Compounds > diazepam
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diazepam and Catatonic Rigidity

diazepam has been researched along with Catatonic Rigidity in 43 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Research Excerpts

ExcerptRelevanceReference
"Clinical history, neurologic investigations, course, EMG findings, muscle biopsy and response to diazepam treatment in two patients fulfilled criteria established by Gordon, Januszko and Kaufman for the diagnosis of the stiff-man syndrome."3.67[2 cases of stiff-man syndrome with tremor]. ( Cunha, L; Diniz, MA; Gonçalves, F; Oliveira, C, 1986)
"Conservative management of 11 consecutive cases of tetanus with diazepam in heavy doses and methocarbamol is described."3.65Tetanus: conservative management made easier by combination of muscle relaxants. ( Anah, CO, 1974)
"Treatment with diazepam led to resolution of spasticity, whereas repeated courses of intravenous immunoglobulin improved cerebellar function, including appendicular ataxia and downbeating nystagmus."1.33Downbeating nystagmus and muscle spasms in a patient with glutamic-acid decarboxylase antibodies. ( Ances, BM; Dalmau, JO; Galetta, SL; Hasbani, MJ; Tsai, J, 2005)
"Group III served as control."1.28[Muscular rigidity caused by alfentanil: prevention]. ( Curatolo, M; Di Giandomenico, E; Maggio, G; Montanini, S; Santamaria, LB; Sinardi, AU; Venuti, FS, 1989)
"Diazepam was without effect on the extensor reflex in spinal rats."1.27Pharmacological studies of 1-(2,3-dimethyl-4-methoxyphenyl)-2-methyl-3-(1-pyrrolidinyl)-1- propanone hydrochloride (AD-2239), a centrally acting muscle relaxant. ( Furukawa, K; Hori, M; Ito, T; Kadokawa, T; Karasawa, T, 1985)
"Ketamine, ketamine-xylazine, and ketamine-diazepam were evaluated clinically in 15 ferrets, and safe dosage was determined for each."1.27Evaluation of ketamine, ketamine-xylazine and ketamine-diazepam anesthesia in the ferret. ( Glaser, C; Moreland, AF, 1985)
"A female patient had permanent axial muscular rigidity similar to the "stiff-man syndrome", together with axial myoclonus triggered by stretch reflexes and by supramaximal stimulation of the supraorbital nerve."1.26Jerking stiff-man syndrome. ( Alberca, R; Chaparro, J; Romero, M, 1982)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199036 (83.72)18.7374
1990's1 (2.33)18.2507
2000's2 (4.65)29.6817
2010's3 (6.98)24.3611
2020's1 (2.33)2.80

Authors

AuthorsStudies
Shen, D1
Zhou, H1
Chen, S1
Mathew, PJ1
Samra, T1
Wig, J1
Dagtekin, O1
Marcus, H1
Müller, C1
Böttiger, BW1
Spöhr, F1
Lavezzi, WA1
Capacchione, JF1
Muldoon, SM1
Sambuughin, N1
Bina, S1
Steele, D1
Brandom, BW1
Ances, BM1
Dalmau, JO1
Tsai, J1
Hasbani, MJ1
Galetta, SL1
Jain, S1
Ashok, PP1
Maheshwari, MC1
Meinck, HM2
Ricker, K1
Conrad, B2
Kawajiri, S1
Kojima, H1
Akashi, A1
Lossius, R1
Dietrichson, P1
Lunde, PK1
Alberca, R1
Romero, M1
Chaparro, J1
Daras, M1
Spiro, AJ1
Fujiya, S1
Maida, E1
Reisner, T1
Summer, K1
Sandor-Eggerth, H1
Whelan, JL1
Gouider-Khouja, N1
Mekaouar, A1
Larnaout, A1
Miladi, N1
Ben Khelifa, F1
Hentati, F1
Nyland, H1
Mellgren, SI1
Frövig, AG1
Fukuda, H1
Westblom, U2
Altuzarra Corral, LM1
Velicia Llames, MR1
Fernández Herranz, MR1
From, A1
Heltberg, A1
Calne, DB1
Schmidt, RT1
Stahl, SM1
Spehlmann, R1
Share, NN1
McFarlane, CS1
Blum, P1
Jankovic, J1
Rapport, DJ1
Covington, EC1
Venuti, FS1
Curatolo, M1
Sinardi, AU1
Santamaria, LB1
Di Giandomenico, E1
Maggio, G1
Montanini, S1
Diniz, MA1
Cunha, L1
Gonçalves, F1
Oliveira, C1
Watanabe, K1
Weinger, MB1
Sanford, TJ1
Smith, NT1
Masson, C1
Prier, S1
Benoit, C1
Henin, D1
Masson, M1
Cambier, J1
Moldovanu, IV1
Chubar', AV1
Chuchin, MIu1
Ito, T1
Hori, M1
Furukawa, K1
Karasawa, T1
Kadokawa, T1
Moreland, AF1
Glaser, C1
White, C1
Richens, A1
Maxwell, DR2
Read, MA2
Sumpter, EA1
Smith, MJ1
Kendall, BE1
Tomlinson, S1
Anah, CO1
Barnett, A1
Goldstein, J1
Fiedler, EP1
Taber, RI1
Hoch, FL1
Hogan, FP1
Lhermitte, F1
Chain, F1
Escourolle, R1
Chedru, F1
Guilleminault, C1
Francoual, M1

Reviews

3 reviews available for diazepam and Catatonic Rigidity

ArticleYear
Drug treatment of spasticity and rigidity.
    Modern trends in neurology, 1975, Volume: 6

    Topics: Amantadine; Baclofen; Diazepam; Humans; Levodopa; Mephenesin; Muscle Rigidity; Parasympatholytics; P

1975
Stiff-person syndrome: an autoimmune disease.
    Movement disorders : official journal of the Movement Disorder Society, 1991, Volume: 6, Issue:1

    Topics: Autoantibodies; Autoimmune Diseases; Baclofen; Diazepam; Drug Administration Schedule; Drug Therapy,

1991
[The stiff-man syndrome].
    Nihon rinsho. Japanese journal of clinical medicine, 1987, Volume: 45, Issue:2

    Topics: Baclofen; Diazepam; Humans; Muscle Rigidity; Muscle Spasticity; Syndrome; Valproic Acid

1987

Trials

3 trials available for diazepam and Catatonic Rigidity

ArticleYear
Magnesium sulphate for treatment of tetanus in adults.
    Anaesthesia and intensive care, 2010, Volume: 38, Issue:1

    Topics: Adult; Aged; Autonomic Nervous System Diseases; Cohort Studies; Diazepam; Disease Progression; Femal

2010
A double-blind trial with baclofen (Lioresal) and diazepam in spasticity due to multiple sclerosis.
    Acta neurologica Scandinavica, 1975, Volume: 51, Issue:2

    Topics: Adult; Aged; Aminobutyrates; Chlorobenzenes; Clinical Trials as Topic; Diazepam; Drug Evaluation; Fe

1975
Letter: Thymoxamine and spasticity.
    Lancet (London, England), 1974, Volume: 1, Issue:7859

    Topics: Administration, Oral; Clinical Trials as Topic; Diazepam; Humans; Injections, Intravenous; Moxisylyt

1974

Other Studies

37 other studies available for diazepam and Catatonic Rigidity

ArticleYear
Spasms and Myoclonus in a Young Woman With Hashimoto Thyroiditis.
    JAMA neurology, 2020, 05-01, Volume: 77, Issue:5

    Topics: Adult; Anticonvulsants; Clonazepam; Diazepam; Encephalomyelitis; Female; Hashimoto Disease; Humans;

2020
Lipid therapy for serotonin syndrome after intoxication with venlafaxine, lamotrigine and diazepam.
    Minerva anestesiologica, 2011, Volume: 77, Issue:1

    Topics: Adult; Combined Modality Therapy; Cyclohexanols; Diazepam; Emulsions; Fat Emulsions, Intravenous; Fe

2011
Case report: Death in the emergency department: an unrecognized awake malignant hyperthermia-like reaction in a six-year-old.
    Anesthesia and analgesia, 2013, Volume: 116, Issue:2

    Topics: Child; Diazepam; Emergency Medical Services; Emergency Service, Hospital; Fatal Outcome; Humans; Hyp

2013
Downbeating nystagmus and muscle spasms in a patient with glutamic-acid decarboxylase antibodies.
    American journal of ophthalmology, 2005, Volume: 140, Issue:1

    Topics: Autoantibodies; Diazepam; Diplopia; Drug Therapy, Combination; Female; Glutamate Decarboxylase; Huma

2005
Local tetanus: a case report with electrophysiological studies.
    Journal of neurology, 1982, Volume: 228, Issue:4

    Topics: Diazepam; Electromyography; Humans; Male; Middle Aged; Muscle Rigidity; Tetanus; Thiopental

1982
The stiff-man syndrome: new pathophysiological aspects from abnormal exteroceptive reflexes and the response to clomipramine, clonidine, and tizanidine.
    Journal of neurology, neurosurgery, and psychiatry, 1984, Volume: 47, Issue:3

    Topics: Adult; Brain Stem; Clomipramine; Clonidine; Diazepam; Electromyography; Female; Humans; Muscle Rigid

1984
[A comparison of the effects of baclofen and some other muscle relaxants on alpha-rigidity in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1984, Volume: 83, Issue:3

    Topics: Animals; Baclofen; Brain Ischemia; Chlordiazepoxide; Dantrolene; Decerebrate State; Diazepam; Male;

1984
Effect of diazepam and desmethyldiazepam in spasticity and rigidity. A quantitative study of reflexes and plasma concentrations.
    Acta neurologica Scandinavica, 1980, Volume: 61, Issue:6

    Topics: Adult; Diazepam; Female; Humans; Injections, Intravenous; Male; Middle Aged; Muscle Rigidity; Muscle

1980
Jerking stiff-man syndrome.
    Journal of neurology, neurosurgery, and psychiatry, 1982, Volume: 45, Issue:12

    Topics: Adult; Baclofen; Diazepam; Female; Humans; Muscle Rigidity; Myoclonus; Spasm

1982
'Stiff-man syndrome' in an adolescent.
    Pediatrics, 1981, Volume: 67, Issue:5

    Topics: Adolescent; Age Factors; Child; Diagnosis, Differential; Diazepam; Electrodiagnosis; Humans; Male; M

1981
[Characteristics of respiratory physiology in a case of stiff-man syndrome (author's transl)].
    Nihon Kyobu Shikkan Gakkai zasshi, 1981, Volume: 19, Issue:11

    Topics: Diazepam; Humans; Hypercapnia; Male; Middle Aged; Muscle Rigidity; Respiration; Respiratory Function

1981
Stiff-man syndrome with abnormalities in CSF and computerized tomography findings. Report of a case.
    Archives of neurology, 1980, Volume: 37, Issue:3

    Topics: Atrophy; Cerebrospinal Fluid Proteins; Diazepam; Female; Humans; Immunoglobulin G; Middle Aged; Musc

1980
Baclofen in treatment of the 'stiff-man' syndrome.
    Archives of neurology, 1980, Volume: 37, Issue:9

    Topics: Adult; Baclofen; Diazepam; Drug Therapy, Combination; Humans; Male; Muscle Rigidity; Spasm

1980
Progressive encephalomyelitis with rigidity presenting as a stiff-person syndrome.
    Parkinsonism & related disorders, 2002, Volume: 8, Issue:4

    Topics: Anti-Inflammatory Agents; Baclofen; Diagnosis, Differential; Diazepam; Drug Therapy, Combination; El

2002
Stiff-man syndrome with central and peripheral nervous manifestations.
    Journal of neurology, 1978, Dec-07, Volume: 219, Issue:3

    Topics: Clonazepam; Diazepam; Electromyography; Humans; Male; Middle Aged; Muscle Rigidity; Muscles; NADH, N

1978
[Effects of diazepam and baclofen on the anemic decerebrate rigidity in rats (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1979, Volume: 75, Issue:6

    Topics: Aminooxyacetic Acid; Animals; Baclofen; Brain; Decerebrate State; Depression, Chemical; Diazepam; Di

1979
Stiff-man syndrome and clonazepam.
    JAMA, 1977, May-02, Volume: 237, Issue:18

    Topics: Benzodiazepinones; Clonazepam; Diazepam; Female; Humans; Middle Aged; Muscle Rigidity; Spasm; Syndro

1977
[Stiff--man syndrome].
    Lakartidningen, 1978, Mar-22, Volume: 75, Issue:12

    Topics: Clonazepam; Diagnosis, Differential; Diazepam; Female; Humans; Middle Aged; Muscle Rigidity; Syndrom

1978
[Stiff man syndrome. Report of a case].
    Revista clinica espanola, 1977, Mar-15, Volume: 144, Issue:5

    Topics: Adult; Diazepam; Humans; Male; Muscle Rigidity

1977
A pharmacologic study of the stiff-man syndrome. Correlation of clinical symptoms with urinary 3-methoxy-4-hydroxy-phenyl glycol excretion.
    Neurology, 1975, Volume: 25, Issue:7

    Topics: Diazepam; Glycine; Glycols; Homovanillic Acid; Humans; Levodopa; Male; Metanephrine; Methoxyhydroxyp

1975
Cyclobenzaprine: novel centrally acting skeletal muscle relaxant.
    Neuropharmacology, 1975, Volume: 14, Issue:9

    Topics: Amitriptyline; Animals; Anticonvulsants; Ataxia; Cats; Chlorpromazine; Decerebrate State; Diazepam;

1975
Motor phenomena in benzodiazepine withdrawal.
    Hospital & community psychiatry, 1989, Volume: 40, Issue:12

    Topics: Aged; Alprazolam; Anti-Anxiety Agents; Diagnosis, Differential; Diazepam; Drug Therapy, Combination;

1989
[Muscular rigidity caused by alfentanil: prevention].
    Minerva anestesiologica, 1989, Volume: 55, Issue:6

    Topics: Adolescent; Adult; Age Factors; Alfentanil; Body Weight; Diazepam; Humans; Middle Aged; Muscle Rigid

1989
[2 cases of stiff-man syndrome with tremor].
    Revue neurologique, 1986, Volume: 142, Issue:12

    Topics: Contracture; Diazepam; Humans; Male; Middle Aged; Muscle Rigidity; Myoclonus; Receptors, GABA-A; Syn

1986
Do dopaminergic drugs really prevent opiate-induced rigidity?
    Anesthesia and analgesia, 1988, Volume: 67, Issue:9

    Topics: Amantadine; Diazepam; Dopamine; Humans; Muscle Rigidity; Narcotics

1988
[Amnesia and stiff-man syndrome. Manifestations disclosing paraneoplastic encephalomyelitis].
    Annales de medecine interne, 1987, Volume: 138, Issue:7

    Topics: Amnesia; Brain; Contracture; Diazepam; Electromyography; Encephalomyelitis; Humans; Male; Middle Age

1987
Neuropharmacological investigations in the stiff-man syndrome.
    Journal of neurology, 1986, Volume: 233, Issue:6

    Topics: Adrenergic Fibers; Central Nervous System Diseases; Clonidine; Diazepam; Female; Humans; Methampheta

1986
[The stiff man syndrome].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1986, Volume: 86, Issue:11

    Topics: Adult; Diagnosis, Differential; Diazepam; Female; Follow-Up Studies; Humans; Muscle Rigidity; Spasm;

1986
Pharmacological studies of 1-(2,3-dimethyl-4-methoxyphenyl)-2-methyl-3-(1-pyrrolidinyl)-1- propanone hydrochloride (AD-2239), a centrally acting muscle relaxant.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 275, Issue:1

    Topics: Animals; Arousal; Baclofen; Behavior, Animal; Cats; Decerebrate State; Diazepam; Electroencephalogra

1985
Evaluation of ketamine, ketamine-xylazine and ketamine-diazepam anesthesia in the ferret.
    Laboratory animal science, 1985, Volume: 35, Issue:3

    Topics: Anesthesia, General; Animals; Animals, Laboratory; Arrhythmias, Cardiac; Carnivora; Diazepam; Electr

1985
Pharmacology of M & B 18,706, a drug which selectively reduces decerebrate rigidity.
    British journal of pharmacology, 1974, Volume: 50, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Apomorphine; Cats; Cerebellar Ataxia; Cerebellum; Chlorpromaz

1974
Adverse general reactions to high doses of methylglucamine-based contrast media.
    The British journal of radiology, 1974, Volume: 47, Issue:561

    Topics: Adipates; Adult; Age Factors; Alkaline Phosphatase; Amino Sugars; Calcium; Chlorpheniramine; Contras

1974
Tetanus: conservative management made easier by combination of muscle relaxants.
    The American journal of tropical medicine and hygiene, 1974, Volume: 23, Issue:5

    Topics: Adolescent; Child; Diazepam; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Mal

1974
The pharmacology of fletazepam a centrally-acting muscle relaxant.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 212, Issue:1

    Topics: Aggression; Animals; Anticonvulsants; Avoidance Learning; Benzazepines; Benzodiazepines; Cats; Diaze

1974
The effects of some drugs on the rigidity of the cat due to ischaemic or intercollicular decerebration.
    Neuropharmacology, 1972, Volume: 11, Issue:6

    Topics: Acepromazine; Animals; Carisoprodol; Cats; Cerebrovascular Circulation; Chlorpromazine; Decerebrate

1972
Hyperthermia, muscle rigidity, and uncoupling in skeletal muscle mitochondria in rats treated with halothane and 2,4-dinitrophenol.
    Anesthesiology, 1973, Volume: 38, Issue:3

    Topics: Anesthesia, Inhalation; Animals; Body Temperature; Dactinomycin; Diazepam; Dinitrophenols; Drug Syne

1973
[A further case of tetanus-like contracture distinct from the stiff man syndrome. Pharmacological and neuropathological study of a case of predominantly spinal encephalomyelitis].
    Revue neurologique, 1973, Volume: 128, Issue:1

    Topics: Aged; Carbamazepine; Contracture; Diazepam; Dihydroxyphenylalanine; Electromyography; Encephalomyeli

1973