diazepam has been researched along with Cocaine Abuse in 11 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Anxiety was assessed on the elevated plus maze (EPM) both prior to and following the administration of the anxiolytic drug diazepam, and by blood corticosterone levels following forced novelty exposure." | 3.77 | High impulsivity predicting vulnerability to cocaine addiction in rats: some relationship with novelty preference but not novelty reactivity, anxiety or stress. ( Belin, D; Caprioli, D; Dalley, JW; Everitt, BJ; Mar, A; Molander, AC; Moreno, M; Norbury, A; Robbins, TW; Steventon, S; Theobald, DE, 2011) |
| "These results suggest that, among alcohol abusers, cocaine is a complement to alcohol, but alcohol is a substitute for cocaine." | 1.31 | A behavioral economic analysis of polydrug abuse in alcoholics: asymmetrical substitution of alcohol and cocaine. ( Petry, NM, 2001) |
| "Diazepam has an important role in the management of cardiac complications after cocaine use and should be used early in management." | 1.30 | Cocaine induced myocardial infarction. ( Cooper, AJ; Hodgkinson, DW; Inyang, VA, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Pantazis, CB | 1 |
| Aston-Jones, G | 1 |
| Peake, ST | 1 |
| Das, S | 1 |
| Greene, S | 1 |
| Dubrey, SW | 1 |
| Lu, H | 1 |
| Cheng, PL | 1 |
| Lim, BK | 1 |
| Khoshnevisrad, N | 1 |
| Poo, MM | 1 |
| Molander, AC | 1 |
| Mar, A | 1 |
| Norbury, A | 1 |
| Steventon, S | 1 |
| Moreno, M | 1 |
| Caprioli, D | 1 |
| Theobald, DE | 1 |
| Belin, D | 1 |
| Everitt, BJ | 1 |
| Robbins, TW | 1 |
| Dalley, JW | 1 |
| Augier, E | 1 |
| Vouillac, C | 1 |
| Ahmed, SH | 1 |
| Man, LH | 1 |
| Best, D | 1 |
| Gossop, M | 1 |
| Stillwell, G | 1 |
| Strang, J | 1 |
| Cleveland, NR | 1 |
| Krier, S | 1 |
| Heard, K | 1 |
| Wu, S | 1 |
| Pearl-Davis, MS | 1 |
| Manini, AF | 1 |
| Hoffman, RS | 1 |
| Inyang, VA | 1 |
| Cooper, AJ | 1 |
| Hodgkinson, DW | 1 |
| Baumann, BM | 1 |
| Perrone, J | 1 |
| Hornig, SE | 1 |
| Shofer, FS | 1 |
| Hollander, JE | 1 |
| Petry, NM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Efficacy of Strategic Memory Training Coupled With Non-invasive Brain Stimulation Techniques in Healthy Aging Population and Subjective Cognitive Decline Patients: a Randomized-controlled Study[NCT05929872] | 56 participants (Anticipated) | Interventional | 2023-07-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for diazepam and Cocaine Abuse
| Article | Year |
|---|---|
Randomized, double-blind, placebo-controlled trial of diazepam, nitroglycerin, or both for treatment of patients with potential cocaine-associated acute coronary syndromes.
Topics: Adult; Anticonvulsants; Cocaine-Related Disorders; Coronary Disease; Diazepam; Double-Blind Method; | 2000 |
10 other studies available for diazepam and Cocaine Abuse
| Article | Year |
|---|---|
Lateral septum inhibition reduces motivation for cocaine: Reversal by diazepam.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Diazepam; Disease Models, Animal; Dop | 2020 |
Cocaine 'body packers' and the clinical management of packet rupture.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Condoms; Crime; Diazepam; Drug Packaging; Foreign Bodies; | 2009 |
Elevated BDNF after cocaine withdrawal facilitates LTP in medial prefrontal cortex by suppressing GABA inhibition.
Topics: Animals; Animals, Newborn; Biophysics; Brain-Derived Neurotrophic Factor; Carbazoles; Cocaine; Cocai | 2010 |
High impulsivity predicting vulnerability to cocaine addiction in rats: some relationship with novelty preference but not novelty reactivity, anxiety or stress.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Cocaine-Related Disorders; Conditioning, Operant; Corticoster | 2011 |
Diazepam promotes choice of abstinence in cocaine self-administering rats.
Topics: Administration, Cutaneous; Animals; Anti-Anxiety Agents; Behavior, Animal; Choice Behavior; Cocaine; | 2012 |
Relationship between prescribing and risk of opiate overdose among drug users in and out of maintenance treatment.
Topics: Adult; Alcoholic Intoxication; Benzodiazepines; Causality; Cocaine-Related Disorders; Comorbidity; C | 2004 |
Ziprasidone, diazepam, or the combination for prevention of cocaine toxicity in a mouse model.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Confidence Intervals; Diazepam; Disease Models, Animal; | 2007 |
Use of antipsychotics to treat cocaine toxicity?
Topics: Animals; Antipsychotic Agents; Cocaine; Cocaine-Related Disorders; Diazepam; Disease Models, Animal; | 2008 |
Cocaine induced myocardial infarction.
Topics: Adult; Cocaine-Related Disorders; Diazepam; Electrocardiography; Emergency Treatment; Fibrinolytic A | 1999 |
A behavioral economic analysis of polydrug abuse in alcoholics: asymmetrical substitution of alcohol and cocaine.
Topics: Adult; Alcoholic Beverages; Alcoholism; Analysis of Variance; Cocaine; Cocaine-Related Disorders; Di | 2001 |