diazepam and Cholera Infantum studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Research Excerpts

Excerpt	Relevance	Reference
"Thirty-four anxious patients with gastrointestinal disorders were studied in order to evaluate the effectiveness of a new 1,5-benzodiazepine antianxiety agent (HR 376)."	2.64	Effect of a new benzodiazepine derivate, clobazam, in anxious patients with gastrointestinal disorders. ( Aparicio, N; Laudano, O; Lujan, L; Moizeszowicz, J; Peralta, M, 1977)
" We designed a study to evaluate the efficacy and adverse effects of diazepam and meperidine in combination for sedation in ambulatory pediatric patients undergoing endoscopy, colonoscopy, or liver biopsy."	1.28	Efficacy and safety of a diazepam and meperidine combination for pediatric gastrointestinal procedures. ( Li, BU; Lininger, B; McClung, HJ; Murray, RD; Nahata, MC; Zingarelli, J, 1990)
"To minimize the occurrence of hypoxemia during gastroscopy, narcotics should probably not be used in the premedication of elderly patients."	1.26	Arterial oxygen tension changes in elderly patients undergoing upper gastrointestinal endoscopy. I. Possible causes. ( Gilat, T; Laniado, S; Oppenheim, D; Ratan, J; Rozen, P, 1979)

Timeframe	Studies, this research(%)	All Research%
pre-1990	35 (87.50)	18.7374
1990's	4 (10.00)	18.2507
2000's	1 (2.50)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
Lee, DW	1
Chan, AC	1
Sze, TS	1
Ko, CW	1
Poon, CM	1
Chan, KC	1
Sin, KS	1
Chung, SC	1
VOEGTLIN, WL	1
Thompson, DG	1
Lennard-Jones, JE	2
Evans, SJ	1
Cowan, RE	1
Murray, RS	1
Wright, JT	1
Webberley, MJ	1
Cuschieri, A	1
Jones, R	1
Shemesh, E	1
Bat, L	1
Yahav, J	1
Niv, Y	1
Jonas, A	1
Rozen, P	2
Baume, P	1
Tracey, M	1
Dawson, L	1
Luyckx, A	1
Van Cauwenberge, H	1
Laudano, O	2
Peralta, M	1
Lujan, L	1
Aparicio, N	1
Moizeszowicz, J	1
Cook, PJ	1
Bennett, PN	1
Warnes, TW	1
Stoianov, E	1
Koeva, T	1
Danev, S	1
Goranova, M	1
Kunovski, M	1
Oppenheim, D	1
Ratan, J	1
Laniado, S	1
Gilat, T	1
Mehta, D	1
Mehta, S	1
Mathew, P	1
Vezzadini, P	1
Giorgi-Conciato, M	2
Tomassetti, P	1
Finatti, F	1
Re, C	1
Schiller, KF	1
Tedesco, FJ	1
Goldstein, PD	1
Gleason, WA	1
Keating, JP	1
Donelly, M	1
Scott, WA	1
Daly, DS	1
Noyes, R	1
Cook, B	1
Garvey, M	1
Summers, R	1
Scholer, SG	1
Schafer, DF	1
Potter, JF	1
Nahata, MC	1
Murray, RD	1
Zingarelli, J	1
Li, BU	1
McClung, HJ	1
Lininger, B	1
Scuto, S	1
Del Rossi, C	1
Beseghi, U	1
Violini, A	1
Mori, M	1
Gelmetti, M	1
Rollo, S	1
Chinelli, C	1
Kuzin, MI	1
Shatalov, VN	1
Avrutskiĭ, MIa	1
Shloznikov, BM	1
Machulin, AV	1
Stermer, E	1
Levy, H	1
Gerstel, R	1
Cantor, DS	1
Baldridge, ET	1
Filip, V	1
Sladká, R	1
Jarosová, M	1
Libingerová, E	1
Bacíková, R	1
Tůma, I	1
Novotný, J	1
Haskovcová, V	1
Faltus, F	1
Karen, P	1
Kasich, AM	1
Newbold, HL	1
Mosher, LR	1
Berci, G	1
Morgenstern, L	1
Panish, J	1
Shore, JM	1
Mirelli, E	2
Fichera, G	2
Bordas Alsina, DJ	1
De Martino, G	1
Gaudieri, V	1
Caruso, D	1
De Iorio, A	1
Hofmann, KW	1
Manach, J	1
Sögtrop, HH	1
Deutsch, EM	1
Witzel, K	1
Malaguti, P	1
Chiti, E	1
Fischer, M	1

Trial	Enrollment	Study Type	Start Date	Status
[NCT00848861]	92 participants (Actual)	Interventional	2006-02-28	Completed
Comparison of Ketamine-propofol Sedation Protocols With Fentanyl-propofol Administered by Endoscopist or Anesthesiologist at Colonoscopy[NCT03607110]	120 participants (Actual)	Observational	2018-03-01	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
[Biological and clinical aspects of the participation of neuropeptides in the mechanisms of electroanesthesia]. Vestnik Akademii meditsinskikh nauk SSSR, 1987, Issue:2 Topics: Adult; Animals; beta-Endorphin; Diazepam; Electroencephalography; Electronarcosis; Endorphins; Evoke	1987
[Dipotassium chlorazepate. Clinical reports on a new anxiolytic]. Arzneimittel-Forschung, 1970, Volume: 20, Issue:1 Topics: Adult; Aged; Alcoholism; Automobile Driving; Cardiovascular Diseases; Diabetes Mellitus; Diazepam; D	1970

Article	Year
Patient-controlled sedation versus intravenous sedation for colonoscopy in elderly patients: a prospective randomized controlled trial. Gastrointestinal endoscopy, 2002, Volume: 56, Issue:5 Topics: Aged; Alfentanil; Analgesia, Patient-Controlled; Anesthetics, Intravenous; Colonoscopy; Conscious Se	2002
Patient-controlled sedation versus intravenous sedation for colonoscopy in elderly patients: a prospective randomized controlled trial. Gastrointestinal endoscopy, 2002, Volume: 56, Issue:5 Topics: Aged; Alfentanil; Analgesia, Patient-Controlled; Anesthetics, Intravenous; Colonoscopy; Conscious Se	2002
Patient-controlled sedation versus intravenous sedation for colonoscopy in elderly patients: a prospective randomized controlled trial. Gastrointestinal endoscopy, 2002, Volume: 56, Issue:5 Topics: Aged; Alfentanil; Analgesia, Patient-Controlled; Anesthetics, Intravenous; Colonoscopy; Conscious Se	2002
Patient-controlled sedation versus intravenous sedation for colonoscopy in elderly patients: a prospective randomized controlled trial. Gastrointestinal endoscopy, 2002, Volume: 56, Issue:5 Topics: Aged; Alfentanil; Analgesia, Patient-Controlled; Anesthetics, Intravenous; Colonoscopy; Conscious Se	2002
Patients appreciate premedication for endoscopy. Lancet (London, England), 1980, Aug-30, Volume: 2, Issue:8192 Topics: Barium Sulfate; Diazepam; Endoscopes; Endoscopy; Female; Gastrointestinal Diseases; Humans; Male; Pr	1980
Efficacy of two minor tranquilizers in relieveing symptoms of functional gastrointestinal distress. Australian and New Zealand journal of medicine, 1975, Volume: 5, Issue:6 Topics: Adult; Aerophagy; Aged; Anti-Anxiety Agents; Clinical Trials as Topic; Diazepam; Female; Gastrointes	1975
Effect of a new benzodiazepine derivate, clobazam, in anxious patients with gastrointestinal disorders. Journal of clinical pharmacology, 1977, Volume: 17, Issue:7 Topics: Adult; Anti-Anxiety Agents; Anxiety; Clinical Trials as Topic; Diazepam; Female; Gastrointestinal Di	1977
Pre-medication for endoscopy. A trial of atropine, pentazocine or pethidine as a supplement to diazepam. Scandinavian journal of gastroenterology, 1978, Volume: 13, Issue:1 Topics: Adult; Aged; Atropine; Clinical Trials as Topic; Diazepam; Double-Blind Method; Drug Evaluation; End	1978
[Clinical study of combined anesthesia with ketamine and diazepam]. Khirurgiia, 1978, Volume: 31, Issue:6 Topics: Adolescent; Adult; Aged; Analgesia; Anesthesia, Intravenous; Blood Pressure; Clinical Trials as Topi	1978
[Clinical study of gefarnate-diazepam combination]. La Clinica terapeutica, 1975, Apr-30, Volume: 73, Issue:2 Topics: Clinical Trials as Topic; Diazepam; Drug Combinations; Drug Evaluation; Fatty Acids, Unsaturated; Ga	1975
A comparison of sedation for upper GI endoscopy using diazepam with demerol or midazolam with alfentanil. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:4 Pt 2 Topics: Alfentanil; Anesthesia, General; Arousal; Diazepam; Endoscopy; Female; Gastrointestinal Diseases; Hu	1990
[Midazolam as premedication for upper gastrointestinal endoscopy]. Harefuah, 1987, Jan-01, Volume: 112, Issue:1 Topics: Clinical Trials as Topic; Diazepam; Double-Blind Method; Endoscopy; Gastrointestinal Diseases; Human	1987
Chlorazepate dipotassium in the treatment of anxiety associated with chronic gastrointestinal disease. Current therapeutic research, clinical and experimental, 1973, Volume: 15, Issue:3 Topics: Adult; Aged; Anxiety; Benzazepines; Clinical Trials as Topic; Diazepam; Female; Gastrointestinal Dis	1973
Relief of anxiety and related emotions in patients with gastrointestinal disorders. A double-blind controlled study. The American journal of digestive diseases, 1971, Volume: 16, Issue:12 Topics: Adult; Aged; Anxiety; Body Weight; Clinical Trials as Topic; Diazepam; Evaluation Studies as Topic;	1971

diazepam and Cholera Infantum

Research Excerpts

Research

Studies (40)

Authors

Clinical Trials (2)

Trial Overview

Reviews

Trials

Other Studies

Article	Year
MANAGEMENT OF FUNCTIONAL GASTROINTESTINAL DISORDERS WITH DIAZEPAM. Applied therapeutics, 1964, Volume: 6 Topics: Biomedical Research; Chlordiazepoxide; Diazepam; Disease Management; Gastrointestinal Diseases; Geri	1964
Response of patients to upper gastrointestinal endoscopy: effect of inherent personality traits and premedication with diazepam. British medical journal (Clinical research ed.), 1982, Jul-24, Volume: 285, Issue:6337 Topics: Adolescent; Adult; Aged; Diazepam; Endoscopy; Female; Gastrointestinal Diseases; Humans; Male; Memor	1982
Response of patients to upper gastrointestinal endoscopy: effect of inherent personality traits and premedication with diazepam. British medical journal (Clinical research ed.), 1982, Aug-14, Volume: 285, Issue:6340 Topics: Diazepam; Endoscopy; Gastrointestinal Diseases; Humans; Personality; Premedication	1982
Ketamine anesthesia for pediatric gastrointestinal procedures. Israel journal of medical sciences, 1982, Volume: 18, Issue:7 Topics: Adolescent; Anesthesia, General; Atropine; Child; Child, Preschool; Diazepam; Endoscopy; Gastrointes	1982
[Therapeutic news of 1975]. Revue medicale de Liege, 1976, Apr-15, Volume: 31, Issue:8 Topics: Bismuth; Cardiovascular Diseases; Diazepam; Drug Therapy; Endocrine System Diseases; Gastrointestina	1976
Clinical study of clobazam in patients with gastrointestinal disorders [proceedings]. British journal of clinical pharmacology, 1979, Volume: 7 Suppl 1 Topics: Anti-Anxiety Agents; Anxiety; Diazepam; Double-Blind Method; Female; Gastrointestinal Diseases; Huma	1979
Arterial oxygen tension changes in elderly patients undergoing upper gastrointestinal endoscopy. I. Possible causes. Scandinavian journal of gastroenterology, 1979, Volume: 14, Issue:5 Topics: Aged; Atropine; Diazepam; Female; Gastrointestinal Diseases; Gastroscopy; Humans; Hypoxia; Injection	1979
Unusual abdominal complications of a suicidal overdose of analgesic and psychotropic drugs in an elderly patient. Journal of the American Geriatrics Society, 1978, Volume: 26, Issue:1 Topics: Aged; Amitriptyline; Aspirin; Blind Loop Syndrome; Diazepam; Enteritis; Female; Gastrointestinal Dis	1978
[The gefarnate-diazepam combination in the treatment of various gastrointestinal diseases]. La Clinica terapeutica, 1978, May-15, Volume: 85, Issue:3 Topics: Adult; Aged; Diazepam; Drug Combinations; Female; Gastrointestinal Diseases; Gefarnate; Humans; Male	1978
Fibre-endoscopy in gastrointestinal disease. II--Upper gastrointestinal tract. The Practitioner, 1976, Volume: 216, Issue:1295 Topics: Butylscopolammonium Bromide; Diazepam; Duodenal Ulcer; Duodenum; Endoscopy; Esophagoscopy; Fiber Opt	1976
Upper gastrointestinal endoscopy in the pediatric patient. Gastroenterology, 1976, Volume: 70, Issue:4 Topics: Age Factors; Anesthesia, Local; Child; Child, Preschool; Diazepam; Duodenal Ulcer; Endoscopy; Esopha	1976
Reduction of gastrointestinal symptoms following treatment for panic disorder. Psychosomatics, 1990,Winter, Volume: 31, Issue:1 Topics: Adult; Alprazolam; Anxiety Disorders; Colonic Diseases, Functional; Diazepam; Fear; Female; Gastroin	1990
The effect of age on the relative potency of midazolam and diazepam for sedation in upper gastrointestinal endoscopy. Journal of clinical gastroenterology, 1990, Volume: 12, Issue:2 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Cause of Death; Diazepam; Endoscopy; Female; Gastrointe	1990
Efficacy and safety of a diazepam and meperidine combination for pediatric gastrointestinal procedures. Journal of pediatric gastroenterology and nutrition, 1990, Volume: 10, Issue:3 Topics: Adolescent; Ambulatory Care; Child; Child, Preschool; Diazepam; Drug Combinations; Drug Evaluation;	1990
[Indications for diagnostic and surgical digestive endoscopy in childhood: personal clinical experience]. Acta bio-medica de L'Ateneo parmense : organo della Societa di medicina e scienze naturali di Parma, 1985, Volume: 56, Issue:2 Topics: Adolescent; Anesthesia, General; Atropine; Child; Child, Preschool; Diazepam; Endoscopy; Female; Gas	1985
There is an inverse relationship between the presence of significant endoscopic findings and the amount of diazepam required to obtain adequate sedation in upper endoscopy. Acta gastroenterologica Latinoamericana, 1987, Volume: 17, Issue:2 Topics: Diazepam; Endoscopy; Gastrointestinal Diseases; Humans; Premedication; Retrospective Studies	1987
[Reaction to the sudden withdrawal of diazepam in patients with anxiety neurosis]. Ceskoslovenska psychiatrie, 1986, Volume: 82, Issue:2 Topics: Anxiety Disorders; Diazepam; Gastrointestinal Diseases; Humans; Muscular Diseases; Substance Withdra	1986
Niacin and the schizophrenic patient. The American journal of psychiatry, 1970, Volume: 127, Issue:4 Topics: Diazepam; Edema; Gastrointestinal Diseases; Humans; Liver Function Tests; Mental Disorders; Niacinam	1970
Gastrointestinal endoscopy. Surgery annual, 1973, Volume: 5 Topics: Adolescent; Adult; Anesthesia; Biliary Tract; Biopsy; Cholangiography; Colon; Colonic Diseases; Diaz	1973
[Endoscopic observations in patients with gastroduodenopathies during treatment with a drug association with antivagal and tranquilizing action]. Minerva medica, 1967, Sep-01, Volume: 58, Issue:70 Topics: Adult; Aged; Diazepam; Endoscopy; Esophageal Diseases; Female; Gastrointestinal Diseases; Gastrointe	1967
[Therapeutic study of postoperative complications after stomach surgery using a new antivagal-anxiolytic drug combination]. Minerva medica, 1970, Jan-20, Volume: 61, Issue:6 Topics: Adult; Aged; Diazepam; Female; Gastroenterostomy; Gastrointestinal Diseases; Gastroscopy; Humans; Ma	1970
[Therapeutic clinical trial sedative Edym (capsules). Results obtained in 50 patients]. Revista espanola de las enfermedades del aparato digestivo, 1973, Nov-01, Volume: 41, Issue:5 Topics: Adult; Aged; Capsules; Cellulase; Diazepam; Drug Combinations; Evaluation Studies as Topic; Female;	1973
[Treatment of psychosomatic gastrointestinal disorders in ambulatory patients]. Minerva medica, 1973, Dec-05, Volume: 64, Issue:87 Topics: Adjustment Disorders; Adult; Aged; Ambulatory Care; Anxiety Disorders; Diazepam; Drug Combinations;	1973
[Paspertin (Metoclopramide) as a cause of dystonic-hyperkinetic syndromes in children]. Monatsschrift fur Kinderheilkunde, 1972, Volume: 120, Issue:2 Topics: Amides; Benzoates; Biperiden; Child; Diazepam; Female; Gastrointestinal Diseases; Humans; Hyperkines	1972
[Controlled therapeutic trial of gastroenteric diseases with psychogenic interference]. Minerva medica, 1970, Feb-17, Volume: 61, Issue:11 Topics: Adult; Aged; Diazepam; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Psychophysiolog	1970
[The psychotropic drugs in internal medicine: action of a new benzodiazepine (Nobrium)]. Il Policlinico. Sezione pratica, 1970, Jul-13, Volume: 77, Issue:28 Topics: Adult; Aged; Asthma; Biliary Tract Diseases; Cardiovascular Diseases; Diazepam; Female; Gastrointest	1970
[Relaxation--autonomic stabilization--sleep promotion--muscle relaxation]. Der Landarzt, 1967, Sep-30, Volume: 43, Issue:27 Topics: Cardiovascular Diseases; Central Nervous System Diseases; Diazepam; Dysautonomia, Familial; Female;	1967