Page last updated: 2024-10-25

diazepam and Cardiovascular Diseases

diazepam has been researched along with Cardiovascular Diseases in 32 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.

Research Excerpts

ExcerptRelevanceReference
"Mianserin is a tetracyclic compound advocated for the treatment of depressive illness and depression associated with anxiety."4.75Mianserin: a review of its pharmacological properties and therapeutic efficacy in depressive illness. ( Avery, GS; Brogden, RN; Heel, RC; Speight, TM, 1978)
"The high utilization of diazepam in pregnancy that is not supported by professional guidelines is an issue of serious concern."3.76The effects of benzodiazepines in pregnancy. ( Culig, J; Eric, M; Leppée, M; Sijanovic, S, 2010)
"A male patient with no risk factors for ischemic heart disease, presented to our emergency department with agitation and chest pain characteristic of ischemia following the ingestion of two units of "Head Candy."1.35Cardiovascular toxicity associated with recreational use of diphenylprolinol (diphenyl-2-pyrrolidinemethanol [D2PM]). ( Button, J; Dargan, P; Holt, D; Lidder, S; Ramsey, J; Sexton, M; Wood, D, 2008)
" Clinicians are encouraged to report possible adverse drug reactions to the National Registry of Drug-Induced Ocular Side Effects, which has been moved to the Department of Ophthalmology, University of Oregon Health Sciences Center, Portland, OR 97201."1.26Interim report: National Registry of Possible Drug-Induced Ocular Side Effects. ( Fraunfelder, FT, 1979)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199029 (90.63)18.7374
1990's0 (0.00)18.2507
2000's1 (3.13)29.6817
2010's2 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-Moreno, M1
Saborido, C1
Teira, D1
Lidder, S1
Dargan, P1
Sexton, M1
Button, J1
Ramsey, J1
Holt, D1
Wood, D1
Leppée, M1
Culig, J1
Eric, M1
Sijanovic, S1
Hanak, T3
Katon, RM1
Pinder, RM1
Fink, M1
Follmer, CH1
Lum, BK1
Luyckx, A1
Van Cauwenberge, H1
Brogden, RN1
Heel, RC1
Speight, TM1
Avery, GS1
Rollin, P1
Antaki, AJ1
Navrátilová, A1
Varmuzková, J1
Cundrle, I1
Fraunfelder, FT1
Nixon, PG1
Raĭskiĭ, VA1
Rozonov, IuB1
Chichkanov, GG1
Saissy, JM1
Gohard, R1
Diatta, B1
Kempf, J1
Raux, O1
Gordon, M1
Schröder, R1
Newcomb, GM1
Donhardt, A1
Schultz, R1
Lingjaerde, O1
Heyden, S1
Wild, R1
Escher, M1
Bruderer, E1
Metzler, B1
Hofmann, KW1
Manach, J1
Sögtrop, HH1
Olthoff, D1
Blätterlein, I1
Müller, L1
Aellig, WH1
O'Neil, R1
Laurence, DR1
Verrill, PJ1
Harp, JR1
Chiti, E1
Delius, L1
Fischer, M1
McClish, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Maternal-Fetal Monitoring of Patients With Rheumatic Heart Disease During Dental Procedure Under Local Anesthesia[NCT00482573]Phase 131 participants (Actual)Interventional2004-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for diazepam and Cardiovascular Diseases

ArticleYear
Complications of upper gastrointestinal endoscopy in the gastrointestinal bleeder.
    Digestive diseases and sciences, 1981, Volume: 26, Issue:7 Suppl

    Topics: Adult; Aged; Anesthesia, Local; Cardiovascular Diseases; Diazepam; Electrocardiography; Endoscopy; E

1981
Mianserin.
    Modern problems of pharmacopsychiatry, 1982, Volume: 18

    Topics: Animals; Antidepressive Agents, Tricyclic; Cardiovascular Diseases; Central Nervous System; Depressi

1982
Mianserin: a review of its pharmacological properties and therapeutic efficacy in depressive illness.
    Drugs, 1978, Volume: 16, Issue:4

    Topics: Amitriptyline; Animals; Antidepressive Agents; Carbohydrate Metabolism; Cardiovascular Diseases; Dep

1978
[Poisoning due to tricyclic antidepressants in children and adolescents].
    Canadian Medical Association journal, 1979, Apr-21, Volume: 120, Issue:8

    Topics: Adolescent; Amitriptyline; Antidepressive Agents, Tricyclic; Cardiovascular Diseases; Central Nervou

1979
Contraindications to the use of catecholamine vasoconstrictors in dental local analgesics.
    The New Zealand dental journal, 1973, Volume: 69, Issue:315

    Topics: Anesthesia, Dental; Anesthesia, General; Anesthesia, Local; Antidepressive Agents; Antihypertensive

1973
[Dipotassium chlorazepate. Clinical reports on a new anxiolytic].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:1

    Topics: Adult; Aged; Alcoholism; Automobile Driving; Cardiovascular Diseases; Diabetes Mellitus; Diazepam; D

1970

Trials

3 trials available for diazepam and Cardiovascular Diseases

ArticleYear
[Treatment of functional sympathicotonic circulatory regulation disorders with metoprolol in depot form. Cross-over double-blind study with diazepam and Beloc-Duriles].
    Die Medizinische Welt, 1983, Jun-24, Volume: 34, Issue:25-26

    Topics: Adrenergic beta-Antagonists; Adult; Cardiovascular Diseases; Delayed-Action Preparations; Diazepam;

1983
[Double-blind cross-over study on alprenolol and diazepam in the treatment of functional sympathetic cardiac and circulatory disorders].
    Die Medizinische Welt, 1977, Sep-23, Volume: 28, Issue:38

    Topics: Adult; Alprenolol; Cardiovascular Diseases; Clinical Trials as Topic; Diazepam; Double-Blind Method;

1977
[Double-blind cross-over study with alprenolol and diazepam in the treatment of functional sympathicotonic cardiovascular diseases].
    Die Medizinische Welt, 1977, Dec-30, Volume: 28, Issue:51-52

    Topics: Alprenolol; Cardiovascular Diseases; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female

1977

Other Studies

23 other studies available for diazepam and Cardiovascular Diseases

ArticleYear
Disease-mongering through clinical trials.
    Studies in history and philosophy of biological and biomedical sciences, 2015, Volume: 51

    Topics: Anti-Anxiety Agents; Anxiety; Biomedical Research; Cardiovascular Diseases; Cholesterol; Diazepam; D

2015
Cardiovascular toxicity associated with recreational use of diphenylprolinol (diphenyl-2-pyrrolidinemethanol [D2PM]).
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2008, Volume: 4, Issue:3

    Topics: Adult; Aporphines; Biphenyl Compounds; Blood Pressure; Cardiovascular Diseases; Diazepam; Heart Rate

2008
The effects of benzodiazepines in pregnancy.
    Acta neurologica Belgica, 2010, Volume: 110, Issue:2

    Topics: Abnormalities, Drug-Induced; Anti-Anxiety Agents; Anxiety; Cardiovascular Diseases; Diazepam; Female

2010
Protective action of diazepam and of sympathomimetic amines against amitryptyline-induced toxicity.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 222, Issue:2

    Topics: Amitriptyline; Anesthesia; Animals; Cardiovascular Diseases; Cats; Diazepam; Female; Male; Myocardia

1982
[Therapeutic news of 1975].
    Revue medicale de Liege, 1976, Apr-15, Volume: 31, Issue:8

    Topics: Bismuth; Cardiovascular Diseases; Diazepam; Drug Therapy; Endocrine System Diseases; Gastrointestina

1976
[Intravenous anesthetics as an introduction of general anesthesia in patients with complicating disease of the respiratory and circulatory systems].
    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti, 1979, Volume: 58, Issue:1

    Topics: Alfaxalone Alfadolone Mixture; Anesthesia, Intravenous; Cardiovascular Diseases; Diazepam; Flunitraz

1979
Interim report: National Registry of Possible Drug-Induced Ocular Side Effects.
    Ophthalmology, 1979, Volume: 86, Issue:1

    Topics: Aged; Anesthetics, Local; Carbonic Anhydrase Inhibitors; Cardiovascular Diseases; Diazepam; Dietary

1979
The human function curve. With special reference to cardiovascular disorders: part I.
    The Practitioner, 1976, Volume: 217, Issue:1301

    Topics: Affective Symptoms; Aggression; Arousal; Cardiovascular Diseases; Diazepam; Environment; Fatigue; Hu

1976
[Comparative findings concerning the effect of elenium and seduxen on the cardiovascular system].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1976, Volume: 76, Issue:2

    Topics: Adolescent; Adult; Bradycardia; Cardiovascular Diseases; Chlordiazepoxide; Diazepam; Female; Humans;

1976
[Role of single-therapy diazepam in severe poisonings by chloroquine].
    Presse medicale (Paris, France : 1983), 1989, Dec-09, Volume: 18, Issue:41

    Topics: Adolescent; Adult; Cardiovascular Diseases; Chloroquine; Diazepam; Female; Humans; Male

1989
Differential diagnosis of weakness--a common geriatric symptom.
    Geriatrics, 1986, Volume: 41, Issue:4

    Topics: Aged; Alcoholism; Arthritis; Cardiovascular Diseases; Depression; Diabetes Complications; Diagnosis,

1986
[Drug therapy of hemodynamic complications in acute myocardial infarct].
    Der Internist, 1972, Volume: 13, Issue:9

    Topics: Aged; Analgesia; Anti-Arrhythmia Agents; Blood Volume; Bradycardia; Cardiovascular Diseases; Diazepa

1972
[Therapy of acute poisoning with hypnotic and tranquilizer poisoning].
    Deutsche medizinische Wochenschrift (1946), 1972, Nov-10, Volume: 97, Issue:45

    Topics: Blood Circulation; Cardiovascular Diseases; Diazepam; Gastric Lavage; Humans; Hypnotics and Sedative

1972
[A new, particular syndrome induced by large doses of diazepam?].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Mar-30, Volume: 93, Issue:9

    Topics: Adult; Aged; Cardiovascular Diseases; Depression; Diazepam; Dose-Response Relationship, Drug; Humans

1973
Letter: Coping with nose-bleeds.
    British medical journal, 1974, Apr-13, Volume: 2, Issue:5910

    Topics: Adult; Aged; Bandages; Cardiovascular Diseases; Cautery; Child; Cold Temperature; Diazepam; Epistaxi

1974
[Smoking habits and smoking withdrawal in Swiss men].
    Schweizerische medizinische Wochenschrift, 1974, Jun-01, Volume: 104, Issue:22

    Topics: Adolescent; Adult; Age Factors; Aged; Blood Pressure; Body Weight; Bronchitis; Cardiovascular Diseas

1974
[Studies on the problem of anesthesia control in patients with heart diseases].
    Das Deutsche Gesundheitswesen, 1971, May-20, Volume: 26, Issue:21

    Topics: Adult; Anesthesia; Anesthetics; Barbiturates; Blood Pressure; Cardiovascular Diseases; Diazepam; Fem

1971
Cardiac effects of adrenaline and felypressin as vasoconstrictors in local anaesthesia for oral surgery under diazepam sedation.
    British journal of anaesthesia, 1970, Volume: 42, Issue:2

    Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Blood Pressure; Cardiovascular Diseases; Diazepam; Ele

1970
Diazepam induction in the poor risk patient.
    Journal of the Tennessee Medical Association, 1970, Volume: 63, Issue:9

    Topics: Aged; Anesthesia, Intravenous; Cardiovascular Diseases; Diazepam; Female; Humans; Male; Middle Aged

1970
[The psychotropic drugs in internal medicine: action of a new benzodiazepine (Nobrium)].
    Il Policlinico. Sezione pratica, 1970, Jul-13, Volume: 77, Issue:28

    Topics: Adult; Aged; Asthma; Biliary Tract Diseases; Cardiovascular Diseases; Diazepam; Female; Gastrointest

1970
[Psychovegetative syndrome and its treatment].
    Wiener medizinische Wochenschrift (1946), 1971, Mar-06, Volume: 121, Issue:10

    Topics: Aged; Amitriptyline; Behavior Therapy; Cardiovascular Diseases; Chlordiazepoxide; Diazepam; Exercise

1971
[Relaxation--autonomic stabilization--sleep promotion--muscle relaxation].
    Der Landarzt, 1967, Sep-30, Volume: 43, Issue:27

    Topics: Cardiovascular Diseases; Central Nervous System Diseases; Diazepam; Dysautonomia, Familial; Female;

1967
Diazepam as an intravenous induction agent for general anaesthesia.
    Canadian Anaesthetists' Society journal, 1966, Volume: 13, Issue:6

    Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Cardiovascular Diseases; C

1966