diazepam has been researched along with Chronic Illness in 109 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Thirty-two patients suffering from osteoarthritis were subjected to electroacupuncture, with or without pretreatment with naloxone or diazepam." | 9.07 | Interaction of diazepam and naloxone on acupuncture induced pain relief. ( Eriksson, SV; Lundeberg, S; Lundeberg, T, 1991) |
| "Thirty out-patients suffering from panic disorders associated with agoraphobia were enrolled in a double-blind, controlled trial to compare the effectiveness and tolerability of etizolam and placebo." | 9.06 | Etizolam versus placebo in the treatment of panic disorder with agoraphobia: a double-blind study. ( Ecari, U; Savoldi, F; Somenzini, G, 1990) |
| "Fifty-seven chronic agoraphobic outpatients were treated by 12 hours of exposure in vivo on four days over two weeks to check the effects of oral diazepam versus placebo during group exposure, group versus individual exposure, and high versus medium anxiety arousal during individual exposure." | 9.04 | Exposure in vivo of agoraphobics: contributions of diazepam, group exposure, and anxiety evocation. ( Hafner, J; Marks, I, 1976) |
| "This is a single institution nonexperimental study intended to analyze the therapeutic efficacy of topical diazepam in treating symptoms of chronic anal fissures." | 7.85 | Increasing efficacy and reducing side effects in treatment of chronic anal fissures: A study of topical diazepam therapy. ( Hang, MTH; Keck, C; Keshavarzian, A; Sedghi, S; Smith, BE, 2017) |
| "Intravenous administration of high doses of lidocaine has been used as a treatment modality for tinnitus." | 7.69 | [The lidocaine test in tinnitus. Determination of its current status]. ( Davis, A; Hörmann, K; Schmidt, H; Stasche, N, 1994) |
| "Pain was rated on visual analogue scales before, during, and after treatment." | 6.67 | A comparative study of diazepam and acupuncture in patients with osteoarthritis pain: a placebo controlled study. ( Eriksson, SV; Lundeberg, T; Thomas, M, 1991) |
| "We present the case of a patient with renal cell carcinoma hospitalized for intractable cough that failed to respond adequately to usual treatments, but improved with diazepam." | 5.35 | The cough from hell: diazepam for intractable cough in a patient with renal cell carcinoma. ( Estfan, B; Walsh, D, 2008) |
| " Thirty-two patients suffering from osteoarthritis were subjected to electroacupuncture, with or without pretreatment with naloxone or diazepam." | 5.07 | Interaction of diazepam and naloxone on acupuncture induced pain relief. ( Eriksson, SV; Lundeberg, S; Lundeberg, T, 1991) |
| "Thirty out-patients suffering from panic disorders associated with agoraphobia were enrolled in a double-blind, controlled trial to compare the effectiveness and tolerability of etizolam and placebo." | 5.06 | Etizolam versus placebo in the treatment of panic disorder with agoraphobia: a double-blind study. ( Ecari, U; Savoldi, F; Somenzini, G, 1990) |
| "Fifty-seven chronic agoraphobic outpatients were treated by 12 hours of exposure in vivo on four days over two weeks to check the effects of oral diazepam versus placebo during group exposure, group versus individual exposure, and high versus medium anxiety arousal during individual exposure." | 5.04 | Exposure in vivo of agoraphobics: contributions of diazepam, group exposure, and anxiety evocation. ( Hafner, J; Marks, I, 1976) |
| "This is a single institution nonexperimental study intended to analyze the therapeutic efficacy of topical diazepam in treating symptoms of chronic anal fissures." | 3.85 | Increasing efficacy and reducing side effects in treatment of chronic anal fissures: A study of topical diazepam therapy. ( Hang, MTH; Keck, C; Keshavarzian, A; Sedghi, S; Smith, BE, 2017) |
| " In acute study, seizures were induced by either pentylenetetrazole (PTZ) injection or maximal electroshock seizures, while in the chronic study, kindling was induced by injecting PTZ (30 mg/kg, s." | 3.76 | Effect of phosphamidon on convulsive behavior and biochemical parameters: modulation by progesterone and 4'-chlorodiazepam in rats. ( Arora, T; Banerjee, BD; Joshi, V; Mahajan, P; Mediratta, PK; Mehta, AK; Mehta, KD; Rathor, N; Sharma, AK; Sharma, KK, 2010) |
| " Housing conditions did not alter the anticonvulsant activity of diazepam or ethanol, although the anticonvulsant effect of ethanol was significantly greater against PTZ-induced seizures." | 3.72 | Sex differences in effects of mild chronic stress on seizure risk and GABAA receptors in rats. ( Chadda, R; Devaud, LL, 2004) |
| "Intravenous administration of high doses of lidocaine has been used as a treatment modality for tinnitus." | 3.69 | [The lidocaine test in tinnitus. Determination of its current status]. ( Davis, A; Hörmann, K; Schmidt, H; Stasche, N, 1994) |
| "Following pilocarpine-induced status epilepticus, rats become chronically epileptic showing 2-3 spontaneous recurrent seizures per week." | 3.69 | Blockade of spreading depression in chronic epileptic rats: reversion by diazepam. ( Cavalheiro, EA; Guedes, RC, 1997) |
| "Review of the treatment of chronic non-bacterial prostatitis, defined by the presence of more than 500 leucocytes per mm3 in the expressed prostatic secretion (EPS), showed symptomatic response after 3 months of minocycline, trimethoprim, co-trimoxazole or diazepam." | 3.66 | Review of results of four regimens for treatment of chronic non-bacterial prostatitis. ( Simmons, PD; Thin, RN, 1983) |
| "The effects of 5 mg of diazepam intravenously were assessed in 23 patients with liver disease, 10 of whom had clinical evidence either in the past or at the time of study of hepatic encephalopathy." | 3.65 | Clinical and electroencephalographic assessment of diazepam in liver disease. ( Knill-Jones, RP; Murray-Lyon, IM; Parkes, JD; Williams, R; Young, J, 1971) |
| "Pain was rated on visual analogue scales before, during, and after treatment." | 2.67 | A comparative study of diazepam and acupuncture in patients with osteoarthritis pain: a placebo controlled study. ( Eriksson, SV; Lundeberg, T; Thomas, M, 1991) |
| "Buspirone is an antianxiety compound that has been extensively evaluated in clinical trials: it has proved superior to placebo and comparable to diazepam in the treatment of patients with generalized anxiety disorder." | 2.66 | A comparison of buspirone, diazepam, and placebo in patients with chronic anxiety states. ( Lader, M; Olajide, D, 1987) |
| "Flupenthixol and diazepam were both significantly superior to placebo in reducing headaches and analgesic consumption." | 2.66 | Chronic muscle contraction headache: the importance of depression and anxiety. ( Boddie, HG; Hackett, GI; Harrison, P, 1987) |
| "Diazepam dose levels were lowest for the High group and highest for the Low group." | 2.66 | Early treatment response in anxious outpatients treated with diazepam. ( Downing, RW; Rickels, K, 1985) |
| "Recently, it has been argued that benzodiazepines may not be safe or efficacious beyond 3 months continuous dosage." | 2.65 | Comparison of the therapeutic effect, tolerance and safety of ketazolam and diazepam administered for six months to out-patients with chronic anxiety neurosis. ( Fabre, LF; McLendon, DM; Stephens, AG, 1981) |
| "CD-1 mice were dosed with Bacille Calmette-Guérin (BCG) and measures of body weight, locomotor activity, and immobility in the tail suspension test (TST) were made." | 1.39 | A depressive phenotype induced by Bacille Calmette Guérin in 'susceptible' animals: sensitivity to antidepressants. ( Clark, JA; Klee, N; Nizami, M; Platt, B; Schulenberg, J, 2013) |
| "CFA-induced mechanical allodynia resulted in increased anxiety-like behaviors as evidenced by: (1) a significant decrease in percentage of time spent and number of entries in open arms of the elevated-plus maze (EPM), (2) a decrease in number of central squares visited in the open field (OF), and (3) a reduction in active social interactions in the social interaction test (SI)." | 1.38 | Increased anxiety-like behaviors in rats experiencing chronic inflammatory pain. ( Beaudet, N; Beaudry, H; Bergeron, J; Bérubé, P; Drolet, G; Gendron, L; Parent, AJ; Sarret, P, 2012) |
| "Epilepsy affects 0." | 1.37 | Bone marrow mononuclear cells reduce seizure frequency and improve cognitive outcome in chronic epileptic rats. ( Cammarota, M; DaCosta, JC; Greggio, S; Machado, DC; Marinowic, DR; Venturin, GT; Zanirati, G, 2011) |
| "We present the case of a patient with renal cell carcinoma hospitalized for intractable cough that failed to respond adequately to usual treatments, but improved with diazepam." | 1.35 | The cough from hell: diazepam for intractable cough in a patient with renal cell carcinoma. ( Estfan, B; Walsh, D, 2008) |
| "The incidence of respiratory depression following treatment of prolonged seizures with benzodiazepines is variable in the literature." | 1.31 | Respiratory depression in the acute management of seizures. ( Dooley, JM; Harrison, R; Stewart, WA, 2002) |
| "The diazepam dose was adjusted daily to avoid oversedation." | 1.27 | High doses of diazepam improve neuroleptic-resistant chronic schizophrenic patients. ( Bloom, D; Nair, NP; Nestoros, JN; Pulman, JR; Schwartz, G, 1983) |
| " Significant relationships were found between the clinical effect and the plasma concentrations of D and DD, respectively; a curvilinear relationship resulted if the dosage was disregarded, but within the individual dosage groups the relationship was found to be linear." | 1.27 | Diazepam and desmethyldiazepam plasma concentrations in chronic anxious outpatients. ( Case, WG; Dixon, R; Downing, RW; Fridman, R; Rickels, K, 1984) |
| " The findings of modest diazepam dose and plasma concentration (mean=324 ng/ml) and of a trend toward a positive correlation between anxiety level and both dose and plasma level suggest inadequate dosage as a more likely explanation for the subjects' continued anxiety." | 1.26 | Chronic diazepam treatment in psychiatric outpatients. ( Battey, YW; Greenblatt, DJ; Laughren, TP, 1982) |
| "Early detection and treatment of drug abuse should minimize some of the difficulties involved in management of treatment-resistive patients with chronic pain." | 1.26 | Drug abuse and dependency in patients with chronic pain. ( Finlayson, RE; Maruta, T; Swanson, DW, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 65 (59.63) | 18.7374 |
| 1990's | 13 (11.93) | 18.2507 |
| 2000's | 16 (14.68) | 29.6817 |
| 2010's | 14 (12.84) | 24.3611 |
| 2020's | 1 (0.92) | 2.80 |
| Authors | Studies |
|---|---|
| Dhanani, LY | 1 |
| Totton, RR | 1 |
| Jara-Quijada, E | 1 |
| Pérez-Won, M | 1 |
| Tabilo-Munizaga, G | 1 |
| Lemus-Mondaca, R | 1 |
| González-Cavieres, L | 1 |
| Palma-Acevedo, A | 1 |
| Herrera-Lavados, C | 1 |
| Milovanovic, S | 1 |
| Grzegorczyk, A | 1 |
| Świątek, Ł | 1 |
| Grzęda, A | 1 |
| Dębczak, A | 1 |
| Tyskiewicz, K | 1 |
| Konkol, M | 1 |
| Li, Y | 3 |
| Chang, P | 1 |
| Sankaran, S | 1 |
| Jang, H | 1 |
| Nie, Y | 1 |
| Zeng, A | 1 |
| Hussain, S | 1 |
| Wu, JY | 1 |
| Chen, X | 2 |
| Shi, L | 2 |
| Senapati, A | 1 |
| Chetri, BK | 1 |
| Mitra, S | 1 |
| Shelke, RG | 1 |
| Rangan, L | 1 |
| Chauhan, AS | 1 |
| Tiwari, M | 1 |
| Indoliya, Y | 1 |
| Mishra, SK | 1 |
| Lavania, UC | 1 |
| Chauhan, PS | 1 |
| Chakrabarty, D | 1 |
| Tripathi, RD | 1 |
| Akaputra, R | 1 |
| Hatta, M | 1 |
| Massi, MN | 1 |
| Djaharuddin, I | 1 |
| Bukhari, A | 1 |
| Aminuddin, A | 1 |
| Santoso, A | 1 |
| Natzir, R | 1 |
| Bahar, B | 1 |
| Fachri, M | 1 |
| Farsida, F | 1 |
| Fathimah, A | 1 |
| Ubaidah, FM | 1 |
| Sridiana, E | 1 |
| Dwiyanti, R | 1 |
| Syukri, A | 1 |
| Junita, AR | 1 |
| Febrianti, A | 1 |
| Primaguna, MR | 1 |
| Azhar, A | 1 |
| Rajaure, YS | 1 |
| Thapa, B | 1 |
| Budhathoki, L | 1 |
| Rana, SR | 1 |
| Khadka, M | 1 |
| Batchu, UR | 1 |
| Surapaneni, JR | 1 |
| Cheemalamarri, C | 1 |
| Mandava, K | 1 |
| Puvvada, N | 1 |
| Shetty, PR | 1 |
| Mv, S | 1 |
| Ranjbarian, P | 1 |
| Goudarzi, F | 1 |
| Akya, A | 1 |
| Heidarinia, H | 1 |
| Farasat, A | 1 |
| Rostamian, M | 1 |
| Suri, K | 1 |
| Rajput, N | 1 |
| Sharma, P | 1 |
| Omble, AD | 1 |
| Kulkarni, K | 1 |
| Gahlay, GK | 1 |
| Fernandez Garcia, E | 1 |
| Paudel, U | 1 |
| Noji, MC | 1 |
| Bowman, CE | 1 |
| Rustgi, AK | 1 |
| Pitarresi, JR | 1 |
| Wellen, KE | 1 |
| Arany, Z | 1 |
| Weissenrieder, JS | 1 |
| Foskett, JK | 1 |
| Lee, MS | 1 |
| Han, HJ | 1 |
| Choi, TI | 1 |
| Lee, KH | 1 |
| Baasankhuu, A | 1 |
| Kim, HT | 1 |
| Kim, CH | 1 |
| Redd, PS | 1 |
| Payero, L | 1 |
| Gilbert, DM | 1 |
| Page, CA | 1 |
| King, R | 1 |
| McAssey, EV | 1 |
| Bodie, D | 1 |
| Diaz, S | 1 |
| Hancock, CN | 1 |
| Lee, HS | 1 |
| Jung, S | 1 |
| Lee, SW | 1 |
| Kim, YT | 1 |
| Lee, J | 1 |
| Ren, T | 1 |
| Yu, Z | 1 |
| Yu, H | 1 |
| Deng, K | 1 |
| Wang, Z | 1 |
| Li, X | 1 |
| Wang, H | 1 |
| Wang, L | 2 |
| Xu, Y | 1 |
| Lascano, J | 1 |
| Riley, L | 1 |
| Khodayari, N | 1 |
| Brantly, M | 1 |
| Gupta, R | 1 |
| Pradhan, J | 1 |
| Haldar, A | 1 |
| Murapaka, C | 1 |
| Chandra Mondal, P | 1 |
| Gao, R | 1 |
| Dai, TY | 1 |
| Meng, Z | 1 |
| Sun, XF | 1 |
| Liu, DX | 1 |
| Shi, MM | 1 |
| Li, HR | 1 |
| Kang, X | 1 |
| Bi, B | 1 |
| Zhang, YT | 1 |
| Xu, TW | 1 |
| Yan, JM | 1 |
| Jiang, Q | 1 |
| Helmchen, G | 1 |
| Guo, H | 1 |
| Xiang, W | 1 |
| Fang, Y | 1 |
| Li, J | 4 |
| Lin, Y | 2 |
| An, X | 1 |
| Jiang, D | 1 |
| Cao, Q | 1 |
| Xu, F | 1 |
| Shiigi, H | 1 |
| Wang, W | 1 |
| Chen, Z | 1 |
| Akosman, I | 1 |
| Kumar, N | 1 |
| Mortenson, R | 1 |
| Lans, A | 1 |
| De La Garza Ramos, R | 1 |
| Eleswarapu, A | 1 |
| Yassari, R | 1 |
| Fourman, MS | 1 |
| Jana, S | 1 |
| Evans, EGB | 1 |
| Jang, HS | 1 |
| Zhang, S | 2 |
| Zhang, H | 1 |
| Rajca, A | 1 |
| Gordon, SE | 1 |
| Zagotta, WN | 1 |
| Stoll, S | 1 |
| Mehl, RA | 1 |
| Miller, S | 1 |
| Lee, DA | 1 |
| Muhimpundu, S | 1 |
| Maxwell, CA | 1 |
| Liu, Z | 1 |
| Shen, F | 1 |
| Tong, Q | 1 |
| Tang, M | 1 |
| Peng, M | 1 |
| Jiao, Z | 1 |
| Jiang, Y | 1 |
| Ao, L | 1 |
| Fu, W | 1 |
| Lv, X | 1 |
| Jiang, G | 1 |
| Hou, L | 1 |
| Tu, WC | 1 |
| McManamen, AM | 1 |
| Su, X | 1 |
| Jeacopello, I | 1 |
| Takezawa, MG | 1 |
| Hieber, DL | 1 |
| Hassan, GW | 1 |
| Lee, UN | 1 |
| Anana, EV | 1 |
| Locknane, MP | 1 |
| Stephenson, MW | 1 |
| Shinkawa, VAM | 1 |
| Wald, ER | 1 |
| DeMuri, GP | 1 |
| Adams, KN | 1 |
| Berthier, E | 1 |
| Thongpang, S | 1 |
| Theberge, AB | 1 |
| Jiang, L | 1 |
| Li, Z | 1 |
| Dong, Q | 1 |
| Rong, X | 1 |
| Dong, G | 1 |
| Huang, J | 1 |
| Liang, Y | 1 |
| Sun, S | 1 |
| Zhang, R | 1 |
| Miao, Z | 1 |
| Senju, C | 1 |
| Nakazawa, Y | 1 |
| Oso, T | 1 |
| Shimada, M | 1 |
| Kato, K | 1 |
| Matsuse, M | 1 |
| Tsujimoto, M | 1 |
| Masaki, T | 1 |
| Miyazaki, Y | 1 |
| Fukushima, S | 1 |
| Tateishi, S | 1 |
| Utani, A | 1 |
| Murota, H | 1 |
| Tanaka, K | 1 |
| Mitsutake, N | 1 |
| Moriwaki, S | 1 |
| Nishigori, C | 1 |
| Ogi, T | 1 |
| Liu, C | 1 |
| Zhang, X | 1 |
| Wang, B | 1 |
| Luo, Z | 1 |
| Qian, D | 1 |
| Liu, J | 1 |
| Waterhouse, GIN | 1 |
| Barbosa, M | 1 |
| Marques-Sá, J | 1 |
| Carvalho, C | 1 |
| Fernandes, V | 1 |
| Grilli, D | 1 |
| Smetana, V | 1 |
| Ahmed, SJ | 1 |
| Shtender, V | 1 |
| Pani, M | 1 |
| Manfrinetti, P | 1 |
| Mudring, AV | 1 |
| Kuang, Y | 1 |
| Yang, D | 1 |
| Gai, S | 1 |
| He, F | 1 |
| An, B | 1 |
| Yang, P | 1 |
| Notini, L | 1 |
| Schulz, K | 1 |
| Kubeneck, LJ | 1 |
| Grigg, ARC | 1 |
| Rothwell, KA | 1 |
| Fantappiè, G | 1 |
| ThomasArrigo, LK | 1 |
| Kretzschmar, R | 1 |
| Siswanto, FM | 1 |
| Okukawa, K | 1 |
| Tamura, A | 1 |
| Oguro, A | 1 |
| Imaoka, S | 1 |
| Kim, CG | 1 |
| Jung, M | 1 |
| Kim, HS | 1 |
| Lee, CK | 1 |
| Jeung, HC | 1 |
| Koo, DH | 1 |
| Bae, WK | 1 |
| Zang, DY | 1 |
| Kim, BJ | 1 |
| Kim, H | 1 |
| Yun, UJ | 1 |
| Che, J | 1 |
| Park, S | 1 |
| Kim, TS | 1 |
| Kwon, WS | 1 |
| Park, J | 1 |
| Cho, SW | 1 |
| Nam, CM | 1 |
| Chung, HC | 1 |
| Rha, SY | 1 |
| Colombo, N | 1 |
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| Matulonis, UA | 1 |
| Oaknin, A | 1 |
| Grisham, RN | 1 |
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| Peppercorn, JM | 1 |
| Borges, VF | 1 |
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| Zanudo, JGT | 1 |
| Partridge, AH | 1 |
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| Moskowitz, A | 1 |
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| Grossestreuer, AV | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluating Specific and Non-Specific Mechanisms in Two Distinct Complementary/Integrative Interventions for Chronic Pain[NCT04744883] | Early Phase 1 | 240 participants (Anticipated) | Interventional | 2020-08-10 | Recruiting | ||
| Reduced Opioid Analgesic Requirements Via Improved Endogenous Opioid Function[NCT02469077] | 117 participants (Actual) | Interventional | 2015-08-31 | Completed | |||
| Acupuncture for Vasectomy Pre-procedural Anxiety and Pain Control in the Primary Care Setting: A Randomized Comparative Effectiveness Trial[NCT03938415] | 85 participants (Anticipated) | Interventional | 2019-06-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Mean change in 5-day electronic diary ratings of low back pain intensity from pre intervention baseline to post intervention. 9 point pain scale assessing pain intensity with 0 represents no pain and 8 represents worst possible pain. Positive values indicate reduced pain post intervention. (NCT02469077)
Timeframe: At pre-intervention baseline and again post-intervention (an expected average of 6 weeks later)
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline (pre intervention) | Change after 6 week intervention period | |
| 6 Week Aerobic Exercise Intervention | 2.75 | 0.72 |
| Normal Exercise (Control) | 2.82 | 0.18 |
Mean change in McGill Pain Questionnaire-2 total chronic back pain ratings on 3 testing days at baseline (pre intervention) and post intervention. The score ranges from 0-10 where 0 represents no pain and 10 represents most intense pain. Positive values indicate decreased back pain post intervention. (NCT02469077)
Timeframe: At pre-intervention baseline laboratory assessment and again post-intervention (an expected average of 6 weeks later)
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline (pre intervention) | Change after 6 week intervention period | |
| 6 Week Aerobic Exercise Intervention | 2.66 | 1.60 |
| Normal Exercise (Control) | 3.01 | 1.36 |
Mean change in morphine condition Drug Effects, Liking, and Take Again (DELTA) -Drug Effect subscale ratings on 3 testing days at baseline (pre intervention) and post intervention. The score ranges from 1-5 where 1 represents no effect and 5 represents very strong effect. Positive values indicate decreased overall drug effects post intervention. (NCT02469077)
Timeframe: At pre-intervention baseline and again post-intervention (an expected average of 6 weeks later)
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline (pre intervention) | Change after 6 week intervention period | |
| 6 Week Aerobic Exercise Intervention | 2.72 | 0.10 |
| Normal Exercise (Control) | 2.52 | -0.12 |
Mean change in morphine condition Drug Effects, Liking, and Take Again (DELTA) -Drug Liking subscale ratings on 3 testing days at baseline (pre intervention) and post intervention. The score ranges from 0-100 where 0 represents dislike a lot and 100 represents like a lot. Positive values indicate decreased drug liking post intervention. (NCT02469077)
Timeframe: At pre-intervention baseline and again post-intervention (an expected average of 6 weeks later)
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline (pre intervention) | Change after 6 week intervention period | |
| 6 Week Aerobic Exercise Intervention | 52.03 | 4.13 |
| Normal Exercise (Control) | 52.89 | 1.04 |
Mean change in morphine condition Drug Effects, Liking, and Take Again (DELTA) -Take Again subscale ratings on 3 testing days at baseline (pre intervention) and post intervention. The score ranges from 0-100 where 0 represents definitely would not take again and 100 represents definitely would take again. Positive values indicate decreased desire to take the drug again post intervention. (NCT02469077)
Timeframe: At pre-intervention baseline and again post-intervention (an expected average of 6 weeks later)
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline (pre intervention) | Change after 6 week intervention period | |
| 6 Week Aerobic Exercise Intervention | 54.49 | 4.40 |
| Normal Exercise (Control) | 55.04 | 1.70 |
Mean change in morphine condition VAS Opioid Effects - Unpleasantness subscale ratings on 3 testing days at baseline (pre intervention) and post intervention. The score ranges from 0-300 where 0 represents no unpleasantness and 300 represents most unpleasantness possible. Positive values indicate decreased unpleasantness post intervention. (NCT02469077)
Timeframe: At pre-intervention baseline and again post-intervention (an expected average of 6 weeks later)
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline (pre intervention) | Change after 6 week intervention period | |
| 6 Week Aerobic Exercise Intervention | 33.58 | -3.21 |
| Normal Exercise (Control) | 16.52 | 1.86 |
Mean change in morphine condition VAS Opioid Effects-Euphoria subscale ratings on 3 testing days at baseline (pre intervention) and post intervention. The score ranges from 0-300 where 0 means no euphoria and 300 means most euphoria possible. Positive values indicate decreased euphoria post intervention. (NCT02469077)
Timeframe: At pre-intervention baseline and again post-intervention (an expected average of 6 weeks later)
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline (pre intervention) | Change after 6 week intervention period | |
| 6 Week Aerobic Exercise Intervention | 100.60 | 3.19 |
| Normal Exercise (Control) | 108.24 | 0.75 |
Mean change in morphine condition VAS Opioid Effects-Sedation subscale ratings on 3 testing days at baseline (pre intervention) and post intervention. The score ranges from 0-300 where 0 means no sedation and 300 means most sedation possible. Positive values indicate decreased sedation post intervention. (NCT02469077)
Timeframe: At pre-intervention baseline and again post-intervention (an expected average of 6 weeks later)
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline (pre intervention) | Change after 6 week intervention period | |
| 6 Week Aerobic Exercise Intervention | 66.58 | 12.89 |
| Normal Exercise (Control) | 30.63 | -9.95 |
Mean change in placebo condition ratings of acute thermal pain intensity using the McGill Pain Questionnaire-Short Form on 3 testing days at baseline (per intervention) and post intervention. The score ranges from 0-33 where 0 represents no pain and 33 represents most intense pain. Positive change values indicate decreased pain responsiveness post intervention. (NCT02469077)
Timeframe: At pre-intervention baseline laboratory assessment and again post-intervention (an expected average of 6 weeks later)
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline (pre intervention) | Change after 6 week intervention period | |
| 6 Week Aerobic Exercise Intervention | 10.23 | 0.45 |
| Normal Exercise (Control) | 7.83 | -2.14 |
Mean change in Positive and Negative Affect Scale-Negative Affect subscale ratings on 3 testing days at baseline (pre intervention) and post intervention. . Scale ratings range from 10 to 50 where 10 represents lowest negative affect possible and 50 represents highest negative affect possible. Positive values indicate decreased negative affect post intervention. (NCT02469077)
Timeframe: At pre intervention baseline and again post-intervention (an expected average of 6 weeks later)
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline (pre intervention) | Change after 6 week intervention period | |
| 6 Week Aerobic Exercise Intervention | 16.38 | 0.45 |
| Normal Exercise (Control) | 15.43 | -2.14 |
"At a laboratory testing day pre and post intervention each participant received morphine sulphate (0.3mg/kg in 20ml saline vehicle initially, followed by 3 incremental doses of 0.02 mg/kg each with testing for thermal evoked pain response. Weight adjusted dosing was used by multiplying the weight of each patient in kg by 0.3mg (dose 1 only) or by .02mg (doses 2-4), with all doses infused in 20mL saline vehicle.~Mean of the change in morphine dosage required to achieve 25 % reduction in thermal evoked pain responses on testing day at baseline (pre-intervention) and post intervention. Positive values for the change in the mean between pre and post intervention indicated decreased morphine requirements post intervention." (NCT02469077)
Timeframe: At pre-intervention baseline laboratory assessment and again post-intervention (an expected average of 6 weeks later)
| Intervention | mg (Mean) | |
|---|---|---|
| Baseline (pre intervention) | Change after 6 week intervention period | |
| 6 Week Aerobic Exercise Intervention | 4.17 | -1.62 |
| Normal Exercise (Control) | 6.34 | 0.92 |
"Between-participant (aerobic exercise vs. control group) comparison of mean changes from pre- to post-intervention in opioid blockade effects for McGill Pain Questionnaire-2 Total ratings of back pain based on 3 laboratory testing days at baseline (pre intervention) and post intervention. The score ranges from 0-10 where 0 represents no pain and 10 represents most intense pain. Positive values indicate increased endogenous opioid analgesia post intervention.~This measure will test the effects of the exercise (versus control) intervention on clinical outcomes as indexed by changes in opioid blockade effects (the difference in laboratory evoked pain response evoked between placebo and naloxone drug conditions).~This is a mixed within-between subject design. Per the study protocol, the intent of outcome measures 4 and 6 was to capture opioid blockade effects (within-participant placebo-naloxone condition difference scores) at both the pre- and post-intervention lab assessments, an" (NCT02469077)
Timeframe: At pre-intervention baseline laboratory assessment and again post-intervention (an expected average of 6 weeks later)
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline (pre intervention) | Change after 6 week intervention period | |
| 6 Week Aerobic Exercise Intervention | 0.11 | -0.12 |
| Normal Exercise (Control) | 0.18 | -0.24 |
"Between-participant (aerobic exercise vs. control group) comparison of mean changes from pre- to post-intervention in opioid blockade effects for ratings of acute thermal pain intensity on the McGill Pain Questionnaire-Short Form based on 3 laboratory testing days at baseline (pre-intervention) and post intervention. The score ranges from 0-33 where 0 represents no pain and 33 represents more intense pain. Positive values indicate increased endogenous opioid analgesia post intervention.~This measure will test for endogenous opioid mechanisms of the exercise (versus control) intervention as indexed by changes in opioid blockade effects (the difference in laboratory evoked pain response evoked between placebo and naloxone drug conditions).~This is a mixed within-between subject design. Per the study protocol, the intent of outcome measures 4 and 6 was to capture opioid blockade effects (within-participant placebo-naloxone condition difference scores) at both the pre- and post-in" (NCT02469077)
Timeframe: At pre-intervention baseline laboratory assessment and again post-intervention (an expected average of 6 weeks later)
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline (pre intervention) | Change after 6 week intervention period | |
| 6 Week Aerobic Exercise Intervention | -0.33 | 1.97 |
| Normal Exercise (Control) | 0.92 | -0.61 |
4 reviews available for diazepam and Chronic Illness
| Article | Year |
|---|---|
Biofeedback for treatment of chronic idiopathic constipation in adults.
Topics: Adult; Botulinum Toxins, Type A; Chronic Disease; Constipation; Diazepam; Feedback, Physiological; H | 2014 |
A primer of ethical issues involving opioid therapy for chronic nonmalignant pain in a multidisciplinary setting.
Topics: Analgesics, Opioid; Chickenpox; Cholecystectomy; Chronic Disease; Diazepam; Facial Pain; Female; Her | 2009 |
The blood-brain barrier in acute and chronic hypertension.
Topics: Acute Disease; Amphetamine; Animals; Barbiturates; Blood Pressure; Blood-Brain Barrier; Cell Membran | 1980 |
Baclofen: a preliminary report of its pharmacological properties and therapeutic efficacy in spasticity.
Topics: Adolescent; Adult; Aminobutyrates; Animals; Chlorobenzenes; Chronic Disease; Clinical Trials as Topi | 1974 |
24 trials available for diazepam and Chronic Illness
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Acute Kidney Injury; Adult; Aged; Albumins; Alloys; Amides; Amino Acids; Animals; Antineoplastic Com | 2023 |
Comparison of the therapeutic effect, tolerance and safety of ketazolam and diazepam administered for six months to out-patients with chronic anxiety neurosis.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; B | 1981 |
Long-term diazepam therapy and clinical outcome.
Topics: Adult; Anxiety Disorders; Chronic Disease; Clinical Trials as Topic; Diazepam; Double-Blind Method; | 1983 |
Diazepam in the treatment of dyspnoea in the 'Pink Puffer' syndrome.
Topics: Aged; Airway Obstruction; Carbon Dioxide; Chronic Disease; Depression; Diazepam; Dyspnea; Humans; Ma | 1980 |
Persistence of chronic mood disorders: a 2 year follow-up.
Topics: Adult; Antidepressive Agents; Chronic Disease; Cohort Studies; Combined Modality Therapy; Diazepam; | 1995 |
Exposure in vivo of agoraphobics: contributions of diazepam, group exposure, and anxiety evocation.
Topics: Administration, Oral; Agoraphobia; Anxiety; Behavior Therapy; Chronic Disease; Desensitization, Psyc | 1976 |
Effects on EMG feedback, diazepam and their combination on chronic anxiety.
Topics: Adult; Anxiety; Biofeedback, Psychology; Chronic Disease; Diazepam; Electromyography; Evaluation Stu | 1977 |
Interaction of diazepam and naloxone on acupuncture induced pain relief.
Topics: Acupuncture Analgesia; Aged; Animals; Chronic Disease; Combined Modality Therapy; Diazepam; Electroa | 1991 |
Interaction of diazepam and naloxone on acupuncture induced pain relief.
Topics: Acupuncture Analgesia; Aged; Animals; Chronic Disease; Combined Modality Therapy; Diazepam; Electroa | 1991 |
Interaction of diazepam and naloxone on acupuncture induced pain relief.
Topics: Acupuncture Analgesia; Aged; Animals; Chronic Disease; Combined Modality Therapy; Diazepam; Electroa | 1991 |
Interaction of diazepam and naloxone on acupuncture induced pain relief.
Topics: Acupuncture Analgesia; Aged; Animals; Chronic Disease; Combined Modality Therapy; Diazepam; Electroa | 1991 |
A comparative study of diazepam and acupuncture in patients with osteoarthritis pain: a placebo controlled study.
Topics: Acupuncture Analgesia; Adult; Cervical Vertebrae; Chronic Disease; Diazepam; Humans; Middle Aged; Os | 1991 |
Etizolam versus placebo in the treatment of panic disorder with agoraphobia: a double-blind study.
Topics: Adult; Agoraphobia; Chronic Disease; Diazepam; Double-Blind Method; Drug Administration Schedule; Fe | 1990 |
A comparison of buspirone, diazepam, and placebo in patients with chronic anxiety states.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Buspirone; Chronic Disease; Clinical Trials as Topic; | 1987 |
Chronic muscle contraction headache: the importance of depression and anxiety.
Topics: Adolescent; Adult; Anxiety; Chronic Disease; Clinical Trials as Topic; Depression; Diazepam; Double- | 1987 |
Repetitive intravenous dihydroergotamine as therapy for intractable migraine.
Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Diazepam; Dihydroergotamine; Female; Humans; | 1986 |
Indications and contraindications for chronic anxiolytic treatment: is there tolerance to the anxiolytic effect?
Topics: Anxiety; Chronic Disease; Clinical Trials as Topic; Clorazepate Dipotassium; Diazepam; Double-Blind | 1985 |
Early treatment response in anxious outpatients treated with diazepam.
Topics: Adult; Ambulatory Care; Anxiety Disorders; Chronic Disease; Clinical Trials as Topic; Diazepam; Fema | 1985 |
Baclofen: a preliminary report of its pharmacological properties and therapeutic efficacy in spasticity.
Topics: Adolescent; Adult; Aminobutyrates; Animals; Chlorobenzenes; Chronic Disease; Clinical Trials as Topi | 1974 |
Sedative effects on physiological and psychological measures in anxious patients.
Topics: Amobarbital; Anti-Anxiety Agents; Anxiety; Auditory Perception; Chlordiazepoxide; Chronic Disease; C | 1974 |
Clinical comparison of anxiolytic drug therapy.
Topics: Administration, Oral; Adolescent; Adult; Amobarbital; Anti-Anxiety Agents; Anxiety; Barbiturates; Ca | 1974 |
Clorazepate dipotassium, diazepam and placebo in chronic anxiety.
Topics: Adolescent; Adult; Aged; Anxiety Disorders; Benzazepines; Blood Pressure; Carboxylic Acids; Chronic | 1973 |
Enhanced relief of phobias by flooding during waning diazepam effect.
Topics: Adolescent; Adult; Attitude; Behavior Therapy; Chronic Disease; Clinical Trials as Topic; Diazepam; | 1972 |
Drugs and group psychotherapy in neurotic depression.
Topics: Adult; Chronic Disease; Clinical Trials as Topic; Depression; Diazepam; Drug Evaluation; Female; Hum | 1974 |
A double-blind crossover comparison between clothiapine and diazepam in the treatment of mental symptoms in chronic alcoholics.
Topics: Adult; Alcoholism; Analysis of Variance; Chronic Disease; Clinical Trials as Topic; Diazepam; Dibenz | 1974 |
Treatment of chronic hallucinations with diazepam and phenothiazines.
Topics: Adult; Auditory Perception; Chlorpromazine; Chronic Disease; Clinical Trials as Topic; Diazepam; Fem | 1967 |
The psychological effects of propranolol in the abstinence phase of chronic alcoholics.
Topics: Adult; Alcoholism; Anxiety; Chlormethiazole; Chronic Disease; Clinical Trials as Topic; Diazepam; Hu | 1971 |
82 other studies available for diazepam and Chronic Illness
| Article | Year |
|---|---|
Increasing efficacy and reducing side effects in treatment of chronic anal fissures: A study of topical diazepam therapy.
Topics: Administration, Topical; Analgesics; Chronic Disease; Diazepam; Dose-Response Relationship, Drug; Dr | 2017 |
Residual avoidance: A new, consistent and repeatable readout of chronic stress-induced conflict anxiety reversible by antidepressant treatment.
Topics: Animals; Antidepressive Agents; Anxiety; Avoidance Learning; Chronic Disease; Depression; Diazepam; | 2019 |
Chronic mild stress-induced changes of risk assessment behaviors in mice are prevented by chronic treatment with fluoxetine but not diazepam.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Chronic Disease; Corticosterone; Diazepam; Fluoxetin | 2014 |
Cys34-cysteinylated human serum albumin is a sensitive plasma marker in oxidative stress-related chronic diseases.
Topics: Aged; Amino Acids, Branched-Chain; Bilirubin; Biomarkers; Chronic Disease; Cysteine; Diabetes Mellit | 2014 |
Effects of chronic mild stress on the development of drug dependence in rats.
Topics: Animals; Chronic Disease; Citalopram; Depressive Disorder; Diazepam; Disease Models, Animal; Flumaze | 2014 |
[Effects of diazepam on mixed anxiety/depression state in male mice].
Topics: Animals; Anti-Anxiety Agents; Anxiety; Chronic Disease; Depression; Diazepam; Male; Mice; Stress, Ps | 2013 |
High-Speed imaging reveals opposing effects of chronic stress and antidepressants on neuronal activity propagation through the hippocampal trisynaptic circuit.
Topics: Animals; Antidepressive Agents; Azepines; Benzamides; Brain-Derived Neurotrophic Factor; Central Ner | 2015 |
Exogenous daytime melatonin modulates response of adolescent mice in a repeated unpredictable stress paradigm.
Topics: Age Factors; Animals; Anti-Anxiety Agents; Antioxidants; Behavior, Animal; Biomarkers; Brain; Chroni | 2017 |
Evaluation of the repeated open-space swim model of depression in the mouse.
Topics: Adaptation, Psychological; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; | 2008 |
A case report of chronic tetanus.
Topics: Adult; Anti-Infective Agents; Anticonvulsants; Chlorpromazine; Chronic Disease; Diagnosis, Different | 2008 |
Behavioral effects of acute and chronic oral administration of barakol in rats.
Topics: Acute Disease; Administration, Oral; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Benzop | 2009 |
Social separation and diazepam withdrawal increase anxiety in the elevated plus-maze and serotonin turnover in the median raphe and hippocampus.
Topics: Acute Disease; Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Chronic Disease; Diazepam; | 2010 |
Effect of phosphamidon on convulsive behavior and biochemical parameters: modulation by progesterone and 4'-chlorodiazepam in rats.
Topics: Acetylcholinesterase; Acute Disease; Animals; Antioxidants; Behavior, Animal; Brain; Chronic Disease | 2010 |
Bone marrow mononuclear cells reduce seizure frequency and improve cognitive outcome in chronic epileptic rats.
Topics: Animals; Bone Marrow Cells; Cell Transplantation; Chronic Disease; Cognition Disorders; Diazepam; Di | 2011 |
Increased anxiety-like behaviors in rats experiencing chronic inflammatory pain.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Chronic Disease; Dark Adaptation; Diaze | 2012 |
A depressive phenotype induced by Bacille Calmette Guérin in 'susceptible' animals: sensitivity to antidepressants.
Topics: Animals; Antidepressive Agents; BCG Vaccine; Chronic Disease; Depression; Desipramine; Diazepam; Dis | 2013 |
Respiratory depression in the acute management of seizures.
Topics: Anticonvulsants; Child; Child, Preschool; Chronic Disease; Diazepam; Drug Therapy, Combination; Huma | 2002 |
[Effects of diazepam on intracardiac hemodynamics in patients with chronic cardiac failure].
Topics: Anticonvulsants; Chronic Disease; Diazepam; Female; Heart Failure; Heart Rate; Hemodynamics; Humans; | 2003 |
Use of a new benzodiazepine derivative (valium) in chronically ill and disturbed elderly patients.
Topics: Aged; Aged, 80 and over; Benzodiazepines; Chronic Disease; Diazepam; Geriatrics; Humans; Mental Diso | 1962 |
Pharmacological characterisation of acid-induced muscle allodynia in rats.
Topics: Acids; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ataxia; Carbazoles; Chr | 2004 |
Sex differences in effects of mild chronic stress on seizure risk and GABAA receptors in rats.
Topics: Animals; Chlorides; Chronic Disease; Corticosterone; Diazepam; Ethanol; Female; Male; Rats; Rats, Sp | 2004 |
[Combined therapy for the chronic pelvic pain syndrome].
Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Anti-Bacterial Agents; Chronic Disease; Diazepam; D | 2004 |
Chronic pain induces anxiety with concomitant changes in opioidergic function in the amygdala.
Topics: Amygdala; Analgesics, Opioid; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Benzamides; | 2006 |
Reversal of pathological pain through specific spinal GABAA receptor subtypes.
Topics: Analgesics; Animals; Brain; Capsaicin; Chronic Disease; Diazepam; Disease Models, Animal; Fluorobenz | 2008 |
TMD chronic pain and masseter silent period in psychiatric patients on antidepressive therapy.
Topics: Adult; Analysis of Variance; Anti-Anxiety Agents; Antidepressive Agents; Case-Control Studies; Chron | 2008 |
Evaluation of behavioural and antioxidant activity of Cytisus scoparius Link in rats exposed to chronic unpredictable mild stress.
Topics: Animals; Antioxidants; Behavior, Animal; Catalase; Chronic Disease; Cytisus; Diazepam; Dose-Response | 2008 |
The cough from hell: diazepam for intractable cough in a patient with renal cell carcinoma.
Topics: Adult; Anticonvulsants; Carcinoma, Renal Cell; Chronic Disease; Cough; Diazepam; Female; Humans; Kid | 2008 |
High doses of diazepam improve neuroleptic-resistant chronic schizophrenic patients.
Topics: Adult; Antipsychotic Agents; Chronic Disease; Diazepam; Drug Resistance; Female; Humans; Male; Middl | 1983 |
Withdrawal after substitution of a short-acting for a long-acting benzodiazepine.
Topics: Anti-Anxiety Agents; Anxiety; Chronic Disease; Delayed-Action Preparations; Diazepam; Flurazepam; Ha | 1983 |
Long-term benzodiazepine therapy: benefits and risks.
Topics: Adult; Aged; Anti-Anxiety Agents; Anxiety; Chronic Disease; Diazepam; Female; Follow-Up Studies; Hum | 1984 |
Diazepam and desmethyldiazepam plasma concentrations in chronic anxious outpatients.
Topics: Adult; Anxiety Disorders; Chronic Disease; Diazepam; Female; Humans; Male; Middle Aged; Nordazepam | 1984 |
Review of results of four regimens for treatment of chronic non-bacterial prostatitis.
Topics: Adult; Anti-Infective Agents, Urinary; Chronic Disease; Diazepam; Drug Combinations; Humans; Leukocy | 1983 |
Chronic diazepam treatment in psychiatric outpatients.
Topics: Adult; Aged; Ambulatory Care; Anxiety Disorders; Chronic Disease; Diazepam; Humans; Male; Middle Age | 1982 |
Experimental chronic epilepsy in rats: a screening method for antiepileptic drugs.
Topics: Animals; Anticonvulsants; Chlorides; Chronic Disease; Clonazepam; Diazepam; Disease Models, Animal; | 1983 |
An improved technique for alcohol neurolysis of the celiac plexus.
Topics: Abdominal Neoplasms; Anesthesia, Local; Celiac Plexus; Chronic Disease; Crohn Disease; Denervation; | 1982 |
A controlled trial of diazepam withdrawal in chronically anxious outpatients.
Topics: Adult; Aged; Anxiety Disorders; Chronic Disease; Diazepam; Dose-Response Relationship, Drug; Humans; | 1982 |
Clinical effects and metabolism of diazepam in patients with chronic liver disease.
Topics: Adult; Behavior; Chronic Disease; Diazepam; Humans; Liver Cirrhosis; Liver Diseases; Middle Aged; Ps | 1982 |
Pemphigus vulgaris: anaesthesia in the traumatised patient.
Topics: Adult; Anesthesia, General; Anesthesia, Intravenous; Chronic Disease; Diazepam; Female; Humans; Keta | 1982 |
[The effect of diazepam on the activity of carboxypeptidase N and the angiotensin-converting enzyme in sections of the brain of rats with differing normal emotionality and in emotional stress].
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Brain; Brain Chemistry; Chronic Disease; Diazepa | 1994 |
Complications resulting from the use of Chinese herbal medications containing undeclared prescription drugs.
Topics: Adult; Aged; Arthritis; Chronic Disease; Depression; Diazepam; Drugs, Chinese Herbal; Female; Gastro | 1995 |
Altered responses to medications exposed to excessive temperatures during shipping.
Topics: Chronic Disease; Diazepam; Drug Stability; Drug Storage; Female; Hot Temperature; Humans; Meperidine | 1995 |
[The lidocaine test in tinnitus. Determination of its current status].
Topics: Administration, Oral; Adult; Aged; Auditory Threshold; Chronic Disease; Diazepam; Dose-Response Rela | 1994 |
Chronic pain-related behaviors in spinally injured rats: evidence for functional alterations of the endogenous cholecystokinin and opioid systems.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Cholecystokinin; Chronic Disease; Diazepam; Endorphi | 1994 |
Benzodiazepine receptor distribution and diazepam binding in schizophrenia: an exploratory study.
Topics: Adult; Benzodiazepines; Binding Sites; Chronic Disease; Diazepam; Flumazenil; Frontal Lobe; Growth H | 1997 |
[Chronic pelvic pains].
Topics: Adult; Affective Disorders, Psychotic; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Com | 1996 |
Blockade of spreading depression in chronic epileptic rats: reversion by diazepam.
Topics: Animals; Anticonvulsants; Chronic Disease; Cortical Spreading Depression; Diazepam; Electroencephalo | 1997 |
Plasma and CSF benzodiazepine receptor ligand concentrations in cirrhotic patients with hepatic encephalopathy: relationship to severity of encephalopathy and to pharmaceutical benzodiazepine intake.
Topics: Animals; Benzodiazepines; Binding, Competitive; Cell Fractionation; Cerebellum; Chronic Disease; Clo | 1998 |
Radial entrapment neuropathy due to chronic injection-induced triceps fibrosis.
Topics: Adult; Chronic Disease; Diazepam; Dimenhydrinate; Diphenhydramine; Drug Therapy, Combination; Electr | 2001 |
Diminished allopregnanolone enhancement of GABA(A) receptor currents in a rat model of chronic temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Chronic Disease; Diazepam; Electric Conductivity; Epilepsy, Temporal Lobe; | 2001 |
Treatment plan for acute and chronic adrenergic poisoning crisis utilizing sympatholytic effects of the B1-B2 receptor site blocker propranolol (Inderal) in concert with diazepam and urine acidification.
Topics: Acute Disease; Central Nervous System Stimulants; Chronic Disease; Diazepam; Drug Therapy, Combinati | 1979 |
The use of psychoactive drugs in the long-term treatment of chronic alcoholics.
Topics: Alcoholism; Anti-Anxiety Agents; Antipsychotic Agents; Anxiety; Chlordiazepoxide; Chlorpromazine; Ch | 1975 |
[What is certain in the therapy of porphyrias?].
Topics: Acute Disease; Aspirin; Barbiturates; Chloramphenicol; Chronic Disease; Diazepam; Humans; Porphyrias | 1977 |
Drug abuse and dependency in patients with chronic pain.
Topics: Age Factors; Chronic Disease; Codeine; Dextropropoxyphene; Diazepam; Female; Humans; Intelligence; M | 1979 |
[Problem of focal pathology in "genuine" epilepsy].
Topics: Animals; Chronic Disease; Cortical Synchronization; Diazepam; Electroencephalography; Evoked Potenti | 1979 |
[Specific features of sodium oxybutyrate and seduxen action on the indices of cerebral circulation in cerebrovascular insufficiency].
Topics: Cerebrovascular Circulation; Chronic Disease; Diazepam; Humans; Hydroxybutyrates; Intracranial Arter | 1977 |
Plasma protein binding of diazepam and tolbutamide in chronic alcoholics.
Topics: Alcoholism; Blood Proteins; Chemical and Drug Induced Liver Injury; Chronic Disease; Diazepam; Femal | 1976 |
Intravenous administration of diazepam in patients with chronic liver disease.
Topics: Chronic Disease; Diazepam; Dose-Response Relationship, Drug; Electroencephalography; Humans; Injecti | 1976 |
Effect on respiration of diazepam, chloropromazine and haloperidol in patients with chronic airways obstruction.
Topics: Aged; Carbon Dioxide; Chlorpromazine; Chronic Disease; Depression, Chemical; Diazepam; Haloperidol; | 1976 |
Reduced concentrations of plasma diazepam in chronic alcoholic patients following an oral administration of diazepam.
Topics: Administration, Oral; Adult; Alcoholism; Chromatography, Gas; Chronic Disease; Diazepam; Female; Hum | 1975 |
Possible enhancing effects of diazepam with reserpine in a chronic schizophrenic patient with tardive dyskinesia.
Topics: Adult; Antipsychotic Agents; Chronic Disease; Diazepam; Drug Therapy, Combination; Dyskinesia, Drug- | 1989 |
[Evaluation of the types of anesthesia for labor in parturients with chronic fetal hypoxia].
Topics: Adult; Anesthesia, Obstetrical; Apgar Score; Chronic Disease; Diazepam; Electronarcosis; Evaluation | 1986 |
[A case of chronic hyperventilation syndrome effectively treated by metoprolol].
Topics: Adult; Chronic Disease; Diazepam; Drug Therapy, Combination; Female; Humans; Hyperventilation; Metop | 1988 |
[A case of chronic and cephalic tetanus].
Topics: Adult; Chronic Disease; Cranial Nerve Diseases; Diazepam; Female; Humans; Prednisolone; Tetanus | 1987 |
Assessment and management of chronic pain.
Topics: Analgesics; Anticonvulsants; Antidepressive Agents; Chronic Disease; Diazepam; Hospital Units; Human | 1986 |
Priapism during regular haemodialysis.
Topics: Adult; Chronic Disease; Diazepam; Glomerulonephritis; Heparin; Home Care Services; Humans; Infusions | 1974 |
Drug induced dystonia tarda: treatment with L-dopa.
Topics: Antipsychotic Agents; Chlorpromazine; Chronic Disease; Diazepam; Dihydroxyphenylalanine; Dystonia Mu | 1973 |
[Diazepam in chronic epilepsy].
Topics: Chronic Disease; Diazepam; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged | 1967 |
Rheumatology.
Topics: Acute Disease; Aged; Analgesics; Arthritis, Rheumatoid; Chronic Disease; Diazepam; Female; Gout; Hum | 1972 |
The evaluation of hemoptysis with fiberoptic bronchoscopy.
Topics: Acute Disease; Adult; Bronchiectasis; Bronchitis; Bronchoscopy; Chronic Disease; Diazepam; Female; F | 1973 |
Accidental ingestion of water hemlock. Report of two patients with acute and chronic effects.
Topics: Acute Disease; Adolescent; California; Chronic Disease; Diazepam; Humans; Male; Neurologic Manifesta | 1973 |
The lazy respiratory center--or how to recognize a tired horse. Clinical conference in pulmonary disease from Northwestern University-McGaw Medical Center, Chicago.
Topics: Brain Diseases; Chemoreceptor Cells; Chronic Disease; Diagnosis, Differential; Diazepam; Digoxin; Fu | 1974 |
Treatment of uncontrolled seizure activity with diazepam.
Topics: Acute Disease; Adolescent; Adult; Aged; Anticonvulsants; Brain Diseases; Child; Chronic Disease; Com | 1968 |
Suspected neurotoxicity from intravenous penicillin: a patient case.
Topics: Acute Kidney Injury; Ampicillin; Blood Urea Nitrogen; Chronic Disease; Creatine; Diazepam; Gentamici | 1972 |
Treatment of anxiety.
Topics: Adolescent; Adult; Anxiety; Anxiety Disorders; Behavior Therapy; Chlorpromazine; Chronic Disease; Di | 1972 |
Clinical and electroencephalographic assessment of diazepam in liver disease.
Topics: Alcoholism; Budd-Chiari Syndrome; Cholestasis; Chronic Disease; Consciousness; Diazepam; Electroence | 1971 |
Effects of hypertension by means of socio-psycho-somatic relief at 'Kuren'.
Topics: Balneology; Chronic Disease; Diazepam; Health Resorts; Humans; Hypertension; Middle Aged; Milieu The | 1971 |
Restless legs syndrome in chronic pulmonary disease.
Topics: Aged; Bronchitis; Chronic Disease; Diazepam; Humans; Leg; Lung Diseases; Male; Middle Aged; Paresthe | 1970 |
[Neuropsychotropic drugs in the treatment of so-called pain syndromes].
Topics: Aminobutyrates; Benperidol; Chronic Disease; Diazepam; Humans; Hydantoins; Neuralgia; Pain; Procaina | 1970 |
Organic psychosis.
Topics: Acute Disease; Affective Symptoms; Bender-Gestalt Test; Chlordiazepoxide; Chlorpromazine; Chronic Di | 1968 |
The treatment of recurrent convulsions with intravenous injection of diazepam.
Topics: Adolescent; Adult; Aged; Child; Chronic Disease; Diazepam; Epilepsy; Female; Humans; Injections, Int | 1968 |
[Histological findings in animals exposed to acute and chronic intoxication with methyldiazepinone].
Topics: Acute Disease; Animals; Chronic Disease; Diazepam; Kidney; Liver; Rabbits | 1969 |
[Management of chronic schizophrenias using Valium].
Topics: Aged; Catatonia; Chronic Disease; Diazepam; Drug Synergism; Female; Humans; Paranoid Disorders; Schi | 1969 |