diazepam has been researched along with Depression, Endogenous in 105 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In summary, the clinical results of this double-blind study clearly show that imipramine, as expected, demonstrated significant antidepressive properties in outpatients suffering from major depressive disorders." | 9.07 | Adinazolam, diazepam, imipramine, and placebo in major depressive disorder: a controlled study. ( Csanalosi, I; Fox, I; Hassman, H; London, J; Rickels, K; Weise, C, 1991) |
| "In summary, the clinical results of this double-blind study clearly show that imipramine, as expected, demonstrated significant antidepressive properties in outpatients suffering from major depressive disorders." | 5.07 | Adinazolam, diazepam, imipramine, and placebo in major depressive disorder: a controlled study. ( Csanalosi, I; Fox, I; Hassman, H; London, J; Rickels, K; Weise, C, 1991) |
| "Two hundred forty-one outpatients with a DSM-III diagnosis of major depressive disorder participated in a six-week double-blind therapeutic trial of alprazolam, diazepam, imipramine hydrochloride, and placebo." | 5.06 | Alprazolam, diazepam, imipramine, and placebo in outpatients with major depression. ( Amsterdam, JD; Chung, HR; Csanalosi, IB; Hurowitz, AM; Kaplan, M; London, J; Rickels, K; Wiseman, K, 1987) |
| "Alprazolam is a triazolobenzodiazepine which is related to diazepam and other 1,4-benzodiazepines, and has a similar pharmacological profile." | 3.75 | Alprazolam: a review of its pharmacodynamic properties and efficacy in the treatment of anxiety and depression. ( Brogden, RN; Dawson, GW; Jue, SG, 1984) |
| "They have definitive properties in neurotic depressions and mixed anxious-depressive states." | 3.75 | [Use of benzodiazepines in the treatment of depression]. ( Escande, M; Girard, M; Granier, F, 1983) |
| " In 37 patients with anxiety depression the DST was combined with the diazepam test." | 3.67 | [Use of the dexamethasone test in the differential diagnosis of depressive states]. ( Gordon, OI; Nuller, IuL; Ostroumova, MN, 1986) |
| " Administration of a standard oral dose of 10 mg diazepam to a series of patients suffering from major depressive disorder produced a significant reduction in men seizure length during ECT compared to length of ECT-induced seizure in those patients when they were benzodiazepine free." | 3.67 | The relationship of concurrent benzodiazepine administration to seizure duration in ECT. ( Deacon, V; Snaith, RP; Standish-Barry, HM, 1985) |
| "A patient developed severe anxiety, moodswing, depression, and thinking disorder 24 hours after abruptly stopping oxazepam, of which he had taken 30 mg 3 times a day for two months, for anxiety and panic attacks." | 3.66 | Abstinence syndrome from therapeutic doses of oxazepam. ( Kulik, AV; Wilbur, R, 1983) |
| "The severity of withdrawal symptoms was measured using the Clinical Institute Withdrawal Assessment-Benzodiazepines (CIWA-B) questionnaire." | 2.71 | Impaired hypothalamic-pituitary-adrenocortical (HPA) system is related to severity of benzodiazepine withdrawal in patients with depression. ( Brunner, H; Friess, E; Holsboer, F; Ising, M; Pedrosa Gil, F; Wichniak, A, 2004) |
| "The aim of this study is to determine whether long-term use (5-20 years) of therapeutic doses of diazepam (5-20 mg/day) in anxious patients (n = 28) is associated with tolerance to its psychomotor and cognitive effects." | 2.67 | Differential acute psychomotor and cognitive effects of diazepam on long-term benzodiazepine users. ( Bernik, MA; Gorenstein, C; Pompéia, S, 1994) |
| "Isocarboxazid was replaced by placebo, using double-blind procedure." | 2.67 | Efficacy of combined antidepressant therapy in resistant neurotic disorder. ( Murphy, S; Tyrer, P, 1990) |
| "Diazepam was a significantly better antidepressant than moclobemide at four week, although not at eight weeks." | 2.66 | Is diazepam an antidepressant? ( Davis, B; Maguire, KP; Schweitzer, I; Tiller, JW, 1989) |
| " No significant correlation was found between the dosage and the serum concentration of imipramine or desipramine." | 2.66 | Comparison of the serum levels in primary non-agitated depressed out-patients treated with imipramine in combination with placebo, diazepam or dixyrazine. ( Feet, PO; Holm, V; Larsen, S; Liden, A; Lillevold, PE; Robak, OH, 1987) |
| " Our study indicates that the discontinuation of diazepam, even when given in moderate dosage over a relatively short period of time, may cause withdrawal reactions in combined antidepressant/diazepam treatment." | 2.66 | Withdrawal reactions to diazepam in combined imipramine/diazepam treatment of primary nonagitated depressed outpatients. ( Feet, PO; Larsen, S; Lillevold, PE; Robak, OH, 1988) |
| "Flupenthixol was significantly more effective in relieving depressive symptoms and somatic symptoms in all four somatic symptom groups considered together." | 2.66 | Neurotic depression accompanied by somatic symptoms: a double-blind comparison of flupenthixol and diazepam in general practice. ( Grillage, M, 1986) |
| " All patients were treated with imipramine (100-200 mg-day) combined with either placebo, diazepam (10 mg/day) or dixyrazine (50 mg/day) for 8 weeks." | 2.66 | A double blind study in out-patients with primary non-agitated depression treated with imipramine in combination with placebo, diazepam or dixyrazine. ( Feet, PO; Larsen, S; Robak, OH, 1985) |
| "Mianserin was shown to be more effective than diazepam in treating symptoms of both depression and anxiety, with significantly more patients in the mianserin group reaching resolution of symptoms in the time period studied." | 2.65 | Management of mixed affective symptoms in primary care: a critical experiment. ( Ancill, RJ; Davey, A; Kennerson, A; Poyser, J, 1984) |
| "Viloxazine was generally well tolerated and side-effects, when they occurred, were generally a mild upper gastro-intestinal disturbance." | 2.64 | A placebo controlled trial of viloxazine with and without tranquillizers in depressive illness. ( Magnus, RV, 1975) |
| "Early identification and treatment of panic disorder might help to avoid unnecessary repeated emergency department visits, and at the same time reduce the associated high risk of suicide and other psychiatric disorders such as depression as well as drug and alcohol abuse." | 2.38 | [Emergency: the internist as psychiatrist]. ( Knüsel, H, 1993) |
| " There were no other adverse events." | 1.36 | The safety and efficacy of benzodiazepine-modified treatments as a special form of unmodified ECT. ( Andrade, C; Bhakta, S; Bhirud, M; Fernandes, P; Mahadeshwar, S; Shah, N, 2010) |
| "The patient has been treated for psoriasis for the past seven years, and two years ago, had to undergo surgery due to bladder carcinoma, followed by a radiotherapy course." | 1.35 | Comorbidity - a troublesome factor in PTSD treatment. ( Dadić-Hero, E; Graovac, M; Medved, P; Ruzić, K; Torić, I, 2009) |
| "Two had organic catatonic disorder and the third organic depressive disorder." | 1.30 | The treatment of stupor associated with MRI evidence of cerebrovascular disease. ( Herzberg, J; Ranger, M; Spear, J, 1997) |
| " It is suggested that the chronic administration of the benzodiazepine may have induced changes in the brain that interfered with ECT." | 1.28 | Do benzodiazepines interfere with the action of electroconvulsive therapy? ( Cohen, SI; Lawton, C, 1992) |
| "Caffeine treatment at the dose 10 mg/kg b." | 1.28 | Validation of aversion towards open space and height as a measure of anxiety in the genetically based animal model of depression. ( Golda, V; Petr, R, 1990) |
| " A tapering schedule was carried out during a 12-day stay in the hospital in which the diazepam dosage was reduced by a fixed quantity every day, corresponding to about ten percent of the initial dosage." | 1.28 | Panic attacks and major depression after discontinuation of long-term diazepam abuse. ( Magni, G; Schifano, F, 1989) |
| " Caution should be exercised in long-term use of benzodiazepines in susceptible individuals." | 1.27 | Delusional depression following benzodiazepine withdrawal. ( Eales, M; Joyce, E; Keshavan, MS; Moodley, P; Yeragani, VK, 1988) |
| "Forty-six patients with various forms of endogenous depression were treated by night sleep deprivation (NSD) which was used as the cardinal method of treatment." | 1.27 | [Sleep deprivation as a method of treating endogenous depression]. ( Fakturovich, AIa; Vovin, RIa, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 55 (52.38) | 18.7374 |
| 1990's | 27 (25.71) | 18.2507 |
| 2000's | 11 (10.48) | 29.6817 |
| 2010's | 10 (9.52) | 24.3611 |
| 2020's | 2 (1.90) | 2.80 |
| Authors | Studies |
|---|---|
| Di Fabio, R | 1 |
| Alvaro, G | 1 |
| Griffante, C | 1 |
| Pizzi, DA | 1 |
| Donati, D | 1 |
| Mattioli, M | 1 |
| Cimarosti, Z | 1 |
| Guercio, G | 1 |
| Marchioro, C | 1 |
| Provera, S | 1 |
| Zonzini, L | 1 |
| Montanari, D | 1 |
| Melotto, S | 1 |
| Gerrard, PA | 1 |
| Trist, DG | 1 |
| Ratti, E | 1 |
| Corsi, M | 1 |
| Osler, M | 1 |
| Jørgensen, MB | 1 |
| Zhao, Y | 1 |
| Lin, Z | 1 |
| Chen, L | 1 |
| Ouyang, L | 1 |
| Gu, L | 1 |
| Chen, F | 1 |
| Zhang, Q | 1 |
| Rahmani, G | 1 |
| Farajdokht, F | 1 |
| Mohaddes, G | 1 |
| Babri, S | 1 |
| Ebrahimi, V | 1 |
| Ebrahimi, H | 1 |
| Nkogho Mengue, PG | 1 |
| Abdous, B | 1 |
| Berbiche, D | 1 |
| Preville, M | 1 |
| Voyer, P | 1 |
| de Rezende, VB | 1 |
| Rosa, DV | 1 |
| Comim, CM | 1 |
| Magno, LA | 1 |
| Rodrigues, AL | 1 |
| Vidigal, P | 1 |
| Jeromin, A | 1 |
| Quevedo, J | 1 |
| Romano-Silva, MA | 1 |
| Papp, M | 1 |
| Gruca, P | 1 |
| Lason-Tyburkiewicz, M | 1 |
| Litwa, E | 1 |
| Willner, P | 1 |
| Vogt, MA | 1 |
| Mallien, AS | 1 |
| Pfeiffer, N | 1 |
| Inta, I | 1 |
| Gass, P | 1 |
| Inta, D | 1 |
| Del Rio, D | 1 |
| Morales, L | 1 |
| Ruiz-Gayo, M | 1 |
| Del Olmo, N | 1 |
| Heijnen, WT | 1 |
| van den Broek, WW | 1 |
| Mulder, PG | 1 |
| Birkenhäger, TK | 1 |
| Wu, SW | 1 |
| Chang, HR | 1 |
| Lai, YR | 1 |
| Lian, JD | 1 |
| Dadić-Hero, E | 1 |
| Torić, I | 1 |
| Ruzić, K | 1 |
| Medved, P | 1 |
| Graovac, M | 1 |
| Matrisciano, F | 1 |
| Nasca, C | 1 |
| Molinaro, G | 1 |
| Riozzi, B | 1 |
| Scaccianoce, S | 1 |
| Raggi, MA | 1 |
| Mercolini, L | 1 |
| Biagioni, F | 1 |
| Mathè, AA | 1 |
| Sanna, E | 1 |
| Maciocco, E | 1 |
| Pignatelli, M | 1 |
| Biggio, G | 1 |
| Nicoletti, F | 1 |
| Shah, N | 1 |
| Mahadeshwar, S | 1 |
| Bhakta, S | 1 |
| Bhirud, M | 1 |
| Fernandes, P | 1 |
| Andrade, C | 1 |
| Diaz, A | 1 |
| Fouilloux, C | 1 |
| Ortiz, S | 1 |
| GSCHLACHT, VE | 1 |
| FELDMAN, PE | 1 |
| TOWLER, ML | 1 |
| COLLARD, J | 1 |
| KERF, J | 1 |
| VILKIN, MI | 1 |
| GOLD, RL | 1 |
| DRIBBEN, IS | 1 |
| FELLNER, CH | 1 |
| SMITH, ME | 1 |
| CHASSAN, JB | 1 |
| GALAMBOS, M | 1 |
| MCCRAY, WE | 1 |
| VENTURI, V | 1 |
| TRAPE, C | 1 |
| BENFATTI, W | 1 |
| Wichniak, A | 1 |
| Brunner, H | 1 |
| Ising, M | 1 |
| Pedrosa Gil, F | 1 |
| Holsboer, F | 1 |
| Friess, E | 1 |
| BLACKMAN, B | 1 |
| Han, C | 1 |
| Li, X | 2 |
| Luo, H | 1 |
| Zhao, X | 1 |
| Tatarczyńska, E | 1 |
| Kłodzińska, A | 1 |
| Stachowicz, K | 1 |
| Chojnacka-Wójcik, E | 1 |
| Terao, T | 1 |
| Hikichi, T | 1 |
| Stemmelin, J | 1 |
| Cohen, C | 1 |
| Terranova, JP | 1 |
| Lopez-Grancha, M | 1 |
| Pichat, P | 1 |
| Bergis, O | 1 |
| Decobert, M | 1 |
| Santucci, V | 1 |
| Françon, D | 1 |
| Alonso, R | 1 |
| Stahl, SM | 1 |
| Keane, P | 1 |
| Avenet, P | 1 |
| Scatton, B | 1 |
| le Fur, G | 1 |
| Griebel, G | 1 |
| Ribeiro, CS | 1 |
| Azevedo, RC | 1 |
| Silva, VF | 1 |
| Botega, NJ | 1 |
| Micale, V | 1 |
| Tamburella, A | 1 |
| Leggio, GM | 1 |
| Mazzola, C | 1 |
| Li Volsi, V | 1 |
| Drago, F | 1 |
| Zung, WW | 1 |
| Daniel, JT | 1 |
| King, RE | 1 |
| Moore, DT | 1 |
| Nuller, JL | 1 |
| Tochilov, VA | 1 |
| Shirokov, VD | 1 |
| Greenblatt, DJ | 3 |
| Shader, RI | 1 |
| Abernethy, DR | 1 |
| Dawson, GW | 1 |
| Jue, SG | 1 |
| Brogden, RN | 1 |
| Escande, M | 1 |
| Granier, F | 1 |
| Girard, M | 1 |
| Olajide, D | 1 |
| Lader, M | 1 |
| Ancill, RJ | 1 |
| Poyser, J | 1 |
| Davey, A | 1 |
| Kennerson, A | 1 |
| Post, RM | 1 |
| Uhde, TW | 1 |
| Atri, PB | 1 |
| Julius, DA | 1 |
| Gray, EG | 1 |
| Pearlman, T | 1 |
| Abou-Saleh, MT | 1 |
| Merry, J | 1 |
| Coppen, A | 1 |
| Friedman, MJ | 1 |
| Stolk, JM | 1 |
| Harris, PQ | 1 |
| Cooper, TB | 1 |
| Ramesar, S | 1 |
| McCall, M | 1 |
| Wilbur, R | 1 |
| Kulik, AV | 1 |
| Hyde, C | 1 |
| Goldberg, D | 1 |
| Pinder, RM | 1 |
| Fink, M | 1 |
| Boleloutskiĭ, Z | 1 |
| D'Elia, G | 1 |
| Good, WV | 1 |
| Dubovsky, SL | 1 |
| Gorenstein, C | 1 |
| Bernik, MA | 1 |
| Pompéia, S | 1 |
| Krupitsky, EM | 1 |
| Burakov, AM | 1 |
| Ivanov, VB | 1 |
| Krandashova, GF | 1 |
| Lapin, IP | 1 |
| Tyrer, P | 5 |
| Seivewright, N | 4 |
| Ferguson, B | 4 |
| Murphy, S | 4 |
| Johnson, AL | 3 |
| Knüsel, H | 1 |
| Petty, F | 1 |
| Trivedi, MH | 1 |
| Fulton, M | 1 |
| Rush, AJ | 1 |
| Hänselmann, H | 1 |
| Hänselmann, S | 1 |
| Thomas, H | 1 |
| Mörchen, G | 1 |
| Spear, J | 1 |
| Ranger, M | 1 |
| Herzberg, J | 1 |
| Cannizzaro, C | 1 |
| Cannizzaro, E | 1 |
| Gagliano, M | 1 |
| Mineo, A | 1 |
| Broderick, PA | 1 |
| Hope, O | 1 |
| Jeannot, P | 1 |
| Zitman, FG | 1 |
| Couvée, JE | 1 |
| Kabes, J | 1 |
| Dostal, T | 1 |
| Gullick, EL | 1 |
| King, LJ | 1 |
| Magnus, RV | 1 |
| Sills, LM | 1 |
| Popkin, MK | 1 |
| Najarian, JS | 1 |
| Tyrer, J | 1 |
| Cohen, SI | 1 |
| Lawton, C | 1 |
| Khaspekova, NB | 1 |
| Loseva, MM | 1 |
| Kuterman, EM | 1 |
| Sczesni, B | 1 |
| Becker, H | 1 |
| Schröder, J | 1 |
| Bittkau, S | 1 |
| von Baumgarten, F | 1 |
| Truong, DD | 1 |
| Przuntek, H | 1 |
| Rickels, K | 4 |
| London, J | 2 |
| Fox, I | 1 |
| Hassman, H | 1 |
| Csanalosi, I | 1 |
| Weise, C | 1 |
| Benazzi, F | 1 |
| Schweizer, E | 2 |
| Case, WG | 2 |
| Golda, V | 1 |
| Petr, R | 1 |
| Mitchell, P | 1 |
| Smythe, G | 1 |
| Darling, C | 2 |
| Brothwell, J | 2 |
| Kingdon, D | 2 |
| Lazarus, A | 1 |
| Swartz, CM | 1 |
| Yeragani, VK | 2 |
| Pohl, R | 1 |
| Balon, R | 1 |
| Ramesh, C | 1 |
| Glitz, D | 1 |
| Tiller, J | 2 |
| Davies, B | 2 |
| Schweitzer, I | 3 |
| Maguire, K | 2 |
| Schifano, F | 1 |
| Magni, G | 1 |
| Tiller, JW | 1 |
| Maguire, KP | 1 |
| Davis, B | 1 |
| O'Connor, WT | 1 |
| Earley, B | 1 |
| Leonard, BE | 1 |
| Tibilova, AU | 1 |
| Alimova, RA | 1 |
| Feet, PO | 3 |
| Larsen, S | 3 |
| Lillevold, PE | 2 |
| Liden, A | 1 |
| Holm, V | 1 |
| Robak, OH | 3 |
| Barczak, P | 1 |
| Gregory, S | 1 |
| Wetzel, H | 1 |
| Heuser, I | 1 |
| Benkert, O | 1 |
| Keshavan, MS | 1 |
| Moodley, P | 1 |
| Eales, M | 1 |
| Joyce, E | 1 |
| Chung, HR | 1 |
| Csanalosi, IB | 1 |
| Hurowitz, AM | 1 |
| Wiseman, K | 1 |
| Kaplan, M | 1 |
| Amsterdam, JD | 1 |
| Bergman, U | 1 |
| Griffiths, RR | 1 |
| Ananth, J | 1 |
| Otani, K | 1 |
| Nordin, C | 1 |
| Bertilsson, L | 1 |
| Nuller, IuL | 1 |
| Ostroumova, MN | 1 |
| Gordon, OI | 1 |
| Grillage, M | 1 |
| Vovin, RIa | 1 |
| Fakturovich, AIa | 1 |
| Standish-Barry, HM | 1 |
| Deacon, V | 1 |
| Snaith, RP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Implementation Strategies Aimed at a Simple Patient-directed Intervention to Reduce Long-term Use of Benzodiazepines in Dutch Community Pharmacies[NCT00268775] | 20,000 participants | Interventional | 2005-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for diazepam and Depression, Endogenous
| Article | Year |
|---|---|
Drug therapy. Current status of benzodiazepines.
Topics: Alcoholic Beverages; Alcoholism; Anesthetics; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Bone Di | 1983 |
Alprazolam: a review of its pharmacodynamic properties and efficacy in the treatment of anxiety and depression.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Benzodiazepines; | 1984 |
[Use of benzodiazepines in the treatment of depression].
Topics: Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Clinical Trials as Topic; Depres | 1983 |
Treatment of mood disorders with antiepileptic medications: clinical and theoretical implications.
Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Clonazepam; Depressive D | 1983 |
Mianserin.
Topics: Animals; Antidepressive Agents, Tricyclic; Cardiovascular Diseases; Central Nervous System; Depressi | 1982 |
[Emergency: the internist as psychiatrist].
Topics: Crisis Intervention; Depressive Disorder; Diagnosis, Differential; Diazepam; Emergencies; Family Pra | 1993 |
Benzodiazepines as antidepressants: does GABA play a role in depression?
Topics: Alprazolam; Antidepressive Agents; Benzodiazepines; Chlordiazepoxide; Depressive Disorder; Diazepam; | 1995 |
Clomipramine: an antiobsessive drug.
Topics: Anxiety; Behavior Therapy; Clinical Trials as Topic; Clomipramine; Compulsive Behavior; Depressive D | 1986 |
29 trials available for diazepam and Depression, Endogenous
| Article | Year |
|---|---|
Prevalence of trait anxiety in a sample of depressed inpatients and its influence on response to antidepressants.
Topics: Adult; Aged; Antidepressive Agents; Anxiety; Depressive Disorder; Diazepam; Double-Blind Method; Fem | 2010 |
Open trial study of a combined antidepressant (amitryptiline, perphenazine, diazepam) versus fluoxetine or imipramine in ambulatory depressed patients.
Topics: Adolescent; Adult; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, | 2002 |
Impaired hypothalamic-pituitary-adrenocortical (HPA) system is related to severity of benzodiazepine withdrawal in patients with depression.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Benzodiazepines; | 2004 |
A comparison of prazepam, diazepam, lorazepam and placebo in anxious outpatients in non-psychiatric private practices.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Depressive Disorder; Diazepam; Doub | 1981 |
Alprazolam: a review of its pharmacodynamic properties and efficacy in the treatment of anxiety and depression.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Benzodiazepines; | 1984 |
[Use of benzodiazepines in the treatment of depression].
Topics: Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Clinical Trials as Topic; Depres | 1983 |
Management of mixed affective symptoms in primary care: a critical experiment.
Topics: Adolescent; Adult; Aged; Anxiety Disorders; Clinical Trials as Topic; Depressive Disorder; Diazepam; | 1984 |
Treatment of mood disorders with antiepileptic medications: clinical and theoretical implications.
Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Clonazepam; Depressive D | 1983 |
Differential acute psychomotor and cognitive effects of diazepam on long-term benzodiazepine users.
Topics: Adult; Anxiety Disorders; Cognition; Depressive Disorder; Diazepam; Dose-Response Relationship, Drug | 1994 |
Baclofen administration for the treatment of affective disorders in alcoholic patients.
Topics: Administration, Oral; Adult; Alcoholism; Amitriptyline; Anxiety Disorders; Baclofen; Blood Platelets | 1993 |
The Nottingham study of neurotic disorder. Effect of personality status on response to drug treatment, cognitive therapy and self-help over two years.
Topics: Adult; Anxiety Disorders; Cognitive Behavioral Therapy; Depressive Disorder; Diazepam; Dothiepin; Fe | 1993 |
Chronic benzodiazepine use in general practice patients with depression: an evaluation of controlled treatment and taper-off: report on behalf of the Dutch Chronic Benzodiazepine Working Group.
Topics: Adult; Aged; Aged, 80 and over; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Depre | 2001 |
A placebo controlled trial of viloxazine with and without tranquillizers in depressive illness.
Topics: Depressive Disorder; Diazepam; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; | 1975 |
The general neurotic syndrome: a coaxial diagnosis of anxiety, depression and personality disorder.
Topics: Adjustment Disorders; Anxiety Disorders; Cognitive Behavioral Therapy; Depressive Disorder; Diazepam | 1992 |
[Evaluation of the effectiveness of drug therapy of autonomic paroxysms in relation to the variability of cardiac rhythm].
Topics: Adult; Anxiety Disorders; Autonomic Nervous System Diseases; Depressive Disorder; Diazepam; Heart Ra | 1991 |
Adinazolam, diazepam, imipramine, and placebo in major depressive disorder: a controlled study.
Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Depressive Disorder; Diazepam; D | 1991 |
Carbamazepine treatment in patients discontinuing long-term benzodiazepine therapy. Effects on withdrawal severity and outcome.
Topics: Benzodiazepines; Carbamazepine; Depressive Disorder; Diazepam; Double-Blind Method; Female; Humans; | 1991 |
The Nottingham Study of Neurotic Disorder: relationship between personality status and symptoms.
Topics: Anxiety Disorders; Behavior Therapy; Clinical Trials as Topic; Cognitive Behavioral Therapy; Depress | 1990 |
Long-term therapeutic use of benzodiazepines. I. Effects of abrupt discontinuation.
Topics: Ambulatory Care; Anxiety Disorders; Benzodiazepines; Dependent Personality Disorder; Depressive Diso | 1990 |
Efficacy of combined antidepressant therapy in resistant neurotic disorder.
Topics: Adult; Amitriptyline; Anxiety Disorders; Clinical Trials as Topic; Depressive Disorder; Diazepam; Do | 1990 |
Treatment of atypical depression with moclobemide: a sequential double controlled study.
Topics: Adult; Aged; Antidepressive Agents; Benzamides; Clinical Trials as Topic; Depressive Disorder; Diaze | 1989 |
Is diazepam an antidepressant?
Topics: Adult; Antidepressive Agents; Anxiety Disorders; Arousal; Benzamides; Depressive Disorder; Diazepam; | 1989 |
Comparison of the serum levels in primary non-agitated depressed out-patients treated with imipramine in combination with placebo, diazepam or dixyrazine.
Topics: Adult; Antipsychotic Agents; Clinical Trials as Topic; Depressive Disorder; Desipramine; Diazepam; D | 1987 |
The Nottingham study of neurotic disorder: comparison of drug and psychological treatments.
Topics: Adult; Aged; Analysis of Variance; Anxiety Disorders; Behavior Therapy; Clinical Trials as Topic; Co | 1988 |
Withdrawal reactions to diazepam in combined imipramine/diazepam treatment of primary nonagitated depressed outpatients.
Topics: Clinical Trials as Topic; Depressive Disorder; Desipramine; Diazepam; Double-Blind Method; Drug Ther | 1988 |
Alprazolam, diazepam, imipramine, and placebo in outpatients with major depression.
Topics: Adult; Alprazolam; Ambulatory Care; Clinical Trials as Topic; Depressive Disorder; Diazepam; Double- | 1987 |
Clomipramine: an antiobsessive drug.
Topics: Anxiety; Behavior Therapy; Clinical Trials as Topic; Clomipramine; Compulsive Behavior; Depressive D | 1986 |
Neurotic depression accompanied by somatic symptoms: a double-blind comparison of flupenthixol and diazepam in general practice.
Topics: Adult; Aged; Depressive Disorder; Diazepam; Double-Blind Method; Family Practice; Flupenthixol; Huma | 1986 |
A double blind study in out-patients with primary non-agitated depression treated with imipramine in combination with placebo, diazepam or dixyrazine.
Topics: Adult; Clinical Trials as Topic; Depressive Disorder; Diazepam; Double-Blind Method; Drug Therapy, C | 1985 |
72 other studies available for diazepam and Depression, Endogenous
| Article | Year |
|---|---|
Discovery and biological characterization of (2R,4S)-1'-acetyl-N-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl}-2-(4-fluoro-2-methylphenyl)-N-methyl-4,4'-bipiperidine-1-carboxamide as a new potent and selective neurokinin 1 (NK1) receptor antagonist clini
Topics: Animals; Behavior, Animal; Brain; CHO Cells; Cricetinae; Cricetulus; Depressive Disorder; Drug Disco | 2011 |
Associations of Benzodiazepines, Z-Drugs, and Other Anxiolytics With Subsequent Dementia in Patients With Affective Disorders: A Nationwide Cohort and Nested Case-Control Study.
Topics: Aged; Aged, 80 and over; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Azabicycl | 2020 |
Hippocampal astrocyte atrophy in a mouse depression model induced by corticosterone is reversed by fluoxetine instead of benzodiazepine diazepam.
Topics: Animals; Antidepressive Agents; Astrocytes; Atrophy; Corticosterone; Depressive Disorder; Diazepam; | 2018 |
Garlic (
Topics: Animals; Antidepressive Agents; Antioxidants; Anxiety; Brain; Depressive Disorder; Diabetes Mellitus | 2020 |
[Benzodiazepine dependence and the risk of depression and anxiety disorders: seniors' health study].
Topics: Aged; Aged, 80 and over; Anxiety Disorders; Benzodiazepines; Cohort Studies; Cross-Sectional Studies | 2014 |
NCS-1 deficiency causes anxiety and depressive-like behavior with impaired non-aversive memory in mice.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety Disorders; Avoidance Learnin | 2014 |
Effects of chronic mild stress on the development of drug dependence in rats.
Topics: Animals; Chronic Disease; Citalopram; Depressive Disorder; Diazepam; Disease Models, Animal; Flumaze | 2014 |
Minocycline does not evoke anxiolytic and antidepressant-like effects in C57BL/6 mice.
Topics: Animals; Anti-Anxiety Agents; Anti-Bacterial Agents; Antidepressive Agents; Anxiety Disorders; Depre | 2016 |
Effect of high-fat diets on mood and learning performance in adolescent mice.
Topics: Affect; Animals; Anti-Anxiety Agents; Depressive Disorder; Diazepam; Diet, High-Fat; Exploratory Beh | 2016 |
Non-life-threatening leukopenia in a renal transplant recipient with acute overdose of mycophenolate mofetil.
Topics: Adult; Antidepressive Agents; Benzodiazepines; Charcoal; Cholestyramine Resin; Depressive Disorder; | 2008 |
Comorbidity - a troublesome factor in PTSD treatment.
Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents; Combat Disorders; Combined Modality Therapy; Como | 2009 |
Enhanced expression of the neuronal K+/Cl- cotransporter, KCC2, in spontaneously depressed Flinders Sensitive Line rats.
Topics: Animals; Central Nervous System Agents; Cerebellum; Cerebral Cortex; Depressive Disorder; Diazepam; | 2010 |
The safety and efficacy of benzodiazepine-modified treatments as a special form of unmodified ECT.
Topics: Adolescent; Adult; Benzodiazepines; Child; Depressive Disorder; Diazepam; Electroconvulsive Therapy; | 2010 |
[Ambulant treatment of mental patients with the new psychopharmacon Valium "Roche"].
Topics: Depression; Depressive Disorder; Diazepam; Humans; Mental Disorders; Mentally Ill Persons; Neurotic | 1963 |
An analysis of the efficacy of diazepam.
Topics: Chlordiazepoxide; Depression; Depressive Disorder; Diazepam; Schizophrenia; Tranquilizing Agents | 1962 |
The clinical use of diazepam in anxiety states and depressions.
Topics: Anxiety; Anxiety Disorders; Depression; Depressive Disorder; Diazepam; Tranquilizing Agents | 1962 |
[A NEW ANXIOLYTIC AGENT: RO 5-2807 OR DIAZEPAM].
Topics: Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Depression; Depressive Disorder; Diazepam; Humans; | 1963 |
COMPARATIVE CHEMOTHERAPEUTIC TRIAL IN TREATMENT OF CHRONIC BORDERLINE PATIENTS.
Topics: Antidepressive Agents; Anxiety; Benactyzine; Depression; Depressive Disorder; Diazepam; Humans; Mepr | 1964 |
DIAZEPAM THERAPY OF DEPRESSED PATIENTS.
Topics: Bipolar Disorder; Chlordiazepoxide; Depression; Depressive Disorder; Depressive Disorder, Major; Dia | 1964 |
EARLY RECOGNITION OF DEPRESSION.
Topics: Amitriptyline; Amphetamine; Amphetamines; Barbiturates; Benactyzine; Chlordiazepoxide; Deanol; Depre | 1964 |
COMPARISONS OF DIAZEPAM, CHLORPROMAZINE AND TRIFLUOPERAZINE IN A DOUBLE-BLIND CLINICAL INVESTIGATION.
Topics: Anxiety; Anxiety Disorders; Biomedical Research; Chlorpromazine; Depression; Depressive Disorder; De | 1964 |
THE LONG-TERM USE OF VALIUM.
Topics: Depression; Depressive Disorder; Diazepam; Drug Therapy; Epilepsy; Intellectual Disability | 1965 |
DIAZEPAM AND COMBINED TREATMENT IN OUTPATIENTS WITH DEPRESSIVE SYNDROMES.
Topics: Combined Modality Therapy; Depression; Depressive Disorder; Diazepam; Drug Therapy; Humans; Outpatie | 1965 |
[A NEW PSYCHOTROPIC AGENT--DIAZEPAM--IN THE TREATMENT OF DEPRESSION].
Topics: Depression; Depressive Disorder; Diazepam; Drug Therapy; Psychotropic Drugs; Toxicology | 1965 |
THE ADJUNCTIVE ROLE OF DIAZEPAM IN THE TREATMENT OF DEPRESSION.
Topics: Antidepressive Agents; Depression; Depressive Disorder; Diazepam; Humans; Psychotherapy; Tranquilizi | 1963 |
Clinical study on electro-acupuncture treatment for 30 cases of mental depression.
Topics: Acupuncture Therapy; Adolescent; Adult; Depression; Depressive Disorder; Diazepam; Electroacupunctur | 2004 |
Effects of a selective 5-HT1B receptor agonist and antagonists in animal models of anxiety and depression.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Behavior, Animal; Benzamide | 2004 |
Serotonin syndrome in a case of depression with various somatic symptoms: the difficulty in differential diagnosis.
Topics: Aged; Akathisia, Drug-Induced; Anxiety; Depressive Disorder; Diagnosis, Differential; Diazepam; Dysa | 2007 |
Stimulation of the beta3-Adrenoceptor as a novel treatment strategy for anxiety and depressive disorders.
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Aggression; Animals; Anti-Anxiety Age | 2008 |
Chronic use of diazepam in primary healthcare centers: user profile and usage pattern.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Depressive Disorder; Diazepam; Drug Utilization; Female; Hum | 2007 |
Behavioral effects of saredutant, a tachykinin NK2 receptor antagonist, in experimental models of mood disorders under basal and stress-related conditions.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Behavior, Animal; Benzamide | 2008 |
Pills for nerves.
Topics: Amitriptyline; Anxiety Disorders; Depressive Disorder; Diazepam; Drug Therapy, Combination; Humans; | 1980 |
The use of a diazepam test for the study of depressive state structure and for choice of therapy.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Bipolar Disorder; | 1982 |
Depression following withdrawal from long-term benzodiazepine use: a report of four cases.
Topics: Adult; Anti-Anxiety Agents; Depressive Disorder; Diazepam; Female; Flurazepam; Humans; Lorazepam; Ma | 1984 |
Maprotiline hydrochloride associated with a clinical state of catatonic stupor and epileptic encephalogram.
Topics: Anthracenes; Catatonia; Depressive Disorder; Diazepam; Drug Therapy, Combination; Electroencephalogr | 1984 |
Severe depression: a patient's thoughts.
Topics: Depressive Disorder; Diazepam; Electroconvulsive Therapy; Humans; Lithium; Male; Mianserin; Middle A | 1983 |
Withdrawal symptoms after long-term treatment with flurazepam.
Topics: Anxiety Disorders; Depressive Disorder; Diazepam; Flurazepam; Humans; Sleep Initiation and Maintenan | 1984 |
Dexamethasone suppression test in alcoholism.
Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Depressive Disorder; Dexamethasone; Diazepam; Female | 1984 |
Serum dopamine-beta-hydroxylase activity in depression and anxiety.
Topics: Adult; Aged; Alprazolam; Anxiety; Anxiety Disorders; Benzodiazepines; Depression; Depressive Disorde | 1984 |
Coping with the negative therapeutic response in psychosocial problems in family medicine.
Topics: Adult; Dependency, Psychological; Depressive Disorder; Diazepam; Family Practice; Family Therapy; Fe | 1983 |
Abstinence syndrome from therapeutic doses of oxazepam.
Topics: Adult; Anxiety; Depression; Depressive Disorder; Diazepam; Fasciculation; Fear; Humans; Male; Oxazep | 1983 |
Labelling and drug effects in the treatment of neurotic affective disorders: an experimental investigation.
Topics: Adolescent; Adult; Aged; Anxiety Disorders; Depressive Disorder; Diazepam; Double-Blind Method; Fema | 1983 |
[Psychopharmacologic approach to studying various problems in slowly progressive schizophrenia].
Topics: Depressive Disorder; Diagnosis, Differential; Diazepam; Dibenzothiepins; Dothiepin; Humans; Methotri | 1982 |
Benzodiazepines and effectiveness of ECT.
Topics: Depressive Disorder; Diazepam; Electroconvulsive Therapy; Humans | 1982 |
Pseudodementia masking substance abuse and depression.
Topics: Depressive Disorder; Diagnosis, Differential; Diazepam; Factitious Disorders; Female; Humans; Middle | 1982 |
[Tuberculous meningitis].
Topics: Depressive Disorder; Diagnosis, Differential; Diazepam; Female; Humans; Middle Aged; Neurocognitive | 1996 |
[Benzodiazepine withdrawal syndrome in low dose dependency].
Topics: Anti-Anxiety Agents; Anxiety Disorders; Chlordiazepoxide; Depressive Disorder; Diazepam; Dose-Respon | 1996 |
The treatment of stupor associated with MRI evidence of cerebrovascular disease.
Topics: Aged; Anticonvulsants; Antidepressive Agents; Carbamazepine; Catatonia; Cerebrovascular Disorders; C | 1997 |
Locomotor and antidepressant-like effects of 5-HT(1A) agonist LY 228729 in prenatally benzodiazepine-exposed rats.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Antidepressive Agents; Depressive Disorder; Diazepam; Ergo | 1998 |
Mechanism of triazolo-benzodiazepine and benzodiazepine action in anxiety and depression: behavioral studies with concomitant in vivo CA1 hippocampal norepinephrine and serotonin release detection in the behaving animal.
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Depressive Disorder; Diazepam; Exploratory Behavior | 1998 |
Beta-adrenergic blocking drugs versus diazepam in the treatment of anxious-depressive syndrome.
Topics: Adrenergic beta-Antagonists; Anxiety Disorders; Depressive Disorder; Diazepam; Humans | 1977 |
Appropriateness of drugs prescribed by primary care physicians for depressed outpatients.
Topics: Adult; Depressive Disorder; Diazepam; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; | 1979 |
Elective removal of a transplanted organ.
Topics: Adult; Alcohol Withdrawal Delirium; Cadaver; Depressive Disorder; Diazepam; Humans; Kidney; Male; Or | 1992 |
Do benzodiazepines interfere with the action of electroconvulsive therapy?
Topics: Aged; Anxiety Disorders; Combined Modality Therapy; Depressive Disorder; Diazepam; Electroconvulsive | 1992 |
[Diagnostic and therapeutic aspects of neuroleptic malignant syndrome based on 12 cases].
Topics: Adult; Amantadine; Antipsychotic Agents; Bromocriptine; Dantrolene; Depressive Disorder; Diazepam; D | 1991 |
Depressive stupor treated with intramuscular chlordesmethyldiazepam.
Topics: Anti-Anxiety Agents; Arousal; Benzodiazepines; Depressive Disorder; Diazepam; Female; Humans; Inject | 1990 |
Validation of aversion towards open space and height as a measure of anxiety in the genetically based animal model of depression.
Topics: Animals; Anxiety; Behavior, Animal; Caffeine; Depressive Disorder; Diazepam; Disease Models, Animal; | 1990 |
Hormonal responses to fenfluramine in depressed and control subjects.
Topics: Adult; Bipolar Disorder; Depressive Disorder; Diazepam; Female; Fenfluramine; Humans; Hydrocortisone | 1990 |
Rhabdomyolysis in a depressed patient following overdose with combined drug therapy and alcohol.
Topics: Adult; Alcoholic Intoxication; Depressive Disorder; Diazepam; Doxepin; Fluoxetine; Humans; Male; Rha | 1990 |
Electroconvulsive therapy emergence agitation and succinylcholine dose.
Topics: Adult; Akathisia, Drug-Induced; Bipolar Disorder; Depressive Disorder; Diazepam; Dose-Response Relat | 1990 |
Increased serum total cholesterol to HDL-cholesterol ratio after imipramine.
Topics: Adult; Anxiety Disorders; Cholesterol; Cholesterol, HDL; Depressive Disorder; Diazepam; Fear; Female | 1990 |
Is diazepam an antidepressant?
Topics: Depressive Disorder; Diazepam; Dose-Response Relationship, Drug; Humans | 1990 |
Panic attacks and major depression after discontinuation of long-term diazepam abuse.
Topics: Adult; Anxiety; Clomipramine; Depressive Disorder; Diazepam; Fear; Female; Humans; Panic; Substance | 1989 |
Antidepressant properties of the triazolobenzodiazepines alprazolam and adinazolam: studies on the olfactory bulbectomized rat model of depression.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Biogenic Amines; B | 1985 |
[Problem of transient dementias of old age (clinico-diagnostic aspect)].
Topics: Aged; Amphetamine; Anxiety; Central Nervous System Stimulants; Dementia; Depressive Disorder; Diagno | 1985 |
Benzodiazepines for catatonic symptoms, stupor, and mutism.
Topics: Anti-Anxiety Agents; Benzodiazepines; Catatonia; Depressive Disorder; Diazepam; Female; Flumazenil; | 1988 |
Delusional depression following benzodiazepine withdrawal.
Topics: Adult; Anxiety Disorders; Delusions; Depressive Disorder; Diazepam; Female; Humans; Lorazepam; Male; | 1988 |
Relative abuse of diazepam and oxazepam: prescription forgeries and theft/loss reports in Sweden.
Topics: Cross-Sectional Studies; Depressive Disorder; Diazepam; Drug and Narcotic Control; Drug Prescription | 1986 |
No interaction of diazepam on amitriptyline disposition in depressed patients.
Topics: Adult; Amitriptyline; Depressive Disorder; Diazepam; Drug Interactions; Female; Humans; Middle Aged; | 1987 |
[Use of the dexamethasone test in the differential diagnosis of depressive states].
Topics: 11-Hydroxycorticosteroids; Adolescent; Adult; Aged; Anxiety; Bipolar Disorder; Depression; Depressiv | 1986 |
[Sleep deprivation as a method of treating endogenous depression].
Topics: Adult; Amitriptyline; Anxiety; Depersonalization; Depressive Disorder; Diazepam; Female; Humans; Imi | 1985 |
The relationship of concurrent benzodiazepine administration to seizure duration in ECT.
Topics: Adult; Combined Modality Therapy; Depressive Disorder; Diazepam; Electroconvulsive Therapy; Female; | 1985 |