diazepam has been researched along with Clasp-Knife Spasticity in 96 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A double-blind study was carried out in 105 patients with chronic spasticity associated with hemiplegia in order to compare the efficacy and tolerability of tizanidine with that of diazepam." | 9.06 | A multi-centre, double-blind trial of tizanidine, a new antispastic agent, in spasticity associated with hemiplegia. ( Bes, A; Eyssette, M; Pierrot-Deseilligny, E; Rohmer, F; Warter, JM, 1988) |
| "This double-blind cross-over study of 14 severely spastic inpatients with chronic multiple sclerosis reveals that once-daily doses of ketazolam, a new drug, are effective in reducing spasticity in a significant proportion of patients without significant side-effects." | 5.06 | Ketazolam once daily for spasticity: double-blind cross-over study. ( Basmajian, JV; Russell, D; Shankardass, K, 1986) |
| "A double-blind study was carried out in 105 patients with chronic spasticity associated with hemiplegia in order to compare the efficacy and tolerability of tizanidine with that of diazepam." | 5.06 | A multi-centre, double-blind trial of tizanidine, a new antispastic agent, in spasticity associated with hemiplegia. ( Bes, A; Eyssette, M; Pierrot-Deseilligny, E; Rohmer, F; Warter, JM, 1988) |
| "The effects of dantrolene sodium and diazepam were compared in a double crossover study of 42 patients with spasticity due to stable multiple sclerosis." | 5.04 | Comparison of dantrolene sodium and diazepam in the treatment of spasticity. ( Lee, RH; Schmidt, RT; Spehlmann, R, 1976) |
| " Analysis of 13 patients with stiff-man syndrome examined at the Mayo Clinic during the past 30 years revealed that treatment with diazepam decreased the muscle spasms." | 4.77 | Stiff-man syndrome updated. ( Howard, FM; Lorish, TR; Thorsteinsson, G, 1989) |
| "Intrathecal baclofen (ITB) is a proven, effective treatment for refractory spasticity and chronic pain, with applications ranging from spinal cord injury to amyotrophic lateralsclerosis (ALS)." | 4.31 | Management of high-dose intrathecal baclofen pump explant: A case report. ( Agrawal, M; Belisle Haley, C; Dayal, R; Newton, K; Yeung, B, 2023) |
| "Selected examples from three series of isomeric (alkylthio)-1,2,4-triazoles were prepared and examined for anticonvulsant activity versus strychnine-, maximal-electroshock-, pentylenetetrazole-, and 3-mercaptopropionic-acid-induced seizures in mice." | 3.69 | 5-Aryl-3-(alkylthio)-4H-1,2,4-triazoles as selective antagonists of strychnine-induced convulsions and potential antispastic agents. ( Dalton, CR; Dudley, MW; Kane, JM; Kehne, JH; Ketteler, HJ; McCloskey, TC; Miller, FP; Ogden, AM; Senyah, Y; Staeger, MA, 1994) |
| " For management of postoperative muscle spasm, an intravenous benzodiazepine was used (diazepam 0." | 3.69 | Pain management for children following selective dorsal rhizotomy. ( Geiduschek, JM; Haberkern, CM; Hays, RM; Jacobson, LE; McLaughlin, JF; Roberts, TS, 1994) |
| "The effects of diazepam on reflex pathways in patients having complete spinal lesions and in patients having incomplete lesions of the spinal cord or multiple sclerosis are compared to determine whether diazepam has an action at spinal level." | 3.65 | Diazepam effect on reflex activity in patients with complete spinal lesions and in those with other causes of spasticity. ( Ashby, P; MacLeod, S; Verrier, M, 1977) |
| "The results indicate that the spasticity of cerebral palsy can be relieved significantly, and that the combination of peripherally and centrally acting agents is more beneficial than either medication alone." | 2.64 | Medical treatment for spasticity in children with cerebral palsy. ( Nogen, AG, 1976) |
| "The intensity of spasticity was measured electromyographically by the amplitude of the stretch reflex at various velocities, and the results were correlated with those obtained by clinical assessment." | 2.63 | A new agent for the control of spasticity. ( Burke, D; Gillies, JD; Jones, RF; Marosszeky, JE, 1970) |
| "No significant difference was found in spasticity scale." | 2.58 | A mixed treatment comparison on efficacy and safety of treatments for spasticity caused by multiple sclerosis: a systematic review and network meta-analysis. ( Fu, X; Li, J; Li, M; Ma, Q; Wang, C; Wang, Y; Wu, H; Yang, W, 2018) |
| "The available studies on spasticity treatment offer some insight to guide clinical practice but are of variable methodological quality." | 2.53 | Pharmacological management of spasticity in multiple sclerosis: Systematic review and consensus paper. ( Comi, G; Gold, R; Hartung, HP; Montalban, X; Otero-Romero, S; Sastre-Garriga, J; Soelberg Sørensen, P; Thompson, AJ; Vermersch, P, 2016) |
| "For localized/segmental spasticity that warrants treatment, botulinum toxin type A should be offered as an effective and generally safe treatment (Level A)." | 2.46 | Practice parameter: pharmacologic treatment of spasticity in children and adolescents with cerebral palsy (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child ( Aisen, M; Ashwal, S; Delgado, MR; Fehlings, DL; Hirtz, D; McLaughlin, J; Morrison, LA; Shrader, MW; Tilton, A; Vargus-Adams, J, 2010) |
| "Gabapentin is a novelty, and the working mechanism of cannabis has been elucidated." | 2.46 | Spasticity: revisiting the role and the individual value of several pharmacological treatments. ( Kuks, JB; Lapeyre, E; Meijler, WJ, 2010) |
| "For more generalized spasticity, a number of useful oral agents and intrathecal baclofen are available, each with their positive and negative attributes." | 2.46 | Pharmacologic treatment of spasticity in children. ( Delgado, MR; Tilton, A; Vargus-Adams, J, 2010) |
| "While in some children, spasticity may adversely impact the motor abilities, in others, it may help maintain posture and ability to ambulate." | 2.43 | Pharmacologic interventions for reducing spasticity in cerebral palsy. ( Patel, DR; Soyode, O, 2005) |
| "Therapy for spasticity is symptomatic with the aim of increasing functional capacity and relieving discomfort." | 2.41 | Drugs used to treat spasticity. ( Goodkin, DE; Kita, M, 2000) |
| "The therapeutic profile of a new antispastic drug cannot be defined solely on the basis of placebo-controlled studies." | 2.39 | Comparative profile of tizanidine in the management of spasticity. ( Davis, C; Emre, M; Groves, L; Lataste, X, 1994) |
| "The functional impairment due to spasticity must be carefully assessed before any treatment is considered." | 2.37 | Management of spasticity. ( Katz, RT, 1988) |
| "In addition, appropriate treatment for spastic torticollis applied after surgery resulted in a favorable outcome of this case." | 1.56 | Surgical treatment for atlantoaxial rotatory fixation in an adult with spastic torticollis: A case report. ( Akatsu, Y; Akazawa, T; Akiyama, Y; Aoki, Y; Eguchi, Y; Furuya, T; Inage, K; Koda, M; Maki, S; Nakagawa, K; Nakajima, A; Ohtori, S; Orita, S; Saito, J; Shiga, Y; Sonobe, M; Takahashi, H; Yamada, M; Yamazaki, M; Yanagisawa, K, 2020) |
| "Isolated dystonia or spasticity was infrequently seen, with a mixed picture of dystonia and spasticity ± choreoathetosis identified in 194/275 (70." | 1.51 | Pharmacological management of abnormal tone and movement in cerebral palsy. ( Amin, S; Basu, A; Cadwgan, J; Crowe, B; DeAlwis, Y; Devlin, A; Kumar, R; Lodh, R; Lumsden, DE; Lundy, CT; Mordekar, SR; Smith, M, 2019) |
| "Baclofen is recommended for spasticity treatment, but it has recently been used for alcohol withdrawal symptoms reduction and alcohol abstinence." | 1.48 | Delirium tremens in an AUD patient after an intrathecal baclofen pump induced total alcohol abstinence. ( Calvo, ME; Gunnarsson, T; Hao, M; Smith, L, 2018) |
| "On examination he was noted to have trismus, generalised muscle spasms, diaphoresis and emotional lability and he was diagnosed with generalised tetanus." | 1.36 | Generalised tetanus in an unvaccinated adult. ( Cavanagh, S; Fleming, C; Muldoon, EG, 2010) |
| "Abecarnil is a beta-carboline agonist at benzodiazepine receptors with potent anxiolytic activity but no muscle relaxant side effects in rodents." | 1.29 | Effect of the beta-carboline abecarnil on spinal reflexes in mice and on muscle tone in genetically spastic rats: a comparison with diazepam. ( Stephens, DN; Turski, L, 1993) |
| "Case series evaluating spasticity using clinical scales commonly referenced in contemporary literature, including the Penn Spasm Frequency Scale, the Ashworth Scale, and standard scales of tendon taps, clonus, and plantar stimulation." | 1.29 | Clinical assessment of spasticity in spinal cord injury: a multidimensional problem. ( Kharas, NF; Markowski, J; Priebe, MM; Sherwood, AM; Thornby, JI, 1996) |
| "Two patients who had severe spinal spasticity with painful flexor spasms were treated with oral baclofen with relief of symptoms." | 1.28 | Pathophysiology and treatment of spasticity: report of two cases. ( Narayanaswamy, AS, 1992) |
| "Dogs, surgically implanted with a chronic gastric fistula, were chronically dosed with N-desmethyldiazepam (32 mg/kg/day) in four divided doses to attain N-desmethyldiazepam plasma levels comparable to those observed in dogs dependent on diazepam (60 mg/kg/day)." | 1.27 | N-desmethyldiazepam physical dependence in dogs. ( Martin, WR; McNicholas, LF; Pruitt, TA, 1985) |
| "Fifty-one spastic patients, divided into four groups, were tested." | 1.27 | Electrophysiological analysis of the mode of action of muscle relaxants in spasticity. ( Delwaide, PJ, 1985) |
| "The muscle relaxant (antispastic) effect of diazepam, alone or in combination with phenytoin, was studied in mutant Han-Wistar rats with progressive spastic paresis." | 1.26 | Interaction between phenytoin and diazepam in mutant Han-Wistar rats with progressive spastic paresis. ( Schwarz, M; Sontag, KH; Turski, L, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 65 (67.71) | 18.7374 |
| 1990's | 12 (12.50) | 18.2507 |
| 2000's | 8 (8.33) | 29.6817 |
| 2010's | 9 (9.38) | 24.3611 |
| 2020's | 2 (2.08) | 2.80 |
| Authors | Studies |
|---|---|
| Kane, JM | 1 |
| Staeger, MA | 1 |
| Dalton, CR | 1 |
| Miller, FP | 1 |
| Dudley, MW | 1 |
| Ogden, AM | 1 |
| Kehne, JH | 1 |
| Ketteler, HJ | 1 |
| McCloskey, TC | 1 |
| Senyah, Y | 1 |
| Belisle Haley, C | 1 |
| Agrawal, M | 1 |
| Newton, K | 1 |
| Yeung, B | 1 |
| Dayal, R | 1 |
| Akiyama, Y | 1 |
| Takahashi, H | 1 |
| Saito, J | 1 |
| Aoki, Y | 1 |
| Nakajima, A | 1 |
| Sonobe, M | 1 |
| Akatsu, Y | 1 |
| Yamada, M | 1 |
| Yanagisawa, K | 1 |
| Shiga, Y | 1 |
| Inage, K | 1 |
| Orita, S | 1 |
| Eguchi, Y | 1 |
| Maki, S | 1 |
| Furuya, T | 1 |
| Akazawa, T | 1 |
| Koda, M | 1 |
| Yamazaki, M | 1 |
| Ohtori, S | 1 |
| Nakagawa, K | 1 |
| Fu, X | 1 |
| Wang, Y | 1 |
| Wang, C | 1 |
| Wu, H | 1 |
| Li, J | 1 |
| Li, M | 1 |
| Ma, Q | 1 |
| Yang, W | 1 |
| Calvo, ME | 1 |
| Gunnarsson, T | 1 |
| Smith, L | 1 |
| Hao, M | 1 |
| Lumsden, DE | 1 |
| Crowe, B | 1 |
| Basu, A | 1 |
| Amin, S | 1 |
| Devlin, A | 1 |
| DeAlwis, Y | 1 |
| Kumar, R | 1 |
| Lodh, R | 1 |
| Lundy, CT | 1 |
| Mordekar, SR | 1 |
| Smith, M | 1 |
| Cadwgan, J | 1 |
| Otero-Romero, S | 1 |
| Sastre-Garriga, J | 1 |
| Comi, G | 1 |
| Hartung, HP | 1 |
| Soelberg Sørensen, P | 1 |
| Thompson, AJ | 1 |
| Vermersch, P | 1 |
| Gold, R | 1 |
| Montalban, X | 1 |
| Lindsay, C | 1 |
| Kouzouna, A | 1 |
| Simcox, C | 1 |
| Pandyan, AD | 1 |
| Muldoon, EG | 1 |
| Cavanagh, S | 1 |
| Fleming, C | 1 |
| Delgado, MR | 2 |
| Hirtz, D | 1 |
| Aisen, M | 1 |
| Ashwal, S | 1 |
| Fehlings, DL | 1 |
| McLaughlin, J | 1 |
| Morrison, LA | 1 |
| Shrader, MW | 1 |
| Tilton, A | 2 |
| Vargus-Adams, J | 2 |
| Benecke, R | 1 |
| Patejdl, R | 1 |
| Lapeyre, E | 1 |
| Kuks, JB | 1 |
| Meijler, WJ | 1 |
| RETT, A | 1 |
| GLOGOWSKI, G | 1 |
| HUMEKENDALL, P | 1 |
| FOWLKS, EW | 1 |
| STRICKLAND, DA | 1 |
| PEIRSON, GA | 1 |
| CIBEIRA, JB | 1 |
| BUZZI, A | 1 |
| DOMINELLI, JC | 1 |
| SCHLAEPFER, U | 1 |
| MUMENTHALER, M | 1 |
| Tilton, AH | 1 |
| Mathew, A | 1 |
| Mathew, MC | 1 |
| Thomas, M | 1 |
| Antonisamy, B | 1 |
| Patel, DR | 1 |
| Soyode, O | 1 |
| Hattan, E | 1 |
| Angle, MR | 1 |
| Chalk, C | 1 |
| Vernino, S | 1 |
| McEvoy, K | 1 |
| Basmajian, JV | 2 |
| Schwarz, M | 3 |
| Turski, L | 4 |
| Sontag, KH | 3 |
| Pedersen, E | 1 |
| Young, RR | 3 |
| Delwaide, PJ | 5 |
| Hennies, OL | 1 |
| Karepov, VG | 1 |
| Turski, WA | 1 |
| Ikonomidou, C | 1 |
| McLellan, DL | 1 |
| Goold, JE | 1 |
| Kobernick, M | 1 |
| Mårtensson, A | 1 |
| Lossius, R | 2 |
| Dietrichson, P | 1 |
| Lunde, PK | 1 |
| Delaney, JF | 1 |
| Knutsson, E | 1 |
| Dimitrijevic, MR | 1 |
| Sherwood, AM | 2 |
| DeLisa, JA | 1 |
| Little, J | 1 |
| Melnick, ME | 1 |
| Shellenberger, MK | 1 |
| Tibbs, PA | 1 |
| Young, AB | 1 |
| Walsh, JW | 1 |
| Bean, JR | 1 |
| Burton, L | 1 |
| Kaplan, WE | 1 |
| Firlit, CF | 1 |
| Schoenberg, HW | 1 |
| Nathan, PW | 2 |
| Frisbie, JH | 1 |
| Aguilera, EJ | 1 |
| Kuhn, WF | 1 |
| Light, PJ | 1 |
| Kuhn, SC | 1 |
| Lataste, X | 1 |
| Emre, M | 1 |
| Davis, C | 1 |
| Groves, L | 1 |
| Geiduschek, JM | 1 |
| Haberkern, CM | 1 |
| McLaughlin, JF | 1 |
| Jacobson, LE | 1 |
| Hays, RM | 1 |
| Roberts, TS | 1 |
| Barnes, MP | 1 |
| Stephens, DN | 1 |
| Kaufman, DK | 1 |
| Brown, RD | 1 |
| Karnes, WE | 1 |
| Priebe, MM | 1 |
| Thornby, JI | 1 |
| Kharas, NF | 1 |
| Markowski, J | 1 |
| Broderick, CP | 1 |
| Radnitz, CL | 1 |
| Bauman, WA | 1 |
| Kita, M | 1 |
| Goodkin, DE | 1 |
| Francisco, GE | 1 |
| Kothari, S | 1 |
| Huls, C | 1 |
| Brown, BR | 1 |
| Womble, J | 1 |
| Hubbert, CH | 1 |
| Hannigan, J | 1 |
| Schmidt, RT | 1 |
| Lee, RH | 1 |
| Spehlmann, R | 1 |
| Nogen, AG | 1 |
| Verrier, M | 1 |
| Ashby, P | 1 |
| MacLeod, S | 1 |
| Gautier-Smith, PC | 1 |
| Narayanaswamy, AS | 1 |
| Dietz, V | 1 |
| Lorish, TR | 1 |
| Thorsteinsson, G | 1 |
| Howard, FM | 1 |
| Shankardass, K | 1 |
| Russell, D | 1 |
| Watanabe, K | 1 |
| Azouvi, P | 1 |
| Roby-Brami, A | 1 |
| Tougeron, A | 1 |
| Bussel, B | 1 |
| Bes, A | 1 |
| Eyssette, M | 1 |
| Pierrot-Deseilligny, E | 1 |
| Rohmer, F | 1 |
| Warter, JM | 1 |
| Katz, RT | 1 |
| Roussan, M | 1 |
| Terrence, C | 1 |
| Fromm, G | 1 |
| McNicholas, LF | 1 |
| Martin, WR | 1 |
| Pruitt, TA | 1 |
| Ducamp, E | 1 |
| Albin, H | 1 |
| Barat, M | 1 |
| Larsen, TA | 1 |
| Teräväinen, H | 1 |
| Macdonald, AG | 1 |
| Carmichael, AF | 1 |
| Hartmann-von Monakow, K | 1 |
| Reichel, G | 1 |
| Stahl, J | 1 |
| Herman, R | 1 |
| Freedman, W | 1 |
| Mayer, N | 1 |
| Glass, A | 1 |
| Hannah, A | 1 |
| Iyer, GV | 1 |
| Abraham, J | 1 |
| Taori, GM | 1 |
| Cartlidge, NE | 1 |
| Hudgson, P | 1 |
| Weightman, D | 1 |
| Jones, RF | 1 |
| Burke, D | 1 |
| Marosszeky, JE | 1 |
| Gillies, JD | 1 |
| Cocchiarella, A | 1 |
| Downey, JA | 1 |
| Darling, RC | 1 |
| Corbett, M | 1 |
| Frankel, HL | 1 |
| Michaelis, L | 1 |
| Henning, K | 1 |
| Edelmann, P | 1 |
| Giménez Roldán, S | 1 |
| Martínez Fuertes, L | 1 |
| Avila, J | 1 |
| Lenman, JA | 1 |
| Paeslack, V | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of EXOPULSE Mollii Suit on Spasticity and Muscular Oxygenation in Patients With Multiple Sclerosis.[NCT05912595] | 36 participants (Anticipated) | Interventional | 2023-05-18 | Recruiting | |||
| Effects of Neuromuscular Electrical Stimulation on Walking Ability and Quality of Life in Individuals With Chronic Stroke[NCT04673045] | 40 participants (Anticipated) | Interventional | 2021-02-02 | Recruiting | |||
| Radial Extracorporeal Shock Wave Therapy for Management of Spasticity in Patients With Cerebral Palsy[NCT05702606] | 73 participants (Actual) | Interventional | 2021-06-10 | Completed | |||
| Sensory-Motor Rehabilitation Post Stroke[NCT02369770] | 140 participants (Anticipated) | Interventional | 2019-04-26 | Recruiting | |||
| The Use of Penile Vibratory Stimulation to Decrease Spasticity Following Spinal Cord Injury[NCT00223873] | 30 participants | Interventional | 2002-11-30 | Completed | |||
| A Phase III, Multicenter, Randomized Study to Assess the Efficacy and Safety of 0,5 mg Tizaspray® Administered Intranasally Versus Sirdalud® 2 mg Tablets, in Patients With Acute Low Back Pain[NCT02934061] | Phase 3 | 117 participants (Actual) | Interventional | 2016-10-31 | Completed | ||
| Botulinum Toxin Urethral Sphincter Injection for Dysfunctional Voiding - A Multicenter Study, Randomized, Double-Blind, Placebo Control[NCT01733290] | Phase 2 | 70 participants (Actual) | Interventional | 2012-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
20 reviews available for diazepam and Clasp-Knife Spasticity
| Article | Year |
|---|---|
A mixed treatment comparison on efficacy and safety of treatments for spasticity caused by multiple sclerosis: a systematic review and network meta-analysis.
Topics: Baclofen; Botulinum Toxins, Type A; Cannabinoids; Clonidine; Diazepam; Humans; Multiple Sclerosis; M | 2018 |
Pharmacological management of spasticity in multiple sclerosis: Systematic review and consensus paper.
Topics: Amines; Analgesics; Baclofen; Cannabidiol; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Diaze | 2016 |
Pharmacological interventions other than botulinum toxin for spasticity after stroke.
Topics: Baclofen; Botulinum Toxins, Type A; Clonidine; Diazepam; Humans; Muscle Relaxants, Central; Muscle S | 2016 |
Practice parameter: pharmacologic treatment of spasticity in children and adolescents with cerebral palsy (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child
Topics: Adolescent; Botulinum Toxins, Type A; Cerebral Palsy; Child; Clonidine; Diazepam; Humans; Muscle Rel | 2010 |
Practice parameter: pharmacologic treatment of spasticity in children and adolescents with cerebral palsy (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child
Topics: Adolescent; Botulinum Toxins, Type A; Cerebral Palsy; Child; Clonidine; Diazepam; Humans; Muscle Rel | 2010 |
Practice parameter: pharmacologic treatment of spasticity in children and adolescents with cerebral palsy (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child
Topics: Adolescent; Botulinum Toxins, Type A; Cerebral Palsy; Child; Clonidine; Diazepam; Humans; Muscle Rel | 2010 |
Practice parameter: pharmacologic treatment of spasticity in children and adolescents with cerebral palsy (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child
Topics: Adolescent; Botulinum Toxins, Type A; Cerebral Palsy; Child; Clonidine; Diazepam; Humans; Muscle Rel | 2010 |
[New therapies for spastic movement disorders].
Topics: Administration, Oral; Baclofen; Botulinum Toxins, Type A; Cannabinoids; Clonidine; Diazepam; Humans; | 2009 |
Spasticity: revisiting the role and the individual value of several pharmacological treatments.
Topics: Amines; Baclofen; Botulinum Toxins; Calcium Channel Blockers; Clonidine; Cyclohexanecarboxylic Acids | 2010 |
Pharmacologic treatment of spasticity in children.
Topics: Age Factors; Baclofen; Botulinum Toxins; Child; Clonidine; Dantrolene; Diazepam; Humans; Injections, | 2010 |
Approach to the rehabilitation of spasticity and neuromuscular disorders in children.
Topics: Anticonvulsants; Botulinum Toxins; Child; Diazepam; Humans; Muscle Relaxants, Central; Muscle Spasti | 2003 |
Pharmacologic interventions for reducing spasticity in cerebral palsy.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Age Factors; Anti-Infective Agents, Local; Baclofen | 2005 |
Antispastic medication. A review.
Topics: Baclofen; Dantrolene; Diazepam; Electromyography; Humans; Muscle Spasticity | 1981 |
Spasticity: medical and surgical treatment.
Topics: Ambulatory Care; Ataxia; Baclofen; Dantrolene; Diazepam; Electric Stimulation; Electrodes; Electroen | 1980 |
Drug therapy: spasticity (second of two parts).
Topics: Baclofen; Diazepam; Humans; Muscle Spasticity; Parasympatholytics | 1981 |
Comparative profile of tizanidine in the management of spasticity.
Topics: Activities of Daily Living; Baclofen; Clonidine; Diazepam; Humans; Muscle Relaxants, Central; Muscle | 1994 |
Local treatment of spasticity.
Topics: Baclofen; Dantrolene; Diazepam; Humans; Muscle Spasticity; Nerve Block; Phenol; Phenols; Physical Th | 1993 |
Drugs used to treat spasticity.
Topics: Baclofen; Clonidine; Dantrolene; Diazepam; Drug Administration Schedule; Humans; Muscle Relaxants, C | 2000 |
GABA agonists and gabapentin for spastic hypertonia.
Topics: Acetates; Amines; Animals; Anticonvulsants; Baclofen; Benzodiazepines; Cyclohexanecarboxylic Acids; | 2001 |
[Spasticity: therapy of increased reflexes or movement disorder?].
Topics: Baclofen; Clonidine; Combined Modality Therapy; Dantrolene; Diazepam; Glycine; Humans; Locomotion; M | 1990 |
Stiff-man syndrome updated.
Topics: Adult; Diagnosis, Differential; Diazepam; Electromyography; Female; Gait; Humans; Lordosis; Male; Mi | 1989 |
[The stiff-man syndrome].
Topics: Baclofen; Diazepam; Humans; Muscle Rigidity; Muscle Spasticity; Syndrome; Valproic Acid | 1987 |
Management of spasticity.
Topics: Baclofen; Dantrolene; Diazepam; Electric Stimulation Therapy; Humans; Injections, Spinal; Muscle Spa | 1988 |
14 trials available for diazepam and Clasp-Knife Spasticity
| Article | Year |
|---|---|
The efficacy of diazepam in enhancing motor function in children with spastic cerebral palsy.
Topics: Analysis of Variance; Cerebral Palsy; Child; Child, Preschool; Diazepam; Dose-Response Relationship, | 2005 |
Reflex cervical muscle spasm: treatment by diazepam, phenobarbital or placebo.
Topics: Adult; Clinical Trials as Topic; Diazepam; Double-Blind Method; Electromyography; Female; Humans; Ma | 1983 |
A new skeletal muscle relaxant (DS 103-282) compared to diazepam in the treatment of muscle spasm of local origin.
Topics: Adult; Aged; Back Pain; Clinical Trials as Topic; Clonidine; Diazepam; Double-Blind Method; Female; | 1981 |
Cyclobenzaprine in intractable pain syndromes with muscle spasm.
Topics: Adult; Amitriptyline; Clinical Trials as Topic; Diazepam; Dibenzocycloheptenes; Female; Humans; Male | 1978 |
Comparison of dantrolene sodium and diazepam in the treatment of spasticity.
Topics: Clinical Trials as Topic; Dantrolene; Diazepam; Humans; Hydantoins; Multiple Sclerosis; Muscle Spast | 1976 |
Medical treatment for spasticity in children with cerebral palsy.
Topics: Cerebral Palsy; Child; Child, Preschool; Clinical Trials as Topic; Dantrolene; Diazepam; Female; Hum | 1976 |
Ketazolam once daily for spasticity: double-blind cross-over study.
Topics: Acute Disease; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Clinical Trials as Topic; Di | 1986 |
A multi-centre, double-blind trial of tizanidine, a new antispastic agent, in spasticity associated with hemiplegia.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Clonidine; Diazepam; Double-Blind Method; Female; | 1988 |
Baclofen versus diazepam for the treatment of spasticity and long-term follow-up of baclofen therapy.
Topics: Adult; Baclofen; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female; Follow-Up Studies; | 1985 |
A comparative trial of dimethothiazine in spastic conditions.
Topics: Activities of Daily Living; Adolescent; Adult; Aged; Cerebrovascular Disorders; Clinical Trials as T | 1974 |
A comparison of dantrolene sodium and diazepam in the treatment of spasticity.
Topics: Adolescent; Adult; Aged; Cerebrovascular Disorders; Clinical Trials as Topic; Dantrolene; Diazepam; | 1974 |
A new agent for the control of spasticity.
Topics: Amines; Clinical Trials as Topic; Diazepam; Electromyography; Humans; Muscle Spasticity; Muscle Tonu | 1970 |
Evaluation of the effect of diazepam on spasticity.
Topics: Adult; Aged; Diazepam; Double-Blind Method; Drug Evaluation; Female; Humans; Male; Middle Aged; Moto | 1967 |
A double blind, cross-over trial of Valium in the treatment of spasticity.
Topics: Amobarbital; Diazepam; Evaluation Studies as Topic; Female; Humans; Male; Muscle Spasticity; Placebo | 1972 |
62 other studies available for diazepam and Clasp-Knife Spasticity
| Article | Year |
|---|---|
5-Aryl-3-(alkylthio)-4H-1,2,4-triazoles as selective antagonists of strychnine-induced convulsions and potential antispastic agents.
Topics: Animals; Anticonvulsants; Cerebellum; Cerebral Cortex; Chlorides; Electroshock; Flumazenil; Male; Mi | 1994 |
Management of high-dose intrathecal baclofen pump explant: A case report.
Topics: Amyotrophic Lateral Sclerosis; Baclofen; Chronic Pain; Diazepam; Humans; Infusion Pumps, Implantable | 2023 |
Surgical treatment for atlantoaxial rotatory fixation in an adult with spastic torticollis: A case report.
Topics: Atlanto-Axial Joint; Botulinum Toxins, Type A; Diazepam; Humans; Joint Dislocations; Male; Middle Ag | 2020 |
Delirium tremens in an AUD patient after an intrathecal baclofen pump induced total alcohol abstinence.
Topics: Alcohol Abstinence; Alcohol Drinking; Alcohol Withdrawal Delirium; Alcoholism; Baclofen; Diazepam; H | 2018 |
Pharmacological management of abnormal tone and movement in cerebral palsy.
Topics: Adolescent; Baclofen; Botulinum Toxins; Cerebral Palsy; Child; Child Health Services; Child, Prescho | 2019 |
Generalised tetanus in an unvaccinated adult.
Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents; Clostridium tetani; Diazepam; Humans; Magnesium | 2010 |
[ON THE CLINICAL ASPECTS AND THERAPY OF PYRAMIDAL AND EXTRAPYRAMIDAL MOVEMENT DISORDERS].
Topics: Athetosis; Basal Ganglia Diseases; Cerebral Palsy; Child; Chorea; Diazepam; Extrapyramidal Tracts; H | 1963 |
[CURRENT PROBLEMS OF SPASTIC PARALYSIS OF THE EXTREMITIES].
Topics: Adolescent; Cerebral Palsy; Child; Diazepam; Electromyography; Handwriting; Muscle Spasticity; Paral | 1963 |
THE USE OF DIAZEPAM IN HEMIPLEGIA.
Topics: Chlordiazepoxide; Diazepam; Hemiplegia; Humans; Muscle Cramp; Muscle Spasticity; Paralysis; Pharmaco | 1964 |
CONTROL OF SPASTIC STATES IN NEUROLOGICAL PATIENTS WITH DIAZEPAM.
Topics: Biomedical Research; Brain Diseases; Brain Neoplasms; Central Nervous System Diseases; Diazepam; Dru | 1965 |
[CLINICAL AND ELECTROMYOGRAPHIC STUDIES IN 110 PATIENTS TREATED WITH A BENZODIAZEPINE DERIVATIVE].
Topics: Benzodiazepines; Diazepam; Drug Therapy; Electromyography; Humans; Muscle Spasticity; Paralysis; Spa | 1964 |
[CLINICAL EXAMINATION OF THE MUSCLE RELAXANT EFFECT OF VALIUM "ROCHE" IN SPASTIC PATIENTS].
Topics: Diazepam; Drug Therapy; Humans; Movement Disorders; Muscle Spasticity; Physical Examination; Spasm | 1964 |
Unexpected benefit of propofol in stiff-person syndrome.
Topics: Aged; Autoantibodies; Baclofen; Diazepam; Drug Resistance; Female; GABA Agonists; GABA-A Receptor Ag | 2008 |
Propofol for stiff-person syndrome: learning new tricks from an old dog.
Topics: Aged; Autoantibodies; Baclofen; Diazepam; Drug Resistance; Female; GABA Agonists; GABA-A Receptor Ag | 2008 |
CGS 8216, Ro 15-1788 and methyl-beta-carboline-3-carboxylate, but not EMD 41717 antagonize the muscle relaxant effect of diazepam in genetically spastic rats.
Topics: Animals; Benzodiazepinones; Carbolines; Convulsants; Diazepam; Electromyography; Female; Flumazenil; | 1984 |
Management of spasticity on neurophysiological basis.
Topics: Baclofen; Chlorpromazine; Cryosurgery; Curare; Dantrolene; Diazepam; Humans; Moxisylyte; Muscle Spas | 1980 |
Drug therapy: spasticity (first of two parts).
Topics: Baclofen; Dantrolene; Diazepam; Humans; Motor Neurons; Muscle Contraction; Muscle Spasticity; Muscle | 1981 |
[Selective pharmacological correction of muscle tonus during rehabilitation of stroke patients].
Topics: Adult; Cerebrovascular Disorders; Diazepam; Drug Combinations; Humans; Middle Aged; Muscle Spasticit | 1984 |
Effect of aminophylline on muscle relaxant action of diazepam and phenobarbitone in genetically spastic rats: further evidence for a purinergic mechanism in the action of diazepam.
Topics: Aminophylline; Animals; Carbolines; Diazepam; Drug Interactions; Electromyography; Female; Male; Mus | 1984 |
The drug treatment of spasticity.
Topics: Baclofen; Clonidine; Dantrolene; Diazepam; Humans; Muscle Spasticity; Parasympatholytics | 1983 |
Postoperative spasticity and shivering. A review with personal observations of 500 patients.
Topics: Adult; Anesthesia, Inhalation; Diazepam; Female; Gallamine Triethiodide; Halothane; Humans; Intraope | 1984 |
Black widow spider bite.
Topics: Antivenins; Black Widow Spider; Calcium Gluconate; Diazepam; Humans; Hypertension; Methocarbamol; Mu | 1984 |
Effect of diazepam and desmethyldiazepam in spasticity and rigidity. A quantitative study of reflexes and plasma concentrations.
Topics: Adult; Diazepam; Female; Humans; Injections, Intravenous; Male; Middle Aged; Muscle Rigidity; Muscle | 1980 |
Medical treatment of spasticity.
Topics: Baclofen; Dantrolene; Diazepam; Humans; Injections, Spinal; Mephenesin; Muscle Relaxants, Central; M | 1980 |
Antispastic medication.
Topics: Baclofen; Dantrolene; Diazepam; Humans; Muscle Spasticity | 1980 |
Discriminative electrophysiological tests to study the mode of action of myorelaxant drugs.
Topics: Anti-Anxiety Agents; Baclofen; Benzodiazepines; Benzodiazepinones; Diazepam; Electrophysiology; Huma | 1982 |
Managing spasticity.
Topics: Adult; Baclofen; Child, Preschool; Cold Temperature; Dantrolene; Diazepam; Female; Humans; Muscle Sp | 1982 |
Management of pediatric spasticity.
Topics: Baclofen; Child; Child, Preschool; Dantrolene; Diazepam; Humans; Infant; Muscle Spasticity; Occupati | 1982 |
Interaction between phenytoin and diazepam in mutant Han-Wistar rats with progressive spastic paresis.
Topics: Animals; Diazepam; Drug Interactions; Electromyography; Female; Male; Muscle Spasticity; Muscles; Pa | 1982 |
Pharmacologic and surgical therapy for spasticity.
Topics: Baclofen; Dantrolene; Diazepam; Humans; Muscle Spasticity; Spinal Cord | 1981 |
[When and how to prescribe muscle relaxants in spasticity ?].
Topics: Baclofen; Dantrolene; Diazepam; Humans; Muscle Relaxants, Central; Muscle Spasticity | 1981 |
[Drug therapy of spasticity].
Topics: Baclofen; Diazepam; Humans; Muscle Spasticity | 1981 |
The female urethral syndrome: external sphincter spasm as etiology.
Topics: Adult; Diazepam; Female; Humans; Muscle Spasticity; Syndrome; Urethral Diseases; Urination Disorders | 1980 |
Factors affecting spasticity.
Topics: Diazepam; Electromyography; Humans; Leg; Motor Neurons; Movement; Muscle Contraction; Muscle Spastic | 1980 |
Diazepam and body weight in myelopathy patients.
Topics: Adult; Aged; Aged, 80 and over; Diazepam; Dose-Response Relationship, Drug; Female; Humans; Male; Mi | 1995 |
Stiff-man syndrome: case report.
Topics: Adult; Diagnosis, Differential; Diazepam; Female; GABA Modulators; Humans; Low Back Pain; Muscle Rel | 1995 |
Pain management for children following selective dorsal rhizotomy.
Topics: Adolescent; Adult; Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Bupiva | 1994 |
Effect of the beta-carboline abecarnil on spinal reflexes in mice and on muscle tone in genetically spastic rats: a comparison with diazepam.
Topics: Animals; Anticonvulsants; Carbolines; Diazepam; Disease Models, Animal; Electromyography; Female; Ma | 1993 |
Involuntary tonic spasms of a limb due to a brain stem lacunar infarction.
Topics: Aged; Brain Stem; Cerebral Infarction; Diazepam; Electroencephalography; Hemiplegia; Humans; Leg; Ma | 1994 |
Clinical assessment of spasticity in spinal cord injury: a multidimensional problem.
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Baclofen; Diazepam; Female; Humans; Male | 1996 |
Diazepam usage in veterans with spinal cord injury.
Topics: Baclofen; Data Collection; Diazepam; Hospitals, Veterans; Humans; Muscle Relaxants, Central; Muscle | 1997 |
Anesthetic management of conray toxicity.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Cerebrospinal Fluid Shunts; Child; Diazepam; Female | 1978 |
Diazepam effect on reflex activity in patients with complete spinal lesions and in those with other causes of spasticity.
Topics: Achilles Tendon; Action Potentials; Adult; Diazepam; Female; H-Reflex; Humans; Male; Middle Aged; Mu | 1977 |
Clinical management of spastic states.
Topics: Baclofen; Dantrolene; Diazepam; Humans; Muscle Spasticity; Neurosurgery; Propylene Glycols; Sclerosi | 1976 |
Pathophysiology and treatment of spasticity: report of two cases.
Topics: Adult; Arachnoiditis; Baclofen; Diazepam; Female; Humans; Male; Muscle Spasticity; Paraplegia; Tuber | 1992 |
[Antispastic treatment of paraplegic patients].
Topics: Baclofen; Contracture; Dantrolene; Diazepam; Humans; Muscle Spasticity; Nursing Care; Paraplegia | 1988 |
The physiology of spasticity and its response to therapy.
Topics: Animals; Baclofen; Central Nervous System Diseases; Dantrolene; Diazepam; Humans; Motor Neurons; Mus | 1988 |
N-desmethyldiazepam physical dependence in dogs.
Topics: Analysis of Variance; Animals; Body Weight; Diazepam; Dogs; Drinking; Energy Intake; Female; Lorazep | 1985 |
[Antispastic agents].
Topics: Adult; Baclofen; Benzodiazepines; Child; Dantrolene; Diazepam; Drug Tolerance; Humans; Muscle Spasti | 1986 |
Electrophysiological analysis of the mode of action of muscle relaxants in spasticity.
Topics: Baclofen; Clonidine; Diazepam; Electrophysiology; Ethanolamines; Female; Humans; Male; Middle Aged; | 1985 |
[Spasticity and its treatment].
Topics: Baclofen; Diazepam; Humans; Muscle Spasticity | 1985 |
The use of diazepam for conservative dentistry in handicapped children.
Topics: Anesthesia, Dental; Anesthesia, Intravenous; Child; Dentistry, Operative; Diazepam; Disabled Persons | 1970 |
[Therapy of spastic syndromes].
Topics: Carisoprodol; Chlordiazepoxide; Chlormezanone; Chlorzoxazone; Curare; Diazepam; Guaifenesin; Humans; | 1969 |
[Modification of the clonus and T-reflex potential by myotonolytica in consideration of the effect of Jendrassik's maneuver. Electromyographic studies in spastic paralysis].
Topics: Diazepam; Dioxins; Electromyography; Humans; Mephenesin; Methyl Ethers; Muscle Spasticity; Parasympa | 1972 |
Neurophysiologic mechanisms of hemiplegic and paraplegic spasticity: implications for therapy.
Topics: Ankle; Dantrolene; Diazepam; Electromyography; Hemiplegia; Humans; Knee; Motor Neurons; Muscle Relax | 1974 |
An electromyographic study of spastic limbs.
Topics: Adult; Aged; Diazepam; Electromyography; Female; Hemiplegia; Humans; Leg; Male; Middle Aged; Muscle | 1973 |
A comparison of baclofen and diazepam in the treatment of spasticity.
Topics: Adult; Aminobutyrates; Body Weight; Chlorine; Diazepam; Female; Humans; Male; Middle Aged; Multiple | 1974 |
[Treatment of spasticity in paraplegia. A new muscle relaxant Ciba 34'647-Ba].
Topics: Amines; Chemical Phenomena; Chemistry; Diazepam; Female; Humans; Male; Muscle Relaxants, Central; Mu | 1972 |
[Studies on spasticity. I. Diazepam in the treatment of spasticity. Considerations on its management in clinical practice and neurological rehabilitation].
Topics: Diazepam; Humans; Muscle Relaxants, Central; Muscle Spasticity; Paraplegia; Spinal Cord Injuries | 1969 |
The use of drugs in the treatment of spasticity.
Topics: Chlordiazepoxide; Curare; Diazepam; Electromyography; Humans; Mephenesin; Muscle Spasticity; Orphena | 1970 |
Spasticity and its amelioration.
Topics: Animals; Anxiety; Defecation; Diazepam; Dogs; Electromyography; Hemiplegia; Humans; Locomotion; Musc | 1970 |
[Drug therapy of spinal spasms].
Topics: Adolescent; Adult; Diazepam; Female; Humans; Male; Middle Aged; Muscle Spasticity; Paraplegia; Spina | 1965 |