diazepam has been researched along with Dystonia in 28 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have observed two cases of chlorpromazine-induced neuroleptic malignant syndrome (NMS); both were transiently responsive to intravenous diazepam challenge, but not to blind placebo or amyobarbitol." | 9.05 | Chlorpromazine-induced neuroleptic malignant syndrome and its response to diazepam. ( Lew, TY; Tollefson, G, 1983) |
| "Fourteen patients with spasmodic torticollis and other segmental dystonic syndromes, who were refractory to previous forms of therapy, were selected for treatment with drugs intended to elevate brain gamma-aminobutyric acid (GABA) levels." | 5.26 | Effect of L-glutamine and isoniazid on torticollis and segmental dystonia. ( Korein, J; Kupersmith, M; Levidow, L; Lieberman, A, 1981) |
| "We have observed two cases of chlorpromazine-induced neuroleptic malignant syndrome (NMS); both were transiently responsive to intravenous diazepam challenge, but not to blind placebo or amyobarbitol." | 5.05 | Chlorpromazine-induced neuroleptic malignant syndrome and its response to diazepam. ( Lew, TY; Tollefson, G, 1983) |
| " Oral administration of high dosage of anticholinergic drugs is firstly recommended for the treatment of dystonia." | 2.41 | [Medical treatment of dystonia]. ( Kachi, T, 2001) |
| "Isolated dystonia or spasticity was infrequently seen, with a mixed picture of dystonia and spasticity ± choreoathetosis identified in 194/275 (70." | 1.51 | Pharmacological management of abnormal tone and movement in cerebral palsy. ( Amin, S; Basu, A; Cadwgan, J; Crowe, B; DeAlwis, Y; Devlin, A; Kumar, R; Lodh, R; Lumsden, DE; Lundy, CT; Mordekar, SR; Smith, M, 2019) |
| "Case note review of 278 children with dystonia referred to our service." | 1.43 | Medication use in childhood dystonia. ( Kaminska, M; Lin, JP; Lumsden, DE; Tomlin, S, 2016) |
| "One patient had hemifacial spasm." | 1.35 | Syndrome of fixed dystonia in adolescents--short term outcome in 4 cases. ( Colomer, J; Fernández-Alvarez, E; Galvan, M; Jardine, PE; Lingappa, L; López-Casas, J; Majumdar, A; Poo, P; Short, C, 2009) |
| "Primary generalized dystonia (PGD) associated with the early-onset generalized dystonia gene (DYT1) can cause severe disability, compromising an individual's ability to perform activities of daily living." | 1.32 | Bilateral globus pallidus internus deep brain stimulation therapy for primary generalized dystonia. ( Abramovitch, AI; Charles, PD; Covington, CD; Davis, TL; Gill, CE; Konrad, PE; Newman, WJ; Padaliya, BB, 2004) |
| "Attacks of sustained dystonia of the limbs and trunk can be initiated by handling or mild environmental stimuli (e." | 1.29 | Alterations in pharmacological sensitivity of GABAergic but not dopaminergic and glutamatergic systems during ontogenesis in dystonic mutant hamsters. ( Löscher, W; Richter, A, 1993) |
| "Diazepam treatment significantly reduced the frequency of dystonic movements in the mutant." | 1.27 | Alterations in cerebellar glutamic acid decarboxylase (GAD) activity in a genetic model of torsion dystonia (rat). ( Beales, M; Gordon, JH; Lorden, JF; Oltmans, GA, 1984) |
| "Fourteen patients with spasmodic torticollis and other segmental dystonic syndromes, who were refractory to previous forms of therapy, were selected for treatment with drugs intended to elevate brain gamma-aminobutyric acid (GABA) levels." | 1.26 | Effect of L-glutamine and isoniazid on torticollis and segmental dystonia. ( Korein, J; Kupersmith, M; Levidow, L; Lieberman, A, 1981) |
| "Thirteen patients with acute dystonia and extrapyramidal symptoms as a result of drug intoxication are reported." | 1.26 | Treatment with diazepam of children with drug-induced extrapyramidal symptoms. ( Rainier-Pope, CR, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (50.00) | 18.7374 |
| 1990's | 8 (28.57) | 18.2507 |
| 2000's | 4 (14.29) | 29.6817 |
| 2010's | 2 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lumsden, DE | 2 |
| Crowe, B | 1 |
| Basu, A | 1 |
| Amin, S | 1 |
| Devlin, A | 1 |
| DeAlwis, Y | 1 |
| Kumar, R | 1 |
| Lodh, R | 1 |
| Lundy, CT | 1 |
| Mordekar, SR | 1 |
| Smith, M | 1 |
| Cadwgan, J | 1 |
| Kaminska, M | 1 |
| Tomlin, S | 1 |
| Lin, JP | 1 |
| Majumdar, A | 1 |
| López-Casas, J | 1 |
| Poo, P | 1 |
| Colomer, J | 1 |
| Galvan, M | 1 |
| Lingappa, L | 1 |
| Short, C | 1 |
| Jardine, PE | 1 |
| Fernández-Alvarez, E | 1 |
| Kachi, T | 1 |
| Hamann, M | 1 |
| Meisler, MH | 1 |
| Richter, A | 3 |
| Padaliya, BB | 1 |
| Davis, TL | 1 |
| Newman, WJ | 1 |
| Konrad, PE | 1 |
| Covington, CD | 1 |
| Gill, CE | 1 |
| Abramovitch, AI | 1 |
| Charles, PD | 1 |
| Dahiya, U | 1 |
| Noronha, P | 1 |
| Kaminer, Y | 1 |
| Modai, I | 1 |
| Lew, TY | 1 |
| Tollefson, G | 1 |
| Oltmans, GA | 1 |
| Beales, M | 1 |
| Lorden, JF | 1 |
| Gordon, JH | 1 |
| Korein, J | 1 |
| Lieberman, A | 1 |
| Kupersmith, M | 1 |
| Levidow, L | 1 |
| Bryant, SG | 1 |
| Löscher, W | 4 |
| Rosebush, PI | 1 |
| Mazurek, MF | 1 |
| Pina, MA | 1 |
| Ara, JR | 1 |
| Remírez, A | 1 |
| Castiella, J | 1 |
| Gruber Gikovate, C | 1 |
| Zirretta, JC | 1 |
| Ferreira Bezerra, JM | 1 |
| Canedo de Magalhães, G | 1 |
| Barkovich, AJ | 1 |
| Chong, SA | 1 |
| Remington, G | 1 |
| Tan, CH | 1 |
| Gagrat, D | 1 |
| Hamilton, J | 1 |
| Belmaker, RH | 1 |
| Rainier-Pope, CR | 1 |
| Di Monda, V | 1 |
| Fazzari, G | 1 |
| Callea, L | 1 |
| Adlmici, G | 1 |
| Ranganathan, G | 1 |
| Nammalwar, BR | 1 |
| Somu, N | 1 |
| Satyamurthy, V | 1 |
| Sivashanmugavel, S | 1 |
| Balagopal Raju, V | 1 |
| Fredow, G | 2 |
| Mets, B | 1 |
| Fisher, JE | 1 |
| Schmidt, D | 1 |
| Hönack, D | 1 |
| Iturrian, WB | 1 |
| Reddy, RV | 1 |
| Siemers, ER | 1 |
| Achumba, JI | 1 |
| Ette, EI | 1 |
| Thomas, WO | 1 |
| Essien, EE | 1 |
| Godbout, R | 1 |
| Montplaisir, J | 1 |
| Rouleau, I | 1 |
1 review available for diazepam and Dystonia
| Article | Year |
|---|---|
[Medical treatment of dystonia].
Topics: Cholinergic Antagonists; Clonazepam; Diazepam; Dopamine Antagonists; Dystonia; Humans; Levodopa; Tor | 2001 |
1 trial available for diazepam and Dystonia
| Article | Year |
|---|---|
Chlorpromazine-induced neuroleptic malignant syndrome and its response to diazepam.
Topics: Brain; Chlorpromazine; Diazepam; Dopamine; Dyskinesia, Drug-Induced; Dystonia; Female; Fever; gamma- | 1983 |
26 other studies available for diazepam and Dystonia
| Article | Year |
|---|---|
Pharmacological management of abnormal tone and movement in cerebral palsy.
Topics: Adolescent; Baclofen; Botulinum Toxins; Cerebral Palsy; Child; Child Health Services; Child, Prescho | 2019 |
Medication use in childhood dystonia.
Topics: Adolescent; Antiparkinson Agents; Baclofen; Child; Chloral Hydrate; Cohort Studies; Diazepam; Drug-R | 2016 |
Syndrome of fixed dystonia in adolescents--short term outcome in 4 cases.
Topics: Adolescent; Anxiety; Autonomic Nerve Block; Bites and Stings; Botulinum Toxins, Type A; Complex Regi | 2009 |
Motor disturbances in mice with deficiency of the sodium channel gene Scn8a show features of human dystonia.
Topics: Animals; Anti-Dyskinesia Agents; Anticonvulsants; Biperiden; Brain; Diazepam; Disease Models, Animal | 2003 |
Bilateral globus pallidus internus deep brain stimulation therapy for primary generalized dystonia.
Topics: Botulinum Toxins; Child; Deep Brain Stimulation; Diazepam; Dystonia; Globus Pallidus; Humans; Male; | 2004 |
Drug-induced acute dystonic reactions in children. Alternatives to diphenhydramine therapy.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benztropine; Child; Child, Preschool; Creatine Kinase; | 1984 |
Parenteral abuse of diazepam: a case report.
Topics: Adult; Diazepam; Dystonia; Factitious Disorders; Humans; Injections, Intravenous; Male; Substance-Re | 1984 |
Alterations in cerebellar glutamic acid decarboxylase (GAD) activity in a genetic model of torsion dystonia (rat).
Topics: Animals; Brain; Cerebellum; Diazepam; Disease Models, Animal; Dystonia; Glutamate Decarboxylase; His | 1984 |
Effect of L-glutamine and isoniazid on torticollis and segmental dystonia.
Topics: Adult; Diazepam; Drug Therapy, Combination; Dystonia; Glutamine; Humans; Isoniazid; Middle Aged; Pyr | 1981 |
Street drug misrepresentation.
Topics: Adult; Diazepam; Drug-Related Side Effects and Adverse Reactions; Dystonia; Haloperidol; Humans; Ill | 1980 |
(+)-WIN 55,212-2, a novel cannabinoid receptor agonist, exerts antidystonic effects in mutant dystonic hamsters.
Topics: Analgesics; Animals; Benzoxazines; Cricetinae; Diazepam; Disease Models, Animal; Dose-Response Relat | 1994 |
Do benzodiazepines modify the incidence of neuroleptic-induced dystonia?
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Diazepam; Dystonia; Humans; Schizophrenia | 1993 |
Alterations in pharmacological sensitivity of GABAergic but not dopaminergic and glutamatergic systems during ontogenesis in dystonic mutant hamsters.
Topics: Aging; Aminooxyacetic Acid; Animals; Cricetinae; Diazepam; Dopamine Antagonists; Dystonia; Mesocrice | 1993 |
Verapamil and acute dystonia.
Topics: Adult; Anti-Arrhythmia Agents; Diazepam; Dystonia; Female; Humans; Injections, Intravenous; Muscle R | 1998 |
Transient globus pallidus T1 shortening associated with polycythaemia and dystonia.
Topics: Basal Ganglia; Cerebellum; Child, Preschool; Diazepam; Dystonia; Female; Globus Pallidus; Humans; Im | 1999 |
Risperidone treatment of tardive dyskinesia and dystonia.
Topics: Antipsychotic Agents; Diazepam; Dopamine Antagonists; Drug Administration Schedule; Drug Therapy, Co | 1999 |
Intravenous diazepam in the treatment of neuroleptic-induced acute dystonia and akathisia.
Topics: Acute Disease; Akathisia, Drug-Induced; Antipsychotic Agents; Diazepam; Dyskinesia, Drug-Induced; Dy | 1978 |
Treatment with diazepam of children with drug-induced extrapyramidal symptoms.
Topics: Acute Disease; Child, Preschool; Diazepam; Dystonia; Female; Humans; Infant; Male; Parkinson Disease | 1979 |
[On a muscular dystony case from manganism. Therapeutic clinic considerations (author's transl)].
Topics: Benserazide; Diazepam; Dystonia; Haloperidol; Humans; Hydrazines; Levodopa; Male; Manganese; Middle | 1979 |
Preliminary study of diazepam in drug induced dystonia in children.
Topics: Child; Diazepam; Dystonia; Humans; Injections, Intravenous | 1978 |
Effects of pharmacological manipulation of GABAergic neurotransmission in a new mutant hamster model of paroxysmal dystonia.
Topics: Animals; Baclofen; Carbamazepine; Cricetinae; Diazepam; Disease Models, Animal; Dystonia; gamma-Amin | 1991 |
Acute dystonia after alfentanil in untreated Parkinson's disease.
Topics: Aged; Alfentanil; Diazepam; Dystonia; Female; Humans; Parkinson Disease; Preanesthetic Medication | 1991 |
The sz mutant hamster: a genetic model of epilepsy or of paroxysmal dystonia?
Topics: Animals; Cricetinae; Diazepam; Disease Models, Animal; Dystonia; Electroencephalography; Electromyog | 1989 |
Dystonia: therapy with high dosage anticholinergic medication.
Topics: Diazepam; Drug Therapy, Combination; Dystonia; Humans; Male; Middle Aged; Parasympatholytics; Phenot | 1987 |
Chloroquine-induced acute dystonic reactions in the presence of metronidazole.
Topics: Adult; Basal Ganglia Diseases; Chloroquine; Diazepam; Drug Interactions; Dystonia; Female; Humans; M | 1988 |
Hypnogenic paroxysmal dystonia: epilepsy or sleep disorder? A case report.
Topics: Adult; Carbamazepine; Diazepam; Dystonia; Epilepsy; Humans; Male; Sleep; Sleep Wake Disorders; Syndr | 1985 |