Page last updated: 2024-10-25

diazepam and Drug Overdose

diazepam has been researched along with Drug Overdose in 73 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.

Research Excerpts

ExcerptRelevanceReference
"To describe a case of mannitol overdose associated with acute kidney injury (AKI), hypertonic hyponatremia, and neurologic abnormalities in a dog."7.91Acute kidney injury, seizures, and hypertonic hyponatremia secondary to mannitol intoxication in a dog. ( Aumann, M; Clabots, MF; Gaillard, E, 2019)
"To report a case of serotonin syndrome (SS) after sibutramine overdose in a child."7.75Serotonin syndrome following sibutramine poisoning in a child, with sequential quantification of sibutramine and its primary and secondary amine metabolites in plasma. ( Barros, RF; Bucaretchi, F; da Costa, JL; de Capitani, EM; Fernandes, LC; Hyslop, S; Lanaro, R; Mello, SM, 2009)
" Its usefulness in a large-scale culture with a circulatory bioreactor in vitro and in dog models of ischemic hepatic failure with acute diazepam (DZP, a substrate of CYP3A4) overdosage was further examined."7.73The bioreactor with CYP3A4- and glutamine synthetase-introduced HepG2 cells: treatment of hepatic failure dog with diazepam overdosage. ( Enosawa, S; Fujimura, A; Matsumura, T; Nagai, H; Omasa, T; Sata, N; Tsuruoka, S; Wang, N; Yamamoto, H, 2005)
"He also had visual hallucinations and temporary high blood pressure."5.37Pharmacoresistant convulsions and visual hallucinations around two weeks after selegiline overdose: a case report. ( Kato, S; Kobayashi, T; Saito, N; Shioda, K; Suda, S, 2011)
"Mexiletine is a group Ib antidysrhythmic agent with electrophysiologic effects similar to lidocaine."5.29Mexiletine overdose producing status epilepticus without cardiovascular abnormalities. ( Hoffman, RS; Nelson, LS, 1994)
"Neither diazepam nor other ligands for benzodiazepine binding sites protect against or attenuate chloroquine cardiotoxicity."3.96Acute chloroquine poisoning: A comprehensive experimental toxicology assessment of the role of diazepam. ( Hughes, DA, 2020)
"To describe a case of mannitol overdose associated with acute kidney injury (AKI), hypertonic hyponatremia, and neurologic abnormalities in a dog."3.91Acute kidney injury, seizures, and hypertonic hyponatremia secondary to mannitol intoxication in a dog. ( Aumann, M; Clabots, MF; Gaillard, E, 2019)
"To report a case of serotonin syndrome (SS) after sibutramine overdose in a child."3.75Serotonin syndrome following sibutramine poisoning in a child, with sequential quantification of sibutramine and its primary and secondary amine metabolites in plasma. ( Barros, RF; Bucaretchi, F; da Costa, JL; de Capitani, EM; Fernandes, LC; Hyslop, S; Lanaro, R; Mello, SM, 2009)
" Treatment consisted of the rapid administration of intravenous diazepam, after which the hypotension recovered rapidly even though no vasoactive medication was given."3.74[Serious intoxication with hydroxychloroquine, with haemodynamic instability: a case report supporting treatment with diazepam]. ( Ligtenberg, JJ; Meertens, JH; Monteban-Kooistra, WE; Olgers, TJ; Tulleken, JE; Zijlstra, JG, 2008)
" Its usefulness in a large-scale culture with a circulatory bioreactor in vitro and in dog models of ischemic hepatic failure with acute diazepam (DZP, a substrate of CYP3A4) overdosage was further examined."3.73The bioreactor with CYP3A4- and glutamine synthetase-introduced HepG2 cells: treatment of hepatic failure dog with diazepam overdosage. ( Enosawa, S; Fujimura, A; Matsumura, T; Nagai, H; Omasa, T; Sata, N; Tsuruoka, S; Wang, N; Yamamoto, H, 2005)
" When sedation with benzodiazepines is carried out, the specific antagonist, flumazenil should always be available for use in emergencies such as accidental oversedation, iatrogenic overdose or paradoxical reactions."3.69Use of inhalational and intravenous sedation in dentistry. ( Rodrigo, MR, 1997)
"Alprazolam was significantly more toxic than other benzodiazepines."2.42Alprazolam is relatively more toxic than other benzodiazepines in overdose. ( Isbister, GK; O'Regan, L; Sibbritt, D; Whyte, IM, 2004)
"Epilepsy affects 1."2.41New antiepileptic drugs and preparations. ( Jagoda, A; Yoon, Y, 2000)
"Isoniazid has a low therapeutic margin and produces life threatening signs in dogs ingesting single 300 mg human tablets."2.39Treatment of acute isoniazid overdose in dogs. ( Barret, GH; Buck, WB; Holding, J; Knight, MK; Villar, D, 1995)
"Acute doses of diazepam or diclazepam result in the accumulation of oxycodone, whereas chronic administration induces the accumulation of oxymorphone, the toxic metabolite."1.91Metabolic interactions of benzodiazepines with oxycodone ex vivo and toxicity depending on usage patterns in an animal model. ( Bazgier, V; Čechová, P; El Balkhi, S; Javellaud, J; Lawson, R; Marquet, P; Otyepka, M; Picard, N; Saint-Marcoux, F; Trouillas, P; Zarrouk, E, 2023)
" Little is known about the toxic effects of etizolam overdose."1.72Toxicity of designer benzodiazepines: A case of etizolam and cocaine intoxication. ( Abbara, C; Briet, M; Drevin, G; Ferec, S, 2022)
"Tramadol is a synthetic opioid and poisoning is increasing around the world day by day."1.62Effects of naloxone and diazepam on blood glucose levels in tramadol overdose using generalized estimating equation (GEE) model; (an experimental study). ( Amirabadizadeh, A; Askari, M; Farrokhfall, K; Foadoddini, M; Mehrpour, O; Miri-Moghaddam, E; Nakhaee, S, 2021)
"Flumazenil was determined by liquid chromatography with mass spectrometry (LC-MS) in single ionmonitoring mode at m/z 304."1.43Determination of flumazenil in serum by liquid chromatography-mass spectrometry: Application to kinetics study in acute diazepam overdose. ( Djordjević, S; Jović-Stosić, J; Kilibarda, V; Perković-Vukcević, N; Segrt, Z, 2016)
"Respiratory failure and aspiration pneumonia occurred more frequently in old age."1.43Benzodiazepine poisoning in elderly. ( Djordjević, S; Ercegović, GV; Segrt, Z; Stosić, JJ; Vukcević, NP, 2016)
"female, with essential thrombocythemia, who was admitted to our clinic because of double suicidal ingestion of hydroxycarbamide."1.38Double, suicidal intoxication with hydroxycarbamide--a case report. ( Kabata, P; Sein Anand, J; Waldman, W, 2012)
"He also had visual hallucinations and temporary high blood pressure."1.37Pharmacoresistant convulsions and visual hallucinations around two weeks after selegiline overdose: a case report. ( Kato, S; Kobayashi, T; Saito, N; Shioda, K; Suda, S, 2011)
"This is a case report of a CPP treated by a pain physician."1.35Alleged breaches of "standards of medical care" in a patient overdose death possibly related to chronic opioid analgesic therapy, application of the controlled substances model guidelines: case report. ( Cole, B; Fishbain, DA; Gao, J; Lewis, JE; Rosomoff, RS, 2009)
"A ventricular fibrillation was treated with external cardiac massage."1.34[Treatment of hydroxychloroquine poisoning with extracorporeal circulation]. ( Blin, D; Derderian, F; Durand, M; Gonthier, YT; Mongenot, F, 2007)
"Refractory seizures not responding to benzodiazepine may require an antiepileptic drug."1.31Chloroquine poisoning: report of two cases. ( Reddy, VG; Sinna, S, 2000)
"Fenproporex is a sympathomimetic agent with a pharmacological profile similar to that of amphetamine."1.31A contemporaneous finding of fenproporex in a polydrug suicide. ( Bell, RR; Crookham, SB; Dunn, WA; Grates, KM; Reiber, TM, 2001)
"Mexiletine is a group Ib antidysrhythmic agent with electrophysiologic effects similar to lidocaine."1.29Mexiletine overdose producing status epilepticus without cardiovascular abnormalities. ( Hoffman, RS; Nelson, LS, 1994)

Research

Studies (73)

TimeframeStudies, this research(%)All Research%
pre-19902 (2.74)18.7374
1990's18 (24.66)18.2507
2000's23 (31.51)29.6817
2010's17 (23.29)24.3611
2020's13 (17.81)2.80

Authors

AuthorsStudies
Nakhaee, S1
Farrokhfall, K1
Miri-Moghaddam, E1
Askari, M1
Amirabadizadeh, A1
Foadoddini, M1
Mehrpour, O1
Lawson, R1
Čechová, P1
Zarrouk, E1
Javellaud, J1
Bazgier, V1
Otyepka, M1
Trouillas, P1
Picard, N1
Marquet, P1
Saint-Marcoux, F2
El Balkhi, S1
Srihari, P1
Minns, AB1
Gao, HT1
Kreshak, AA1
Drevin, G1
Briet, M1
Ferec, S1
Abbara, C1
Isbister, GK2
Polanski, R1
Cooper, JM1
Keegan, M1
Isoardi, KZ1
Lowrie, R1
McPherson, A1
Mair, FS1
Stock, K1
Jones, C1
Maguire, D1
Paudyal, V1
Duncan, C1
Blair, B1
Lombard, C1
Ross, S1
Hughes, F1
Moir, J1
Scott, A1
Reilly, F1
Sills, L1
Hislop, J1
Farmer, N1
Lucey, S1
Wishart, S1
Provan, G1
Robertson, R1
Williamson, A1
Walde, J1
Andersson, L1
Johnson, B1
Håkansson, A1
Tsutsumi, H1
Yonemitsu, K1
Sasao, A1
Ohtsu, Y1
Furukawa, S1
Nishitani, Y1
Runnstrom, M1
Kalra, SS1
Lascano, J1
Patel, DC1
Clabots, MF1
Gaillard, E1
Aumann, M1
Hughes, DA1
Chai, PR2
Ferro, EG2
Kirshenbaum, JM2
Hayes, BD2
Culbreth, SE2
Boyer, EW2
Erickson, TB2
Mégarbane, B2
Schicchi, A1
Couderc, S1
Mourou, H1
Monchaud, C1
Benesch, MGK1
Iqbal, SJ1
Calcaterra, NE1
Barrow, JC1
Mosich, V1
Müller-Busch, HC1
O'Connell, CW1
Sadler, CA1
Tolia, VM1
Ly, BT1
Saitman, AM1
Fitzgerald, RL1
Gibson, JL1
Nesbitt, I1
Dinsdale, A1
Walker, H1
Djordjević, S2
Jović-Stosić, J1
Kilibarda, V1
Segrt, Z2
Perković-Vukcević, N1
Vukcević, NP1
Ercegović, GV1
Stosić, JJ1
Zhang, P1
Austin, E1
Thompson, M1
Lin, S1
Lagard, C1
Chevillard, L1
Malissin, I1
Risède, P1
Callebert, J1
Labat, L1
Launay, JM1
Laplanche, JL1
Miller, EI1
Wylie, FM1
Oliver, JS1
Fishbain, DA1
Lewis, JE1
Gao, J1
Cole, B1
Rosomoff, RS1
Rochow, N1
Küster, H1
Bandt, C1
Hoffmann, U1
Fusch, C1
Bucaretchi, F1
de Capitani, EM1
Mello, SM1
Lanaro, R1
Barros, RF1
Fernandes, LC1
da Costa, JL1
Hyslop, S1
Watt, P1
Malik, D1
Dyson, L1
Golder, FJ1
Wilson, J1
Larenza, MP1
Fink, OT1
Rupasinghe, J1
Jasinarachchi, M1
Kobayashi, T1
Saito, N1
Suda, S1
Shioda, K1
Kato, S1
Cantrell, L1
Ukley, B1
Hermann, W1
Waldman, W1
Kabata, P1
Sein Anand, J1
Caksen, H1
Odabas, D1
Erol, M1
Anlar, O1
Tuncer, O1
Atas, B1
Spiller, HA1
Cutino, L1
HILLYER, DM1
Man, LH1
Best, D1
Gossop, M1
Stillwell, G1
Strang, J1
O'Regan, L1
Sibbritt, D1
Whyte, IM1
Kronstrand, R1
Nyström, I1
Strandberg, J1
Druid, H1
Yanturali, S1
Wilding, P1
Heath, DA1
Wang, N1
Tsuruoka, S1
Yamamoto, H1
Enosawa, S1
Omasa, T1
Sata, N1
Matsumura, T1
Nagai, H1
Fujimura, A1
Mongenot, F1
Gonthier, YT1
Derderian, F1
Durand, M1
Blin, D1
Eizadi-Mood, N1
Kanagarajan, K1
Marraffa, JM1
Bouchard, NC1
Krishnan, P1
Hoffman, RS2
Stork, CM1
da Cunha, AF1
Carter, JE1
Grafinger, M1
Montgomery, H1
Marks, SL1
Posner, LP1
Burns, P1
Olgers, TJ1
Tulleken, JE1
Monteban-Kooistra, WE1
Ligtenberg, JJ1
Meertens, JH1
Zijlstra, JG1
Sener, EK1
Gabe, S1
Henry, JA1
Nelson, LS1
Storrow, AB1
Stahl, MM1
Saldeen, P1
Vinge, E1
Zorzon, M1
Masè, G1
Biasutti, E1
Vitrani, B1
Cazzato, G1
Villar, D1
Knight, MK1
Holding, J1
Barret, GH1
Buck, WB1
Clemessy, JL1
Taboulet, P1
Hoffman, JR1
Hantson, P1
Barriot, P1
Bismuth, C1
Baud, FJ1
Altrock, G1
Lange, A1
Münster, P1
Rodrigo, MR1
Carriere, SR1
Elsworth, T1
Keller, T1
Schneider, A1
Tutsch-Bauer, E1
Reddy, VG1
Sinna, S1
Yoon, Y1
Jagoda, A1
James, M1
Vijayalakshmi, G1
Das, DG1
Brown, L1
Bergen, DC1
Kotagal, P1
Groves, L1
Carson, D1
Marquardt, K1
Albertson, TE1
Bell, RR1
Crookham, SB1
Dunn, WA1
Grates, KM1
Reiber, TM1
van Bao, T1
Imreh, E1
Czeizel, AE1
Korinihona, A1
Laurenson, IF1
Naraqi, S1
Mordel, A1
Winkler, E1
Almog, S1
Tirosh, M1
Ezra, D1
Stiff, G1
Robinson, D1
Cugnoni, HL1
Touquet, R1
Dalton, AM1
Lopez, A1
Rebollo, J1
Rajah, A1
Mahoney, JD1
Gross, PL1
Stern, TA1
Browne, BJ1
Pollack, MH1
Reder, V1
Mulley, AG1

Reviews

6 reviews available for diazepam and Drug Overdose

ArticleYear
Classics in chemical neuroscience: diazepam (valium).
    ACS chemical neuroscience, 2014, Apr-16, Volume: 5, Issue:4

    Topics: Anxiety Disorders; Diazepam; Dose-Response Relationship, Drug; Drug Design; Drug Overdose; Humans; R

2014
Alprazolam is relatively more toxic than other benzodiazepines in overdose.
    British journal of clinical pharmacology, 2004, Volume: 58, Issue:1

    Topics: Adolescent; Adult; Aged; Alprazolam; Anti-Anxiety Agents; Benzodiazepines; Critical Care; Diazepam;

2004
Bupropion overdose and seizure.
    The American journal of emergency medicine, 1994, Volume: 12, Issue:2

    Topics: Adolescent; Bupropion; Charcoal; Diazepam; Drug Overdose; Electrocardiography; Emergency Service, Ho

1994
Treatment of acute isoniazid overdose in dogs.
    Veterinary and human toxicology, 1995, Volume: 37, Issue:5

    Topics: Administration, Oral; Animals; Anticonvulsants; Antitubercular Agents; Cats; Diazepam; Dog Diseases;

1995
New antiepileptic drugs and preparations.
    Emergency medicine clinics of North America, 2000, Volume: 18, Issue:4

    Topics: Acetates; Administration, Rectal; Age Factors; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids;

2000
Chloroquine overdose in adults: a practical approach to management.
    Papua and New Guinea medical journal, 1992, Volume: 35, Issue:4

    Topics: Adult; Child; Chloroquine; Clinical Protocols; Diazepam; Drug Overdose; Epinephrine; Female; Humans;

1992

Trials

1 trial available for diazepam and Drug Overdose

ArticleYear
Baseline characteristics of people experiencing homelessness with a recent drug overdose in the PHOENIx pilot randomised controlled trial.
    Harm reduction journal, 2023, 04-04, Volume: 20, Issue:1

    Topics: Adult; Diazepam; Drug Overdose; Female; Heroin; Humans; Ill-Housed Persons; Male; Pilot Projects

2023

Other Studies

66 other studies available for diazepam and Drug Overdose

ArticleYear
Effects of naloxone and diazepam on blood glucose levels in tramadol overdose using generalized estimating equation (GEE) model; (an experimental study).
    BMC endocrine disorders, 2021, Sep-06, Volume: 21, Issue:1

    Topics: Analgesics, Opioid; Animals; Blood Glucose; Diazepam; Drug Overdose; Hyperglycemia; Hypnotics and Se

2021
Metabolic interactions of benzodiazepines with oxycodone ex vivo and toxicity depending on usage patterns in an animal model.
    British journal of pharmacology, 2023, Volume: 180, Issue:7

    Topics: Analgesics, Opioid; Animals; Benzodiazepines; Cytochrome P-450 CYP3A; Diazepam; Drug Overdose; Human

2023
Massive Nonfatal Hydroxychloroquine Ingestion in a Pediatric Patient.
    The Journal of emergency medicine, 2022, Volume: 62, Issue:3

    Topics: Adolescent; Child; Diazepam; Drug Overdose; Eating; Epinephrine; Female; Humans; Hydroxychloroquine;

2022
Toxicity of designer benzodiazepines: A case of etizolam and cocaine intoxication.
    Forensic science international, 2022, Volume: 336

    Topics: Adult; Benzodiazepines; Chromatography, Liquid; Cocaine; Diazepam; Drug Overdose; Humans; Male

2022
Duloxetine overdose causes sympathomimetic and serotonin toxicity without major complications.
    Clinical toxicology (Philadelphia, Pa.), 2022, Volume: 60, Issue:9

    Topics: Acetaminophen; Adult; Antidepressive Agents; Arrhythmias, Cardiac; Coma; Diazepam; Droperidol; Drug

2022
Drug prescriptions preceding opioid-related deaths-a register study in forensic autopsy patients.
    PloS one, 2023, Volume: 18, Issue:5

    Topics: Alprazolam; Analgesics, Opioid; Autopsy; Diazepam; Drug Overdose; Drug Prescriptions; Humans; Opioid

2023
Cerebrospinal fluid neurotransmitter levels and central nervous system depression in a rat drug overdose model.
    Toxicology mechanisms and methods, 2020, Volume: 30, Issue:2

    Topics: Administration, Oral; Animals; Biomarkers; Carboxymethylcellulose Sodium; Chromatography, Liquid; Di

2020
Overdose from designer benzodiazepine Diclazepam.
    QJM : monthly journal of the Association of Physicians, 2020, Feb-01, Volume: 113, Issue:2

    Topics: Adult; Benzodiazepines; Coma; Designer Drugs; Diazepam; Drug Overdose; Glasgow Coma Scale; Humans; M

2020
Acute kidney injury, seizures, and hypertonic hyponatremia secondary to mannitol intoxication in a dog.
    Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 2019, Volume: 29, Issue:6

    Topics: Acute Kidney Injury; Animals; Anticonvulsants; Creatinine; Diazepam; Dog Diseases; Dogs; Drug Overdo

2019
Acute chloroquine poisoning: A comprehensive experimental toxicology assessment of the role of diazepam.
    British journal of pharmacology, 2020, Volume: 177, Issue:21

    Topics: Animals; Arrhythmias, Cardiac; Benzodiazepinones; Cardiotoxicity; Chloroquine; Clonazepam; Coronavir

2020
Intentional Hydroxychloroquine Overdose Treated with High-Dose Diazepam: an Increasing Concern in the COVID-19 Pandemic.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2020, Volume: 16, Issue:3

    Topics: Adult; Coronavirus Infections; COVID-19; Diazepam; Drug Overdose; Drug-Related Side Effects and Adve

2020
In Reply to "Hydroxychloroquine Overdose: What Are the Exact Roles of Diazepam and Potassium Infusion?"
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2021, Volume: 17, Issue:1

    Topics: COVID-19 Drug Treatment; Diazepam; Drug Overdose; Humans; Hydroxychloroquine; Pandemics; Potassium;

2021
Hydroxychloroquine Overdose: What Are the Exact Roles of Diazepam and Potassium Infusion?
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2021, Volume: 17, Issue:1

    Topics: COVID-19 Drug Treatment; Diazepam; Drug Overdose; Humans; Hydroxychloroquine; Pandemics; Potassium;

2021
Unsuccessful Suicide Attempt With Tiapride.
    Therapeutic drug monitoring, 2017, Volume: 39, Issue:6

    Topics: Adolescent; Anti-Anxiety Agents; Antipsychotic Agents; Diazepam; Drug Monitoring; Drug Overdose; Fem

2017
Novel psychoactive substances: overdose of 3-fluorophenmetrazine (3-FPM) and etizolam in a 33-year-old man.
    BMJ case reports, 2018, Jun-08, Volume: 2018

    Topics: Adult; Diazepam; Disease Management; Drug Overdose; Humans; Male; Patient Admission; Phenmetrazine

2018
[Suicidal drug overdose while receiving palliative home care: a case report].
    Wiener medizinische Wochenschrift (1946), 2014, Volume: 164, Issue:9-10

    Topics: Aged, 80 and over; Austria; Bromazepam; Carcinoma, Bronchogenic; Decision Making; Diazepam; Drug Ove

2014
Overdose of etizolam: the abuse and rise of a benzodiazepine analog.
    Annals of emergency medicine, 2015, Volume: 65, Issue:4

    Topics: Adult; Diazepam; Drug Overdose; Emergency Service, Hospital; Humans; Male; Substance-Related Disorde

2015
Survival of ingestion of a potentially lethal dose of caffeine.
    British journal of hospital medicine (London, England : 2005), 2016, Volume: 77, Issue:2

    Topics: Adult; Antihypertensive Agents; Caffeine; Diazepam; Drug Overdose; Hemodiafiltration; Humans; Hypnot

2016
Determination of flumazenil in serum by liquid chromatography-mass spectrometry: Application to kinetics study in acute diazepam overdose.
    Vojnosanitetski pregled, 2016, Volume: 73, Issue:2

    Topics: Aminophylline; Antidotes; Chromatography, Liquid; Diazepam; Dimensional Measurement Accuracy; Dose-R

2016
Benzodiazepine poisoning in elderly.
    Vojnosanitetski pregled, 2016, Volume: 73, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antidotes; Benzodiazepines; Bromazepam; Coh

2016
Challenges in a large mixed drug overdose patient.
    BMJ case reports, 2016, Jun-22, Volume: 2016

    Topics: Adult; Anticonvulsants; Body Temperature Regulation; Critical Care; Delirium; Diazepam; Drug Overdos

2016
Mechanisms of tramadol-related neurotoxicity in the rat: Does diazepam/tramadol combination play a worsening role in overdose?
    Toxicology and applied pharmacology, 2016, Nov-01, Volume: 310

    Topics: Analgesics, Opioid; Animals; Brain; Diazepam; Dose-Response Relationship, Drug; Drug Overdose; Male;

2016
Simultaneous detection and quantification of amphetamines, diazepam and its metabolites, cocaine and its metabolites, and opiates in hair by LC-ESI-MS-MS using a single extraction method.
    Journal of analytical toxicology, 2008, Volume: 32, Issue:7

    Topics: Amphetamines; Analgesics, Opioid; Buffers; Chromatography, High Pressure Liquid; Cocaine; Diazepam;

2008
Alleged breaches of "standards of medical care" in a patient overdose death possibly related to chronic opioid analgesic therapy, application of the controlled substances model guidelines: case report.
    Pain medicine (Malden, Mass.), 2009, Volume: 10, Issue:3

    Topics: Adult; Analgesics, Opioid; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Diazepam; Doxepin;

2009
Case 1: Unexpected muscular hypotonia and need for mechanical ventilation in a preterm infant. Prolonged effect of diazepam.
    Acta paediatrica (Oslo, Norway : 1992), 2008, Volume: 97, Issue:12

    Topics: Adult; Diazepam; Drug Overdose; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, N

2008
Serotonin syndrome following sibutramine poisoning in a child, with sequential quantification of sibutramine and its primary and secondary amine metabolites in plasma.
    Clinical toxicology (Philadelphia, Pa.), 2009, Volume: 47, Issue:6

    Topics: Antidotes; Appetite Depressants; Child, Preschool; Chloral Hydrate; Chromatography, High Pressure Li

2009
Gift of the glob--is it foolproof?
    Anaesthesia, 2009, Volume: 64, Issue:9

    Topics: Acetaminophen; Adult; Antipsychotic Agents; Diazepam; Dibenzothiazepines; Drug Overdose; Fat Emulsio

2009
Suspected acute meperidine toxicity in a dog.
    Veterinary anaesthesia and analgesia, 2010, Volume: 37, Issue:5

    Topics: Adjuvants, Anesthesia; Anesthesia, General; Animals; Anticonvulsants; Central Nervous System; Diazep

2010
Progressive encephalopathy with cerebral oedema and infarctions associated with valproate and diazepam overdose.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2011, Volume: 18, Issue:5

    Topics: Adult; Antimanic Agents; Brain Edema; Brain Infarction; Chemical and Drug Induced Liver Injury; Coma

2011
Pharmacoresistant convulsions and visual hallucinations around two weeks after selegiline overdose: a case report.
    Pharmacopsychiatry, 2011, Volume: 44, Issue:7

    Topics: Anticonvulsants; Bipolar Disorder; Coma; Diazepam; Drug Overdose; Drug Resistance; Hallucinations; H

2011
Redotex® revisited: intentional overdose with an illegal weight loss product.
    The Journal of emergency medicine, 2012, Volume: 43, Issue:2

    Topics: Adolescent; Anti-Obesity Agents; Atropine; Charcoal; Diazepam; Drug Combinations; Drug Overdose; Emo

2012
[Subacute Parkinson's disease after suicide attempt with diazepam].
    Der Nervenarzt, 2013, Volume: 84, Issue:2

    Topics: Adult; Antiparkinson Agents; Cerebellum; Diazepam; Disease Progression; Drug Overdose; Follow-Up Stu

2013
Double, suicidal intoxication with hydroxycarbamide--a case report.
    Przeglad lekarski, 2012, Volume: 69, Issue:8

    Topics: Adult; Complex Mixtures; Diazepam; Drug Overdose; Ethanol; Female; Humans; Hydroxyurea; Paroxetine;

2012
Do not overlook acute isoniazid poisoning in children with status epilepticus.
    Journal of child neurology, 2003, Volume: 18, Issue:2

    Topics: Acidosis; Antitubercular Agents; Child, Preschool; Diagnosis, Differential; Diazepam; Drug Overdose;

2003
Fatal cyclobenzaprine overdose with postmortem values.
    Journal of forensic sciences, 2003, Volume: 48, Issue:4

    Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Diazepam; Drug Overdose; Ethanol; Female; Humans; Ma

2003
AN OVERDOSE OF "VALIUM".
    The Medical journal of Australia, 1965, Volume: 1

    Topics: Ataxia; Diazepam; Drug Overdose; Drug Tolerance; Pharmacology; Toxicology

1965
Relationship between prescribing and risk of opiate overdose among drug users in and out of maintenance treatment.
    European addiction research, 2004, Volume: 10, Issue:1

    Topics: Adult; Alcoholic Intoxication; Benzodiazepines; Causality; Cocaine-Related Disorders; Comorbidity; C

2004
Screening for drugs of abuse in hair with ion spray LC-MS-MS.
    Forensic science international, 2004, Oct-29, Volume: 145, Issue:2-3

    Topics: Amphetamines; Anti-Anxiety Agents; Central Nervous System Stimulants; Chromatography, Liquid; Cocain

2004
Diazepam for treatment of massive chloroquine intoxication.
    Resuscitation, 2004, Volume: 63, Issue:3

    Topics: Arrhythmias, Cardiac; Cardiovascular Agents; Diazepam; Drug Overdose; Female; Humans; Hydroxychloroq

2004
Effect of paracetamol on uric acid determination.
    Annals of clinical biochemistry, 1975, Volume: 12, Issue:4

    Topics: Acetaminophen; Adult; Anticonvulsants; Autoanalysis; Bromides; Diazepam; Dose-Response Relationship,

1975
The bioreactor with CYP3A4- and glutamine synthetase-introduced HepG2 cells: treatment of hepatic failure dog with diazepam overdosage.
    Artificial organs, 2005, Volume: 29, Issue:8

    Topics: Animals; Bioreactors; Cell Line; Cricetinae; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System;

2005
[Treatment of hydroxychloroquine poisoning with extracorporeal circulation].
    Annales francaises d'anesthesie et de reanimation, 2007, Volume: 26, Issue:2

    Topics: Adult; Antidotes; Bromazepam; Charcoal; Coma; Combined Modality Therapy; Diazepam; Drug Overdose; Ep

2007
Nalidixic acid overdose and metabolic acidosis.
    CJEM, 2006, Volume: 8, Issue:2

    Topics: Acidosis; Adolescent; Anti-Infective Agents; Anticonvulsants; Cognition Disorders; Diazepam; Drug Ov

2006
The use of vasopressin in the setting of recalcitrant hypotension due to calcium channel blocker overdose.
    Clinical toxicology (Philadelphia, Pa.), 2007, Volume: 45, Issue:1

    Topics: Adult; Amlodipine; Antidotes; Blood Pressure; Calcium Channel Blockers; Diazepam; Diltiazem; Drug Ov

2007
Intrathecal morphine overdose in a dog.
    Journal of the American Veterinary Medical Association, 2007, Jun-01, Volume: 230, Issue:11

    Topics: Animals; Atracurium; Diazepam; Dog Diseases; Dogs; Drug Overdose; Epilepsies, Myoclonic; Female; Inf

2007
[Serious intoxication with hydroxychloroquine, with haemodynamic instability: a case report supporting treatment with diazepam].
    Nederlands tijdschrift voor geneeskunde, 2008, Mar-01, Volume: 152, Issue:9

    Topics: Adult; Diazepam; Drug Overdose; Female; Humans; Hydroxychloroquine; Hypotension; Treatment Outcome

2008
Response to glucagon in imipramine overdose.
    Journal of toxicology. Clinical toxicology, 1995, Volume: 33, Issue:1

    Topics: Adult; Diazepam; Drug Overdose; Electrocardiography; Female; Glucagon; Humans; Imipramine; Infusions

1995
Mexiletine overdose producing status epilepticus without cardiovascular abnormalities.
    Journal of toxicology. Clinical toxicology, 1994, Volume: 32, Issue:6

    Topics: Adult; Blood Pressure; Cardiovascular System; Diazepam; Drug Overdose; Drug Therapy, Combination; El

1994
Reversal of fetal benzodiazepine intoxication using flumazenil.
    British journal of obstetrics and gynaecology, 1993, Volume: 100, Issue:2

    Topics: Adult; Cardiotocography; Diazepam; Drug Overdose; Female; Fetal Diseases; Flumazenil; Gastric Lavage

1993
Acute encephalopathy and polyneuropathy after disulfiram intoxication.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1995, Volume: 30, Issue:5

    Topics: Adult; Alcohol Deterrents; Alcoholism; Diazepam; Disulfiram; Dose-Response Relationship, Drug; Drug

1995
Treatment of acute chloroquine poisoning: a 5-year experience.
    Critical care medicine, 1996, Volume: 24, Issue:7

    Topics: Acute Disease; Adult; Chloroquine; Combined Modality Therapy; Diazepam; Drug Overdose; Drug Therapy,

1996
[Acute chloroquine poisoning].
    Deutsche medizinische Wochenschrift (1946), 1997, Feb-21, Volume: 122, Issue:8

    Topics: Anticonvulsants; Antidotes; Antimalarials; Chloroquine; Diazepam; Drug Overdose; Epilepsy, Tonic-Clo

1997
Use of inhalational and intravenous sedation in dentistry.
    International dental journal, 1997, Volume: 47, Issue:1

    Topics: Accidents; Anesthesia, Dental; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthesia, Local; A

1997
Found down: compartment syndrome, rhabdomyolysis, and renal failure.
    Journal of emergency nursing, 1998, Volume: 24, Issue:3

    Topics: Acute Kidney Injury; Compartment Syndromes; Diazepam; Drug Overdose; Emergency Nursing; Female; Huma

1998
Fatal intoxication due to dothiepin.
    Forensic science international, 2000, Mar-27, Volume: 109, Issue:2

    Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Autopsy; Body Fluids; Diazepam; Dothie

2000
Chloroquine poisoning: report of two cases.
    Acta anaesthesiologica Scandinavica, 2000, Volume: 44, Issue:8

    Topics: Adult; Anticonvulsants; Antidotes; Antimalarials; Charcoal; Chloroquine; Coma; Diazepam; Drug Overdo

2000
Massive dose of diazepam poisoning.
    The Journal of the Association of Physicians of India, 1998, Volume: 46, Issue:11

    Topics: Diazepam; Dose-Response Relationship, Drug; Drug Overdose; Flumazenil; Gastric Lavage; Humans; Infus

1998
Safety of Diastat when given at larger-than-recommended doses for acute repetitive seizures.
    Neurology, 2001, Apr-24, Volume: 56, Issue:8

    Topics: Administration, Rectal; Adolescent; Adult; Aged; Anticonvulsants; Child; Child, Preschool; Diazepam;

2001
Treatment of hydroxychloroquine overdose.
    The American journal of emergency medicine, 2001, Volume: 19, Issue:5

    Topics: Adolescent; Adrenergic Agonists; Antirheumatic Agents; Cardiotonic Agents; Charcoal; Diazepam; Dopam

2001
A contemporaneous finding of fenproporex in a polydrug suicide.
    Journal of analytical toxicology, 2001, Volume: 25, Issue:7

    Topics: Adult; Amphetamines; Anti-Allergic Agents; Anticonvulsants; Appetite Depressants; Autopsy; Diazepam;

2001
Cytogenetic effects of diazepam in peripheral lymphocytes of self-poisoned persons.
    Mutation research, 1992, Volume: 298, Issue:2

    Topics: Adolescent; Adult; Aneuploidy; Chi-Square Distribution; Diazepam; Drug Overdose; Female; Humans; Lym

1992
Seizures after flumazenil administration in a case of combined benzodiazepine and tricyclic antidepressant overdose.
    Critical care medicine, 1992, Volume: 20, Issue:12

    Topics: Adult; Clonazepam; Diazepam; Drug Overdose; Epilepsy, Tonic-Clonic; Female; Flumazenil; Humans; Imip

1992
Massive chloroquine overdose--a survivor.
    Postgraduate medical journal, 1991, Volume: 67, Issue:789

    Topics: Adult; Chloroquine; Diazepam; Drug Overdose; Female; Humans; Suicide, Attempted

1991
Benzodiazepine withdrawal syndrome after a benzodiazepine antagonist.
    Critical care medicine, 1990, Volume: 18, Issue:12

    Topics: Adolescent; Akathisia, Drug-Induced; Diazepam; Drug Overdose; Flumazenil; Humans; Injections, Intrav

1990
The use of diazepam in chloroquine poisoning.
    Anaesthesia, 1990, Volume: 45, Issue:11

    Topics: Adult; Chloroquine; Diazepam; Drug Overdose; Female; Gastric Lavage; Humans; Poisoning

1990
Quantitative serum toxic screening in the management of suspected drug overdose.
    The American journal of emergency medicine, 1990, Volume: 8, Issue:1

    Topics: Acetaminophen; Alcoholic Intoxication; Antidepressive Agents, Tricyclic; Barbiturates; Blood Chemica

1990