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diazepam and Dementia

diazepam has been researched along with Dementia in 28 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.

Research Excerpts

ExcerptRelevanceReference
"Thioridazine was compared with placebo or diazepam or both in 610 elderly, nonpsychotic inpatients in geriatric wards of state hospitals or nursing homes."2.65Multicenter study comparing thioridazine with diazepam and placebo in elderly, nonpsychotic patients with emotional and behavioral disorders. ( Stotsky, B, 1984)
" By measuring the brain function using computer period analysis of cerebral biopotentials, dose-efficacy relations were found (in the range of 25-75 mcg) which suggest the bioavailability of LHM at the CNS level."2.64Prediction of psychotropic properties of lisuride hydrogen maleate by quantitative pharmaco-electroencephalogram. ( Akpinar, S; Herrmann, WM; Itil, TM, 1975)
"We report one Chinese patient with neurosyphilis exhibiting periodic lateralized epileptiform discharges (PLEDs) in the electroencephalogram (EEG)."1.40A patient with progressive cognitive decline and periodic abnormal waves in EEG: PLEDs of neurosyphilis or PSDs of Creutzfeldt-Jakob disease? ( Chu, F; Cui, L; Lv, Y; Meng, H; Wang, Z, 2014)
"Dementia is one of the age related mental problems and a characteristic symptom of various neurodegenerative disorders including Alzheimer's disease."1.33Evaluation of nootropic potential of Ocimum sanctum Linn. in mice. ( Joshi, H; Parle, M, 2006)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199017 (60.71)18.7374
1990's4 (14.29)18.2507
2000's2 (7.14)29.6817
2010's3 (10.71)24.3611
2020's2 (7.14)2.80

Authors

AuthorsStudies
Bucki, A2
Marcinkowska, M2
Śniecikowska, J2
Więckowski, K1
Pawłowski, M2
Głuch-Lutwin, M2
Gryboś, A1
Siwek, A2
Pytka, K2
Jastrzębska-Więsek, M2
Partyka, A2
Wesołowska, A2
Mierzejewski, P2
Kołaczkowski, M2
Zagórska, A1
Jamrozik, M1
Jakubczyk, M1
Osler, M1
Jørgensen, MB1
Vilibić, M1
Jukić, V1
Vidović, A1
Brecić, P1
Lv, Y1
Chu, F1
Meng, H1
Wang, Z1
Cui, L1
DELEMOS, GP1
CLEMENT, WR1
NICKELS, E1
Suaudeau, C1
do-Rego, JC1
Costentin, J1
Joshi, H1
Parle, M1
Bánki, CM1
Werner, V1
Diehl, LW1
Stotsky, B1
Both, R1
Mühlau, G1
Neumann, J1
Sperschneider, H1
Stein, G1
Busch, KT1
Schulz, H1
Anderer, P1
Barbanoj, MJ1
Saletu, B1
Semlitsch, HV1
Dressler, C1
Franke, KP1
Herzig, M1
Nagel, U1
Robbins, TW1
Semple, J1
Kumar, R1
Truman, MI1
Shorter, J1
Ferraro, A1
Fox, B1
McKay, G1
Matthews, K1
Yonou, H1
Kagawa, H1
Oda, A1
Nagano, M1
Gakiya, M1
Niimura, K1
Hatano, T1
Ogawa, Y1
Taclob, L1
Needle, M1
Reid, RW1
Youngs, DD1
Covington, JS1
Itil, TM1
Herrmann, WM1
Akpinar, S1
Tibilova, AU1
Alimova, RA1
Rennert, H1
Bergmann, K1
Scharfetter, C1
Schmoigl, S1
Webb, WL1
Helmchen, H1
Wolpowitz, B1
Roux, JT1

Reviews

1 review available for diazepam and Dementia

ArticleYear
[The state of psychopharmacotherapy in geriatrics 2].
    Therapie der Gegenwart, 1980, Volume: 119, Issue:12

    Topics: Actihaemyl; Aged; Amitriptyline; Bencyclane; Cerebrovascular Circulation; Clorazepate Dipotassium; D

1980

Trials

6 trials available for diazepam and Dementia

ArticleYear
Comparative study with Grandaxin and diazepam in alcohol withdrawal syndrome and gerontopsychiatric diseases.
    Therapia Hungarica (English edition), 1983, Volume: 31, Issue:3

    Topics: Aged; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Dementia; Diazepam; Ethanol; F

1983
Multicenter study comparing thioridazine with diazepam and placebo in elderly, nonpsychotic patients with emotional and behavioral disorders.
    Clinical therapeutics, 1984, Volume: 6, Issue:4

    Topics: Affective Symptoms; Aged; Clinical Trials as Topic; Dementia; Diazepam; Double-Blind Method; Humans;

1984
Restriction to a limited set of EEG-target variables may lead to misinterpretation of pharmaco-EEG results.
    Neuropsychobiology, 1993, Volume: 27, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain; Brain Mapping; Buspirone; Dementia; Diazepam; Dou

1993
Effects of scopolamine on delayed-matching-to-sample and paired associates tests of visual memory and learning in human subjects: comparison with diazepam and implications for dementia.
    Psychopharmacology, 1997, Volume: 134, Issue:1

    Topics: Adult; Anti-Anxiety Agents; Blood Pressure; Dementia; Diazepam; Dose-Response Relationship, Drug; He

1997
Alleviating agitation, apprehension, and related symptoms in geriatric patients: A double-blind comparison of a phenothiazine and a benzodiazepien.
    Southern medical journal, 1975, Volume: 68, Issue:6

    Topics: Aged; Anxiety; Clinical Trials as Topic; Dementia; Depression; Diazepam; Drug Evaluation; Female; Hu

1975
Prediction of psychotropic properties of lisuride hydrogen maleate by quantitative pharmaco-electroencephalogram.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:1-2

    Topics: Adolescent; Adult; Aged; Biological Availability; Child; Child, Preschool; Clinical Trials as Topic;

1975

Other Studies

21 other studies available for diazepam and Dementia

ArticleYear
Novel 3-(1,2,3,6-Tetrahydropyridin-4-yl)-1H-indole-Based Multifunctional Ligands with Antipsychotic-Like, Mood-Modulating, and Procognitive Activity.
    Journal of medicinal chemistry, 2017, 09-14, Volume: 60, Issue:17

    Topics: Affect; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Dementia; Dopamine Agonist

2017
Multifunctional 6-fluoro-3-[3-(pyrrolidin-1-yl)propyl]-1,2-benzoxazoles targeting behavioral and psychological symptoms of dementia (BPSD).
    European journal of medicinal chemistry, 2020, Apr-01, Volume: 191

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzoxazoles; Dementia; Dizocilpine Maleate; Dose-R

2020
Associations of Benzodiazepines, Z-Drugs, and Other Anxiolytics With Subsequent Dementia in Patients With Affective Disorders: A Nationwide Cohort and Nested Case-Control Study.
    The American journal of psychiatry, 2020, 06-01, Volume: 177, Issue:6

    Topics: Aged; Aged, 80 and over; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Azabicycl

2020
Cobalamin deficiency manifested with seizures, mood oscillations, psychotic features and reversible dementia in the absence of typical neurologic and hematologic signs and symptoms: a case report.
    Collegium antropologicum, 2013, Volume: 37, Issue:1

    Topics: Carbamazepine; Dementia; Diazepam; Electroencephalography; Haloperidol; Hematology; Humans; Hydroxoc

2013
A patient with progressive cognitive decline and periodic abnormal waves in EEG: PLEDs of neurosyphilis or PSDs of Creutzfeldt-Jakob disease?
    Clinical EEG and neuroscience, 2014, Volume: 45, Issue:3

    Topics: Atrophy; China; Coma; Creutzfeldt-Jakob Syndrome; Dementia; Diagnosis, Differential; Diazepam; Diffu

2014
EFFECTS OF DIAZEPAM SUSPENSION IN GERIATRIC PATIENTS HOSPITALIZED FOR PSYCHIATRIC ILLNESSES.
    Journal of the American Geriatrics Society, 1965, Volume: 13

    Topics: Aged; Biomedical Research; Dementia; Diazepam; Drug Therapy; Geriatrics; Humans; Mental Disorders; P

1965
Modifications in avoidance reactions of mice, on a second exposure to the hot plate, resist to various amnesia-inducing treatments.
    Brain research. Cognitive brain research, 2005, Volume: 25, Issue:1

    Topics: Analysis of Variance; Animals; Anticonvulsants; Avoidance Learning; Behavior, Animal; Dementia; Diaz

2005
Evaluation of nootropic potential of Ocimum sanctum Linn. in mice.
    Indian journal of experimental biology, 2006, Volume: 44, Issue:2

    Topics: Alzheimer Disease; Amnesia; Animals; Dementia; Diazepam; Dose-Response Relationship, Drug; Humans; M

2006
[The problem of the so-called dialysis encephalopathy].
    Sammlung zwangloser Abhandlungen aus dem Gebiete der Psychiatrie und Neurologie, 1982, Volume: 50

    Topics: Adolescent; Adult; Brain Damage, Chronic; Dementia; Diazepam; Electroencephalography; Evoked Potenti

1982
[The acute psychiatric emergency].
    Zeitschrift fur Alternsforschung, 1981, Volume: 36, Issue:4

    Topics: Acute Disease; Aged; Alcoholism; Amitriptyline; Brain Ischemia; Cognition Disorders; Consciousness D

1981
[Benzodiazepines in geriatrics--a case report on prolonged action].
    Anaesthesiologie und Reanimation, 1996, Volume: 21, Issue:5

    Topics: Aged; Anti-Anxiety Agents; Dementia; Diazepam; Diverticulitis, Colonic; Drug Therapy, Combination; E

1996
[Transurethral resection of the prostate for patients with dementia].
    Hinyokika kiyo. Acta urologica Japonica, 1999, Volume: 45, Issue:4

    Topics: Aged; Aged, 80 and over; Anesthesia, Spinal; Anesthetics, Dissociative; Anesthetics, Intravenous; De

1999
Drug-induced encephalopathy in patients on maintenance haemodialysis.
    Lancet (London, England), 1976, Oct-02, Volume: 2, Issue:7988

    Topics: Aged; Anti-Anxiety Agents; Arthritis; Coronary Disease; Dementia; Diazepam; Flurazepam; Fractures, B

1976
Second thoughts on dementia. Evaluation and management of patients with mild dementia.
    Primary care, 1975, Volume: 2, Issue:1

    Topics: Aged; Amitriptyline; Anxiety; Chlordiazepoxide; Dementia; Depression; Diazepam; Female; Humans; Male

1975
[Problem of transient dementias of old age (clinico-diagnostic aspect)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1985, Volume: 85, Issue:9

    Topics: Aged; Amphetamine; Anxiety; Central Nervous System Stimulants; Dementia; Depressive Disorder; Diagno

1985
[Some suggestions on epileptic psychoses, their differential diagnosis and therapy].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1986, Volume: 38, Issue:2

    Topics: Anticonvulsants; Antipsychotic Agents; Clonazepam; Dementia; Diagnosis, Differential; Diazepam; Drug

1986
Assessment of therapy in psychogeriatric illness.
    Gerontologia clinica, 1974, Volume: 16, Issue:1

    Topics: Affective Symptoms; Aged; Antidepressive Agents; Brain Diseases; Delirium; Dementia; Diagnosis, Diff

1974
[On the syndrome of progessive myoclonus epilepsy according to Lundborg. (A clinical course observation for fifteen years)].
    Schweizer Archiv fur Neurologie, Neurochirurgie und Psychiatrie = Archives suisses de neurologie, neurochirurgie et de psychiatrie, 1968, Volume: 102, Issue:1

    Topics: Adult; Cachexia; Cerebellar Diseases; Dementia; Diazepam; Electroencephalography; Electromyography;

1968
The use of psychopharmacological drugs in the aged.
    Geriatrics, 1971, Volume: 26, Issue:6

    Topics: Affective Symptoms; Aged; Antidepressive Agents; Anxiety; Barbiturates; Butyrophenones; Dementia; De

1971
[Psychopharmacological agents in treatment of psychiatric emergencies].
    La Clinica terapeutica, 1971, Mar-31, Volume: 56, Issue:6

    Topics: Adult; Age Factors; Aged; Antidepressive Agents; Dementia; Diazepam; Haloperidol; Humans; Hypnotics

1971
[Parenteral treatment of depressive diseases].
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1970, Oct-10, Volume: 44, Issue:40

    Topics: Antidepressive Agents; Bipolar Disorder; Dementia; Depression; Depressive Disorder, Major; Desiprami

1970