diazepam has been researched along with Disease Exacerbation in 12 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our data demonstrate an anticonvulsant effect of bumetanide on KA-induced seizures in adult mice, suggesting a role for chloride plasticity in seizure progression." | 7.83 | Bumetanide reduces seizure progression and the development of pharmacoresistant status epilepticus. ( Maguire, J; Sivakumaran, S, 2016) |
| " A tracheostomy was established to relieve airway obstruction, and ketamine was added to the medication when breakthrough seizures were refractory to diazepam." | 7.74 | Ketamine in the management of generalised cephalic tetanus. ( Amadasun, JE; Obanor, O; Osazuwa, HO, 2008) |
| "Our data demonstrate an anticonvulsant effect of bumetanide on KA-induced seizures in adult mice, suggesting a role for chloride plasticity in seizure progression." | 3.83 | Bumetanide reduces seizure progression and the development of pharmacoresistant status epilepticus. ( Maguire, J; Sivakumaran, S, 2016) |
| " Using pimonidazole, which probes hypoxic insults, we found that by increasing the duration of pilocarpine-induced status epilepticus (SE) from 30 to 120 min, counts of pimonidazole-immunoreactive neurons also increased (P < 0." | 3.79 | Hypoxia markers are expressed in interneurons exposed to recurrent seizures. ( Biagini, G; Gualtieri, F; Longo, D; Marinelli, C; Meletti, S; Nichelli, PF; Pugnaghi, M, 2013) |
| " A tracheostomy was established to relieve airway obstruction, and ketamine was added to the medication when breakthrough seizures were refractory to diazepam." | 3.74 | Ketamine in the management of generalised cephalic tetanus. ( Amadasun, JE; Obanor, O; Osazuwa, HO, 2008) |
| "Neonatal-type nonketotic hyperglycinemia treatment remains unsatisfactory, even if started early." | 1.32 | Poor outcome for neonatal-type nonketotic hyperglycinemia treated with high-dose sodium benzoate and dextromethorphan. ( Chien, YH; Chou, SP; Hsu, CC; Huang, A; Hwu, WL; Lee, WT; Lu, FL, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shakarjian, MP | 1 |
| Ali, MS | 1 |
| Velíšková, J | 1 |
| Stanton, PK | 1 |
| Heck, DE | 1 |
| Velíšek, L | 1 |
| Sivakumaran, S | 1 |
| Maguire, J | 1 |
| Wang, NC | 1 |
| Good, LB | 1 |
| Marsh, ST | 1 |
| Treiman, DM | 1 |
| Mathew, PJ | 1 |
| Samra, T | 1 |
| Wig, J | 1 |
| Perez-Mendes, P | 1 |
| Blanco, MM | 1 |
| Calcagnotto, ME | 1 |
| Cinini, SM | 1 |
| Bachiega, J | 1 |
| Papoti, D | 1 |
| Covolan, L | 1 |
| Tannus, A | 1 |
| Mello, LE | 1 |
| Gomes, EP | 1 |
| Aguiar, JC | 1 |
| Fonseca-Silva, T | 1 |
| Dias, LC | 1 |
| Moura-Boas, KP | 1 |
| Roy, A | 1 |
| Velloso, NA | 1 |
| Rodrigues-Neto, JF | 1 |
| De-Paula, AM | 1 |
| Guimarães, AL | 1 |
| Gualtieri, F | 1 |
| Marinelli, C | 1 |
| Longo, D | 1 |
| Pugnaghi, M | 1 |
| Nichelli, PF | 1 |
| Meletti, S | 1 |
| Biagini, G | 1 |
| Ukley, B | 1 |
| Hermann, W | 1 |
| Chien, YH | 1 |
| Hsu, CC | 1 |
| Huang, A | 1 |
| Chou, SP | 1 |
| Lu, FL | 1 |
| Lee, WT | 1 |
| Hwu, WL | 1 |
| Obanor, O | 1 |
| Osazuwa, HO | 1 |
| Amadasun, JE | 1 |
| Doose, H | 1 |
| Kelly, TH | 1 |
1 trial available for diazepam and Disease Exacerbation
| Article | Year |
|---|---|
Magnesium sulphate for treatment of tetanus in adults.
Topics: Adult; Aged; Autonomic Nervous System Diseases; Cohort Studies; Diazepam; Disease Progression; Femal | 2010 |
11 other studies available for diazepam and Disease Exacerbation
| Article | Year |
|---|---|
Combined diazepam and MK-801 therapy provides synergistic protection from tetramethylenedisulfotetramine-induced tonic-clonic seizures and lethality in mice.
Topics: Animals; Anticonvulsants; Brain Waves; Bridged-Ring Compounds; Central Nervous System; Diazepam; Dis | 2015 |
Bumetanide reduces seizure progression and the development of pharmacoresistant status epilepticus.
Topics: Animals; Anticonvulsants; Brain; Bumetanide; Diazepam; Disease Progression; Drug Resistant Epilepsy; | 2016 |
EEG stages predict treatment response in experimental status epilepticus.
Topics: Analysis of Variance; Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Disease Progressio | 2009 |
Modeling epileptogenesis and temporal lobe epilepsy in a non-human primate.
Topics: Analysis of Variance; Animals; Anticonvulsants; Benzoxazines; Callithrix; Diazepam; Disease Models, | 2011 |
Diazepam reverses the alveolar bone loss and hippocampal interleukin-1beta and interleukin-6 enhanced by conditioned fear stress in ligature-induced periodontal disease in rats.
Topics: Alveolar Bone Loss; Animals; Anti-Anxiety Agents; Conditioning, Operant; Diazepam; Disease Progressi | 2013 |
Hypoxia markers are expressed in interneurons exposed to recurrent seizures.
Topics: Animals; Anticonvulsants; Biomarkers; Cell Hypoxia; Cerebral Cortex; Convulsants; Diazepam; Disease | 2013 |
[Subacute Parkinson's disease after suicide attempt with diazepam].
Topics: Adult; Antiparkinson Agents; Cerebellum; Diazepam; Disease Progression; Drug Overdose; Follow-Up Stu | 2013 |
Poor outcome for neonatal-type nonketotic hyperglycinemia treated with high-dose sodium benzoate and dextromethorphan.
Topics: Brain; Child, Preschool; Chromosome Aberrations; Dextromethorphan; Diazepam; Disease Progression; Di | 2004 |
Ketamine in the management of generalised cephalic tetanus.
Topics: Anticonvulsants; Diazepam; Disease Progression; Female; Humans; Ketamine; Otitis Externa; Otitis Med | 2008 |
Contradictory conclusions about the possible effects of prolonged febrile convulsions.
Topics: Brain; Diazepam; Disease Progression; Electroencephalography; Epilepsies, Myoclonic; Epilepsy, Compl | 1998 |
Conditioning history and the reinforcing effects of drugs: comment on Alessi, Roll, Reilly, and Johanson (2002).
Topics: Anti-Anxiety Agents; Conditioning, Operant; Diazepam; Disease Progression; Humans; Psychomotor Perfo | 2002 |