diazepam has been researched along with Brain Infarction in 3 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Brain Infarction: Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We tested whether diazepam, a GABA-ergic drug that also inhibits brain nitric monoxide formation, improves acute stroke prognosis." | 9.12 | Diazepam to improve acute stroke outcome: results of the early GABA-Ergic activation study in stroke trial. a randomized double-blind placebo-controlled trial. ( Hardy, E; Hilton, A; Kessels, A; Lodder, J; van Raak, L, 2006) |
| "We tested whether diazepam, a GABA-ergic drug that also inhibits brain nitric monoxide formation, improves acute stroke prognosis." | 5.12 | Diazepam to improve acute stroke outcome: results of the early GABA-Ergic activation study in stroke trial. a randomized double-blind placebo-controlled trial. ( Hardy, E; Hilton, A; Kessels, A; Lodder, J; van Raak, L, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rupasinghe, J | 1 |
| Jasinarachchi, M | 1 |
| Kuhmonen, J | 1 |
| Lukkarinen, J | 1 |
| Gröhn, O | 1 |
| Jolkkonen, J | 1 |
| Sivenius, J | 1 |
| Lodder, J | 1 |
| van Raak, L | 1 |
| Hilton, A | 1 |
| Hardy, E | 1 |
| Kessels, A | 1 |
1 trial available for diazepam and Brain Infarction
| Article | Year |
|---|---|
Diazepam to improve acute stroke outcome: results of the early GABA-Ergic activation study in stroke trial. a randomized double-blind placebo-controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Brain Infarction; Cerebral Hemorrhage; Diazepam; Double-Blind Method | 2006 |
2 other studies available for diazepam and Brain Infarction
| Article | Year |
|---|---|
Progressive encephalopathy with cerebral oedema and infarctions associated with valproate and diazepam overdose.
Topics: Adult; Antimanic Agents; Brain Edema; Brain Infarction; Chemical and Drug Induced Liver Injury; Coma | 2011 |
Diazepam does not reduce infarct size in rats subjected to transient occlusion of the middle cerebral artery when normothermia is maintained.
Topics: Animals; Arterial Occlusive Diseases; Body Temperature; Brain Infarction; Brain Ischemia; Cerebral A | 2002 |