diazepam has been researched along with Chronic Insomnia in 66 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In addition, a dose-response effect was seen with Org 3770, 15 mg seeming optimal." | 6.66 | A double-blind group comparative study using the new anti-depressant Org 3770, placebo and diazepam in patients with expected insomnia and anxiety before elective gynaecological surgery. ( Bettum, V; Dunbar, GC; Jørgensen, J; Steffensen, K; Sørensen, M; Viby-Mogensen, J, 1985) |
| " He developed neuroleptic malignant syndrome (NMS) which was treated successfully with intravenous diazepam." | 3.69 | Catatonic syndrome following recovery from neuroleptic malignant syndrome. ( Dent, J, 1995) |
| " Regular daily dosing with most benzodiazepines leads to drug accumulation which is proportional to the elimination half-life." | 2.66 | Benzodiazepine hypnotics in the elderly. ( Cook, PJ, 1986) |
| " In addition, a dose-response effect was seen with Org 3770, 15 mg seeming optimal." | 2.66 | A double-blind group comparative study using the new anti-depressant Org 3770, placebo and diazepam in patients with expected insomnia and anxiety before elective gynaecological surgery. ( Bettum, V; Dunbar, GC; Jørgensen, J; Steffensen, K; Sørensen, M; Viby-Mogensen, J, 1985) |
| "Lormetazepam (Noctamid) at a dosage of 1 mg was compared with diazepam (Valium) at a dosage of 5 mg in a 7-day double-blind study." | 2.65 | Comparative efficacy of lormetazepam (Noctamid) and diazepam (Valium) in 100 out-patients with insomnia. ( Fichte, K; Hentschel, HD; Sastre y Hernández, MS, 1981) |
| " Twenty-four anxious inpatients were treated with diazepam, amylobarbitone sodium and placebo in flexible dosage for 1 week." | 2.65 | A comparison of the clinical and psychological effects of diazepam and amylobarbitone in anxious patients. ( Lader, M; Tansella, CZ; Tansella, M, 1979) |
| " 4 Compared with diazepam the tested drug has a longer plasma apparent half-life and a lower relative clearance." | 2.64 | Pharmacokinetics of N-demethyldiazepam in patients suffering from insomnia and treated with nortriptyline. ( Alberti, GG; De Maio, D; Franciosi, P; Gomeni, R; Scieghi, G; Tognoni, G, 1975) |
| "Onset at age 76, association with insomnia and a rapid course leading to death within 2 years were the characteristic features." | 2.38 | [Stiff-Man syndrome with late onset]. ( Catanzariti, JF; Hurtevent, JF; Pasquier, F; Petit, H; Vermersch, P, 1992) |
| "Those disorders discussed are attention deficit disorder, conduct disorders, anxiety disorders, sleep disorders, schizophrenia, autism, Tourette's syndrome, mental retardation, depressive illness, manic depressive illness, eating disorders, and enuresis." | 2.37 | Pharmacologic treatment of psychiatric and neurodevelopmental disorders in children and adolescents (Part 1). ( McDaniel, KD, 1986) |
| "The mean Athens Insomnia Scale score decreased over 3 months after switching to lemborexant (1 mo: -2." | 1.91 | Switching to lemborexant for the management of insomnia in mental disorders: the SLIM study. ( Goto, M; Hirata, Y; Horikoshi, S; Ichinose, M; Kanno-Nozaki, K; Kobayashi, Y; Miura, I; Suzuki, Y; Watanabe, K; Yabe, H; Yamamoto, S, 2023) |
| "Aged insomnia rat model was established with subcutaneous injection of D-galactose for 42 days and then intraperitoneal injection of para-chlorophenylalanine for 3 days." | 1.56 | Sedative and Hypnotic Effects and Transcriptome Analysis of Polygala tenuifolia in Aged Insomnia Rats. ( Peng, ZP; Ren, XJ; Wang, GY; Wang, QQ; Zhang, XP, 2020) |
| " Occasionally, insomnia-induced debilitations may be remedied by long-term use of sedative/hypnotic drugs; some examples are given." | 1.27 | Specific effects of sedative/hypnotic drugs in the treatment of incapacitating chronic insomnia. ( Regestein, QR, 1987) |
| "For the insomniac without significant psychopathology, temazepam 10-20 mg, triazolam 0." | 1.26 | The use of short- and long-acting hypnotics in clinical medicine. ( Nicholson, AN, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 54 (81.82) | 18.7374 |
| 1990's | 4 (6.06) | 18.2507 |
| 2000's | 3 (4.55) | 29.6817 |
| 2010's | 2 (3.03) | 24.3611 |
| 2020's | 3 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Horikoshi, S | 1 |
| Miura, I | 1 |
| Suzuki, Y | 1 |
| Kobayashi, Y | 1 |
| Hirata, Y | 1 |
| Goto, M | 1 |
| Ichinose, M | 1 |
| Yamamoto, S | 1 |
| Kanno-Nozaki, K | 1 |
| Watanabe, K | 1 |
| Yabe, H | 1 |
| Ren, XJ | 1 |
| Wang, GY | 1 |
| Zhang, XP | 1 |
| Wang, QQ | 1 |
| Peng, ZP | 1 |
| Oliveira, C | 1 |
| Filipe, R | 1 |
| Meira, J | 1 |
| Sampaio, L | 1 |
| Teixeira, L | 1 |
| Rodrigues, J | 1 |
| Nunes, I | 1 |
| Tavares, J | 1 |
| Hirase, M | 1 |
| Ishida, T | 1 |
| Kamei, C | 1 |
| Bum, EN | 2 |
| Taiwe, GS | 1 |
| Nkainsa, LA | 1 |
| Moto, FC | 1 |
| Seke Etet, PF | 1 |
| Hiana, IR | 1 |
| Bailabar, T | 1 |
| Seyni, P | 1 |
| Rakotonirina, A | 1 |
| Rakotonirina, SV | 1 |
| Porecha, S | 1 |
| shah, T | 1 |
| Jogani, V | 1 |
| Naik, S | 1 |
| Misra, A | 1 |
| Morera-Fumero, AL | 1 |
| Abreu-Gonzalez, P | 1 |
| Okomolo, FC | 1 |
| Mbafor, JT | 1 |
| Kouemou, N | 1 |
| Kandeda, AK | 1 |
| Talla, E | 1 |
| Dimo, T | 1 |
| Rakotonirira, A | 1 |
| Rakotonirira, SV | 1 |
| LOVE, J | 1 |
| HARDER, A | 1 |
| AIVAZIAN, GH | 1 |
| DELEMOS, GP | 1 |
| CLEMENT, WR | 1 |
| NICKELS, E | 1 |
| Greenberg, R | 2 |
| Borelli, S | 1 |
| Schellert, P | 1 |
| Sastre y Hernández, MS | 1 |
| Hentschel, HD | 1 |
| Fichte, K | 1 |
| Lapierre, YD | 1 |
| Nicholson, AN | 2 |
| Greenblatt, DJ | 1 |
| Shader, RI | 1 |
| Abernethy, DR | 1 |
| Conell, LJ | 1 |
| Berlin, RM | 1 |
| Harris, PG | 1 |
| Viukari, M | 1 |
| Miettinen, P | 1 |
| Pearlman, T | 1 |
| Mellor, CS | 1 |
| Jain, VK | 1 |
| Ladewig, D | 1 |
| Gertner, E | 1 |
| Marshall, PS | 1 |
| Filandrinos, D | 1 |
| Potek, AS | 1 |
| Smith, TM | 1 |
| Pollak, CP | 1 |
| Perlick, D | 1 |
| Linsner, JP | 1 |
| Dent, J | 1 |
| Lasserre, E | 1 |
| Coccagna, G | 1 |
| Lugaresi, E | 1 |
| Cesco, G | 1 |
| Giannico, S | 1 |
| Fabbruci, I | 1 |
| Scaggiante, L | 1 |
| Montanaro, N | 1 |
| Tansella, CZ | 1 |
| Tansella, M | 2 |
| Lader, M | 1 |
| MacPhail, I | 1 |
| Ogilvie, WA | 1 |
| Purvis, CR | 1 |
| Tennant, FS | 1 |
| Middleton, RS | 1 |
| Tognoni, G | 2 |
| Gomeni, R | 1 |
| De Maio, D | 1 |
| Alberti, GG | 1 |
| Franciosi, P | 1 |
| Scieghi, G | 1 |
| Siciliani, O | 1 |
| Burti, L | 1 |
| Schiavon, M | 1 |
| Zimmermann, C | 1 |
| Gerna, M | 1 |
| Morselli, PL | 1 |
| Vermersch, P | 1 |
| Hurtevent, JF | 1 |
| Pasquier, F | 1 |
| Catanzariti, JF | 1 |
| Petit, H | 1 |
| McDaniel, KD | 1 |
| Regestein, QR | 1 |
| Rapport, DJ | 1 |
| Covington, EC | 1 |
| Fancourt, G | 1 |
| Castleden, M | 1 |
| Cook, PJ | 1 |
| Crea, L | 1 |
| Aguglia, E | 1 |
| Bergman, U | 1 |
| Griffiths, RR | 1 |
| Kok, LP | 1 |
| Tsoi, WF | 1 |
| Fleming, JA | 1 |
| Rungta, K | 1 |
| Isomura, T | 1 |
| McMillan, MJ | 1 |
| Sørensen, M | 1 |
| Jørgensen, J | 1 |
| Viby-Mogensen, J | 1 |
| Bettum, V | 1 |
| Dunbar, GC | 1 |
| Steffensen, K | 1 |
| Tosi, GC | 1 |
| Tosi, EC | 1 |
| Hattab, JR | 1 |
| Borenstein, P | 1 |
| Champion, C | 1 |
| Cujo, P | 1 |
| Gekière, F | 1 |
| Olivenstein, C | 1 |
| Kramarz, P | 1 |
| Pearlman, CA | 1 |
| Cobb, J | 1 |
| Reyntjens, AM | 1 |
| Van Mierlo, FP | 1 |
| Ananth, JV | 1 |
| Bronheim, LA | 1 |
| Klingner, A | 1 |
| Ban, TA | 1 |
| Hall, RC | 1 |
| Joffe, JR | 1 |
| Dasberg, HH | 1 |
| van der Kleijn, E | 1 |
| Guelen, JP | 1 |
| van Praag, HM | 1 |
| Kaneko, J | 1 |
| Takaishi, N | 1 |
| Ida, H | 1 |
| Abe, H | 1 |
| Hosaka, M | 1 |
| Clift, AD | 1 |
| Franke, KH | 1 |
| Vittadini, G | 1 |
| Canubi, A | 1 |
| Pietrobono, P | 1 |
| Venchi, G | 1 |
| Scotti, A | 1 |
| Ledoux, G | 1 |
| Jacquet, J | 1 |
| Lehembre, P | 1 |
4 reviews available for diazepam and Chronic Insomnia
| Article | Year |
|---|---|
Drug therapy. Current status of benzodiazepines.
Topics: Alcoholic Beverages; Alcoholism; Anesthetics; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Bone Di | 1983 |
[Stiff-Man syndrome with late onset].
Topics: Aged; Diazepam; Electromyography; Female; GABA Antagonists; Humans; Polysomnography; Sleep Initiatio | 1992 |
Pharmacologic treatment of psychiatric and neurodevelopmental disorders in children and adolescents (Part 1).
Topics: Adolescent; Aggression; Antidepressive Agents; Antipsychotic Agents; Anxiety, Separation; Attention | 1986 |
Medical-psychological implications of recent sleep research.
Topics: Adaptation, Psychological; Amphetamine; Barbiturates; Central Nervous System Stimulants; Chloral Hyd | 1970 |
19 trials available for diazepam and Chronic Insomnia
| Article | Year |
|---|---|
[On the efficacy of psychopharmaceutic agents in atopic neurodermatitis: comparative study of diazepam (Valium), promethazine (Phenergan) and placebo].
Topics: Adolescent; Adult; Dermatitis, Atopic; Diazepam; Female; Humans; Male; Middle Aged; Neurodermatitis; | 1967 |
Comparative efficacy of lormetazepam (Noctamid) and diazepam (Valium) in 100 out-patients with insomnia.
Topics: Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Diazepam; Double-Blind | 1981 |
The role of general practitioner research groups in the study of benzodiazepines.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety; Clinical Trials as Topic; Clorazepate Dipotas | 1983 |
Single-blind evaluation of hypnotic activity of chlordesmethyldiazepam in No-placebo-reactor medical patients.
Topics: Clinical Trials as Topic; Diazepam; Drug Evaluation; Female; Humans; Hypnotics and Sedatives; Male; | 1977 |
A comparison of the clinical and psychological effects of diazepam and amylobarbitone in anxious patients.
Topics: Adult; Amobarbital; Anxiety; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female; Humans | 1979 |
Comparison of diazepam and flurazepam in the treatment of insomnia in general practice.
Topics: Administration, Oral; Adolescent; Adult; Aged; Capsules; Clinical Trials as Topic; Diazepam; Double- | 1979 |
Temazepam (Euhypnos) and chlormethiazole: a comparative study in geriatric patients.
Topics: Aged; Chlormethiazole; Diazepam; Drug Evaluation; Female; Humans; Male; Middle Aged; Sleep Initiatio | 1978 |
Pharmacokinetics of N-demethyldiazepam in patients suffering from insomnia and treated with nortriptyline.
Topics: Adult; Aged; Clinical Trials as Topic; Diazepam; Drug Evaluation; Drug Therapy, Combination; Half-Li | 1975 |
N-desmethyldiazepam and amylobarbitone sodium as hypnotics in anxious patients. Plasma levels, clinical efficacy and residual effects.
Topics: Adult; Amobarbital; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Female; Humans; Hypnotics | 1975 |
Benzodiazepine hypnotics in the elderly.
Topics: Aged; Anti-Anxiety Agents; Clinical Trials as Topic; Diazepam; Dose-Response Relationship, Drug; Dou | 1986 |
Comparison of midazolam, diazepam and placebo in the treatment of insomnia.
Topics: Adult; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female; Humans; Male; Midazolam; Mid | 1986 |
A double-blind group comparative study using the new anti-depressant Org 3770, placebo and diazepam in patients with expected insomnia and anxiety before elective gynaecological surgery.
Topics: Adult; Anxiety; Blood Pressure; Diazepam; Dibenzazepines; Dose-Response Relationship, Drug; Double-B | 1985 |
The use of N-demethyldiazepam in outpatients suffering from insomnia.
Topics: Adult; Aged; Ambulatory Care; Clinical Trials as Topic; Consumer Behavior; Diazepam; Evaluation Stud | 1973 |
[An original psychotropic drug: sulpiride].
Topics: Adult; Animals; Anxiety; Behavior; Clinical Trials as Topic; Cognition Disorders; Delirium; Depressi | 1969 |
A comparative double-blind trial of pimozide in stress-induced psychic and functional disorders.
Topics: Administration, Oral; Adult; Aged; Anxiety Disorders; Clinical Trials as Topic; Depression; Diazepam | 1972 |
Diazepam in the treatment of insomnia in psychiatric patients.
Topics: Adult; Chloral Hydrate; Clinical Trials as Topic; Diazepam; Female; Humans; Hypnotics and Sedatives; | 1973 |
[Clinical effect of nitrazepam on psychoneurosis with insomnia].
Topics: Adolescent; Adult; Benzazepines; Clinical Trials as Topic; Diazepam; Female; Humans; Male; Middle Ag | 1969 |
Factors leading to dependence on hypnotic drugs.
Topics: Amobarbital; Benzazepines; Diazepam; Family Practice; Female; Glutethimide; Humans; Hypnotics and Se | 1972 |
[Experiences with a new sleeping preparation (Mogadan "Roche") in neuropsychiatric practice].
Topics: Clinical Trials as Topic; Diazepam; Humans; Mental Disorders; Sleep Initiation and Maintenance Disor | 1965 |
43 other studies available for diazepam and Chronic Insomnia
| Article | Year |
|---|---|
Switching to lemborexant for the management of insomnia in mental disorders: the SLIM study.
Topics: Benzodiazepines; Diazepam; Humans; Hypnotics and Sedatives; Orexin Receptor Antagonists; Retrospecti | 2023 |
Sedative and Hypnotic Effects and Transcriptome Analysis of Polygala tenuifolia in Aged Insomnia Rats.
Topics: Animals; China; Diazepam; Disease Models, Animal; Gene Expression Profiling; Hypnotics and Sedatives | 2020 |
Benzodiazepine Use in Opioid Maintenance Treatment Programme: Risks and Clinical Outcomes.
Topics: Adult; Analgesics, Opioid; Anxiety; Benzodiazepines; Buprenorphine; Cross-Sectional Studies; Diazepa | 2021 |
Rebound insomnia induced by abrupt withdrawal of hypnotics in sleep-disturbed rats.
Topics: Animals; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Sch | 2008 |
Validation of anticonvulsant and sedative activity of six medicinal plants.
Topics: Animals; Anticonvulsants; Convulsants; Diazepam; Dose-Response Relationship, Drug; Electroshock; Epi | 2009 |
Microemulsion based intranasal delivery system for treatment of insomnia.
Topics: Administration, Intranasal; Alprazolam; Animals; Diazepam; Disease Models, Animal; Drug Compounding; | 2009 |
Diazepam discontinuation through agomelatine in schizophrenia with insomnia and depression.
Topics: Acetamides; Adult; Anti-Anxiety Agents; Depression; Diazepam; Humans; Hypnotics and Sedatives; Male; | 2010 |
Evaluation of the sedative and anticonvulsant properties of three Cameroonian plants.
Topics: Administration, Oral; Analysis of Variance; Animals; Anticonvulsants; Cameroon; Diazepam; Dose-Respo | 2011 |
DIAZEPAM IN TREATMENT OF EMOTIONAL DISORDERS.
Topics: Anxiety; Anxiety Disorders; Chlordiazepoxide; Diazepam; Geriatrics; Humans; Mood Disorders; Neurotic | 1963 |
[CLINICAL EXPERIENCES WITH VALIUM ROCHE, A NEW BENZODIAZEPINE DERIVATIVE].
Topics: Antisocial Personality Disorder; Anxiety; Anxiety Disorders; Autonomic Nervous System Diseases; Benz | 1964 |
CLINICAL EVALUATION OF DIAZEPAM.
Topics: Adolescent; Anxiety; Anxiety Disorders; Biomedical Research; Chlordiazepoxide; Diazepam; Drug Therap | 1964 |
EFFECTS OF DIAZEPAM SUSPENSION IN GERIATRIC PATIENTS HOSPITALIZED FOR PSYCHIATRIC ILLNESSES.
Topics: Aged; Biomedical Research; Dementia; Diazepam; Drug Therapy; Geriatrics; Humans; Mental Disorders; P | 1965 |
Dream interruption insomnia.
Topics: Chlordiazepoxide; Diazepam; Dreams; Electrooculography; Humans; Rorschach Test; Sleep; Sleep Initiat | 1967 |
Choice of benzodiazepines.
Topics: Aged; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Diazepam; Flurazepam; Half-Life; Humans; Liver | 1981 |
Benzodiazepine withdrawal.
Topics: Anti-Anxiety Agents; Anxiety; Diazepam; Drug Tolerance; Humans; Lorazepam; Oxazepam; Sleep Initiatio | 1981 |
The use of short- and long-acting hypnotics in clinical medicine.
Topics: Anti-Anxiety Agents; Diazepam; Flunitrazepam; Humans; Hypnotics and Sedatives; Psychomotor Performan | 1981 |
Withdrawal after substitution of a short-acting for a long-acting benzodiazepine.
Topics: Anti-Anxiety Agents; Anxiety; Chronic Disease; Delayed-Action Preparations; Diazepam; Flurazepam; Ha | 1983 |
Diazepam, promethazine and propiomazine as hypnotics in elderly inpatients.
Topics: Aged; Diazepam; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Phenothiazines; | 1984 |
Withdrawal symptoms after long-term treatment with flurazepam.
Topics: Anxiety Disorders; Depressive Disorder; Diazepam; Flurazepam; Humans; Sleep Initiation and Maintenan | 1984 |
Diazepam withdrawal syndrome: its prolonged and changing nature.
Topics: Adult; Anorexia; Diazepam; Female; Humans; Male; Middle Aged; Myoclonus; Perceptual Disorders; Psych | 1982 |
[Does a rebound insomnia following benzodiazepine administration exist?].
Topics: Benzodiazepines; Diazepam; Flunitrazepam; Flurazepam; Humans; Nitrazepam; Sleep Initiation and Maint | 1980 |
Complications resulting from the use of Chinese herbal medications containing undeclared prescription drugs.
Topics: Adult; Aged; Arthritis; Chronic Disease; Depression; Diazepam; Drugs, Chinese Herbal; Female; Gastro | 1995 |
Sleep and motor activity of community elderly who frequently use bedtime medications.
Topics: Aged; Circadian Rhythm; Diazepam; Drug Administration Schedule; Female; Flurazepam; Humans; Hypnotic | 1994 |
Catatonic syndrome following recovery from neuroleptic malignant syndrome.
Topics: Anti-Anxiety Agents; Antipsychotic Agents; Catatonia; Chlorpromazine; Diazepam; Dose-Response Relati | 1995 |
[High altitude insomnia. Efficacy of flunitrazepam].
Topics: Altitude; Anti-Anxiety Agents; Diazepam; Dose-Response Relationship, Drug; Dyspnea; Flunitrazepam; H | 1979 |
Hypnotics today.
Topics: Aged; Anti-Anxiety Agents; Diazepam; Electroencephalography; Humans; Sleep; Sleep Initiation and Mai | 1979 |
[Restless legs syndrome and nightly myocloni].
Topics: Aged; Diazepam; Electromyography; Humans; Middle Aged; Myoclonus; Restless Legs Syndrome; Sleep Init | 1978 |
Outpatient treatment and outcome of prescription drug abuse.
Topics: Adult; Ambulatory Care; Amphetamines; Anxiety; Barbiturates; Counseling; Depression; Diazepam; Drug | 1979 |
Choice of a benzodiazepine for treatment of anxiety or insomnia.
Topics: Anxiety; Benzodiazepines; Chlordiazepoxide; Diazepam; Humans; Oxazepam; Sleep Initiation and Mainten | 1977 |
Temazepam for insomnia?
Topics: Diazepam; Humans; Sleep Initiation and Maintenance Disorders | 1978 |
Specific effects of sedative/hypnotic drugs in the treatment of incapacitating chronic insomnia.
Topics: Adult; Aged; Diazepam; Female; Humans; Hydromorphone; Hypnotics and Sedatives; Male; Methaqualone; P | 1987 |
Motor phenomena in benzodiazepine withdrawal.
Topics: Aged; Alprazolam; Anti-Anxiety Agents; Diagnosis, Differential; Diazepam; Drug Therapy, Combination; | 1989 |
The use of benzodiazepines with particular reference to the elderly.
Topics: Aged; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Diazepam; Humans; Infusions, Parenteral; Kinet | 1986 |
[Clinical study of etizolam in patients with anxiety and insomnia].
Topics: Adult; Aged; Anxiety Disorders; Diazepam; Female; Humans; Male; Middle Aged; Psychiatric Status Rati | 1988 |
Relative abuse of diazepam and oxazepam: prescription forgeries and theft/loss reports in Sweden.
Topics: Cross-Sectional Studies; Depressive Disorder; Diazepam; Drug and Narcotic Control; Drug Prescription | 1986 |
Withdrawal regimen for triazolam-dependent patients.
Topics: Diazepam; Flurazepam; Humans; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndr | 1986 |
Stiff man syndrome: is the lesion at spinal cord or brain stem level.
Topics: Adult; Amenorrhea; Anxiety; Barbiturates; Brain Diseases; Brain Stem; Child, Preschool; Depression; | 1974 |
Aberrant response to diazepam: a new syndrome.
Topics: Adult; Aged; Depression; Diazepam; Female; Follow-Up Studies; Humans; Middle Aged; Psychoses, Substa | 1972 |
Benzodiazepines--too many similar compounds?
Topics: Anxiety; Benzazepines; Diazepam; Humans; Sleep Initiation and Maintenance Disorders; Structure-Activ | 1974 |
Plasma concentrations of diazepam and of its metabolite N-desmethyldiazepam in relation to anxiolytic effect.
Topics: Adult; Anxiety; Chromatography, Gas; Dealkylation; Diazepam; Female; Half-Life; Humans; Male; Middle | 1974 |
[The use of diazepam as a sedative in infancy].
Topics: Diazepam; Female; Fever; Humans; Infant; Infant, Newborn; Male; Psychomotor Disorders; Sleep Initiat | 1969 |
[On the use of a new derivative of benzodiazepines (Ro 4-5360) in the treatment of insomnia in pre-surgery patients].
Topics: Anxiety; Diazepam; Glutethimide; Humans; Pentobarbital; Preanesthetic Medication; Preoperative Care; | 1969 |
[Problems raised by the choice of a hypnotic, in open and closed psychiatric wards, while experimenting with Ro.4-5360].
Topics: Diazepam; Humans; Mental Disorders; Pentobarbital; Sleep Initiation and Maintenance Disorders | 1966 |