diazepam has been researched along with Cacosmia in 5 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A Phase 3 open-label safety study (NCT02721069) evaluated long-term safety of diazepam nasal spray (Valtoco) in patients with epilepsy and frequent seizure clusters." | 9.41 | Final results from a Phase 3, long-term, open-label, repeat-dose safety study of diazepam nasal spray for seizure clusters in patients with epilepsy. ( Biton, V; Carrazana, E; Cascino, GD; Desai, J; Dlugos, D; Hogan, RE; Liow, K; Mauney, W; Miller, I; Rabinowicz, AL; Segal, EB; Sperling, MR; Tarquinio, D; Vazquez, B; Wheless, JW, 2021) |
| "A Phase 3 open-label safety study (NCT02721069) evaluated long-term safety of diazepam nasal spray (Valtoco) in patients with epilepsy and frequent seizure clusters." | 5.41 | Final results from a Phase 3, long-term, open-label, repeat-dose safety study of diazepam nasal spray for seizure clusters in patients with epilepsy. ( Biton, V; Carrazana, E; Cascino, GD; Desai, J; Dlugos, D; Hogan, RE; Liow, K; Mauney, W; Miller, I; Rabinowicz, AL; Segal, EB; Sperling, MR; Tarquinio, D; Vazquez, B; Wheless, JW, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wheless, JW | 1 |
| Miller, I | 1 |
| Hogan, RE | 1 |
| Dlugos, D | 1 |
| Biton, V | 1 |
| Cascino, GD | 1 |
| Sperling, MR | 1 |
| Liow, K | 1 |
| Vazquez, B | 1 |
| Segal, EB | 1 |
| Tarquinio, D | 1 |
| Mauney, W | 1 |
| Desai, J | 1 |
| Rabinowicz, AL | 1 |
| Carrazana, E | 1 |
| Chioca, LR | 1 |
| Antunes, VD | 1 |
| Ferro, MM | 1 |
| Losso, EM | 1 |
| Andreatini, R | 1 |
| MacRae, M | 1 |
| Kenkel, WM | 1 |
| Kentner, AC | 1 |
| Saitoh, A | 1 |
| Hirose, N | 1 |
| Yamada, M | 2 |
| Nozaki, C | 1 |
| Oka, T | 1 |
| Kamei, J | 1 |
| Sokolic, L | 1 |
| McGregor, IS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A 12-Month Open-Label, Repeat-Dose Safety Study of NRL-1 in Epilepsy Subjects (DIAZ.001.05)[NCT02721069] | Phase 3 | 175 participants (Actual) | Interventional | 2016-04-11 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Assess the number of participants who received at least one dose of NRL-1 (Valtoco) during the study and comprised the safety population. (NCT02721069)
Timeframe: 12 months
| Intervention | Participants (Count of Participants) |
|---|---|
| NRL-1 5mg | 9 |
| NRL-1 10mg | 54 |
| NRL-1 15 mg | 46 |
| NRL-1 20mg | 54 |
1 trial available for diazepam and Cacosmia
| Article | Year |
|---|---|
Final results from a Phase 3, long-term, open-label, repeat-dose safety study of diazepam nasal spray for seizure clusters in patients with epilepsy.
Topics: Administration, Intranasal; Adolescent; Adult; Aged; Anticonvulsants; Brain Damage, Chronic; Child; | 2021 |
4 other studies available for diazepam and Cacosmia
| Article | Year |
|---|---|
Anosmia does not impair the anxiolytic-like effect of lavender essential oil inhalation in mice.
Topics: Administration, Inhalation; Analysis of Variance; Animals; Anti-Anxiety Agents; Behavior, Animal; Di | 2013 |
Social rejection following neonatal inflammation is mediated by olfactory scent cues.
Topics: Administration, Intranasal; Animals; Animals, Newborn; Anti-Anxiety Agents; Behavior, Animal; Cues; | 2015 |
Changes in emotional behavior of mice in the hole-board test after olfactory bulbectomy.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzamides; | 2006 |
Benzodiazepines impair the acquisition and reversal of olfactory go/no-go discriminations in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Benzodiazepines; Choice Behavior; Diazepam; Discrim | 2007 |