Page last updated: 2024-10-25

diazepam and Breast Cancer

diazepam has been researched along with Breast Cancer in 22 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Research Excerpts

ExcerptRelevanceReference
"The relation of breast cancer to diazepam use was evaluated in a case-control study of 1236 women with breast cancer and 728 control subjects with other malignancies."9.05Diazepam and the risk of breast cancer. ( Helmrich, SP; Kaufman, DW; Levy, M; Miettinen, OS; Rosenberg, L; Schottenfeld, D; Shapiro, S; Slone, D; Stolley, PD, 1982)
"The relation between diazepam use and breast cancer was explored in two case-control studies."7.68Diazepam use in relation to breast cancer: results from two case-control studies. ( Clarke, EA; Kaufman, DW; Miller, DR; Palmer, JR; Rosenberg, L; Shapiro, S; Stolley, PD; Warshauer, ME; Werler, MM, 1990)
"The relationship between diazepam and breast cancer was evaluated using data from a case-control study of breast cancer, in which 1075 cases and 1146 controls who were participants in a breast cancer screening program were interviewed."7.67Diazepam use and progression of breast cancer. ( Brinton, LA; Fraumeni, JF; Hoover, R; Kleinerman, RA, 1984)
" The aim of this study was to prospectively evaluate the effect of patient preparation using a single oral dose of diazepam and controlled indoor temperature to prevent (18)F-FDG uptake in BAT in breast cancer patients referred for monitoring of therapy response with (18)F-FDG PET."5.14Prevention of brown adipose tissue activation in 18F-FDG PET/CT of breast cancer patients receiving neoadjuvant systemic therapy. ( Aukema, TS; Hoefnagel, CA; Valdés Olmos, RA; Vogel, WV, 2010)
"To investigate the effects of preanesthetic oral clonidine on total propofol requirement for uniform minor surgery (breast conservative surgery: breast cancer removal with axillary lymph node dissection), and to compare the action of clonidine with that of preanesthetic oral diazepam, a commonly used benzodiazepine."5.08The effects of preanesthetic oral clonidine on total requirement of propofol for general anesthesia. ( Imai, Y; Kagawa, K; Kirita, T; Kishi, Y; Kita, T; Mammoto, T; Murakami, K; Sakai, T; Sugimura, M, 1998)
"The relation of breast cancer to diazepam use was evaluated in a case-control study of 1236 women with breast cancer and 728 control subjects with other malignancies."5.05Diazepam and the risk of breast cancer. ( Helmrich, SP; Kaufman, DW; Levy, M; Miettinen, OS; Rosenberg, L; Schottenfeld, D; Shapiro, S; Slone, D; Stolley, PD, 1982)
"The relation between diazepam use and breast cancer was explored in two case-control studies."3.68Diazepam use in relation to breast cancer: results from two case-control studies. ( Clarke, EA; Kaufman, DW; Miller, DR; Palmer, JR; Rosenberg, L; Shapiro, S; Stolley, PD; Warshauer, ME; Werler, MM, 1990)
"The relationship between diazepam and breast cancer was evaluated using data from a case-control study of breast cancer, in which 1075 cases and 1146 controls who were participants in a breast cancer screening program were interviewed."3.67Diazepam use and progression of breast cancer. ( Brinton, LA; Fraumeni, JF; Hoover, R; Kleinerman, RA, 1984)
"Diazepam was able to displace [3H]Ro5-4864 from binding only at high concentrations (>1 microM), while ODN did not compete for PBR binding."1.30Specific binding of benzodiazepines to human breast cancer cell lines. ( Beinlich, A; Kaufmann, M; Kuhl, H; Strohmeier, R, 1999)
"Psychotropic agents can promote tumors and inhibit neoplastic cell growth."1.27[Psychopharmaceuticals and cancer. Modification of tumor growth by psychoactive drugs]. ( Jäger, H, 1984)
"Diazepam has the characteristics of a tumour promoter in a number of in vitro systems."1.26The possible effect of diazepam on cancer development and growth. ( Horrobin, DF; Trosko, JE, 1981)
"This report is an example of tumor metastasis to the temporomandibular joint and its effect on pain, restriction of jaw movement, and the subsequent inability of the patient to function normally."1.25Myofascial pain dysfunction syndrome involving tumor metastasis. Case report. ( Butler, JH, 1975)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199012 (54.55)18.7374
1990's6 (27.27)18.2507
2000's0 (0.00)29.6817
2010's3 (13.64)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Germain, AR1
Carmody, LC1
Nag, PP1
Morgan, B1
Verplank, L1
Fernandez, C1
Donckele, E1
Feng, Y1
Perez, JR1
Dandapani, S1
Palmer, M1
Lander, ES1
Gupta, PB1
Schreiber, SL1
Munoz, B1
Hamed, MM1
Darwish, SS1
Herrmann, J1
Abadi, AH1
Engel, M1
Dhanani, LY1
Totton, RR1
Jara-Quijada, E1
Pérez-Won, M1
Tabilo-Munizaga, G1
Lemus-Mondaca, R1
González-Cavieres, L1
Palma-Acevedo, A1
Herrera-Lavados, C1
Milovanovic, S1
Grzegorczyk, A1
Świątek, Ł1
Grzęda, A1
Dębczak, A1
Tyskiewicz, K1
Konkol, M1
Li, Y2
Chang, P1
Sankaran, S1
Jang, H1
Nie, Y1
Zeng, A1
Hussain, S1
Wu, JY1
Chen, X2
Shi, L2
Senapati, A1
Chetri, BK1
Mitra, S1
Shelke, RG1
Rangan, L1
Chauhan, AS1
Tiwari, M1
Indoliya, Y1
Mishra, SK1
Lavania, UC1
Chauhan, PS1
Chakrabarty, D1
Tripathi, RD1
Akaputra, R1
Hatta, M1
Massi, MN1
Djaharuddin, I1
Bukhari, A1
Aminuddin, A1
Santoso, A1
Natzir, R1
Bahar, B1
Fachri, M1
Farsida, F1
Fathimah, A1
Ubaidah, FM1
Sridiana, E1
Dwiyanti, R1
Syukri, A1
Junita, AR1
Febrianti, A1
Primaguna, MR1
Azhar, A1
Rajaure, YS1
Thapa, B1
Budhathoki, L1
Rana, SR1
Khadka, M1
Batchu, UR1
Surapaneni, JR1
Cheemalamarri, C1
Mandava, K1
Puvvada, N1
Shetty, PR1
Mv, S1
Ranjbarian, P1
Goudarzi, F1
Akya, A1
Heidarinia, H1
Farasat, A1
Rostamian, M1
Suri, K1
Rajput, N1
Sharma, P1
Omble, AD1
Kulkarni, K1
Gahlay, GK1
Fernandez Garcia, E1
Paudel, U1
Noji, MC1
Bowman, CE1
Rustgi, AK1
Pitarresi, JR1
Wellen, KE1
Arany, Z1
Weissenrieder, JS1
Foskett, JK1
Lee, MS1
Han, HJ1
Choi, TI1
Lee, KH1
Baasankhuu, A1
Kim, HT1
Kim, CH1
Redd, PS1
Payero, L1
Gilbert, DM1
Page, CA1
King, R1
McAssey, EV1
Bodie, D1
Diaz, S1
Hancock, CN1
Lee, HS1
Jung, S1
Lee, SW1
Kim, YT1
Lee, J1
Ren, T1
Yu, Z1
Yu, H1
Deng, K1
Wang, Z1
Li, X1
Wang, H1
Wang, L2
Xu, Y1
Lascano, J1
Riley, L1
Khodayari, N1
Brantly, M1
Gupta, R1
Pradhan, J1
Haldar, A1
Murapaka, C1
Chandra Mondal, P1
Gao, R1
Dai, TY1
Meng, Z1
Sun, XF1
Liu, DX1
Shi, MM1
Li, HR1
Kang, X1
Bi, B1
Zhang, YT1
Xu, TW1
Yan, JM1
Jiang, Q1
Helmchen, G1
Guo, H1
Xiang, W1
Fang, Y1
Li, J4
Lin, Y1
An, X1
Jiang, D1
Cao, Q1
Xu, F1
Shiigi, H1
Wang, W1
Chen, Z1
Akosman, I1
Kumar, N1
Mortenson, R1
Lans, A1
De La Garza Ramos, R1
Eleswarapu, A1
Yassari, R1
Fourman, MS1
Jana, S1
Evans, EGB1
Jang, HS1
Zhang, S2
Zhang, H1
Rajca, A1
Gordon, SE1
Zagotta, WN1
Stoll, S1
Mehl, RA1
Miller, S1
Lee, DA1
Muhimpundu, S1
Maxwell, CA1
Liu, Z1
Shen, F1
Tong, Q1
Tang, M1
Peng, M1
Jiao, Z1
Jiang, Y1
Ao, L1
Fu, W1
Lv, X1
Jiang, G1
Hou, L1
Tu, WC1
McManamen, AM1
Su, X1
Jeacopello, I1
Takezawa, MG1
Hieber, DL1
Hassan, GW1
Lee, UN1
Anana, EV1
Locknane, MP1
Stephenson, MW1
Shinkawa, VAM1
Wald, ER1
DeMuri, GP1
Adams, KN1
Berthier, E1
Thongpang, S1
Theberge, AB1
Jiang, L1
Li, Z1
Dong, Q1
Rong, X1
Dong, G1
Huang, J1
Liang, Y1
Sun, S1
Zhang, R1
Miao, Z1
Senju, C1
Nakazawa, Y1
Oso, T1
Shimada, M1
Kato, K1
Matsuse, M1
Tsujimoto, M1
Masaki, T1
Miyazaki, Y1
Fukushima, S1
Tateishi, S1
Utani, A1
Murota, H1
Tanaka, K1
Mitsutake, N1
Moriwaki, S1
Nishigori, C1
Ogi, T1
Liu, C1
Zhang, X1
Wang, B1
Luo, Z1
Qian, D1
Liu, J1
Waterhouse, GIN1
Barbosa, M1
Marques-Sá, J1
Carvalho, C1
Fernandes, V1
Grilli, D1
Smetana, V1
Ahmed, SJ1
Shtender, V1
Pani, M1
Manfrinetti, P1
Mudring, AV1
Kuang, Y1
Yang, D1
Gai, S1
He, F1
An, B1
Yang, P1
Notini, L1
Schulz, K1
Kubeneck, LJ1
Grigg, ARC1
Rothwell, KA1
Fantappiè, G1
ThomasArrigo, LK1
Kretzschmar, R1
Siswanto, FM1
Okukawa, K1
Tamura, A1
Oguro, A1
Imaoka, S1
Kim, CG1
Jung, M1
Kim, HS1
Lee, CK1
Jeung, HC1
Koo, DH1
Bae, WK1
Zang, DY1
Kim, BJ1
Kim, H1
Yun, UJ1
Che, J1
Park, S1
Kim, TS1
Kwon, WS1
Park, J1
Cho, SW1
Nam, CM1
Chung, HC1
Rha, SY1
Colombo, N1
Van Gorp, T1
Matulonis, UA1
Oaknin, A1
Grisham, RN1
Fleming, GF1
Olawaiye, AB1
Nguyen, DD1
Greenstein, AE1
Custodio, JM1
Pashova, HI1
Tudor, IC1
Lorusso, D1
Zhou, F1
Jiang, Z1
Liang, H1
Ru, S1
Bettiol, AA1
Gao, W1
Lipsyc-Sharf, M1
Jain, E1
Collins, LC1
Rosenberg, SM1
Ruddy, KJ1
Tamimi, RM1
Schapira, L1
Come, SE1
Peppercorn, JM1
Borges, VF1
Warner, E1
Snow, C1
Krop, IE1
Kim, D1
Weiss, J1
Zanudo, JGT1
Partridge, AH1
Wagle, N1
Waks, AG1
Moskowitz, A1
Berg, KM1
Grossestreuer, AV1
Balaji, L1
Liu, X1
Cocchi, MN1
Chase, M1
Gong, MN1
Gong, J1
Parikh, SM1
Ngo, L1
Berlin, N1
Donnino, MW1
Zhou, Y1
Chen, Q1
Zhong, S1
Liu, H1
Koh, K1
Chen, H1
He, J1
Chen, J1
Liu, S1
Lin, L1
Zhang, Y1
Xiao, S1
Cao, S1
Yan, B2
Deng, J1
Gu, J1
Tao, Y1
Huang, C1
Lai, C1
Yong, Q1
Shen, Y1
Gong, Z1
Cao, J1
Mao, W1
Yao, Y1
Zhao, J1
Li, Q1
Liu, K1
Liu, B1
Feng, S1
Chandran, V1
Kunjan, C1
Veerapandian, V1
Kannan, R1
Zhang, T1
von Gunten, U1
Caruso, FR1
Goulart, CDL1
Jr, JCB1
de Oliveira, CR1
Mendes, RG1
Arena, R1
Borghi-Silva, A1
Carrasco-Nuñes, N1
Romano, M1
Cabeza, M1
Jiang, B1
Chen, D1
Zhao, C1
Ma, Y1
Yang, W1
Shen, X1
Satheeshkumar, K1
Saravanakumar, P1
Kalavathi, A1
Vennila, KN1
Elango, KP1
Mues Genannt Koers, L1
Prevost, D1
Paulssen, E1
Hoehr, C1
Ulhassan, Z1
Yang, S1
He, D1
Khan, AR1
Salam, A1
Azhar, W1
Muhammad, S1
Ali, S1
Hamid, Y1
Khan, I1
Sheteiwy, MS1
Zhou, W1
Wang, X1
Xie, Q1
Wang, Y1
Lü, H1
Fu, M1
Wang, D1
Aukema, TS1
Vogel, WV1
Hoefnagel, CA1
Valdés Olmos, RA1
Kleinerman, RA2
Rinton, LA1
Hoover, R2
Fraumeni, JF2
Horrobin, DF3
Kaufman, DW2
Shapiro, S2
Slone, D1
Rosenberg, L2
Helmrich, SP1
Miettinen, OS1
Stolley, PD2
Levy, M1
Schottenfeld, D1
Jäger, H1
Sporny, S1
Brinton, LA1
Hendel, J1
Elsass, P1
Sørensen, KH1
Møller, IW1
Hvidberg, EF1
Hansen, T1
Trosko, JE1
Zeller, WJ1
Ortega, F1
Carreras, JL1
Maldonado, A1
Pérez-Castejón, MJ1
Montz, R1
Gorospe, E1
Ruiz, JA1
Nieto, C1
Imai, Y1
Mammoto, T1
Murakami, K1
Kita, T1
Sakai, T1
Kagawa, K1
Kirita, T1
Sugimura, M1
Kishi, Y1
Niles, LP1
Wang, J1
Beinlich, A1
Strohmeier, R1
Kaufmann, M1
Kuhl, H1
Ghayur, T1
Karmali, RA1
Bratseva, VL1
Butler, JH1
Werler, MM1
Palmer, JR1
Warshauer, ME1
Clarke, EA1
Miller, DR1
Friedman, GD1
Selby, JV1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Remimazolam Tosilate for General Anesthesia on Prognosis After Bladder Cancer Surgery: a Randomized Controlled Trial[NCT04532606]Phase 41,128 participants (Anticipated)Interventional2021-02-05Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for diazepam and Breast Cancer

ArticleYear
[Diazepam and neoplasms].
    Przeglad lekarski, 1984, Volume: 41, Issue:10

    Topics: Animals; Breast Neoplasms; Cocarcinogenesis; Diazepam; Female; Humans; Leukemia L1210; Liver Neoplas

1984

Trials

5 trials available for diazepam and Breast Cancer

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Sexuality research & social policy : journal of NSRC : SR & SP, 2023, Apr-05

    Topics: Acute Kidney Injury; Adult; Aged; Albumins; Alloys; Amides; Amino Acids; Animals; Antineoplastic Com

2023
Prevention of brown adipose tissue activation in 18F-FDG PET/CT of breast cancer patients receiving neoadjuvant systemic therapy.
    Journal of nuclear medicine technology, 2010, Volume: 38, Issue:1

    Topics: Adipose Tissue, Brown; Administration, Oral; Adult; Aged; Aged, 80 and over; Biological Transport; B

2010
Diazepam and the risk of breast cancer.
    Lancet (London, England), 1982, Mar-06, Volume: 1, Issue:8271

    Topics: Adult; Animals; Breast Neoplasms; Clinical Trials as Topic; Diazepam; Female; Humans; Menopause; Mid

1982
Anxiety and sedation during a stressful situation after single dose of diazepam versus N-desmethyldiazepam--a controlled trial.
    Psychopharmacology, 1980, Volume: 70, Issue:3

    Topics: Adult; Anxiety; Breast Neoplasms; Diazepam; Double-Blind Method; Drug Evaluation; Emotions; Female;

1980
The effects of preanesthetic oral clonidine on total requirement of propofol for general anesthesia.
    Journal of clinical anesthesia, 1998, Volume: 10, Issue:8

    Topics: Administration, Oral; Adult; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous;

1998

Other Studies

16 other studies available for diazepam and Breast Cancer

ArticleYear
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
    Bioorganic & medicinal chemistry letters, 2013, Mar-15, Volume: 23, Issue:6

    Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neopla

2013
First Bispecific Inhibitors of the Epidermal Growth Factor Receptor Kinase and the NF-κB Activity As Novel Anticancer Agents.
    Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7

    Topics: Animals; Antineoplastic Agents; Breast; Breast Neoplasms; Cell Line, Tumor; ErbB Receptors; Female;

2017
Diazepam and breast cancer.
    Lancet (London, England), 1981, May-23, Volume: 1, Issue:8230

    Topics: Breast Neoplasms; Diazepam; Female; Humans; Risk

1981
Diazepam and breast cancer.
    Lancet (London, England), 1981, Jun-13, Volume: 1, Issue:8233

    Topics: Breast Neoplasms; Diazepam; Female; Humans; Time Factors

1981
[Psychopharmaceuticals and cancer. Modification of tumor growth by psychoactive drugs].
    Fortschritte der Medizin, 1984, Feb-23, Volume: 102, Issue:8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Antipsychotic Agents; Breast Neoplasms; Com

1984
Diazepam use and progression of breast cancer.
    Cancer research, 1984, Volume: 44, Issue:3

    Topics: Breast Neoplasms; Diazepam; Female; Humans; Lymphatic Metastasis; Neoplasm Invasiveness

1984
The possible effect of diazepam on cancer development and growth.
    Medical hypotheses, 1981, Volume: 7, Issue:1

    Topics: Animals; Breast Neoplasms; Cocarcinogenesis; Diazepam; Female; Humans; Mammary Neoplasms, Experiment

1981
[Tumor stimulation by diazepam?].
    Deutsche medizinische Wochenschrift (1946), 1981, Oct-16, Volume: 106, Issue:42

    Topics: Breast Neoplasms; Diazepam; Female; Humans; Male; Prostatic Neoplasms

1981
[Muscle uptake of 18FDG in positron emission tomography].
    Revista espanola de medicina nuclear, 1998, Volume: 17, Issue:2

    Topics: Antineoplastic Agents; Anxiety; Breast Neoplasms; Diazepam; Female; Fluorine Radioisotopes; Fluorode

1998
Diazepam inhibits forskolin-stimulated adenylyl cyclase activity in human tumour cells.
    Pharmacology & toxicology, 1999, Volume: 85, Issue:4

    Topics: Adenylyl Cyclase Inhibitors; Anti-Anxiety Agents; Breast Neoplasms; Cell Membrane; Colforsin; Diazep

1999
Specific binding of benzodiazepines to human breast cancer cell lines.
    Life sciences, 1999, Volume: 65, Issue:20

    Topics: Benzodiazepinones; Breast Neoplasms; Cell Division; Convulsants; Diazepam; Dose-Response Relationshi

1999
Mind and cancer.
    Lancet (London, England), 1979, May-05, Volume: 1, Issue:8123

    Topics: Animals; Breast Neoplasms; Carcinoma 256, Walker; Diazepam; Female; Growth Substances; Humans; Mamma

1979
[Prophylaxis of complications caused by cytostatic drugs used in oncological patients].
    Vrachebnoe delo, 1979, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents; Breast Neoplasms; Child; Chlorides; Diazepam; Female; Foli

1979
Myofascial pain dysfunction syndrome involving tumor metastasis. Case report.
    Journal of periodontology, 1975, Volume: 46, Issue:5

    Topics: Breast Neoplasms; Diagnosis, Differential; Diazepam; Facial Muscles; Female; Humans; Mandibular Neop

1975
Diazepam use in relation to breast cancer: results from two case-control studies.
    American journal of epidemiology, 1990, Volume: 131, Issue:3

    Topics: Adolescent; Adult; Aged; Breast Neoplasms; Case-Control Studies; Diazepam; Epidemiologic Methods; Fe

1990
Epidemiological screening for potentially carcinogenic drugs.
    Agents and actions. Supplements, 1990, Volume: 29

    Topics: Barbiturates; Breast Neoplasms; Carcinogens; Diazepam; Dose-Response Relationship, Drug; Erythromyci

1990