diazepam has been researched along with De Lange Syndrome in 2 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
De Lange Syndrome: A syndrome characterized by growth retardation, severe MENTAL RETARDATION, short stature, a low-pitched growling cry, brachycephaly, low-set ears, webbed neck, carp mouth, depressed nasal bridge, bushy eyebrows meeting at the midline, hirsutism, and malformations of the hands. The condition may occur sporadically or be associated with an autosomal dominant pattern of inheritance or duplication of the long arm of chromosome 3. (Menkes, Textbook of Child Neurology, 5th ed, p231)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlorpromazine and fluphenazine decanoate were employed to treat aggressive behavior and emesis in a 22-year-old patient with Cornelia de Lange syndrome." | 3.66 | Pharmacological treatment of aggressive behavior and emesis in the Cornelia de Lange Syndrome. ( Andrasik, F; Hughes, JR; Ollendick, TH; Turner, SM, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrasik, F | 1 |
| Ollendick, TH | 1 |
| Turner, SM | 1 |
| Hughes, JR | 1 |
| Calderon-Gonzalez, R | 1 |
| Hopkins, I | 1 |
| McLean, WT | 1 |
2 other studies available for diazepam and De Lange Syndrome
| Article | Year |
|---|---|
Pharmacological treatment of aggressive behavior and emesis in the Cornelia de Lange Syndrome.
Topics: Adult; Aggression; Chlorpromazine; De Lange Syndrome; Diazepam; Drug Therapy, Combination; Fluphenaz | 1979 |
Tap seizures. A form of sensory precipitation epilepsy.
Topics: Birth Injuries; Child, Preschool; De Lange Syndrome; Diazepam; Electroencephalography; Electromyogra | 1966 |