease fasciculation induced by succinylcholine during induction of anesthesia.
    Middle East journal of anaesthesiology, 2006, Volume: 18, Issue:5

    Topics: Adult; Anesthesia; Anesthetics, Intravenous; Anesthetics, Local; Blood Pressure; Diazepam; Elective

2006
Does diazepam pretreatment prevent succinylcholine-induced fasciculations?--a double-blind comparison of diazepam and tubocurarine pretreatments.
    Anesthesia and analgesia, 1980, Volume: 59, Issue:12

    Topics: Clinical Trials as Topic; Diazepam; Double-Blind Method; Fasciculation; Humans; Movement Disorders;

1980
[Does diazepam prevent fasciculation and myalgias caused by suxamethonium? A double-blind study].
    Ugeskrift for laeger, 1987, Feb-02, Volume: 149, Issue:6

    Topics: Clinical Trials as Topic; Diazepam; Double-Blind Method; Fasciculation; Female; Gallamine Triethiodi

1987

Other Studies

9 other studies available for diazepam and Fasciculation

ArticleYear
Fasciculations after rattlesnake envenomations: a retrospective statewide poison control system study.
    Clinical toxicology (Philadelphia, Pa.), 2008, Volume: 46, Issue:2

    Topics: Adolescent; Adult; Animals; Antivenins; Anxiety; California; Child; Child, Preschool; Crotalus; Data

2008
Diazepam does not prevent succinylcholine-induced fasciculations and myalgia. A comparative evaluation of the effect of diazepam and d-tubocurarine pretreatments.
    Acta anaesthesiologica Scandinavica, 1984, Volume: 28, Issue:5

    Topics: Anesthesia, General; Diazepam; Fasciculation; Humans; Muscular Diseases; Neurologic Manifestations;

1984
Abstinence syndrome from therapeutic doses of oxazepam.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1983, Volume: 28, Issue:4

    Topics: Adult; Anxiety; Depression; Depressive Disorder; Diazepam; Fasciculation; Fear; Humans; Male; Oxazep

1983
Effect of diazepam pretreatment on succinylcholine-induced muscle fasciculation in the dog.
    American journal of veterinary research, 1982, Volume: 43, Issue:3

    Topics: Animals; Diazepam; Dog Diseases; Dogs; Fasciculation; Female; Male; Neurologic Manifestations; Potas

1982
Diazepam prevents some adverse effects of succinylcholine.
    Clinical pharmacology and therapeutics, 1979, Volume: 26, Issue:3

    Topics: Adolescent; Adult; Anesthesia; Creatine Kinase; Diazepam; Fasciculation; Female; Humans; Intubation,

1979
Neuromyotonia.
    Journal of the Indian Medical Association, 1992, Volume: 90, Issue:5

    Topics: Adult; Diazepam; Fasciculation; Humans; Male; Myotonia; Quinine

1992
[Prevention of myalgia after intravenous administration of succinylcholine iodide].
    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti, 1988, Volume: 67, Issue:2

    Topics: Anesthesia, General; Diazepam; Fasciculation; Humans; Injections, Intravenous; Muscles; Pain; Succin

1988
Influence of diazepam on the effects of suxamethonium.
    Journal of the Indian Medical Association, 1986, Volume: 84, Issue:9

    Topics: Adolescent; Adult; Anesthesia, Intravenous; Diazepam; Fasciculation; Female; Humans; Male; Middle Ag

1986
[Does diazepam prevent against suxamethonium-induced fasciculation and myalgia?].
    Ugeskrift for laeger, 1987, Mar-02, Volume: 149, Issue:10

    Topics: Diazepam; Fasciculation; Humans; Muscular Diseases; Pain; Succinylcholine

1987