diazepam has been researched along with Epilepsy, Tonic-Clonic in 109 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Epilepsy, Tonic-Clonic: A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
| Excerpt | Relevance | Reference |
|---|---|---|
| " We aimed to find out whether there are differences in efficacy and adverse events between buccal administration of liquid midazolam and rectal administration of liquid diazepam in the acute treatment of seizures." | 9.09 | Buccal midazolam and rectal diazepam for treatment of prolonged seizures in childhood and adolescence: a randomised trial. ( Besag, FM; Neville, BG; Scott, RC, 1999) |
| " We aimed to find out whether there are differences in efficacy and adverse events between buccal administration of liquid midazolam and rectal administration of liquid diazepam in the acute treatment of seizures." | 5.09 | Buccal midazolam and rectal diazepam for treatment of prolonged seizures in childhood and adolescence: a randomised trial. ( Besag, FM; Neville, BG; Scott, RC, 1999) |
| "To review the evidence comparing diazepam, lorazepam, phenobarbitone, phenytoin and paraldehyde in treating acute tonic-clonic convulsions and convulsive status epilepticus in children." | 4.81 | Drug management for acute tonic-clonic convulsions including convulsive status epilepticus in children. ( Appleton, R; Martland, T; Phillips, B, 2002) |
| "During her first pregnancy, a 37-year-old woman with idiopathic generalised epilepsy that was adequately controlled with lamotrigine experienced a series of epileptic seizures following an elective caesarean section." | 3.73 | [Epileptic seizures during childbirth in a patient with idiopathic generalised epilepsy]. ( Bloem, BR; Renier, WO; Voermans, NC; Zwarts, MJ, 2005) |
| " This report describes a near-hanging episode in a patient who subsequently had status epilepticus requiring 40 mg of diazepam and 1,200 mg of phenytoin for control in the prehospital and emergency department stabilization period." | 3.70 | Hanging-induced status epilepticus. ( Pesola, GR; Westfal, RE, 1999) |
| "Diazepam median Tmax was 45 min." | 2.79 | Dosing feasibility and tolerability of intranasal diazepam in adults with epilepsy. ( Bream, G; Carrazana, EJ; Haas, KF; Henney, HR; Krauss, G; Rabinowicz, AL; Seif Eddeine, H; Sperling, MR; Squillacote, D, 2014) |
| " Subsequent replacement of hypertonic saline with normal saline and salt tabs in combination with phenytoin allowed gradual correction of serum sodium without any subsequent seizures or neurological complications." | 2.41 | Therapy with hypertonic saline in combination with anti-convulsants for hyponatremia-induced seizure: a case report and review of the literature. ( Tokeshi, J; Youn, KS, 2002) |
| "Drug treatment of status epilepticus is reviewed." | 2.36 | Drug therapy reviews: drug therapy of status epilepticus. ( Browne, TR, 1978) |
| "Clonazepam is a new benzodiazepine anticonvulsant recently approved by the Food and Drug Administration for the treatment of typical absence, infantile myoclonic, atypical absence, myoclonic, and akinetic seizures." | 2.35 | Clonazepam. A review of a new anticonvulsant drug. ( Browne, TR, 1976) |
| "Here, we report a typical case of 'senile chorea' associated with PAPS, thus expanding the potential underlying etiologies and further narrowing the window of primary 'senile chorea'." | 1.35 | Narrowing the window for 'senile chorea': a case with primary antiphospholipid syndrome. ( Apale, P; Appollonio, I; Capra, M; Ferrarese, C; Frigo, M; Galbussera, A; Gelosa, G; Perego, R; Tremolizzo, L, 2009) |
| "Orphenadrine is an anticholinergic drug used mainly in the treatment of Parkinson's disease." | 1.30 | Orphenadrine poisoning in a child: clinical and analytical data. ( Maes, V; Mertens, K; Ramet, J; Van Herreweghe, I, 1999) |
| "After baseline recordings, seizures were induced with a pentylenetetrazol (PTZ) bolus and a 20 min infusion (5-6 mg/kg/min)." | 1.29 | Respiratory drive during status epilepticus and its treatment: comparison of diazepam and lorazepam. ( Fordyce, WE; Terndrup, TE, 1995) |
| "Physical dependence was produced in the rat by exposure to continuous release of diazepam from silastic capsule implants (recrystallized diazepam) or by dosing through a gastric fistula." | 1.29 | Precipitated abstinence in the diazepam-dependent rat. ( Martin, WR; Sloan, JW; Wala, EP, 1993) |
| "A series of 5 generalized tonic-clonic seizures within 30 min was induced by repeated transauricular electrical stimulation in mice." | 1.28 | Intravenous valproate: onset and duration of anticonvulsant activity against a series of electroconvulsions in comparison with diazepam and phenytoin. ( Hönack, D; Löscher, W, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 72 (66.06) | 18.7374 |
| 1990's | 18 (16.51) | 18.2507 |
| 2000's | 9 (8.26) | 29.6817 |
| 2010's | 10 (9.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McTague, A | 1 |
| Martland, T | 2 |
| Appleton, R | 2 |
| Belcher, SF | 1 |
| Morton, TR | 1 |
| Feng, R | 1 |
| Che, X | 1 |
| Hu, J | 1 |
| Pan, L | 1 |
| Cui, D | 1 |
| Yang, L | 1 |
| Godoy, LD | 1 |
| Liberato, JL | 1 |
| da Silva Junior, PI | 1 |
| dos Santos, WF | 1 |
| Sperling, MR | 1 |
| Haas, KF | 1 |
| Krauss, G | 1 |
| Seif Eddeine, H | 1 |
| Henney, HR | 1 |
| Rabinowicz, AL | 1 |
| Bream, G | 1 |
| Squillacote, D | 1 |
| Carrazana, EJ | 1 |
| Serdyuk, SE | 1 |
| Gmiro, VE | 1 |
| Shakarjian, MP | 1 |
| Ali, MS | 1 |
| Velíšková, J | 1 |
| Stanton, PK | 1 |
| Heck, DE | 1 |
| Velíšek, L | 1 |
| Gelosa, G | 1 |
| Tremolizzo, L | 1 |
| Galbussera, A | 1 |
| Perego, R | 1 |
| Capra, M | 1 |
| Frigo, M | 1 |
| Apale, P | 1 |
| Ferrarese, C | 1 |
| Appollonio, I | 1 |
| Ben-Cherif, W | 1 |
| Gharbi, R | 1 |
| Sebai, H | 1 |
| Dridi, D | 1 |
| Boughattas, NA | 1 |
| Ben-Attia, M | 1 |
| Yanase, M | 1 |
| Kaido, T | 1 |
| Yamada, M | 1 |
| Watanabe, M | 1 |
| Finke, MD | 1 |
| Meola, SD | 1 |
| Mazzaferro, EM | 1 |
| Phillips, B | 1 |
| Youn, KS | 1 |
| Tokeshi, J | 1 |
| Toomes, M | 1 |
| Maleck, WH | 1 |
| Koetter, KP | 1 |
| Petroianu, GA | 1 |
| BARSA, JA | 1 |
| SAUNDERS, JC | 1 |
| BARTEN, HH | 1 |
| Ozucelik, DN | 1 |
| Karcioglu, O | 1 |
| Topacoglu, H | 1 |
| Fowler, JR | 1 |
| Voermans, NC | 1 |
| Zwarts, MJ | 1 |
| Renier, WO | 1 |
| Bloem, BR | 1 |
| Compton, R | 1 |
| Spiller, HA | 1 |
| Bosse, GM | 1 |
| Parisi, P | 1 |
| Kasteleijn-Nolst Trenité, DG | 1 |
| Piccioli, M | 1 |
| Pelliccia, A | 1 |
| Luchetti, A | 1 |
| Buttinelli, C | 1 |
| Villa, MP | 1 |
| Jonsson, S | 1 |
| O'Meara, M | 1 |
| Young, JB | 1 |
| Browne, TR | 4 |
| Dean, LS | 1 |
| Brown, JW | 1 |
| Terndrup, TE | 1 |
| Fordyce, WE | 1 |
| Mizoguchi, H | 1 |
| Suzuki, T | 1 |
| Misawa, M | 1 |
| Brodtkorb, E | 1 |
| Sand, T | 1 |
| Kristiansen, A | 1 |
| Torbergsen, T | 1 |
| Robertson, M | 1 |
| Bell, J | 1 |
| Storrow, AB | 1 |
| Davidson, DL | 1 |
| Martin, WR | 1 |
| Sloan, JW | 1 |
| Wala, EP | 1 |
| Altrock, G | 1 |
| Lange, A | 1 |
| Münster, P | 1 |
| Sagduyu, A | 1 |
| Tarlaci, S | 1 |
| Sirin, H | 1 |
| Schweiger, A | 1 |
| Pesola, GR | 1 |
| Westfal, RE | 1 |
| Scott, RC | 1 |
| Besag, FM | 1 |
| Neville, BG | 1 |
| Van Herreweghe, I | 1 |
| Mertens, K | 1 |
| Maes, V | 1 |
| Ramet, J | 1 |
| Urbanska, EM | 1 |
| Tomczyk, T | 1 |
| Haberek, G | 1 |
| Pilip, S | 1 |
| Matyska, J | 1 |
| Turski, WA | 1 |
| Kleinrok, Z | 1 |
| Czuczwar, SJ | 1 |
| Butler, J | 1 |
| Lewis, M | 1 |
| de Bard, ML | 1 |
| Livingston, S | 1 |
| Pruce, I | 1 |
| Pauli, LL | 1 |
| Rifkin, A | 2 |
| Klein, DF | 2 |
| Quitkin, F | 2 |
| Englander, RN | 1 |
| Johnson, RN | 1 |
| Brickley, JJ | 1 |
| Hanna, GR | 1 |
| Vyas, I | 1 |
| Carney, MW | 1 |
| Gibberd, FB | 1 |
| Wallace, SJ | 1 |
| Khalid, MS | 1 |
| Schulz, H | 2 |
| Mordel, A | 1 |
| Winkler, E | 1 |
| Almog, S | 1 |
| Tirosh, M | 1 |
| Ezra, D | 1 |
| Hönack, D | 1 |
| Löscher, W | 1 |
| Piepho, R | 1 |
| Whelton, A | 1 |
| Mayor, G | 1 |
| Neu, H | 1 |
| Laddu, A | 1 |
| Enginar, N | 1 |
| Eroğlu, L | 1 |
| Gombos, GM | 1 |
| Lieberman, RM | 1 |
| van Sweden, B | 1 |
| Medici, V | 1 |
| Roth, F | 1 |
| Keller, HP | 1 |
| Parish, RA | 1 |
| Brownstein, D | 1 |
| Steidl, L | 1 |
| Tolde, I | 1 |
| Svomová, V | 1 |
| Falconer, MA | 1 |
| Davidson, S | 1 |
| Parsonage, M | 1 |
| Pomina, AC | 1 |
| Tarlau, M | 1 |
| Berman, AJ | 1 |
| Dalby, MA | 1 |
| Leonidas, JC | 1 |
| Brill, PW | 1 |
| Waldman, N | 1 |
| Greenblatt, DJ | 1 |
| Koch-Weser, J | 1 |
| Penry, JK | 1 |
| Ferngren, HG | 1 |
| Peterson, DI | 1 |
| Zweig, RW | 1 |
| Ouellette, EM | 1 |
| Manhire, AR | 1 |
| Espir, M | 1 |
| Nerenz, K | 1 |
| Saper, JR | 1 |
| Lossing, JH | 1 |
| Jezierska, K | 1 |
| Nawrocka, I | 1 |
| Müller, K | 1 |
| Kohlheb, O | 1 |
| Hambert, O | 1 |
| Petersén, I | 1 |
| Millichap, JG | 1 |
| Hagberg, B | 1 |
| Hansson, O | 1 |
| Hooshmand, H | 1 |
| Suter, CG | 1 |
| Levine, AM | 1 |
| Pickett, LK | 1 |
| Touloukian, RJ | 1 |
| Wilson, J | 1 |
| Ritter, G | 1 |
| Mayer, PP | 1 |
| Trolle, E | 1 |
| Lalji, D | 1 |
| Hosking, CS | 1 |
| Sutherland, JM | 1 |
| Prensky, AL | 1 |
| Raff, MC | 1 |
| Moore, MJ | 1 |
| Schwab, RS | 1 |
| Parsonage, MJ | 1 |
| Norris, JW | 1 |
| Bamberger, P | 1 |
| Matthes, A | 1 |
| Miribel, J | 1 |
| Marinier, R | 1 |
| Sawyer, GT | 1 |
| Webster, DD | 1 |
| Schut, LJ | 1 |
| Henriksen, PB | 1 |
| Doose, H | 1 |
| Kaeser, HE | 1 |
| Scharfetter, C | 1 |
| Schmoigl, S | 1 |
| Bell, DS | 1 |
| Bowe, J | 1 |
| Sinha, SN | 1 |
| Barbeau, A | 1 |
| Halász, P | 1 |
| Velok, G | 1 |
| Hidasi, J | 1 |
| Boczán, G | 1 |
| Elian, M | 1 |
| Niedermeyer, E | 2 |
| Degen, R | 1 |
| Geller, M | 1 |
| Christoff, N | 1 |
| Dowzenko, A | 1 |
| Huber, Z | 1 |
| Zieliński, JJ | 1 |
| Borkowska, Z | 1 |
| Mazurkowa, K | 1 |
| Wojakowski, A | 1 |
| Weinmann, HM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intranasal Midazolam Versus Rectal Diazepam for the Home Treatment of Seizure Activity in Pediatric Patients With Epilepsy[NCT00326612] | Phase 2 | 358 participants (Actual) | Interventional | 2006-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Length of seizure. (NCT00326612)
Timeframe: 24 hours
| Intervention | Minutes (Median) |
|---|---|
| Intranasal Midazolam | 3.0 |
| Rectal Diazepam | 4.3 |
(NCT00326612)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Intranasal Midazolam | 21 |
| Rectal Diazepam | 17 |
(NCT00326612)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Intranasal Midazolam | 4 |
| Rectal Diazepam | 3 |
(NCT00326612)
Timeframe: 12 hours
| Intervention | participants (Number) |
|---|---|
| Intranasal Midazolam | 1 |
| Rectal Diazepam | 1 |
(NCT00326612)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Intranasal Midazolam | 5 |
| Rectal Diazepam | 5 |
Respiratory depression was defined as intubation at Emergency Department discharge. (NCT00326612)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Intranasal Midazolam | 1 |
| Rectal Diazepam | 0 |
Respiratory depression was defined as requiring oxygen at discharge from the Emergency Department. (NCT00326612)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Intranasal Midazolam | 3 |
| Rectal Diazepam | 1 |
10 reviews available for diazepam and Epilepsy, Tonic-Clonic
| Article | Year |
|---|---|
Drug management for acute tonic-clonic convulsions including convulsive status epilepticus in children.
Topics: Administration, Inhalation; Administration, Oral; Administration, Rectal; Anticonvulsants; Child; Di | 2018 |
Tutu toxicity: three case reports of Coriaria arborea ingestion, review of literature and recommendations for management.
Topics: Adult; Anticonvulsants; Diazepam; Epilepsy, Tonic-Clonic; Female; Fruit; Humans; Male; Nausea; Picro | 2013 |
Malformations of cortical development with good clinical outcome: a case report and review of literature.
Topics: Adult; Anticonvulsants; Diazepam; Electroencephalography; Epilepsy, Tonic-Clonic; Humans; Magnetic R | 2012 |
Drug management for acute tonic-clonic convulsions including convulsive status epilepticus in children.
Topics: Administration, Rectal; Anticonvulsants; Child; Diazepam; Epilepsy, Tonic-Clonic; Humans; Injections | 2002 |
Therapy with hypertonic saline in combination with anti-convulsants for hyponatremia-induced seizure: a case report and review of the literature.
Topics: Aged; Anticonvulsants; Diazepam; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Female; Humans; | 2002 |
Bupropion overdose and seizure.
Topics: Adolescent; Bupropion; Charcoal; Diazepam; Drug Overdose; Electrocardiography; Emergency Service, Ho | 1994 |
Drug therapy reviews: drug therapy of status epilepticus.
Topics: Anesthesia, General; Diazepam; Epilepsies, Partial; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epil | 1978 |
Clonazepam. A review of a new anticonvulsant drug.
Topics: Adult; Benzodiazepinones; Brain; Chemical Phenomena; Chemistry; Child; Clonazepam; Diazepam; Drug To | 1976 |
Benzodiazepines in the treatment of epilepsy. A review.
Topics: Adult; Animals; Anticonvulsants; Chlordiazepoxide; Diazepam; Disease Models, Animal; Eclampsia; Elec | 1973 |
The child who convulses with fever.
Topics: Age Factors; Analgesics; Brain Injuries; Central Nervous System Diseases; Child; Child Behavior; Chi | 1974 |
5 trials available for diazepam and Epilepsy, Tonic-Clonic
| Article | Year |
|---|---|
Dosing feasibility and tolerability of intranasal diazepam in adults with epilepsy.
Topics: Administration, Intranasal; Adolescent; Adult; Aged; Anticonvulsants; Diazepam; Epilepsy, Tonic-Clon | 2014 |
Buccal midazolam and rectal diazepam for treatment of prolonged seizures in childhood and adolescence: a randomised trial.
Topics: Administration, Buccal; Administration, Rectal; Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsa | 1999 |
Diazepam ("Valium") in the control of status epilepticus.
Topics: Child; Child, Preschool; Clinical Trials as Topic; Diazepam; Drug Synergism; Epilepsy, Tonic-Clonic; | 1967 |
Acute treatment of epileptic seizures with diazepamum (Valium).
Topics: Acute Disease; Adolescent; Adult; Aged; Aphasia; Clinical Trials as Topic; Diazepam; Epilepsy; Epile | 1967 |
[Intravenous diazepam (Valium) in the treatment of mal epileptic states. A double blind study].
Topics: Adult; Aged; Clinical Trials as Topic; Diazepam; Electroencephalography; Epilepsy, Absence; Epilepsy | 1968 |
94 other studies available for diazepam and Epilepsy, Tonic-Clonic
| Article | Year |
|---|---|
Surgical treatment of recurrent torcular meningiomas: case report and review of the literature.
Topics: Angiography, Digital Subtraction; Anticonvulsants; Contrast Media; Craniotomy; Diazepam; Epilepsy, T | 2013 |
Mygalin: a new anticonvulsant polyamine in acute seizure model and neuroethological schedule.
Topics: Acute Disease; Animals; Anticonvulsants; Cognition; Diazepam; Dizocilpine Maleate; Drug Evaluation, | 2013 |
Phenylephrine potentiates the anticonvulsant effect and neutralizes the sedative effect of diazepam in rats upon combined intragastric administration.
Topics: Animals; Anticonvulsants; Diazepam; Dose-Response Relationship, Drug; Drug Combinations; Drug Evalua | 2014 |
Combined diazepam and MK-801 therapy provides synergistic protection from tetramethylenedisulfotetramine-induced tonic-clonic seizures and lethality in mice.
Topics: Animals; Anticonvulsants; Brain Waves; Bridged-Ring Compounds; Central Nervous System; Diazepam; Dis | 2015 |
Narrowing the window for 'senile chorea': a case with primary antiphospholipid syndrome.
Topics: Age of Onset; Aged; Anti-Dyskinesia Agents; Antibodies, Antiphospholipid; Anticonvulsants; Antiphosp | 2009 |
Neuropharmacological screening of two 1,5-benzodiazepine compounds in mice.
Topics: Animals; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Benzopyrans; Diazepam; Dose-Response R | 2010 |
Ascending tonic-clonic seizure syndrome in a dog following inadvertent intrathecal use of ionic contrast agent.
Topics: Animals; Anticonvulsants; Contrast Media; Diatrizoate; Diazepam; Dog Diseases; Dogs; Epilepsy, Tonic | 2012 |
Out-of-hospital management of benzodiazepine-resistant status epilepticus in a child with Wolf-Hirschhorn syndrome.
Topics: Abnormalities, Multiple; Anticonvulsants; Apnea; Child; Chromosome Deletion; Chromosomes, Human, Pai | 2003 |
COMPARATIVE STUDY OF CHLORDIAZEPOXIDE AND DIAZEPAM.
Topics: Cerebral Palsy; Chlordiazepoxide; Diazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Int | 1964 |
TOXIC PSYCHOSIS WITH TRANSIENT DYSMNESTIC SYNDROME FOLLOWING WITHDRAWAL FROM VALIUM.
Topics: Chlorpromazine; Diazepam; Epilepsy; Epilepsy, Tonic-Clonic; Hallucinations; Humans; Memory; Psychose | 1965 |
Toxicity following unintentional DDT ingestion.
Topics: Acidosis; Acute Kidney Injury; Adolescent; Anticonvulsants; Bicarbonates; Buffers; Critical Care; DD | 2004 |
[Epileptic seizures during childbirth in a patient with idiopathic generalised epilepsy].
Topics: Adult; Anticonvulsants; Cesarean Section; Clonazepam; Diazepam; Epilepsy; Epilepsy, Generalized; Epi | 2005 |
Fatal fluoxetine ingestion with postmortem blood concentrations.
Topics: Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Bradycardia; Child, Preschool; Dia | 2005 |
A case with atypical childhood occipital epilepsy "Gastaut type": an ictal migraine manifestation with a good response to intravenous diazepam.
Topics: Adolescent; Anticonvulsants; Comorbidity; Diazepam; Electroencephalography; Epilepsies, Partial; Epi | 2007 |
Acute cocaine poisoning. Importance of treating seizures and acidosis.
Topics: Acidosis; Acute Disease; Adult; Bicarbonates; Cocaine; Diazepam; Epilepsy, Tonic-Clonic; Foreign Bod | 1983 |
Therapy of status epilepticus.
Topics: Anticonvulsants; Diazepam; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Humans; Lorazepam; Paraldehy | 1982 |
Massive theophylline overdose. Survival without hemoperfusion.
Topics: Bronchodilator Agents; Choline; Diazepam; Epilepsy, Tonic-Clonic; Female; Hemoperfusion; Humans; Mid | 1982 |
Respiratory drive during status epilepticus and its treatment: comparison of diazepam and lorazepam.
Topics: Animals; Diazepam; Disease Models, Animal; Epilepsy, Tonic-Clonic; Hydrogen-Ion Concentration; Loraz | 1995 |
Effects of serotonergic anxiolytics on physical dependence on diazepam in mice.
Topics: Animals; Anti-Anxiety Agents; Buspirone; Carbolines; Diazepam; Drug Synergism; Epilepsy, Tonic-Cloni | 1993 |
Non-convulsive status epilepticus in the adult mentally retarded. Classification and role of benzodiazepines.
Topics: Adult; Aged; Anti-Anxiety Agents; Brain Damage, Chronic; Cerebral Cortex; Diazepam; Drug Therapy, Co | 1993 |
Are rapid inpatient benzodiazepine detoxifications unsafe?
Topics: Adult; Anti-Anxiety Agents; Diazepam; Epilepsy, Tonic-Clonic; Female; Humans; Inpatients; Substance | 1993 |
The need for guidelines on the use of rectal diazepam.
Topics: Administration, Rectal; Adult; Child; Diazepam; Epilepsy; Epilepsy, Tonic-Clonic; First Aid; Humans; | 1993 |
Precipitated abstinence in the diazepam-dependent rat.
Topics: Animals; Behavior, Animal; Brain; Diazepam; Drug Implants; Epilepsy, Tonic-Clonic; Female; Flumazeni | 1993 |
[Acute chloroquine poisoning].
Topics: Anticonvulsants; Antidotes; Antimalarials; Chloroquine; Diazepam; Drug Overdose; Epilepsy, Tonic-Clo | 1997 |
Generalized tonic-clonic status epilepticus: causes, treatment, complications and predictors of case fatality.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Demography; Diazepam; Epilepsy, Tonic-Clonic; Femal | 1998 |
[Interpreting symptoms correctly. Who does one recognize a grand mal seizure? 3: Diagnosis and therapy of epileptic seizures].
Topics: Anticonvulsants; Diazepam; Drug Therapy, Combination; Emergencies; Epilepsy, Tonic-Clonic; Humans; S | 1998 |
Hanging-induced status epilepticus.
Topics: Adult; Anticonvulsants; Diazepam; Drug Therapy, Combination; Electroencephalography; Emergency Treat | 1999 |
Orphenadrine poisoning in a child: clinical and analytical data.
Topics: Akathisia, Drug-Induced; Anti-Arrhythmia Agents; Anticonvulsants; Antiparkinson Agents; Ataxia; Chil | 1999 |
NMDA- but not kainate-mediated events reduce efficacy of some antiepileptic drugs against generalized tonic-clonic seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Dose-Response Relationshi | 1999 |
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Lorazepam or diazepam for generalised convulsions in adults.
Topics: Diazepam; Emergency Medical Services; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Evidence-Based | 2001 |
[Epilepsy? Withdrawl symptoms and alcoholic hepatitis].
Topics: Chlormethiazole; Diagnosis, Differential; Diazepam; Epilepsy, Tonic-Clonic; Hepatitis, Alcoholic; Hu | 1978 |
Diazepam withdrawal syndrome: a case with psychosis, seizure, and coma.
Topics: Coma; Depressive Disorder, Major; Diazepam; Epilepsy, Tonic-Clonic; Humans; Male; Middle Aged; Psych | 1979 |
The medical treatment of epilepsy: treatment of prolonged convulsions and status epilepticus.
Topics: Adult; Anticonvulsants; Barbiturates; Child; Diazepam; Epilepsies, Myoclonic; Epilepsy, Tonic-Clonic | 1979 |
Withdrawal from diazepam.
Topics: Diazepam; Epilepsy, Tonic-Clonic; Humans; Substance Withdrawal Syndrome | 1977 |
Effects of antiepileptic drugs on thalamocortical excitability.
Topics: Animals; Bicuculline; Cats; Computers; Diazepam; Electric Stimulation; Electroencephalography; Epile | 1977 |
Letter: Diazepam withdrawal fits.
Topics: Diazepam; Epilepsy, Tonic-Clonic; Female; Humans; Substance Withdrawal Syndrome | 1975 |
Diseases of the central nervous system: Epilepsy.
Topics: Age Factors; Diazepam; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Eth | 1975 |
Problems of childhood. Febrile fits.
Topics: Age Factors; Child, Preschool; Diazepam; Epilepsy, Tonic-Clonic; Female; Fever; Humans; Infant; Male | 1976 |
The treatment and management of emergency status epilepticus.
Topics: Age Factors; Brain Edema; Child; Chlormethiazole; Diazepam; Emergencies; Epilepsy, Absence; Epilepsy | 1976 |
Withdrawal reaction to diazepam.
Topics: Adult; Diazepam; Epilepsy, Tonic-Clonic; Humans; Male; Substance Withdrawal Syndrome | 1976 |
Seizures after flumazenil administration in a case of combined benzodiazepine and tricyclic antidepressant overdose.
Topics: Adult; Clonazepam; Diazepam; Drug Overdose; Epilepsy, Tonic-Clonic; Female; Flumazenil; Humans; Imip | 1992 |
Intravenous valproate: onset and duration of anticonvulsant activity against a series of electroconvulsions in comparison with diazepam and phenytoin.
Topics: Animals; Anticonvulsants; Diazepam; Electric Stimulation; Electroshock; Epilepsy, Tonic-Clonic; Inje | 1992 |
Grand mal status epilepticus.
Topics: Alcoholism; Anticonvulsants; Diazepam; Epilepsy, Tonic-Clonic; Ethanol; Humans; Lorazepam; Male; Mid | 1992 |
The effect of ofloxacin and ciprofloxacin on pentylenetetrazol-induced convulsions in mice.
Topics: Animals; Ciprofloxacin; Diazepam; Epilepsy, Tonic-Clonic; Male; Mice; Ofloxacin; Pentylenetetrazole | 1991 |
Seizures associated with fluorescein angiography.
Topics: Adult; Diazepam; Emergencies; Epilepsy, Tonic-Clonic; Female; Fluorescein Angiography; Fluoresceins; | 1989 |
Diazepam loading for alcohol withdrawal: seizure risk in epileptics.
Topics: Administration, Oral; Adult; Alcohol Withdrawal Delirium; Alcoholism; Diazepam; Dose-Response Relati | 1989 |
[Grand mal seizures and status epilepticus in general practice-- what's to be done?].
Topics: Adult; Aged; Child, Preschool; Clonazepam; Diazepam; Emergencies; Epilepsy, Tonic-Clonic; Family Pra | 1986 |
[Clinical treatment of grand mal epileptic status in adults].
Topics: Adult; Barbiturates; Chlormethiazole; Clonazepam; Diazepam; Emergencies; Epilepsy, Tonic-Clonic; Hum | 1986 |
Emergency department management of children with acute isoniazid poisoning.
Topics: Adolescent; Child; Diazepam; Emergencies; Epilepsies, Partial; Epilepsy, Temporal Lobe; Epilepsy, To | 1986 |
Metabolism of magnesium and zinc in patients treated with antiepileptic drugs and with magnesium lactate.
Topics: Adult; Anticonvulsants; Carbamazepine; Diazepam; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Erythroc | 1987 |
Coarse features in epilepsy as a consequence of anticonvulsant therapy. Report of cases in two pairs of identical twins.
Topics: Acromegaly; Adult; Anticonvulsants; Carbamazepine; Child; Diazepam; Diseases in Twins; Epilepsy; Epi | 1973 |
Epilepsy.
Topics: Adrenocorticotropic Hormone; Carbamazepine; Diazepam; Drug Hypersensitivity; Drug-Related Side Effec | 1974 |
Comparative anticonvulsant effect of several Librium analogs.
Topics: Chlordiazepoxide; Diazepam; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal | 1967 |
Epilepsia partialis continua (EPC) and petit mal attacks observed in the same patient.
Topics: Adult; Diazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Female; Humans; Middle Aged | 1968 |
Antiepileptic therapy and rickets in children.
Topics: Adolescent; Anticonvulsants; Barbiturates; Child; Child, Preschool; Diazepam; Epilepsy; Epilepsy, To | 1973 |
Adverse reactions to intravenous diazepam: a report from the Boston Collaborative Drug Surveillance Program.
Topics: Adolescent; Adult; Aged; Anxiety; Apnea; Coma; Diazepam; Epilepsy, Tonic-Clonic; Female; Humans; Hyp | 1973 |
Diazepam treatment for acute convulsions in children. A report of 41 patients, three with plasma levels.
Topics: Adolescent; Age Factors; Brain Damage, Chronic; Brain Injuries; Child; Child, Preschool; Diazepam; E | 1974 |
Absorption of anticonvulsants after jejunoileal bypass.
Topics: Adult; Anticonvulsants; Diazepam; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Female; H | 1974 |
Letter: Treatment of status epilepticus with sodium valproate.
Topics: Adolescent; Anticonvulsants; Diazepam; Epilepsy, Tonic-Clonic; Female; Humans; Phenobarbital; Phenyt | 1974 |
[A case of valium withdrawal with grand mal attacks. A case report on valium abuse and valium addiction].
Topics: Adult; Diazepam; Epilepsy, Tonic-Clonic; Humans; Male; Substance Withdrawal Syndrome; Substance-Rela | 1974 |
Prolonged trance-like stupor in epilepsy. Petit mal status-wave stupor, spaced-out status.
Topics: Adult; Behavior; Diagnosis, Differential; Diazepam; Electroencephalography; Epilepsy; Epilepsy, Abse | 1974 |
[Unverricht-Lundborg myoclonic epilepsy in 3 siblings].
Topics: Adolescent; Age Factors; Child; Diazepam; Electroencephalography; Epilepsy, Tonic-Clonic; Female; Gl | 1971 |
[Early results (initial effects) of the treatment with mogadan in propulsive petit mal epilepsy].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Child; Child, Preschool; Diazepam; Electroencephalogra | 1968 |
Clinical, electroencephalographical and neuropharmacological studies in syndromes of progressive myoclonus epilepsy.
Topics: Administration, Oral; Adrenocorticotropic Hormone; Adult; Amobarbital; Benzazepines; Chloral Hydrate | 1970 |
Drug treatment of convulsive disorders.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Adult; Anticonvulsants; Barbiturates; Child; Diazepam; E | 1972 |
[Anticonvulsants. 7. Treatment of myclonic-astatic epilepsy in small children].
Topics: Acetazolamide; Adrenocorticotropic Hormone; Child, Preschool; Diazepam; Epilepsy, Absence; Epilepsy, | 1971 |
Classification and treatment of seizure disorders in children.
Topics: Acetazolamide; Adolescent; Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Child; Child, | 1970 |
Steroids, hypertension, and fluid retention in the genesis of postoperative seizures with inflammatory bowel disease in childhood.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Child; Colectomy; Colitis, Ulcerative; Cortisone; Cr | 1974 |
Drug treatment of epilepsy in childhood.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diazepam; Epilepsy; Epilepsy, Absence; Epil | 1969 |
[Therapy of epilepsy. The causes and consequences of inadequate treatment].
Topics: Acridines; Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Barbiturates; Carbamazepine; Child | 1972 |
Lignocaine overdose and ampoule labelling.
Topics: Aged; Diazepam; Drug Labeling; Epilepsy, Tonic-Clonic; Humans; Lidocaine; Male; Myocardial Infarctio | 1972 |
Diazepam (valium) in the treatment of epilepsy. A report of fifty cases.
Topics: Adolescent; Adult; Anticonvulsants; Child; Diazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal | 1965 |
Intravenous diazepam in the treatment of prolonged seizure activity.
Topics: Adolescent; Adult; Aged; Barbiturates; Child; Diazepam; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clo | 1967 |
Status epilepticus: a medical emergency.
Topics: Diazepam; Electroencephalography; Epilepsy, Tonic-Clonic; Humans; Injections, Intravenous; Paraldehy | 1967 |
Use of diazepam in treatment of severe convulsive status epilepticus.
Topics: Adolescent; Adult; Child; Diazepam; Epilepsy, Tonic-Clonic; Female; Humans; Infusions, Parenteral; I | 1967 |
[A new possibility in the treatment of status epilepticus in childhood with i.v. valium].
Topics: Child; Child, Preschool; Diazepam; Electroencephalography; Epilepsy, Absence; Epilepsy, Tonic-Clonic | 1966 |
[Therapeutic results of some benzodiazepines in chronic seizures in severe epilepsy in children].
Topics: Adolescent; Anticonvulsants; Benzazepines; Child; Diazepam; Epilepsy, Tonic-Clonic; Female; Humans; | 1966 |
Treatment of uncontrolled seizure activity with diazepam.
Topics: Acute Disease; Adolescent; Adult; Aged; Anticonvulsants; Brain Diseases; Child; Chronic Disease; Com | 1968 |
[Therapy of long-lasting cerebral swizures and of status epilepticus in childhood].
Topics: Age Factors; Barbiturates; Child; Diazepam; Epilepsy, Tonic-Clonic; Female; Humans; Injections, Intr | 1967 |
[Status elepticus].
Topics: Barbiturates; Diazepam; Epilepsy; Epilepsy, Tonic-Clonic; Humans; Phenytoin | 1967 |
[On the syndrome of progessive myoclonus epilepsy according to Lundborg. (A clinical course observation for fifteen years)].
Topics: Adult; Cachexia; Cerebellar Diseases; Dementia; Diazepam; Electroencephalography; Electromyography; | 1968 |
Dangers of treatment of status epilepticus with diazepam.
Topics: Adolescent; Adult; Aged; Cheyne-Stokes Respiration; Child; Diazepam; Drug Antagonism; Epilepsies, Pa | 1969 |
Status epilepticus and diazepam.
Topics: Child; Diazepam; Epilepsy, Tonic-Clonic; Humans; Hypotension | 1969 |
Status epilepticus and diazepam.
Topics: Diazepam; Epilepsy, Tonic-Clonic; Humans; Injections, Intravenous | 1969 |
Transitional electroencephalographic manifestations between ictal generalized spike-and-wave pattern and generalized repetitive fast discharge of the grand mal type.
Topics: Adolescent; Adult; Child; Diazepam; Electroencephalography; Epilepsy, Absence; Epilepsy, Tonic-Cloni | 1968 |
The long-term oral use of valium (diazepam) in epilepsy.
Topics: Adolescent; Adult; Child; Child, Preschool; Diazepam; Electroencephalography; Epilepsies, Partial; E | 1969 |
Electroencephalographic studies on the anticonvulsive action of intravenous diazepam.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Diazepam; Electroencephalography; Epile | 1970 |
[Treatment of status epilepticus].
Topics: Adult; Barbiturates; Child; Child, Preschool; Chloral Hydrate; Diazepam; Epilepsy, Tonic-Clonic; Hum | 1970 |
Intravenous diazepam and its anticonvulsive action.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Child, Preschool; Diazepam; Electroencephalography; | 1970 |
[Diazepam (Faustan) as a drug of choice for the treatment of status epilepticus and long-lasting attacks in childhood].
Topics: Child; Child, Preschool; Diazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Humans; Infa | 1970 |
Diazepam in the treatment of childhood epilepsy.
Topics: Administration, Oral; Age Factors; Child; Child, Preschool; Diazepam; Drug Tolerance; Electroencepha | 1971 |
[Problems of treatment of epilepsy].
Topics: Anemia, Macrocytic; Anticonvulsants; Bromides; Diazepam; Drug Synergism; Epilepsy; Epilepsy, Tempora | 1971 |
[Results of treatment of epilepsy in children up to 14 years of age].
Topics: Adolescent; Age Factors; Barbiturates; Child; Child, Preschool; Diazepam; Drug Synergism; Electroenc | 1971 |
[Cerebral seizures (conclusion). 4. Therapy].
Topics: Adult; Anticonvulsants; Child; Child, Preschool; Diazepam; Electroencephalography; Epilepsy; Epileps | 1971 |