Page last updated: 2024-10-25

diazepam and Cerebral Palsy, Athetoid

diazepam has been researched along with Cerebral Palsy, Athetoid in 38 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Research Excerpts

ExcerptRelevanceReference
"Diazepam was administered to seven severely affected athetoid children for a period of two to three months to determine whether beneficial effects could be demonstrated from its use."5.24DIAZEPAM: A PRELIMINARY STUDY OF ITS EFFECTS ON PATIENTS WITH ATHETOID CEREBRAL PALSY. ( ANGARA, VS; WHITTAKER, JS, 1965)
"Intrathecal baclofen is used in the management of spasticity associated with cerebral palsy (CP)."3.74Intravenous diazepam infusion in the management of planned intrathecal baclofen withdrawal. ( Cruikshank, M; Eunson, P, 2007)
" For management of postoperative muscle spasm, an intravenous benzodiazepine was used (diazepam 0."3.69Pain management for children following selective dorsal rhizotomy. ( Geiduschek, JM; Haberkern, CM; Hays, RM; Jacobson, LE; McLaughlin, JF; Roberts, TS, 1994)
"The results indicate that the spasticity of cerebral palsy can be relieved significantly, and that the combination of peripherally and centrally acting agents is more beneficial than either medication alone."2.64Medical treatment for spasticity in children with cerebral palsy. ( Nogen, AG, 1976)
"For localized/segmental spasticity, botulinum toxin type A is established as an effective treatment to reduce spasticity in the upper and lower extremities."2.46Practice parameter: pharmacologic treatment of spasticity in children and adolescents with cerebral palsy (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child ( Aisen, M; Ashwal, S; Delgado, MR; Fehlings, DL; Hirtz, D; McLaughlin, J; Morrison, LA; Shrader, MW; Tilton, A; Vargus-Adams, J, 2010)
"While in some children, spasticity may adversely impact the motor abilities, in others, it may help maintain posture and ability to ambulate."2.43Pharmacologic interventions for reducing spasticity in cerebral palsy. ( Patel, DR; Soyode, O, 2005)
"Isolated dystonia or spasticity was infrequently seen, with a mixed picture of dystonia and spasticity ± choreoathetosis identified in 194/275 (70."1.51Pharmacological management of abnormal tone and movement in cerebral palsy. ( Amin, S; Basu, A; Cadwgan, J; Crowe, B; DeAlwis, Y; Devlin, A; Kumar, R; Lodh, R; Lumsden, DE; Lundy, CT; Mordekar, SR; Smith, M, 2019)
"Diazepam was administered to seven severely affected athetoid children for a period of two to three months to determine whether beneficial effects could be demonstrated from its use."1.24DIAZEPAM: A PRELIMINARY STUDY OF ITS EFFECTS ON PATIENTS WITH ATHETOID CEREBRAL PALSY. ( ANGARA, VS; WHITTAKER, JS, 1965)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199031 (81.58)18.7374
1990's1 (2.63)18.2507
2000's3 (7.89)29.6817
2010's3 (7.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lumsden, DE1
Crowe, B1
Basu, A1
Amin, S1
Devlin, A1
DeAlwis, Y1
Kumar, R1
Lodh, R1
Lundy, CT1
Mordekar, SR1
Smith, M1
Cadwgan, J1
Awa, HD1
Chelo, D1
Kinkela, MN1
Ndombo, PO1
Delgado, MR1
Hirtz, D1
Aisen, M1
Ashwal, S1
Fehlings, DL1
McLaughlin, J1
Morrison, LA1
Shrader, MW1
Tilton, A1
Vargus-Adams, J1
RETT, A1
KANJILAL, GC2
GLOGOWSKI, G1
BARSA, JA1
SAUNDERS, JC1
CARTER, CH2
DENHOFF, E1
BOELSCHE, A1
DANFORD, BH1
SMITH, MC1
FERGUSON, WT1
MARSH, HO1
TARDIEU, G1
TARDIEU, C1
HARIGA, J1
ANGARA, VS1
WHITTAKER, JS1
SHERSHIN, PH1
KATZ, SS1
Mathew, A1
Mathew, MC1
Thomas, M1
Antonisamy, B1
Patel, DR1
Soyode, O1
Cruikshank, M1
Eunson, P1
Geiduschek, JM1
Haberkern, CM1
McLaughlin, JF1
Jacobson, LE1
Hays, RM1
Roberts, TS1
Vining, EP1
Accardo, PJ1
Rubenstein, JE1
Farrell, SE1
Roizen, NJ1
Nogen, AG1
Helwig, H1
Papeschi, R1
Molina-Negro, P1
Sourkes, TL1
Erba, G1
Schreiber, KA1
Schöning, B1
von Bazan, UB1
Koch, H1
Camp, EW1
Chyatte, SB1
Basmajian, JV1
Lydecken, K1
Rangdell, J1
Palomäki, S1
Holt, KS1
Griffiths, AP1
Sylvester, PE1
Engle, HA1
Hiller, CJ1
Mason, JL1
Hartmann-von Monakow, K1
Campbell, ED1
Green, EA1
Claverie, P1
Ousset, A1
Cahusac, M1
Nichil, J1
Wada, T1
Sakurada, S1
Furukori, T1
Saito, Y1
Yamahana, Y1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Radial Extracorporeal Shock Wave Therapy for Management of Spasticity in Patients With Cerebral Palsy[NCT05702606]73 participants (Actual)Interventional2021-06-10Completed
Sensory-Motor Rehabilitation Post Stroke[NCT02369770]140 participants (Anticipated)Interventional2019-04-26Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for diazepam and Cerebral Palsy, Athetoid

ArticleYear
Practice parameter: pharmacologic treatment of spasticity in children and adolescents with cerebral palsy (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child
    Neurology, 2010, Jan-26, Volume: 74, Issue:4

    Topics: Adolescent; Botulinum Toxins, Type A; Cerebral Palsy; Child; Clonidine; Diazepam; Humans; Muscle Rel

2010
Practice parameter: pharmacologic treatment of spasticity in children and adolescents with cerebral palsy (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child
    Neurology, 2010, Jan-26, Volume: 74, Issue:4

    Topics: Adolescent; Botulinum Toxins, Type A; Cerebral Palsy; Child; Clonidine; Diazepam; Humans; Muscle Rel

2010
Practice parameter: pharmacologic treatment of spasticity in children and adolescents with cerebral palsy (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child
    Neurology, 2010, Jan-26, Volume: 74, Issue:4

    Topics: Adolescent; Botulinum Toxins, Type A; Cerebral Palsy; Child; Clonidine; Diazepam; Humans; Muscle Rel

2010
Practice parameter: pharmacologic treatment of spasticity in children and adolescents with cerebral palsy (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child
    Neurology, 2010, Jan-26, Volume: 74, Issue:4

    Topics: Adolescent; Botulinum Toxins, Type A; Cerebral Palsy; Child; Clonidine; Diazepam; Humans; Muscle Rel

2010
Pharmacologic interventions for reducing spasticity in cerebral palsy.
    Indian journal of pediatrics, 2005, Volume: 72, Issue:10

    Topics: Administration, Oral; Adrenergic alpha-Agonists; Age Factors; Anti-Infective Agents, Local; Baclofen

2005
Cerebral palsy. A pediatric developmentalist's overview.
    American journal of diseases of children (1960), 1976, Volume: 130, Issue:6

    Topics: Cerebral Palsy; Dantrolene; Diazepam; Humans; Levodopa; Occupational Therapy; Phenothiazines; Physic

1976
[Psychopharmacological agents in children].
    Monatsschrift fur Kinderheilkunde, 1973, Volume: 121, Issue:3

    Topics: Acetylcholine; Aminobutyrates; Antipsychotic Agents; Cerebral Palsy; Child; Chlordiazepoxide; Diazep

1973

Trials

10 trials available for diazepam and Cerebral Palsy, Athetoid

ArticleYear
The efficacy of diazepam in enhancing motor function in children with spastic cerebral palsy.
    Journal of tropical pediatrics, 2005, Volume: 51, Issue:2

    Topics: Analysis of Variance; Cerebral Palsy; Child; Child, Preschool; Diazepam; Dose-Response Relationship,

2005
Medical treatment for spasticity in children with cerebral palsy.
    Child's brain, 1976, Volume: 2, Issue:5

    Topics: Cerebral Palsy; Child; Child, Preschool; Clinical Trials as Topic; Dantrolene; Diazepam; Female; Hum

1976
[Ketamine and diazepam for anaesthesia in infantile cerebral palsy (author's transl)].
    Der Anaesthesist, 1974, Volume: 23, Issue:1

    Topics: Adolescent; Anesthesia, Intravenous; Anesthetics, Dissociative; Cerebral Palsy; Child; Child, Presch

1974
Dantrolene sodium: long-term effects in severe spasticity.
    Archives of physical medicine and rehabilitation, 1973, Volume: 54, Issue:7

    Topics: Activities of Daily Living; Adolescent; Adult; Alkaline Phosphatase; Aspartate Aminotransferases; Ce

1973
Evaluation of diazepam in skeletal muscle hypertonicity in cerebral palsy.
    Archives of physical medicine and rehabilitation, 1968, Volume: 49, Issue:9

    Topics: Adolescent; Adult; Athetosis; Cerebral Palsy; Child; Child, Preschool; Clinical Trials as Topic; Dia

1968
The use of diazepam in childhood cerebral palsy. Report of a small study including electromyographic observations.
    Annals of physical medicine, 1964, Volume: Suppl

    Topics: Cerebral Palsy; Child; Child, Preschool; Clinical Trials as Topic; Diazepam; Electromyography; Human

1964
Clinical trial of diazepam in adult cerebral palsy.
    Annals of physical medicine, 1964, Volume: Suppl

    Topics: Adolescent; Adult; Aged; Cerebral Palsy; Child; Clinical Trials as Topic; Diazepam; Female; Humans;

1964
Some observations on clinical trials with diazepam in cerebral palsy.
    Annals of physical medicine, 1964, Volume: Suppl

    Topics: Cerebral Palsy; Child; Child, Preschool; Clinical Trials as Topic; Diazepam; Humans; Placebos

1964
The effect of diazepam (Valium) in children with cerebral palsy: a double-blind study.
    Developmental medicine and child neurology, 1966, Volume: 8, Issue:6

    Topics: Adolescent; Behavior; Cerebral Palsy; Child; Child, Preschool; Clinical Trials as Topic; Diazepam; F

1966
Therapeutic test of diazepam (valium) in cerebral palsy.
    Journal of the South Carolina Medical Association (1975), 1966, Volume: 62, Issue:8

    Topics: Cerebral Palsy; Child; Clinical Trials as Topic; Diazepam; Humans

1966

Other Studies

24 other studies available for diazepam and Cerebral Palsy, Athetoid

ArticleYear
Pharmacological management of abnormal tone and movement in cerebral palsy.
    Archives of disease in childhood, 2019, Volume: 104, Issue:8

    Topics: Adolescent; Baclofen; Botulinum Toxins; Cerebral Palsy; Child; Child Health Services; Child, Prescho

2019
[Patent rickets disclosed by loss of convulsion control in a boy with cerebral palsy].
    The Pan African medical journal, 2013, Volume: 14

    Topics: Anticonvulsants; Calcium; Carbamazepine; Cerebral Palsy; Child, Preschool; Diazepam; Epilepsy; Human

2013
[ON THE CLINICAL ASPECTS AND THERAPY OF PYRAMIDAL AND EXTRAPYRAMIDAL MOVEMENT DISORDERS].
    Wiener klinische Wochenschrift, 1963, Oct-25, Volume: 75

    Topics: Athetosis; Basal Ganglia Diseases; Cerebral Palsy; Child; Chorea; Diazepam; Extrapyramidal Tracts; H

1963
A CLINICAL EVALUATION OF 'VALIUM' (RO5-2807) IN CEREBRAL PALSY.
    The British journal of clinical practice, 1964, Volume: 18

    Topics: Adolescent; Aging; Cerebral Palsy; Child; Diazepam; Physical Therapy Modalities; Toxicology; Tranqui

1964
[CURRENT PROBLEMS OF SPASTIC PARALYSIS OF THE EXTREMITIES].
    Munchener medizinische Wochenschrift (1950), 1963, Dec-06, Volume: 105

    Topics: Adolescent; Cerebral Palsy; Child; Diazepam; Electromyography; Handwriting; Muscle Spasticity; Paral

1963
COMPARATIVE STUDY OF CHLORDIAZEPOXIDE AND DIAZEPAM.
    Diseases of the nervous system, 1964, Volume: 25

    Topics: Cerebral Palsy; Chlordiazepoxide; Diazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Int

1964
A CONTROLLED EVALUATION OF TWO BENZODIAZEPINE DERIVATES IN THE MANAGEMENT OF MENTALLY RETARDED, CEREBRAL-PALSIED PATIENTS.
    Medical times, 1964, Volume: 92

    Topics: Adolescent; Anticonvulsants; Athetosis; Benzodiazepines; Biomedical Research; Cerebral Palsy; Child;

1964
DIAZEPAM (VALIUM) IN CEREBRAL PALSY. A COMPARISON OF UNCONTROLLED OFFICE STUDIES VERSUS A CONTROLLED TEAM STUDY.
    Rhode Island medical journal, 1964, Volume: 47

    Topics: Biomedical Research; Cerebral Palsy; Child; Diazepam; Research Design; Toxicology

1964
DRUG THERAPY IN CEREBRAL PALSY. CURRENT STATUS.
    Texas state journal of medicine, 1964, Volume: 60

    Topics: Adolescent; Biomedical Research; Cerebral Palsy; Child; Diazepam; Drug Therapy; Toxicology

1964
PILOT STUDY IN THE USE OF DIAZEPAM (VALIUM) IN CEREBRAL PALSY.
    The Nebraska state medical journal, 1964, Volume: 49

    Topics: Adolescent; Athetosis; Cerebral Palsy; Child; Diazepam; Drug Therapy; Humans; Infant; Paraplegia; Pi

1964
DIAZEPAM IN INCAPACITATED CEREBRAL-PALSIED CHILDREN.
    JAMA, 1965, Mar-08, Volume: 191

    Topics: Adolescent; Biomedical Research; Cardiovascular Agents; Cerebral Palsy; Child; Chlordiazepoxide; Dia

1965
[ACTION OF VALIUM ON EXPERIMENTAL DECEREBRATE RIGIDITY AND ON RIGIDITY OF CHILDREN WITH CERBRAL MOTOR DISEASE].
    Acta neurologica et psychiatrica Belgica, 1964, Volume: 64

    Topics: Cats; Cerebral Palsy; Child; Decerebrate State; Diazepam; Humans; Nervous System Diseases

1964
DIAZEPAM: A PRELIMINARY STUDY OF ITS EFFECTS ON PATIENTS WITH ATHETOID CEREBRAL PALSY.
    Canadian Medical Association journal, 1965, Aug-21, Volume: 93

    Topics: Adolescent; Athetosis; Cerebral Palsy; Child; Conduct Disorder; Diazepam; Drug Therapy; Drug-Related

1965
DIAZEPAM IN THE TREATMENT OF TETANUS: REPORT OF A CASE FOLLOWING TOOTH EXTRACTION.
    Clinical medicine (Northfield, Ill.), 1964, Volume: 71

    Topics: Adolescent; Cerebral Palsy; Diagnosis; Diazepam; Humans; Muscle Relaxants, Central; Penicillins; Pos

1964
Intravenous diazepam infusion in the management of planned intrathecal baclofen withdrawal.
    Developmental medicine and child neurology, 2007, Volume: 49, Issue:8

    Topics: Adolescent; Adult; Anticonvulsants; Baclofen; Cerebral Palsy; Child; Diazepam; Drug Administration S

2007
Pain management for children following selective dorsal rhizotomy.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:6

    Topics: Adolescent; Adult; Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Bupiva

1994
The concentration of homovanillic and 5-hydroxyindoleacetic acids in ventricular and lumbar CSF. Studies in patients with extrapyramidal disorders, epilepsy, and other diseases.
    Neurology, 1972, Volume: 22, Issue:11

    Topics: Adolescent; Adult; Basal Ganglia Diseases; Cerebral Palsy; Cerebral Ventricles; Diazepam; Dihydroxyp

1972
[Therapy of cerebral seizures in multiple-handicapped children].
    Fortschritte der Medizin, 1973, Dec-06, Volume: 91, Issue:34

    Topics: Anticonvulsants; Barbiturates; Cerebral Palsy; Child; Child, Preschool; Diazepam; Disabled Persons;

1973
Letter: Drug therapy of cerebral palsy.
    Journal of the South Carolina Medical Association (1975), 1974, Volume: 70, Issue:12

    Topics: Anxiety; Cerebral Palsy; Diazepam; Drug Therapy, Combination; Gout; Humans; Male; Probenecid

1974
[Experiences on premedication in dental treatment of CP- and mentally retarded patients].
    Suomen Hammaslaakariseuran toimituksia = Finska tandlakarsallskapets forhandlingar, 1969, Volume: 65, Issue:3

    Topics: Adolescent; Adult; Cerebral Palsy; Child; Child, Preschool; Chlorprothixene; Dental Restoration, Per

1969
[Therapy of cerebral infantile paralysis].
    Bibliotheca psychiatrica et neurologica, 1969, Volume: 139

    Topics: Age Factors; Cerebral Palsy; Diazepam; Female; Humans; Infant; Infant, Newborn; Occupational Therapy

1969
Treatment of cerebral palsy in the severely subnormal.
    Rheumatology and physical medicine, 1970, Volume: 10, Issue:8

    Topics: Carisoprodol; Cerebral Palsy; Child; Child, Preschool; Diazepam; Female; Humans; Hydrotherapy; Intel

1970
[Effect of diazepam on athetosic children with cerebral palsy].
    Revue de neuropsychiatrie infantile et d'hygiene mentale de l'enfance, 1968, Volume: 16, Issue:12

    Topics: Adolescent; Athetosis; Cerebral Palsy; Child; Child, Preschool; Diazepam; Humans

1968
[Combined use of Tegretol and Diazepam for the therapy of central nervous system rigido-spasticity].
    No to shinkei = Brain and nerve, 1966, Volume: 18, Issue:5

    Topics: Adult; Anticonvulsants; Cerebral Palsy; Child; Child, Preschool; Diazepam; Female; Humans; Infant; M

1966