diazepam has been researched along with Brain Diseases in 57 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We observed dramatic reversal of the clinical symptoms and electroencephalographic abnormalities in four patients with this syndrome who were treated with diazepam." | 3.65 | Dialysis encephalopathy: a possible seizure disorder. ( Nadel, AM; Wilson, WP, 1976) |
| " Across groups, treatment-emergent adverse event rates ranged from 66." | 3.30 | Safety of Diazepam Nasal Spray in Pediatric Patients With Developmental Epileptic Encephalopathies: Results From a Long-term Phase 3 Safety Study. ( Carrazana, E; Misra, SN; Rabinowicz, AL; Segal, EB; Tarquinio, D; Wheless, JW, 2023) |
| "Minimal requirements: seizure-prevention outcome given as fraction of cases; AED or control assigned by random or quasi-random mechanism." | 2.41 | Antiepileptogenesis and seizure prevention trials with antiepileptic drugs: meta-analysis of controlled trials. ( Temkin, NR, 2001) |
| "The double athetosis is featured by increased muscle tonus and irregular small amplitude movement, which appears the most frequently in patients of cerebral palsy." | 2.38 | [Athetosis]. ( Ryu, H; Uemura, K; Yokoyama, T, 1993) |
| "Continuous spike and wave of sleep with encephalopathy (CSWS) is a rare and severe developmental electroclinical epileptic encephalopathy characterized by seizures, abundant sleep activated interictal epileptiform discharges, and cognitive regression or deceleration of expected cognitive growth." | 1.62 | Diazepam induced sleep spindle increase correlates with cognitive recovery in a child with epileptic encephalopathy. ( Baxter, BS; Chinappen, DM; Chu, CJ; Emerton, BC; Grieco, JA; Kramer, MA; Kwon, H; Manoach, DS; McLaren, J; Morgan, AK; Ostrowski, L; Stoyell, SM; Zhu, L, 2021) |
| "To determine the prognostic factors for encephalopathy with bright tree appearance (BTA) in the acute phase through retrospective case evaluation." | 1.42 | Prognostic factors for acute encephalopathy with bright tree appearance. ( Azuma, J; Iwatani, Y; Kagitani-Shimono, K; Kitai, Y; Nabatame, S; Nagai, T; Nakano, S; Okinaga, T; Ozono, K; Tominaga, K; Yamamoto, T, 2015) |
| "Posterior reversible encephalopathy syndrome (PRES) is an acronym that identifies a new clinico-neuroradiologic entity occurring in association with different conditions." | 1.33 | PRES: posterior or potentially reversible encephalopathy syndrome? ( Abbate, M; Ferlazzo, E; Granata, F; Mazzù, I; Musolino, R; Narbone, MC, 2006) |
| "Macro square wave jerks and pendular nystagmus were mildly suppressed after the intramuscular injection of 100 mg of phenobarbital, the oral intake of sodium valproate of 600 mg/day or baclofen of 60 mg/day." | 1.28 | [Multiple system atrophy with macro square wave jerks and pendular nystagmus]. ( Fukusako, T; Morimatsu, M; Nogaki, H; Yamamoto, K, 1992) |
| " The status epilepticus was treated with a high dosage of diazepame." | 1.26 | [Transitory burst-suppression pattern in endogenous-exogenous encephalopathy (author's transl)]. ( Gerstenbrand, F; Hackl, JM; Rumpl, E, 1978) |
| "Dialysis encephalopathy in this patient is compared with other cases recently reported in the medical literature as having a similar dramatic response to diazepam." | 1.26 | Diazepam and dialysis encephalopathy. ( DeMaria, AA; Mann, JD; Snider, WD, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 42 (73.68) | 18.7374 |
| 1990's | 6 (10.53) | 18.2507 |
| 2000's | 5 (8.77) | 29.6817 |
| 2010's | 1 (1.75) | 24.3611 |
| 2020's | 3 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Stoyell, SM | 1 |
| Baxter, BS | 1 |
| McLaren, J | 1 |
| Kwon, H | 1 |
| Chinappen, DM | 1 |
| Ostrowski, L | 1 |
| Zhu, L | 1 |
| Grieco, JA | 1 |
| Kramer, MA | 1 |
| Morgan, AK | 1 |
| Emerton, BC | 1 |
| Manoach, DS | 1 |
| Chu, CJ | 1 |
| Tarquinio, D | 1 |
| Wheless, JW | 1 |
| Segal, EB | 1 |
| Misra, SN | 1 |
| Rabinowicz, AL | 1 |
| Carrazana, E | 1 |
| Supasai, S | 1 |
| González, EA | 1 |
| Rowland, DJ | 1 |
| Hobson, B | 1 |
| Bruun, DA | 1 |
| Guignet, MA | 1 |
| Soares, S | 1 |
| Singh, V | 1 |
| Wulff, H | 1 |
| Saito, N | 1 |
| Harvey, DJ | 1 |
| Lein, PJ | 1 |
| Azuma, J | 1 |
| Nabatame, S | 1 |
| Nakano, S | 1 |
| Iwatani, Y | 1 |
| Kitai, Y | 1 |
| Tominaga, K | 1 |
| Kagitani-Shimono, K | 1 |
| Okinaga, T | 1 |
| Yamamoto, T | 1 |
| Nagai, T | 1 |
| Ozono, K | 1 |
| Landau, WM | 1 |
| FOWLKS, EW | 1 |
| STRICKLAND, DA | 1 |
| PEIRSON, GA | 1 |
| Narbone, MC | 1 |
| Musolino, R | 1 |
| Granata, F | 1 |
| Mazzù, I | 1 |
| Abbate, M | 1 |
| Ferlazzo, E | 1 |
| Melnic, L | 1 |
| Slogoff, S | 1 |
| Girgis, KZ | 1 |
| Keats, AS | 1 |
| Dravet, C | 1 |
| Dalla Bernardina, B | 1 |
| Mesdjian, E | 1 |
| Galland, MC | 1 |
| Roger, J | 1 |
| Baloh, RW | 1 |
| Gilbert, GJ | 1 |
| Simonian, NA | 1 |
| Gilliam, FG | 1 |
| Chiappa, KH | 1 |
| Yokoyama, T | 1 |
| Ryu, H | 1 |
| Uemura, K | 1 |
| Berardelli, A | 1 |
| Inghilleri, M | 1 |
| Priori, A | 1 |
| Marchetti, P | 1 |
| Curra, A | 1 |
| Rona, S | 1 |
| Manfredi, M | 1 |
| Dugdale, AH | 1 |
| Lakhani, KH | 1 |
| Brearley, JC | 1 |
| Inobe, J | 1 |
| Arakawa, T | 1 |
| Mori, T | 1 |
| Kumamoto, T | 1 |
| Tsuda, T | 1 |
| Temkin, NR | 1 |
| Evans, BM | 1 |
| Rumpl, E | 1 |
| Gerstenbrand, F | 1 |
| Hackl, JM | 1 |
| Burke, DJ | 1 |
| Snider, WD | 1 |
| DeMaria, AA | 1 |
| Mann, JD | 1 |
| Ancić, J | 1 |
| Dmitrijević, J | 1 |
| Vernhiet, J | 1 |
| Renou, AM | 1 |
| Orgogozo, JM | 1 |
| Constant, P | 1 |
| Caille, JM | 1 |
| Rasenack, U | 1 |
| Gattenlöhner, W | 1 |
| Zeskov, P | 1 |
| Zosak, J | 1 |
| Georgiev, P | 1 |
| Nadel, AM | 1 |
| Wilson, WP | 1 |
| Raskin, NH | 1 |
| Fishman, RA | 1 |
| Goule, JP | 1 |
| Husson, A | 1 |
| Fondimare, A | 1 |
| Rapoport, F | 1 |
| Lebreton, M | 1 |
| Lajarige, V | 1 |
| Yamamoto, K | 1 |
| Fukusako, T | 1 |
| Nogaki, H | 1 |
| Morimatsu, M | 1 |
| Koh, JY | 1 |
| Choi, DW | 1 |
| Martin, LJ | 1 |
| Doebler, JA | 1 |
| Shih, TM | 1 |
| Anthony, A | 1 |
| Falconer, MA | 1 |
| Greenberg, JO | 1 |
| Cobb, J | 1 |
| Cavazzuti, GB | 1 |
| Williams, R | 1 |
| Kuzemko, JA | 1 |
| Hartley, S | 1 |
| Prokudin, VN | 1 |
| Finne, H | 1 |
| Langevin, P | 1 |
| Grivaux, M | 1 |
| Soulié, J | 1 |
| Diallo, A | 1 |
| Renard, C | 1 |
| Chevalley, J | 1 |
| Nolte, H | 1 |
| von Schnakenburg, K | 1 |
| Weber, M | 2 |
| Masingue, M | 1 |
| Martin, JY | 1 |
| Tridon, P | 2 |
| Arnould, G | 2 |
| Bergmann, K | 1 |
| Pollard, JA | 1 |
| Diemath, HE | 1 |
| Enge, S | 1 |
| Lechner, H | 1 |
| Sawyer, GT | 1 |
| Webster, DD | 1 |
| Schut, LJ | 1 |
| Bower, BD | 1 |
| Courjon, J | 1 |
| Vitols, A | 1 |
| Schmidt, D | 1 |
| Kommerell, G | 1 |
| Nathan, PW | 1 |
| Laxenaire, M | 1 |
| Candia, O | 1 |
| Di Lupo, G | 1 |
9 reviews available for diazepam and Brain Diseases
| Article | Year |
|---|---|
Approach to the dizzy patient.
Topics: Anxiety Disorders; Brain Diseases; Diazepam; Dizziness; Heart Diseases; Humans; Meclizine; Meniere D | 1994 |
[Athetosis].
Topics: Athetosis; Brain Diseases; Clonazepam; Diazepam; Humans; Metabolic Diseases | 1993 |
Inhibitory cortical phenomena studied with the technique of transcranial stimulation.
Topics: Brain Diseases; Cerebral Cortex; Diazepam; Dopamine Agents; Electric Stimulation; GABA Modulators; H | 1996 |
Antiepileptogenesis and seizure prevention trials with antiepileptic drugs: meta-analysis of controlled trials.
Topics: Anticonvulsants; Brain Diseases; Brain Injuries; Carbamazepine; Controlled Clinical Trials as Topic; | 2001 |
[Tricyclic antidepressive agents: clinical aspects and therapy of poisoning].
Topics: Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Brain Diseases; Brain Edema; Diazepam; Gastr | 1976 |
Neurologic disorders in renal failure (first of two parts).
Topics: Blood-Brain Barrier; Brain Diseases; Cerebrospinal Fluid Proteins; Diazepam; Epilepsy; Humans; Lidoc | 1976 |
Problems of fulminant hepatic failure.
Topics: Acute Disease; Adrenal Cortex Hormones; Amylases; Brain Diseases; Brain Stem; Diazepam; Dihydroxyphe | 1972 |
[Features of the clinical effect of benzodiazepine derivatives (according to the findings of comparative studies). Review of the literature].
Topics: Adjustment Disorders; Aggression; Animals; Antisocial Personality Disorder; Barbiturates; Benzazepin | 1973 |
[Cerebral symptoms in the neonatal period. Prognosis and treatment].
Topics: Brain Diseases; Diazepam; Female; Glucose; Humans; Infant, Newborn; Infant, Newborn, Diseases; Metab | 1974 |
4 trials available for diazepam and Brain Diseases
| Article | Year |
|---|---|
Safety of Diazepam Nasal Spray in Pediatric Patients With Developmental Epileptic Encephalopathies: Results From a Long-term Phase 3 Safety Study.
Topics: Anticonvulsants; Brain Diseases; Child; Diazepam; Epilepsy; Epilepsy, Generalized; Humans; Lennox Ga | 2023 |
Randomized clinical trial of magnesium, diazepam, or both after out-of-hospital cardiac arrest.
Topics: Brain Diseases; Diazepam; Drug Therapy, Combination; Heart Arrest; Humans; Magnesium; Neuropsycholog | 2003 |
Etiologic factors in neuropsychiatric complications associated with cardiopulmonary bypass.
Topics: Adult; Brain Diseases; Cardiopulmonary Bypass; Clinical Trials as Topic; Diazepam; Female; Humans; M | 1982 |
Treatment of cerebral irritation in the newborn: double-blind trial with chloral hydrate and diazepam.
Topics: Asphyxia Neonatorum; Body Weight; Brain Diseases; Chloral Hydrate; Clinical Trials as Topic; Diazepa | 1972 |
44 other studies available for diazepam and Brain Diseases
| Article | Year |
|---|---|
Diazepam induced sleep spindle increase correlates with cognitive recovery in a child with epileptic encephalopathy.
Topics: Brain Diseases; Child; Cognition; Diazepam; Electroencephalography; Humans; Sleep | 2021 |
Acute administration of diazepam or midazolam minimally alters long-term neuropathological effects in the rat brain following acute intoxication with diisopropylfluorophosphate.
Topics: Animals; Brain Diseases; Cholinesterase Inhibitors; Diazepam; GABA Modulators; Gliosis; Isoflurophat | 2020 |
Prognostic factors for acute encephalopathy with bright tree appearance.
Topics: Acute Disease; Anti-Anxiety Agents; Brain; Brain Diseases; Child; Child, Preschool; Creatinine; Diaz | 2015 |
CONTROL OF SPASTIC STATES IN NEUROLOGICAL PATIENTS WITH DIAZEPAM.
Topics: Biomedical Research; Brain Diseases; Brain Neoplasms; Central Nervous System Diseases; Diazepam; Dru | 1965 |
PRES: posterior or potentially reversible encephalopathy syndrome?
Topics: Adult; Anti-Inflammatory Agents; Anticonvulsants; Antihypertensive Agents; Brain; Brain Diseases; Cl | 2006 |
[Use of sedatives in seriously ill patients with cerebral neurosurgical disorders].
Topics: Adolescent; Adult; Aged; Brain Diseases; Brain Injuries; Child; Child, Preschool; Diazepam; Female; | 1983 |
[Paroxysmal dyskinesia during treatment with diphenylhydantoin].
Topics: Adult; Brain Diseases; Child; Child, Preschool; Diazepam; Dyskinesia, Drug-Induced; Epilepsy; Female | 1980 |
Diazepam-sensitive encephalopathy.
Topics: Brain Diseases; Dialysis; Diazepam; Humans; Ifosfamide | 1994 |
Ifosfamide causes a diazepam-sensitive encephalopathy.
Topics: Adult; Brain Diseases; Consciousness; Diazepam; Electroencephalography; Female; Humans; Ifosfamide; | 1993 |
Thiopentone induction dose requirement in dogs is little influenced by co-administration of diazepam or prior treatment with phenobarbitone or corticosteroids, but is reduced in the presence of brain pathology.
Topics: Adrenal Cortex Hormones; Anesthesia, Intravenous; Animals; Brain Diseases; Diazepam; Dog Diseases; D | 2001 |
[Acquired pendular nystagmus associated with the lesion of tegmentum mesencephali in a patient with probable multiple sclerosis].
Topics: Adult; Brain Diseases; Clonazepam; Diazepam; Female; gamma-Aminobutyric Acid; Humans; Multiple Scler | 2000 |
Cyclic EEG changes in subacute spongiform and anoxic encephalopathy.
Topics: Acoustic Stimulation; Aged; Arousal; Brain; Brain Diseases; Cerebellum; Cerebral Cortex; Corpus Stri | 1975 |
[Transitory burst-suppression pattern in endogenous-exogenous encephalopathy (author's transl)].
Topics: Adult; Brain Diseases; Cerebral Cortex; Diazepam; Diuretics; Electroencephalography; Female; Humans; | 1978 |
An approach to the treatment of spasticity.
Topics: Adrenergic alpha-Antagonists; Baclofen; Brain Diseases; Dantrolene; Diazepam; Humans; Mephenesin; Mu | 1975 |
Diazepam and dialysis encephalopathy.
Topics: Brain Diseases; Diazepam; Female; Humans; Middle Aged; Renal Dialysis | 1979 |
[The effect of diazepam on slow focal activity registered on the encephalogram. (Clinico-electroencephalographic correlation)].
Topics: Brain Diseases; Cerebrovascular Disorders; Diazepam; Electroencephalography; Humans | 1977 |
Effects of a diazepam-fentanyl mixture on cerebral blood flow and oxygen consumption in man.
Topics: Brain; Brain Diseases; Cerebrovascular Circulation; Diazepam; Fentanyl; Humans; Oxygen Consumption | 1978 |
[Long-term studies and results or rehabilitation in patients with prolonged cerebral coma].
Topics: Brain Diseases; Child, Preschool; Coma; Diazepam; Female; Humans; Physical Therapy Modalities; Time | 1976 |
Dialysis encephalopathy: a possible seizure disorder.
Topics: Brain Diseases; Diazepam; Electroencephalography; Female; Humans; Male; Middle Aged; Renal Dialysis; | 1976 |
[Letter: Encephalopathies due to insoluble salts of bismuth].
Topics: Aged; Bismuth; Brain Diseases; Colitis; Diazepam; Hallucinations; Humans; Meninges; Middle Aged; Mov | 1975 |
[Multiple system atrophy with macro square wave jerks and pendular nystagmus].
Topics: Atrophy; Baclofen; Brain Diseases; Diazepam; Electrooculography; Eye Movements; Female; Humans; Midd | 1992 |
Childhood chloroquine poisonings--Wisconsin and Washington.
Topics: Brain Diseases; Chloroquine; Diazepam; Drug Therapy, Combination; Epinephrine; Female; Humans; Infan | 1988 |
Leads from the MMWR. Childhood chloroquine poisonings--Wisconsin and Washington.
Topics: Brain Diseases; Chloroquine; Diazepam; Drug Therapy, Combination; Epinephrine; Female; Humans; Infan | 1988 |
Effect of anticonvulsant drugs on glutamate neurotoxicity in cortical cell culture.
Topics: Animals; Anticonvulsants; Brain Diseases; Cells, Cultured; Cerebral Cortex; Diazepam; Excitatory Ami | 1987 |
Protective effect of diazepam pretreatment on soman-induced brain lesion formation.
Topics: Animals; Brain Diseases; Diazepam; Male; Myoclonus; Organophosphorus Compounds; Rats; Rats, Inbred S | 1985 |
Mesial temporal (Ammon's horn) sclerosis as a common cause of epilepsy. Aetiology, treatment, and prevention.
Topics: Administration, Oral; Adolescent; Animals; Brain Diseases; Child; Child, Preschool; Diazepam; Epilep | 1974 |
The neurological effects of methyl bromide poisoning.
Topics: Adult; Amobarbital; Brain Diseases; Bromine; Cerebellar Ataxia; Diazepam; Dimercaprol; Electroenceph | 1971 |
Stiff man syndrome: is the lesion at spinal cord or brain stem level.
Topics: Adult; Amenorrhea; Anxiety; Barbiturates; Brain Diseases; Brain Stem; Child, Preschool; Depression; | 1974 |
[Considerations and research on febrile convulsions].
Topics: Anticonvulsants; Brain Diseases; Child, Preschool; Diagnosis, Differential; Diazepam; Electroencepha | 1974 |
[Convulsions in children].
Topics: Adolescent; Adult; Anticonvulsants; Birth Injuries; Brain Diseases; Brain Injuries; Child; Child, Pr | 1973 |
[Therapeutic hyperosmolarity].
Topics: Adult; Bicarbonates; Blood Transfusion; Brain Diseases; Chemical and Drug Induced Liver Injury; Diaz | 1973 |
[Morphological and pharmacological-toxicological aspects of hyperoxia].
Topics: Aminobutyrates; Animals; Atmospheric Pressure; Brain Diseases; Diazepam; Ganglia; Humans; Lung; Lung | 1973 |
[Diagnostic value of the reactivity of E.E.G. foci to diazepam injection. (Statistical study of 327 cases)].
Topics: Adolescent; Adult; Aged; Brain Abscess; Brain Damage, Chronic; Brain Diseases; Brain Edema; Brain In | 1973 |
The lazy respiratory center--or how to recognize a tired horse. Clinical conference in pulmonary disease from Northwestern University-McGaw Medical Center, Chicago.
Topics: Brain Diseases; Chemoreceptor Cells; Chronic Disease; Diagnosis, Differential; Diazepam; Digoxin; Fu | 1974 |
Assessment of therapy in psychogeriatric illness.
Topics: Affective Symptoms; Aged; Antidepressive Agents; Brain Diseases; Delirium; Dementia; Diagnosis, Diff | 1974 |
Hypertensive encephalopathy following anaesthesia.
Topics: Anesthesia, General; Brain Diseases; Diazepam; Female; Humans; Male; Positive-Pressure Respiration; | 1969 |
EEG depth leads during stereotaxic brain surgery. A report on 117 cases (5 target points, effects of 13 different drugs).
Topics: Amides; Amygdala; Antimetabolites; Asparagine; Benzoates; Brain; Brain Diseases; Cerebrovascular Cir | 1970 |
Treatment of uncontrolled seizure activity with diazepam.
Topics: Acute Disease; Adolescent; Adult; Aged; Anticonvulsants; Brain Diseases; Child; Chronic Disease; Com | 1968 |
Minor epileptic status.
Topics: Brain Diseases; Child; Diagnosis, Differential; Diazepam; Epilepsy; Humans; Phenytoin; Primidone | 1972 |
[Value of benzodiazepins injected by the intravenous route].
Topics: Benzazepines; Brain Diseases; Diazepam; Electroencephalography; Epilepsy; Humans; Injections, Intrav | 1971 |
[Seesaw nystagmus with bitemporal hemianopia following head traumas].
Topics: Adult; Brain Diseases; Brain Neoplasms; Congenital Abnormalities; Craniocerebral Trauma; Craniophary | 1969 |
The action of diazepam in neurological disorders with excessive motor activity.
Topics: Brain Diseases; Decerebrate State; Diazepam; Diencephalon; Electromyography; Epilepsy; Hemiplegia; H | 1970 |
[Action of diazepam on E.E.G. focalizations].
Topics: Action Potentials; Brain; Brain Diseases; Diazepam; Electroencephalography; Humans | 1970 |
[Electroencephalographic response to intravenous diazepam in patients with cerebral lesions].
Topics: Brain Diseases; Brain Neoplasms; Carotid Artery Thrombosis; Cerebral Arterial Diseases; Diazepam; El | 1970 |