diazepam has been researched along with Depressive Disorder, Major in 14 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with catatonia who had more than one episode of catatonia and were treated with the lorazepam-diazepam protocol were identified." | 3.83 | Relapses and recurrences of catatonia: 30-case analysis and literature review. ( Huang, TL; Hung, YY; Lin, CC; Tsai, MC, 2016) |
| " In 37 patients with anxiety depression the DST was combined with the diazepam test." | 3.67 | [Use of the dexamethasone test in the differential diagnosis of depressive states]. ( Gordon, OI; Nuller, IuL; Ostroumova, MN, 1986) |
| "Mirtazapine pharmacokinetic (PK) data from patients on long-term treatment for major depression have never been investigated." | 2.71 | Inter- and intraindividual pharmacokinetic variations of mirtazapine and its N-demethyl metabolite in patients treated for major depressive disorder: a 6-month therapeutic drug monitoring study. ( Ahlner, J; Bengtsson, F; Prochazka, J; Reis, M; Sitsen, A, 2005) |
| "001) and benzodiazepine dosage (diazepam equivalent) (HR1." | 1.51 | Risk factors for further sick leave among Japanese workers returning to work after an episode of major depressive disorder: a prospective follow-up study over 1 year. ( Atake, K; Baune, BT; Hori, H; Katsuki, A; Nakamura, J; Yoshimura, R, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (57.14) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Hori, H | 1 |
| Katsuki, A | 1 |
| Atake, K | 1 |
| Yoshimura, R | 1 |
| Nakamura, J | 1 |
| Baune, BT | 1 |
| Osler, M | 1 |
| Jørgensen, MB | 1 |
| Lin, CC | 1 |
| Hung, YY | 1 |
| Tsai, MC | 1 |
| Huang, TL | 1 |
| Taguchi, R | 1 |
| Shikata, K | 1 |
| Furuya, Y | 1 |
| Ino, M | 1 |
| Shin, K | 1 |
| Shibata, H | 1 |
| Yamada, K | 1 |
| Yagi, G | 1 |
| Kanba, S | 1 |
| GOLD, RL | 1 |
| DRIBBEN, IS | 1 |
| DEAN, SR | 1 |
| SMITH, ME | 1 |
| CHASSAN, JB | 1 |
| Reis, M | 1 |
| Prochazka, J | 1 |
| Sitsen, A | 1 |
| Ahlner, J | 1 |
| Bengtsson, F | 1 |
| de Bard, ML | 1 |
| Nuller, IuL | 1 |
| Ostroumova, MN | 1 |
| Gordon, OI | 1 |
| Gundlach, R | 1 |
| Engelhardt, DM | 1 |
| Hankoff, L | 1 |
| Paley, H | 1 |
| Rudorfer, L | 1 |
| Bird, E | 1 |
| Fracchia, J | 1 |
| Sheppard, C | 1 |
| Merlis, S | 1 |
| Wolpowitz, B | 1 |
| Roux, JT | 1 |
4 trials available for diazepam and Depressive Disorder, Major
| Article | Year |
|---|---|
Clinical efficacy of tandospirone augmentation in patients with major depressive disorder: a randomized controlled trial.
Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder, Maj | 2003 |
Inter- and intraindividual pharmacokinetic variations of mirtazapine and its N-demethyl metabolite in patients treated for major depressive disorder: a 6-month therapeutic drug monitoring study.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Anxiety Agents; Antidepressive Agents, | 2005 |
A double-blind outpatient study of diazepam (Valium) and placebo.
Topics: Adolescent; Adult; Ambulatory Care; Anxiety; Clinical Trials as Topic; Depressive Disorder, Major; D | 1966 |
Combination medications in psychiatric treatment: patterns in a group of elderly hospital patients.
Topics: Age Factors; Aged; Amitriptyline; Antidepressive Agents; Antihypertensive Agents; Antisocial Persona | 1971 |
10 other studies available for diazepam and Depressive Disorder, Major
| Article | Year |
|---|---|
Risk factors for further sick leave among Japanese workers returning to work after an episode of major depressive disorder: a prospective follow-up study over 1 year.
Topics: Absenteeism; Adult; Depressive Disorder, Major; Diazepam; Female; Follow-Up Studies; Humans; Japan; | 2019 |
Associations of Benzodiazepines, Z-Drugs, and Other Anxiolytics With Subsequent Dementia in Patients With Affective Disorders: A Nationwide Cohort and Nested Case-Control Study.
Topics: Aged; Aged, 80 and over; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Azabicycl | 2020 |
Relapses and recurrences of catatonia: 30-case analysis and literature review.
Topics: Adolescent; Adult; Antipsychotic Agents; Bipolar Disorder; Catatonia; Clozapine; Depressive Disorder | 2016 |
Selective corticotropin-releasing factor 1 receptor antagonist E2508 has potent antidepressant-like and anxiolytic-like properties in rodent models.
Topics: Acetylcholine; Administration, Oral; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Di | 2016 |
DIAZEPAM THERAPY OF DEPRESSED PATIENTS.
Topics: Bipolar Disorder; Chlordiazepoxide; Depression; Depressive Disorder; Depressive Disorder, Major; Dia | 1964 |
DIAZEPAM AS AN ADJUVANT IN PSYCHOTHERAPY.
Topics: Adolescent; Anxiety; Bipolar Disorder; Depression; Depressive Disorder, Major; Diazepam; Drug Therap | 1964 |
COMPARISONS OF DIAZEPAM, CHLORPROMAZINE AND TRIFLUOPERAZINE IN A DOUBLE-BLIND CLINICAL INVESTIGATION.
Topics: Anxiety; Anxiety Disorders; Biomedical Research; Chlorpromazine; Depression; Depressive Disorder; De | 1964 |
Diazepam withdrawal syndrome: a case with psychosis, seizure, and coma.
Topics: Coma; Depressive Disorder, Major; Diazepam; Epilepsy, Tonic-Clonic; Humans; Male; Middle Aged; Psych | 1979 |
[Use of the dexamethasone test in the differential diagnosis of depressive states].
Topics: 11-Hydroxycorticosteroids; Adolescent; Adult; Aged; Anxiety; Bipolar Disorder; Depression; Depressiv | 1986 |
[Parenteral treatment of depressive diseases].
Topics: Antidepressive Agents; Bipolar Disorder; Dementia; Depression; Depressive Disorder, Major; Desiprami | 1970 |