Page last updated: 2024-10-25

diazepam and Brain Edema

diazepam has been researched along with Brain Edema in 16 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)

Research Excerpts

ExcerptRelevanceReference
"Cerebral edema is responsible for intracranial hypertension and tentorial herniation, which in turn increase edema through venous compression, ischemia, and hypoxia."1.27[Post-traumatic cerebral edema. Physiopathology and treatment]. ( Jomin, M; Lesoin, F; Lozes, G; Verier, A, 1984)
"22 patients with severe preeclampsia-eclampsia were treated in our Intensive Care Unit from 1972 to 1978."1.26[Intensive care of severe preeclampsia-eclampsia. A report on 22 cases (author's transl)]. ( Larsen, R; Radke, J; Turner, E, 1980)
"Recurrent acute respiratory failure in an epileptic subject is described."1.25Respiratory failure as a seizure phenomenon. A case report. ( Malatinský, J; Procházka, M; Sámel, M, 1975)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199010 (62.50)18.7374
1990's1 (6.25)18.2507
2000's3 (18.75)29.6817
2010's2 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sharma, A1
Castellani, RJ1
Smith, MA1
Muresanu, DF1
Dey, PK1
Sharma, HS1
Domínguez-Fuentes, B1
García-Gil, D1
Romero-Palacios, A1
Sánchez-Crespo, JM1
García-Arjona, R1
Navarro-Navarro, J1
Marchi, N1
Betto, G1
Fazio, V1
Fan, Q1
Ghosh, C1
Machado, A1
Janigro, D1
Rupasinghe, J1
Jasinarachchi, M1
Larney, V1
Dwyer, R1
Verier, A1
Jomin, M1
Lozes, G1
Lesoin, F1
Larsen, R1
Turner, E1
Radke, J1
Bender, AS1
Norenberg, MD1
Rasenack, U1
Gattenlöhner, W1
Khalid, MS1
Schulz, H1
Malatinský, J1
Procházka, M1
Sámel, M1
Iasnetsov, VS1
Novikov, VE1
Lombroso, CT1
Murray, JD1
Fleming, P1
Weber, J1
Hsuen, J1
Bannatyne, R1
Anglin, C1
Weber, M1
Masingue, M1
Martin, JY1
Tridon, P1
Arnould, G1
Ferrero, A1
Marzullo, C1
Salmoiraghi, ML1

Reviews

3 reviews available for diazepam and Brain Edema

ArticleYear
[Tricyclic antidepressive agents: clinical aspects and therapy of poisoning].
    Deutsche medizinische Wochenschrift (1946), 1976, Jul-30, Volume: 101, Issue:31

    Topics: Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Brain Diseases; Brain Edema; Diazepam; Gastr

1976
The treatment of status epilepticus.
    Pediatrics, 1974, Volume: 53, Issue:4

    Topics: Anti-Bacterial Agents; Anticonvulsants; Barbiturates; Brain Edema; Central Nervous System Diseases;

1974
The continuing problem of purulent meningitis in infants and children.
    Pediatric clinics of North America, 1974, Volume: 21, Issue:4

    Topics: Bacterial Vaccines; Bicarbonates; Brain Edema; Diagnosis, Differential; Diazepam; Digoxin; Fever; Ga

1974

Other Studies

13 other studies available for diazepam and Brain Edema

ArticleYear
5-Hydroxytryptophan: A precursor of serotonin influences regional blood-brain barrier breakdown, cerebral blood flow, brain edema formation, and neuropathology.
    International review of neurobiology, 2019, Volume: 146

    Topics: 5-Hydroxytryptophan; Albumins; Animals; Behavior, Animal; Blood-Brain Barrier; Brain; Brain Edema; C

2019
[Posterior reversible leukoencephalopathy in a patient with postpartum eclampsia].
    Medicina intensiva, 2008, Volume: 32, Issue:7

    Topics: Adult; Anticonvulsants; Antihypertensive Agents; Brain; Brain Edema; Cesarean Section; Diazepam; Dru

2008
Blood-brain barrier damage and brain penetration of antiepileptic drugs: role of serum proteins and brain edema.
    Epilepsia, 2009, Volume: 50, Issue:4

    Topics: Analysis of Variance; Animals; Anticonvulsants; Blood Proteins; Blood-Brain Barrier; Brain; Brain Ed

2009
Progressive encephalopathy with cerebral oedema and infarctions associated with valproate and diazepam overdose.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2011, Volume: 18, Issue:5

    Topics: Adult; Antimanic Agents; Brain Edema; Brain Infarction; Chemical and Drug Induced Liver Injury; Coma

2011
Hyponatraemic convulsions and fatal head injury secondary to desmopressin treatment for enuresis.
    European journal of anaesthesiology, 2006, Volume: 23, Issue:10

    Topics: Adult; Anticonvulsants; Antidiuretic Agents; Brain; Brain Edema; Craniocerebral Trauma; Craniotomy;

2006
[Post-traumatic cerebral edema. Physiopathology and treatment].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1984, Mar-01, Volume: 60, Issue:10

    Topics: Alfaxalone Alfadolone Mixture; Barbiturates; Brain Edema; Brain Injuries; Cytidine Diphosphate Choli

1984
[Intensive care of severe preeclampsia-eclampsia. A report on 22 cases (author's transl)].
    Der Anaesthesist, 1980, Volume: 29, Issue:5

    Topics: Acute Kidney Injury; Adolescent; Adult; Brain Edema; Critical Care; Diazepam; Dihydralazine; Eclamps

1980
Effect of benzodiazepines and neurosteroids on ammonia-induced swelling in cultured astrocytes.
    Journal of neuroscience research, 1998, Dec-01, Volume: 54, Issue:5

    Topics: Ammonia; Astrocytes; Atrial Natriuretic Factor; Benzodiazepines; Benzodiazepinones; Brain Edema; Cel

1998
The treatment and management of emergency status epilepticus.
    Epilepsia, 1976, Volume: 17, Issue:1

    Topics: Age Factors; Brain Edema; Child; Chlormethiazole; Diazepam; Emergencies; Epilepsy, Absence; Epilepsy

1976
Respiratory failure as a seizure phenomenon. A case report.
    British journal of anaesthesia, 1975, Volume: 47, Issue:9

    Topics: Brain Edema; Diazepam; Epilepsy; Humans; Male; Middle Aged; Phenobarbital; Respiratory Insufficiency

1975
[The GABA-ergic system and brain edema].
    Biulleten' eksperimental'noi biologii i meditsiny, 1985, Volume: 99, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Benactyzine; Benzodiazepines; Benzodiazepinones; Brain Edema; Brain In

1985
[Diagnostic value of the reactivity of E.E.G. foci to diazepam injection. (Statistical study of 327 cases)].
    Revue neurologique, 1973, Volume: 129, Issue:6

    Topics: Adolescent; Adult; Aged; Brain Abscess; Brain Damage, Chronic; Brain Diseases; Brain Edema; Brain In

1973
[Intensive therapy of gestoses. Our experience in the years 1969-1971].
    Annali di ostetricia, ginecologia, medicina perinatale, 1971, Volume: 92, Issue:12

    Topics: Betamethasone; Brain Edema; Diazepam; Ergoloid Mesylates; Female; Furosemide; Humans; Mannitol; Papa

1971