diazepam and Chronic Kidney Failure
diazepam has been researched along with Chronic Kidney Failure in 13 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"A 56-year-old man developed allergic interstitial nephritis and deterioration of preexisting chronic renal failure after receiving diazepam." | 7.67 | Allergic interstitial nephritis due to diazepam. ( McLaughlin, K; Sadjadi, SA; Shah, RM, 1987) |
"The effect of chronic renal disease on the serum free fraction of phenytoin, diazepam and propranolol was examined in vitro among 60 conservatively treated patients with renal insufficiency of varying degree and different etiology, and in 10 patients with a nephrotic syndrome." | 3.67 | Serum protein binding of phenytoin, diazepam and propranolol in chronic renal diseases. ( Neuvonen, PJ; Tallgren, LG; Tiula, E, 1987) |
"A 56-year-old man developed allergic interstitial nephritis and deterioration of preexisting chronic renal failure after receiving diazepam." | 3.67 | Allergic interstitial nephritis due to diazepam. ( McLaughlin, K; Sadjadi, SA; Shah, RM, 1987) |
"The plasma protein binding of diazepam and lidocaine was measured in patients with renal disease (those with uremia, nephrotic syndrome, or who had received a transplant) and in age- and sex- matched control subjects." | 3.66 | Diazepam and lidocaine plasma protein binding in renal disease. ( Davis, D; Grossman, SH; Kitchell, BB; Routledge, PA; Shand, DG, 1982) |
" Uremic toxins were also incubated with purified human albumin, and dose-response experiments with the two most toxic agents in terms of protein damage (guanidine and guanidinopropionic acid) were carried out." | 1.32 | Plasma protein aspartyl damage is increased in hemodialysis patients: studies on causes and consequences. ( D'Aniello, A; De Santo, NG; Galletti, P; Ingrosso, D; Lombardi, C; Perna, AF; Satta, E, 2004) |
" Pharmacokinetic variable values in elderly subjects did not differ in a clinically significant manner from those in younger subjects." | 1.28 | Pharmacokinetics of misoprostol in the elderly, in patients with renal failure and when coadministered with NSAID or antipyrine, propranolol or diazepam. ( Karim, A; Nicholson, PA; Smith, M, 1990) |
"5 patients with chronic renal failure on maintenance hemodialysis and 5 healthy matched controls received single 20-mg intravenous doses of clorazepate dipotassium." | 1.27 | Clorazepate dipotassium and diazepam in renal insufficiency: serum concentrations and protein binding of diazepam and desmethyldiazepam. ( Greenblatt, DJ; Kaschell, HJ; Ochs, HR; Rauh, HW, 1984) |
Research
Studies (13)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 9 (69.23) | 18.7374 |
1990's | 2 (15.38) | 18.2507 |
2000's | 2 (15.38) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Perna, AF | 1 |
Ingrosso, D | 1 |
Satta, E | 1 |
Lombardi, C | 1 |
Galletti, P | 1 |
D'Aniello, A | 1 |
De Santo, NG | 1 |
Nishio, T | 1 |
Takamura, N | 1 |
Nishii, R | 1 |
Tokunaga, J | 1 |
Yoshimoto, M | 1 |
Kawai, K | 1 |
Ochs, HR | 1 |
Rauh, HW | 1 |
Greenblatt, DJ | 2 |
Kaschell, HJ | 1 |
Gulyassy, PF | 1 |
Depner, TA | 1 |
Grossman, SH | 1 |
Davis, D | 1 |
Kitchell, BB | 1 |
Shand, DG | 1 |
Routledge, PA | 1 |
Both, R | 1 |
Mühlau, G | 1 |
Neumann, J | 1 |
Sperschneider, H | 1 |
Stein, G | 1 |
Taclob, L | 1 |
Needle, M | 1 |
Harmatz, JS | 1 |
Shader, RI | 1 |
Owada, S | 1 |
Toyama, K | 1 |
Maeba, T | 1 |
Ishida, M | 1 |
Nicholson, PA | 1 |
Karim, A | 1 |
Smith, M | 1 |
Pacifici, GM | 1 |
Viani, A | 1 |
Rizzo, G | 1 |
Carrai, M | 1 |
Tiula, E | 1 |
Tallgren, LG | 1 |
Neuvonen, PJ | 1 |
Sadjadi, SA | 1 |
McLaughlin, K | 1 |
Shah, RM | 1 |
Reviews
1 review available for diazepam and Chronic Kidney Failure
Article | Year |
---|---|
Impaired binding of drugs and endogenous ligands in renal diseases.
Topics: Apazone; Bilirubin; Binding Sites; Carrier Proteins; Diazepam; Digitoxin; Fatty Acids, Nonesterified | 1983 |
Trials
1 trial available for diazepam and Chronic Kidney Failure
Article | Year |
---|---|
Influences of haemodialysis on the binding sites of human serum albumin: possibility of an efficacious administration plan using binding inhibition.
Topics: Adult; Aged; Barbiturates; Binding Sites; Carbon Radioisotopes; Diazepam; Diuretics; Fatty Acids, No | 2008 |
Other Studies
11 other studies available for diazepam and Chronic Kidney Failure
Article | Year |
---|---|
Plasma protein aspartyl damage is increased in hemodialysis patients: studies on causes and consequences.
Topics: Asparagine; Aspartic Acid; Biomarkers; Blood Chemical Analysis; Blood Proteins; Diazepam; Female; Hu | 2004 |
Clorazepate dipotassium and diazepam in renal insufficiency: serum concentrations and protein binding of diazepam and desmethyldiazepam.
Topics: Adult; Aged; Anti-Anxiety Agents; Clorazepate Dipotassium; Diazepam; Dose-Response Relationship, Dru | 1984 |
Diazepam and lidocaine plasma protein binding in renal disease.
Topics: Adult; Aged; Blood Proteins; Diazepam; Fatty Acids, Nonesterified; Female; Humans; Kidney Diseases; | 1982 |
[The problem of the so-called dialysis encephalopathy].
Topics: Adolescent; Adult; Brain Damage, Chronic; Dementia; Diazepam; Electroencephalography; Evoked Potenti | 1982 |
Drug-induced encephalopathy in patients on maintenance haemodialysis.
Topics: Aged; Anti-Anxiety Agents; Arthritis; Coronary Disease; Dementia; Diazepam; Flurazepam; Fractures, B | 1976 |
Sex differences in diazepam protein binding in patients with renal insufficiency.
Topics: Adolescent; Adult; Age Factors; Aged; Creatinine; Diazepam; Female; Humans; Kidney Failure, Chronic; | 1978 |
[Uremic pruritus in chronic kidney failure with hemodialysis].
Topics: Diazepam; Histamine; Histamine Antagonists; Humans; Kidney Failure, Chronic; Lidocaine; Parathyroide | 1992 |
Pharmacokinetics of misoprostol in the elderly, in patients with renal failure and when coadministered with NSAID or antipyrine, propranolol or diazepam.
Topics: Adult; Aged; Aging; Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Diazepam; Drug | 1990 |
Plasma protein binding of ethinyloestradiol: effect of disease and interaction with drugs.
Topics: Adult; Aged; Blood Proteins; Diazepam; Digitoxin; Drug Interactions; Ethinyl Estradiol; Female; Huma | 1989 |
Serum protein binding of phenytoin, diazepam and propranolol in chronic renal diseases.
Topics: Creatinine; Diazepam; Humans; Kidney Failure, Chronic; Nephrotic Syndrome; Orosomucoid; Phenytoin; P | 1987 |
Allergic interstitial nephritis due to diazepam.
Topics: Diazepam; Drug Hypersensitivity; Eosinophilia; Eosinophils; Humans; Kidney Failure, Chronic; Male; M | 1987 |