Page last updated: 2024-10-25

diazepam and Catatonia

diazepam has been researched along with Catatonia in 33 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Catatonia: A neuropsychiatric disorder characterized by one or more of the following essential features: immobility, mutism, negativism (active or passive refusal to follow commands), mannerisms, stereotypies, posturing, grimacing, excitement, echolalia, echopraxia, muscular rigidity, and stupor; sometimes punctuated by sudden violent outbursts, panic, or hallucinations. This condition may be associated with psychiatric illnesses (e.g., SCHIZOPHRENIA; MOOD DISORDERS) or organic disorders (NEUROLEPTIC MALIGNANT SYNDROME; ENCEPHALITIS, etc.). (From DSM-IV, 4th ed, 1994; APA, Thesaurus of Psychological Index Terms, 1994)

Research Excerpts

ExcerptRelevanceReference
"The lorazepam-diazepam protocol can rapidly relieve retarded catatonia in schizophrenia."9.17Lorazepam-diazepam protocol for catatonia in schizophrenia: a 21-case analysis. ( Huang, TL; Lin, CC, 2013)
"The lorazepam-diazepam protocol had been proved to rapidly and effectively relieve catatonia in patients with schizophrenia or mood disorder."7.85The Lorazepam and Diazepam Protocol for Catatonia Due to General Medical Condition and Substance in Liaison Psychiatry. ( Huang, TL; Hung, YY; Lin, CC; Tsai, MC, 2017)
"We report a case of malignant catatonia initially diagnosed as neuroleptic malignant syndrome (NMS) that responded successfully to diazepam administration."7.77[Diazepam-responsive malignant catatonia in a patient with an initial clinical diagnosis of neuroleptic malignant syndrome: a case report]. ( Higuchi, MA; Mishima, T; Obata, T; Tsuboi, Y; Tsugawa, J; Yamada, T, 2011)
"This article describes a patient with lethal catatonia: treatment by ECT alone was ineffective, whereas continued treatment with ECT in combination with dantrolene sodium led to improvement."5.28Treatment of lethal catatonia with electroconvulsive therapy and dantrolene sodium: a case report. ( Nolen, WA; Zwaan, WA, 1990)
"The lorazepam-diazepam protocol can rapidly relieve retarded catatonia in schizophrenia."5.17Lorazepam-diazepam protocol for catatonia in schizophrenia: a 21-case analysis. ( Huang, TL; Lin, CC, 2013)
"A 19-year-old male came to the Emergency Room of our hospital due to an episode of dystonic movements and disorientation 4 days after consuming methamphetamine, which evolved to a catatonic frank syndrome and eventually to status epilepticus."3.85Anti-NMDA (a-NMDAR) receptor encephalitis related to acute consumption of metamphetamine: Relevance of differential diagnosis. ( Aguilera, L; García, JM; Iriondo, O; Rodríguez, T; Zaldibar-Gerrikagoitia, J, 2017)
"Patients with catatonia who had more than one episode of catatonia and were treated with the lorazepam-diazepam protocol were identified."3.83Relapses and recurrences of catatonia: 30-case analysis and literature review. ( Huang, TL; Hung, YY; Lin, CC; Tsai, MC, 2016)
" He developed neuroleptic malignant syndrome (NMS) which was treated successfully with intravenous diazepam."3.69Catatonic syndrome following recovery from neuroleptic malignant syndrome. ( Dent, J, 1995)
"Malignant catatonia, associated with different somatic and psychiatric disorders, is a rare, life-threatening syndrome."2.40[Acute life threatening catatonia--clinical significance and therapeutic possibilities]. ( Bridler, R; Hell, D, 1997)
"Her maximum score on the Bush-Francis Catatonia Rating Scale (BFCRS) was 15/69 on day 2 of her stay."1.91Celiac disease and catatonia: more than a coincidence? ( Gücüyener, K; Karaduman, AE; Menderes, DK; Özbudak, P; Öztürk, H, 2023)
"Thus, physician should consider catatonia when treating neuroleptic malignant like syndrome."1.36[Case with difficulty in differentiating between transient neuroleptic malignant syndrome and catatonia after neuroleptic analgesia]. ( Miyazaki, M; Yanagawa, Y, 2010)
" We treated catatonic symptoms with drugs within the upper limit of dosage and electroconvulsive therapy (ECT) to determine the maximal response."1.34Maximal response to electroconvulsive therapy for the treatment of catatonic symptoms. ( Arai, H; Hatta, K; Miyakawa, K; Nakamura, H; Ota, T; Usui, C, 2007)
"However, there are rare cases of catatonia being described in SLE."1.33Benzodiazepines in catatonia associated with systemic lupus erythematosus. ( Huang, TL; Wang, HY, 2006)
"Two had organic catatonic disorder and the third organic depressive disorder."1.30The treatment of stupor associated with MRI evidence of cerebrovascular disease. ( Herzberg, J; Ranger, M; Spear, J, 1997)
"Catatonia has not previously been described."1.29Catatonia after benzodiazepine withdrawal. ( Mazurek, MF; Rosebush, PI, 1996)
"Separate episodes of both catatonia and the so-called 'neuroleptic malignant syndrome' (NMS) occurred within the same patient."1.28Catatonia and the neuroleptic malignant syndrome--a single entity? ( White, DA, 1992)
"This article describes a patient with lethal catatonia: treatment by ECT alone was ineffective, whereas continued treatment with ECT in combination with dantrolene sodium led to improvement."1.28Treatment of lethal catatonia with electroconvulsive therapy and dantrolene sodium: a case report. ( Nolen, WA; Zwaan, WA, 1990)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19905 (15.15)18.7374
1990's13 (39.39)18.2507
2000's4 (12.12)29.6817
2010's10 (30.30)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Özbudak, P1
Karaduman, AE1
Menderes, DK1
Öztürk, H1
Gücüyener, K1
Banerjee, D1
Lin, CC3
Huang, TL6
Margetić, B1
Palijan, TZ1
Kovacević, D1
Hung, YY3
Tsai, MC3
Iriondo, O1
Zaldibar-Gerrikagoitia, J1
Rodríguez, T1
García, JM1
Aguilera, L1
Iseki, K1
Ikeda, A1
Kihara, T1
Kawamoto, Y1
Mezaki, T1
Hanakawa, T1
Hashikawa, K1
Fukuyama, H1
Shibasaki, H1
Yanagawa, Y1
Miyazaki, M1
Mishima, T1
Tsuboi, Y1
Higuchi, MA1
Tsugawa, J1
Obata, T1
Yamada, T1
Dada, MU1
Oluwole, L1
Obadeji, A1
Ajayi, OA1
Wang, HY1
Hatta, K1
Miyakawa, K1
Ota, T1
Usui, C1
Nakamura, H1
Arai, H1
Atri, PB1
Julius, DA1
Louis, ED1
Pflaster, NL1
Ungvari, GS2
Leung, HC1
Lee, TS1
Leung, CM1
Wong, MK1
Lau, J1
Lee, WY1
Joseph, WY1
Dent, J1
Lee, JW1
Rosebush, PI1
Mazurek, MF1
Miyaoka, H1
Shishikura, K1
Otsubo, T1
Muramatsu, D1
Kamijima, K1
Spear, J1
Ranger, M1
Herzberg, J1
Bridler, R1
Hell, D1
Winters, WD1
Kott, KS1
White, DA1
Sivakumar, K1
Mills, CS1
Gupta, K1
Nolen, WA1
Zwaan, WA1
Wetzel, H1
Heuser, I1
Benkert, O1
de Pauw, KW1
Szulecka, TK1
Baliarda, A1

Reviews

2 reviews available for diazepam and Catatonia

ArticleYear
Homicide and subsequent catatonia associated with a large arachnoid cyst: case report.
    Acta clinica Croatica, 2013, Volume: 52, Issue:4

    Topics: Adult; Antipsychotic Agents; Arachnoid Cysts; Catatonia; Clozapine; Delusions; Diazepam; Homicide; H

2013
[Acute life threatening catatonia--clinical significance and therapeutic possibilities].
    Schweizerische medizinische Wochenschrift, 1997, Sep-13, Volume: 127, Issue:37

    Topics: Adult; Biperiden; Catatonia; Clopenthixol; Clozapine; Diagnosis, Differential; Diazepam; Drug Admini

1997

Trials

2 trials available for diazepam and Catatonia

ArticleYear
Lorazepam-diazepam protocol for catatonia in schizophrenia: a 21-case analysis.
    Comprehensive psychiatry, 2013, Volume: 54, Issue:8

    Topics: Anti-Anxiety Agents; Catatonia; Clinical Protocols; Diazepam; Drug Therapy, Combination; Humans; Lor

2013
Lorazepam and diazepam for relieving catatonic features in multiple sclerosis.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, Oct-01, Volume: 31, Issue:7

    Topics: Adult; Catatonia; Diazepam; Drug Therapy, Combination; Electroshock; Female; Humans; Hypnotics and S

2007

Other Studies

29 other studies available for diazepam and Catatonia

ArticleYear
Celiac disease and catatonia: more than a coincidence?
    The Turkish journal of pediatrics, 2023, Volume: 65, Issue:1

    Topics: Adolescent; Amantadine; Biopsy; Catatonia; Celiac Disease; Child; Diazepam; Female; Humans

2023
Etizolam withdrawal catatonia: The first case report.
    Asian journal of psychiatry, 2018, Volume: 37

    Topics: Adult; Catatonia; Diazepam; Electroconvulsive Therapy; Humans; Male; Substance Withdrawal Syndrome;

2018
Relapses and recurrences of catatonia: 30-case analysis and literature review.
    Comprehensive psychiatry, 2016, Volume: 66

    Topics: Adolescent; Adult; Antipsychotic Agents; Bipolar Disorder; Catatonia; Clozapine; Depressive Disorder

2016
Anti-NMDA (a-NMDAR) receptor encephalitis related to acute consumption of metamphetamine: Relevance of differential diagnosis.
    Revista espanola de anestesiologia y reanimacion, 2017, Volume: 64, Issue:3

    Topics: Anti-N-Methyl-D-Aspartate Receptor Encephalitis; Anticonvulsants; Autoantibodies; Benzodiazepines; C

2017
The Lorazepam and Diazepam Protocol for Catatonia Due to General Medical Condition and Substance in Liaison Psychiatry.
    PloS one, 2017, Volume: 12, Issue:1

    Topics: Adult; Catatonia; Diagnostic and Statistical Manual of Mental Disorders; Diazepam; Female; Follow-Up

2017
Impairment of the cortical GABAergic inhibitory system in catatonic stupor: a case report with neuroimaging.
    Epileptic disorders : international epilepsy journal with videotape, 2009, Volume: 11, Issue:2

    Topics: Acute Disease; Adult; Catatonia; Cerebral Cortex; Diazepam; Electroencephalography; Encephalitis; Fl

2009
Lorazepam and diazepam for relieving catatonic features precipitated by initial hemodialysis in a uremic patient: a case report.
    Progress in neuro-psychopharmacology & biological psychiatry, 2010, Mar-17, Volume: 34, Issue:2

    Topics: Adult; Catatonia; Diazepam; Humans; Hypnotics and Sedatives; Lorazepam; Male; Renal Dialysis; Uremia

2010
[Case with difficulty in differentiating between transient neuroleptic malignant syndrome and catatonia after neuroleptic analgesia].
    Masui. The Japanese journal of anesthesiology, 2010, Volume: 59, Issue:2

    Topics: Adolescent; Analgesia; Anesthesia, General; Catatonia; Diagnosis, Differential; Diazepam; Droperidol

2010
[Diazepam-responsive malignant catatonia in a patient with an initial clinical diagnosis of neuroleptic malignant syndrome: a case report].
    Brain and nerve = Shinkei kenkyu no shinpo, 2011, Volume: 63, Issue:5

    Topics: Adult; Biomarkers; Catatonia; Creatine Kinase; Diagnosis, Differential; Diazepam; Humans; Male; Musc

2011
Dexamethasone induced psychosis presenting with catatonic features.
    African journal of psychiatry, 2011, Volume: 14, Issue:4

    Topics: Adult; Antipsychotic Agents; Catatonia; Dexamethasone; Diazepam; Female; Follow-Up Studies; GABA Mod

2011
Benzodiazepines in catatonia associated with systemic lupus erythematosus.
    Psychiatry and clinical neurosciences, 2006, Volume: 60, Issue:6

    Topics: Adult; Anti-Inflammatory Agents; Catatonia; Diazepam; Electroencephalography; Female; GABA Modulator

2006
Maximal response to electroconvulsive therapy for the treatment of catatonic symptoms.
    The journal of ECT, 2007, Volume: 23, Issue:4

    Topics: Administration, Oral; Adult; Aged; Antipsychotic Agents; Catatonia; Diazepam; Dose-Response Relation

2007
Maprotiline hydrochloride associated with a clinical state of catatonic stupor and epileptic encephalogram.
    Journal of clinical psychopharmacology, 1984, Volume: 4, Issue:4

    Topics: Anthracenes; Catatonia; Depressive Disorder; Diazepam; Drug Therapy, Combination; Electroencephalogr

1984
Catatonia mimicking nonconvulsive status epilepticus.
    Epilepsia, 1995, Volume: 36, Issue:9

    Topics: Adult; Benzodiazepines; Bipolar Disorder; Catatonia; Diagnosis, Differential; Diazepam; Electroencep

1995
Benzodiazepines and the psychopathology of catatonia.
    Pharmacopsychiatry, 1994, Volume: 27, Issue:6

    Topics: Adolescent; Adult; Anti-Anxiety Agents; Catatonia; Diazepam; Humans; Lorazepam; Male

1994
Benzodiazepines in the treatment of catatonic syndrome.
    Acta psychiatrica Scandinavica, 1994, Volume: 89, Issue:4

    Topics: Adolescent; Adult; Benzodiazepines; Catatonia; Diazepam; Electroconvulsive Therapy; Female; Humans;

1994
Catatonia: the tension insanity.
    The British journal of psychiatry : the journal of mental science, 1993, Volume: 163

    Topics: Carbamazepine; Catatonia; Diazepam; Female; Humans; Lorazepam; Male

1993
Catatonic syndrome following recovery from neuroleptic malignant syndrome.
    Journal of intellectual disability research : JIDR, 1995, Volume: 39 ( Pt 5)

    Topics: Anti-Anxiety Agents; Antipsychotic Agents; Catatonia; Chlorpromazine; Diazepam; Dose-Response Relati

1995
Possibility of LSD-induced catatonia.
    The Australian and New Zealand journal of psychiatry, 1995, Volume: 29, Issue:4

    Topics: Anti-Anxiety Agents; Catatonia; Diazepam; Dose-Response Relationship, Drug; Drug Administration Sche

1995
Catatonia after benzodiazepine withdrawal.
    Journal of clinical psychopharmacology, 1996, Volume: 16, Issue:4

    Topics: Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Catatonia; Clonazepam; Diazepam; Female; H

1996
Diazepam-responsive neuroleptic malignant syndrome: a diagnostic subtype?
    The American journal of psychiatry, 1997, Volume: 154, Issue:6

    Topics: Antipsychotic Agents; Catatonia; Diazepam; Female; Humans; Infusions, Intravenous; Middle Aged; Neur

1997
The treatment of stupor associated with MRI evidence of cerebrovascular disease.
    International journal of geriatric psychiatry, 1997, Volume: 12, Issue:8

    Topics: Aged; Anticonvulsants; Antidepressive Agents; Carbamazepine; Catatonia; Cerebrovascular Disorders; C

1997
Neuropharmacological interaction between ketamine, and physostigmine, diazepam or propranolol.
    Proceedings of the Western Pharmacology Society, 1976, Volume: 19

    Topics: Animals; Catatonia; Cats; Cortical Synchronization; Diazepam; Drug Interactions; Electrodes, Implant

1976
Catatonia and the neuroleptic malignant syndrome--a single entity?
    The British journal of psychiatry : the journal of mental science, 1992, Volume: 161

    Topics: Adult; Catatonia; Chlorpromazine; Diazepam; Female; Follow-Up Studies; Humans; Neuroleptic Malignant

1992
Abreaction before ECT?
    The British journal of psychiatry : the journal of mental science, 1991, Volume: 159

    Topics: Abreaction; Amobarbital; Catatonia; Diazepam; Electroconvulsive Therapy; Humans; Interview, Psycholo

1991
Treatment of lethal catatonia with electroconvulsive therapy and dantrolene sodium: a case report.
    Acta psychiatrica Scandinavica, 1990, Volume: 82, Issue:1

    Topics: Adolescent; Catatonia; Combined Modality Therapy; Dantrolene; Diazepam; Electroconvulsive Therapy; H

1990
Benzodiazepines for catatonic symptoms, stupor, and mutism.
    Pharmacopsychiatry, 1988, Volume: 21, Issue:6

    Topics: Anti-Anxiety Agents; Benzodiazepines; Catatonia; Depressive Disorder; Diazepam; Female; Flumazenil;

1988
Lucid intervals in catatonia: a neuropsychiatric snare for the unwary.
    The British journal of psychiatry : the journal of mental science, 1987, Volume: 151

    Topics: Adult; Catatonia; Diazepam; Female; Humans

1987
[Management of chronic schizophrenias using Valium].
    Schweizer Archiv fur Neurologie, Neurochirurgie und Psychiatrie = Archives suisses de neurologie, neurochirurgie et de psychiatrie, 1969, Volume: 104, Issue:1

    Topics: Aged; Catatonia; Chronic Disease; Diazepam; Drug Synergism; Female; Humans; Paranoid Disorders; Schi

1969