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diazepam and Cirrhoses, Experimental Liver

diazepam has been researched along with Cirrhoses, Experimental Liver in 1 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Research Excerpts

ExcerptRelevanceReference
" When animals are pretreated with this hepatotoxic agent, a significant prolongation in plasma half-life of diazepam is observed, due more to an increase in volume of distribution rather than to a decrease in clearance."1.28Pharmacokinetics of diazepam in the rat: influence of an experimentally induced hepatic injury. ( Diaz-Garcia, JM; Fos Galve, D; Oliver-Botana, J, 1991)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Diaz-Garcia, JM1
Oliver-Botana, J1
Fos Galve, D1

Other Studies

1 other study available for diazepam and Cirrhoses, Experimental Liver

ArticleYear
Pharmacokinetics of diazepam in the rat: influence of an experimentally induced hepatic injury.
    European journal of drug metabolism and pharmacokinetics, 1991, Volume: Spec No 3

    Topics: Administration, Oral; Animals; Blood Proteins; Carbon Tetrachloride Poisoning; Diazepam; Erythrocyte

1991