Page last updated: 2024-10-25

diazepam and Delirium of Mixed Origin

diazepam has been researched along with Delirium of Mixed Origin in 35 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Research Excerpts

ExcerptRelevanceReference
"Neuroinflammation is associated with the development of hypoactive delirium, which results in poor clinical outcomes."5.72Yokukansan suppresses neuroinflammation in the hippocampus of mice and decreases the duration of lipopolysaccharide- and diazepam-mediated loss of righting reflex induced by pentobarbital. ( Ishida, T; Jobu, K; Kawada, K; Kawazoe, T; Miyamura, M; Morisawa, S; Nishida, M; Nishimura, S; Tamura, N; Yoshioka, S, 2022)
"A case is presented in which a 68-year-old man became delirious after being withdrawn from a low dosage of alprazolam."5.27Alprazolam withdrawal delirium unresponsive to diazepam: case report. ( Baker, RW; Zimmer, B; Zipursky, RB, 1985)
"The delirium-free protocol (DFP) group was given an intramuscular injection of diazepam at 20:00 h each night, as well as a continuous intravenous infusion of flunitrazepam and pethidine administered over 8 h, for the first three nights postoperatively."5.10A novel approach to the prevention of postoperative delirium in the elderly after gastrointestinal surgery. ( Aizawa, K; Kanai, T; Kawano, Y; Miyazawa, N; Saikawa, Y; Takabayashi, T; Yamamoto, T, 2002)
"The World Health Organization recommends that anxiety, depression, agitation and delirium at end of life should be treated with drugs such as lorazepam, diazepam, midazolam and haloperidol."3.83Look again at psychedelic drugs. ( Cameron, R, 2016)
"Terminal restlessness is a variant of delirium observed in some patients in their last days of life."2.40Palliative care: an update on "terminal restlessness". ( Burke, AL, 1997)
"Delirium was associated with higher daily GHB consumption prior to admission, while duration of GHB use, time from presentation to first dose of diazepam, and concomitant methamphetamine use were inversely associated with delirium."1.91Inpatient GHB withdrawal management in an inner-city hospital in Sydney, Australia: a retrospective medical record review. ( Brett, J; Ezard, N; Freeman, G; Lindsey, R; Roberts, DM; Rodgers, C; Siefried, KJ, 2023)
"Neuroinflammation is associated with the development of hypoactive delirium, which results in poor clinical outcomes."1.72Yokukansan suppresses neuroinflammation in the hippocampus of mice and decreases the duration of lipopolysaccharide- and diazepam-mediated loss of righting reflex induced by pentobarbital. ( Ishida, T; Jobu, K; Kawada, K; Kawazoe, T; Miyamura, M; Morisawa, S; Nishida, M; Nishimura, S; Tamura, N; Yoshioka, S, 2022)
"Infant delirium is an under-recognized clinical entity in neonatal intensive care, and earlier identification and treatment could minimize morbidities associated with this condition."1.46A case of infant delirium in the neonatal intensive care unit. ( Bidegain, M; Cotten, CM; Edwards, LE; Hornik, CD; Hutchison, LB; Smith, PB, 2017)
"Anticholinergic syndrome has been widely documented in the literature but is uncommon in paediatric medicine."1.34'Red as a beet and blind as a bat' Anticholinergic delirium in adolescents: lessons for the paediatrician. ( Elliott, EJ; Isbister, GK; Ramjan, KA; Williams, AJ, 2007)
"A case is presented in which a 68-year-old man became delirious after being withdrawn from a low dosage of alprazolam."1.27Alprazolam withdrawal delirium unresponsive to diazepam: case report. ( Baker, RW; Zimmer, B; Zipursky, RB, 1985)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199021 (60.00)18.7374
1990's2 (5.71)18.2507
2000's4 (11.43)29.6817
2010's5 (14.29)24.3611
2020's3 (8.57)2.80

Authors

AuthorsStudies
Kawada, K1
Ishida, T1
Jobu, K1
Morisawa, S1
Kawazoe, T1
Nishida, M1
Nishimura, S1
Tamura, N1
Yoshioka, S1
Miyamura, M1
Mäkinen, VN1
Hansen, KB1
Knudsen, ST1
Siefried, KJ2
Freeman, G2
Roberts, DM2
Lindsey, R2
Rodgers, C2
Ezard, N2
Brett, J2
Sopena Bert, E1
Qanneta, R1
Valentí Moreno, V1
San José Laporte, A1
Zhang, P1
Austin, E1
Thompson, M1
Lin, S1
Cameron, R1
Edwards, LE1
Hutchison, LB1
Hornik, CD1
Smith, PB1
Cotten, CM1
Bidegain, M1
Bell, J1
Collins, R1
Grace, RF1
Andersen, KL1
Videbech, P1
Ramjan, KA1
Williams, AJ1
Isbister, GK1
Elliott, EJ1
Werner, V1
Diehl, LW1
Kulik, AV1
Wilbur, R1
Burke, AL1
Matsushima, E1
Nakajima, K1
Moriya, H1
Matsuura, M1
Motomiya, T1
Kojima, T1
Aizawa, K1
Kanai, T1
Saikawa, Y1
Takabayashi, T1
Kawano, Y1
Miyazawa, N1
Yamamoto, T1
Silbermann, RM1
Boer, F1
Zipursky, RB1
Baker, RW1
Zimmer, B1
Gran, L1
Ro, JS1
Borenstein, P1
Champion, C1
Cujo, P1
Gekière, F1
Olivenstein, C1
Kramarz, P1
Zsadányi, O1
Molnár, C1
Coppel, DL1
Bovill, JG4
Dundee, JW6
Gedeon, A1
Várkonyi, S1
Sussman, DR1
Mahomedy, YH1
Downing, JW1
Coleman, AJ1
Mahomedy, MC1
Bergmann, K1
Rawson, RA1
Lipscomb, WR1
Rozynko, J1
Isaac, M2
Pandit, SK3
Galway, JE1
Heiberg, A1
Clarke, RS3
Knox, JW2
Peters, UH1
Seidel, M1
Daniel, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Namenda as Prevention for Post-Operative Delirium[NCT00303433]Phase 430 participants Interventional2006-03-31Terminated
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for diazepam and Delirium of Mixed Origin

ArticleYear
[The state of psychopharmacotherapy in geriatrics 2].
    Therapie der Gegenwart, 1980, Volume: 119, Issue:12

    Topics: Actihaemyl; Aged; Amitriptyline; Bencyclane; Cerebrovascular Circulation; Clorazepate Dipotassium; D

1980
Palliative care: an update on "terminal restlessness".
    The Medical journal of Australia, 1997, Jan-06, Volume: 166, Issue:1

    Topics: Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Clonazepam; Delirium; Diazepam; Humans;

1997

Trials

6 trials available for diazepam and Delirium of Mixed Origin

ArticleYear
The effect of variable-dose diazepam on dreaming and emergence phenomena in 400 cases of ketamine-fentanyl anaesthesia.
    Anaesthesia, 2003, Volume: 58, Issue:9

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia Recovery Period; Anesthetics, Combined; Anesthetics, Dissoc

2003
A psychophysiological study of the development of delirium in coronary care units.
    Biological psychiatry, 1997, Jun-15, Volume: 41, Issue:12

    Topics: Anti-Anxiety Agents; Antipsychotic Agents; Coronary Care Units; Coronary Disease; Delirium; Diazepam

1997
A novel approach to the prevention of postoperative delirium in the elderly after gastrointestinal surgery.
    Surgery today, 2002, Volume: 32, Issue:4

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anti-Anxiety Agents; Delirium; Diazepam; Digestive Syst

2002
[An original psychotropic drug: sulpiride].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1969, Apr-20, Volume: 45, Issue:19

    Topics: Adult; Animals; Anxiety; Behavior; Clinical Trials as Topic; Cognition Disorders; Delirium; Depressi

1969
The taming of ketamine.
    Anaesthesia, 1973, Volume: 28, Issue:3

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Intravenous; Atropine; Delirium; Diazepam; Dreams; Droperi

1973
Ketamine and the obstetric patient.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974, Apr-13, Volume: 48, Issue:17

    Topics: Anesthesia, General; Anesthesia, Intravenous; Anesthesia, Obstetrical; Cesarean Section; Cognition;

1974

Other Studies

27 other studies available for diazepam and Delirium of Mixed Origin

ArticleYear
Yokukansan suppresses neuroinflammation in the hippocampus of mice and decreases the duration of lipopolysaccharide- and diazepam-mediated loss of righting reflex induced by pentobarbital.
    Journal of natural medicines, 2022, Volume: 76, Issue:3

    Topics: Animals; Delirium; Diazepam; Drugs, Chinese Herbal; Glycyrrhizic Acid; Hippocampus; Inflammation; In

2022
[Acute benzodiazepine withdrawal delirium].
    Ugeskrift for laeger, 2022, 06-06, Volume: 184, Issue:23

    Topics: Alcohol Withdrawal Delirium; Benzodiazepines; Delirium; Diazepam; Humans; Male; Middle Aged; Oxazepa

2022
Inpatient GHB withdrawal management in an inner-city hospital in Sydney, Australia: a retrospective medical record review.
    Psychopharmacology, 2023, Volume: 240, Issue:1

    Topics: 4-Butyrolactone; Baclofen; Delirium; Diazepam; Female; Hospitals, Urban; Humans; Inpatients; Male; M

2023
Inpatient GHB withdrawal management in an inner-city hospital in Sydney, Australia: a retrospective medical record review.
    Psychopharmacology, 2023, Volume: 240, Issue:1

    Topics: 4-Butyrolactone; Baclofen; Delirium; Diazepam; Female; Hospitals, Urban; Humans; Inpatients; Male; M

2023
Inpatient GHB withdrawal management in an inner-city hospital in Sydney, Australia: a retrospective medical record review.
    Psychopharmacology, 2023, Volume: 240, Issue:1

    Topics: 4-Butyrolactone; Baclofen; Delirium; Diazepam; Female; Hospitals, Urban; Humans; Inpatients; Male; M

2023
Inpatient GHB withdrawal management in an inner-city hospital in Sydney, Australia: a retrospective medical record review.
    Psychopharmacology, 2023, Volume: 240, Issue:1

    Topics: 4-Butyrolactone; Baclofen; Delirium; Diazepam; Female; Hospitals, Urban; Humans; Inpatients; Male; M

2023
Aproach to the risk of delirium in an orthogeriatric unit.
    Medicina clinica, 2019, 04-18, Volume: 152, Issue:8

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Antipsychotic Agents; Benzodiazepines; Case-Control Stu

2019
Challenges in a large mixed drug overdose patient.
    BMJ case reports, 2016, Jun-22, Volume: 2016

    Topics: Adult; Anticonvulsants; Body Temperature Regulation; Critical Care; Delirium; Diazepam; Drug Overdos

2016
Look again at psychedelic drugs.
    Nursing standard (Royal College of Nursing (Great Britain) : 1987), 2016, Jun-29, Volume: 30, Issue:44

    Topics: Anxiety; Delirium; Depression; Diazepam; Hallucinogens; Haloperidol; Humans; Lorazepam; Midazolam; P

2016
A case of infant delirium in the neonatal intensive care unit.
    Journal of neonatal-perinatal medicine, 2017, Volume: 10, Issue:1

    Topics: Amines; Analgesics, Opioid; Anti-Anxiety Agents; Cardiac Catheterization; Cyclohexanecarboxylic Acid

2017
Gamma-butyrolactone (GBL) dependence and withdrawal.
    Addiction (Abingdon, England), 2011, Volume: 106, Issue:2

    Topics: 4-Butyrolactone; Adult; Ambulatory Care; Baclofen; Delirium; Diazepam; Dose-Response Relationship, D

2011
[Treatment of postictal (emergence) delirium after electroconvulsive therapy].
    Ugeskrift for laeger, 2005, Aug-29, Volume: 167, Issue:35

    Topics: Anti-Anxiety Agents; Delirium; Diazepam; Electroconvulsive Therapy; Female; Humans; Middle Aged

2005
'Red as a beet and blind as a bat' Anticholinergic delirium in adolescents: lessons for the paediatrician.
    Journal of paediatrics and child health, 2007, Volume: 43, Issue:11

    Topics: Acute Disease; Adolescent; Anti-Anxiety Agents; Cholinergic Antagonists; Delirium; Diazepam; Halluci

2007
Delirium and stereotypy from anticholinergic antiparkinson drugs.
    Progress in neuro-psychopharmacology & biological psychiatry, 1982, Volume: 6, Issue:1

    Topics: Adult; Aged; Benztropine; Delirium; Diazepam; Drug Therapy, Combination; Dyskinesia, Drug-Induced; E

1982
[A life-threatening psychosis].
    Nederlands tijdschrift voor geneeskunde, 1975, May-03, Volume: 119, Issue:18

    Topics: Acute Disease; Delirium; Dexamethasone; Diazepam; Drug Interactions; Drug-Related Side Effects and A

1975
Alprazolam withdrawal delirium unresponsive to diazepam: case report.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:8

    Topics: Aged; Alprazolam; Anti-Anxiety Agents; Benzodiazepines; Delirium; Diazepam; Half-Life; Humans; Male;

1985
[Delirium in a diazepam-treated tetanus patient].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1969, Apr-15, Volume: 89, Issue:8

    Topics: Aged; Delirium; Diazepam; gamma-Globulins; Humans; Male; Tetanus; Time Factors

1969
Electroencephalographic analysis of atropine coma.
    Acta physiologica Academiae Scientiarum Hungaricae, 1972, Volume: 41, Issue:1

    Topics: Atropine; Barbiturates; Bipolar Disorder; Coma; Delirium; Diazepam; Electroencephalography; Epilepsy

1972
Symptomatic treatment of myocardial infarction and acute psychosyndrome with Seduxen injections.
    Therapia Hungarica (English edition), 1973, Volume: 21, Issue:1

    Topics: Acute Disease; Delirium; Diazepam; Female; Humans; Injections, Intramuscular; Injections, Intravenou

1973
A comparative evaluation of ketamine anesthesia in children and adults.
    Anesthesiology, 1974, Volume: 40, Issue:5

    Topics: Adolescent; Adult; Age Factors; Airway Obstruction; Analgesia; Anesthesia, General; Anesthesia, Intr

1974
Assessment of therapy in psychogeriatric illness.
    Gerontologia clinica, 1974, Volume: 16, Issue:1

    Topics: Affective Symptoms; Aged; Antidepressive Agents; Brain Diseases; Delirium; Dementia; Diagnosis, Diff

1974
Acute delirium in amitriptyline-perphenazine therapy of alcoholism.
    Clinical toxicology, 1971, Volume: 4, Issue:1

    Topics: Acute Disease; Adult; Alcoholism; Amitriptyline; Delirium; Diazepam; Drug Combinations; Hallucinatio

1971
Intravenous ethanol anaesthesia. A study of sequelae and their implications.
    Acta anaesthesiologica Scandinavica, 1971, Volume: 15, Issue:3

    Topics: Alcohol Deterrents; Alcoholic Intoxication; Amnesia; Anesthesia, Intravenous; Atropine; Barbiturates

1971
[Delirious reactions in acute pancreatitis].
    Nordisk medicin, 1969, Sep-11, Volume: 82, Issue:37

    Topics: Acute Disease; Adult; Cerebral Ventriculography; Chlorprothixene; Cholecystectomy; Delirium; Diazepa

1969
Clinical studies of induction agents. 35. Studies on combination of ethanol with methohexitone and diazepam.
    British journal of anaesthesia, 1970, Volume: 42, Issue:6

    Topics: Anesthesia, Intravenous; Atropine; Delirium; Diazepam; Ethanol; Humans; Methohexital; Preanesthetic

1970
The effect of dosage and premedication on the action of ketamine.
    British journal of anaesthesia, 1970, Volume: 42, Issue:9

    Topics: Analgesics; Anesthesia, General; Anesthetics; Atropine; Blood Pressure; Cyclohexanes; Delirium; Diaz

1970
Clinical studies of induction agents. XXXVI: Ketamine.
    British journal of anaesthesia, 1970, Volume: 42, Issue:10

    Topics: Adult; Analgesics; Anesthesia, Intravenous; Anesthetics; Atropine; Attitude to Health; Blood Pressur

1970
[Drug abuse and addiction to diazepam].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:7

    Topics: Anxiety; Delirium; Depression; Diazepam; Humans; Substance Withdrawal Syndrome; Substance-Related Di

1970
Problems with ketamine in adults.
    Anaesthesia, 1971, Volume: 26, Issue:1

    Topics: Adult; Anesthetics; Benperidol; Cyclohexanes; Delirium; Diazepam; Humans; Hypertension; Injections,

1971
[New treatment methods of symptoms of delirium with a tranquilizing agent].
    Therapie der Gegenwart, 1966, Volume: 105, Issue:10

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Delirium; Diazepam; Humans; Infant; Infant, Newbor

1966