diazepam has been researched along with Disorders of Excessive Somnolence in 6 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Disorders of Excessive Somnolence: Disorders characterized by hypersomnolence during normal waking hours that may impair cognitive functioning. Subtypes include primary hypersomnia disorders (e.g., IDIOPATHIC HYPERSOMNOLENCE; NARCOLEPSY; and KLEINE-LEVIN SYNDROME) and secondary hypersomnia disorders where excessive somnolence can be attributed to a known cause (e.g., drug affect, MENTAL DISORDERS, and SLEEP APNEA SYNDROME). (From J Neurol Sci 1998 Jan 8;153(2):192-202; Thorpy, Principles and Practice of Sleep Medicine, 2nd ed, p320)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diazepam rectal gel was effective in stopping seizures in 45 patients (90%)." | 6.73 | Effectiveness of diazepam rectal gel in adults with acute repetitive seizures and prolonged seizures: a single-center experience. ( Bensalem-Owen, M; Chumley, A; Fakhoury, T, 2007) |
| "This review provides moderate-quality evidence that fails to support the use of GABA receptor agonists (chlormethiazole or diazepam) for the treatment of people with acute stroke." | 4.98 | Gamma aminobutyric acid (GABA) receptor agonists for acute stroke. ( Liu, J; Wang, LN; Zhang, J, 2018) |
| "This review provides moderate-quality evidence that fails to support the use of GABA receptor agonists (chlormethiazole or diazepam) for the treatment of people with acute stroke." | 4.93 | Gamma aminobutyric acid (GABA) receptor agonists for acute stroke. ( Ji, X; Liu, J; Ma, X; Wang, LN, 2016) |
| "This review does not provide the evidence to support the use of GABA receptor agonists (chlormethiazole or diazepam) for the treatment of patients with acute ischemic or hemorrhagic stroke." | 4.90 | Gamma aminobutyric acid (GABA) receptor agonists for acute stroke. ( Liu, J; Wang, LN, 2014) |
| "Diazepam rectal gel was effective in stopping seizures in 45 patients (90%)." | 2.73 | Effectiveness of diazepam rectal gel in adults with acute repetitive seizures and prolonged seizures: a single-center experience. ( Bensalem-Owen, M; Chumley, A; Fakhoury, T, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, J | 3 |
| Zhang, J | 1 |
| Wang, LN | 3 |
| Ma, X | 1 |
| Ji, X | 1 |
| Fakhoury, T | 1 |
| Chumley, A | 1 |
| Bensalem-Owen, M | 1 |
| Holt, RJ | 1 |
| Pérez-Cruet, J | 1 |
| Blackwell, B | 1 |
4 reviews available for diazepam and Disorders of Excessive Somnolence
| Article | Year |
|---|---|
Gamma aminobutyric acid (GABA) receptor agonists for acute stroke.
Topics: Acute Disease; Chlormethiazole; Diazepam; Disorders of Excessive Somnolence; GABA Agonists; gamma-Am | 2018 |
Gamma aminobutyric acid (GABA) receptor agonists for acute stroke.
Topics: Acute Disease; Chlormethiazole; Diazepam; Disorders of Excessive Somnolence; GABA Agonists; Humans; | 2014 |
Gamma aminobutyric acid (GABA) receptor agonists for acute stroke.
Topics: Acute Disease; Chlormethiazole; Diazepam; Disorders of Excessive Somnolence; GABA Agonists; Humans; | 2016 |
A critical review of oxazepam: efficacy and specificity.
Topics: Age Factors; Aged; Chlordiazepoxide; Clinical Trials as Topic; Diazepam; Disorders of Excessive Somn | 1975 |
2 trials available for diazepam and Disorders of Excessive Somnolence
| Article | Year |
|---|---|
Effectiveness of diazepam rectal gel in adults with acute repetitive seizures and prolonged seizures: a single-center experience.
Topics: Acute Disease; Administration, Rectal; Adolescent; Adult; Anticonvulsants; Body Weight; Diazepam; Di | 2007 |
A critical review of oxazepam: efficacy and specificity.
Topics: Age Factors; Aged; Chlordiazepoxide; Clinical Trials as Topic; Diazepam; Disorders of Excessive Somn | 1975 |
1 other study available for diazepam and Disorders of Excessive Somnolence
| Article | Year |
|---|---|
Hypersomnic diazepam abstinence syndrome: a case report.
Topics: Adult; Antisocial Personality Disorder; Cyclothymic Disorder; Diazepam; Disorders of Excessive Somno | 1982 |