diazepam has been researched along with Body Weight in 164 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was undertaken to evaluate the effect of acute and repeated (daily and weekly) intravenous (IV) administration of PK 11 195 (PK; 10 mg kg(-1)) on body weight (BW) in Sprague-Dawley male and female rats exposed for 4-8 weeks to diazepam (DZ) slowly released from Silastic capsules (120 and 90 mg/capsule/week for males and females, respectively)." | 7.70 | The effect of PK 11 195, a specific antagonist of the peripheral benzodiazepine receptors, on body weight in rats chronically exposed to diazepam. ( Jing, X; Sloan, JW; Wala, EP, 2000) |
| "In order to investigate the effects of early protein malnutrition and environmental stimulation upon the response to the anxiolytic properties of diazepam, two animal models of anxiety (elevated plus-maze and light-dark transition tests) were used." | 7.69 | Effects of early protein malnutrition and environmental stimulation upon the reactivity to diazepam in two animal models of anxiety. ( Almeida, SS; Daud, MM; de Oliveira, LM; Santucci, LB, 1994) |
| "This study was undertaken to determine the incidence of endotracheal intubation after the use of diazepam compared with phenobarbital or phenytoin in emergency treatment of seizures in children." | 7.68 | Diazepam and intubation in emergency treatment of seizures in children. ( Dimand, RJ; Karr, VA; Kennedy, KJ; Orr, RA; Venkataraman, ST, 1991) |
| "A series of experiments are reported in all of which the effects of chronic (14-18 days) diazepam treatment on body weight were evaluated under various conditions, and one experiment in which weight gain and daily food intake were monitored simultaneously." | 7.66 | The effects of chronic diazepam treatment on body weight and food intake in rats. ( Grimm, VE; Jancourt, A, 1983) |
| "Diazepam rectal gel was effective in stopping seizures in 45 patients (90%)." | 6.73 | Effectiveness of diazepam rectal gel in adults with acute repetitive seizures and prolonged seizures: a single-center experience. ( Bensalem-Owen, M; Chumley, A; Fakhoury, T, 2007) |
| "Prenatal stress may induce intrauterine growth retardation, but it is not known whether a treatment with the anxiolytic benzodiazepine, diazepam may interfere with this phenomenon." | 5.30 | Prenatal stress induces body weight deficit and behavioural alterations in rats: the effect of diazepam. ( Di Leo, F; Drago, F; Giardina, L, 1999) |
| " Results from 2413 mice were evaluated for effects of sex, age, body weight, and latency between administration of atropine methyl bromide and pilocarpine." | 3.78 | Factors affecting outcomes of pilocarpine treatment in a mouse model of temporal lobe epilepsy. ( Buckmaster, PS; Haney, MM, 2012) |
| " In addition, ameliorating effect of ECa 233 was observed on the body weight and serum corticosterone which were adversely affected by immobilization stress." | 3.78 | Anxiolytic effects of standardized extract of Centella asiatica (ECa 233) after chronic immobilization stress in mice. ( Tantisira, B; Tantisira, MH; Wanasuntronwong, A; Watanabe, H, 2012) |
| "The aim of this study was to evaluate the influence of nandrolone decanoate on anxiety levels in rats." | 3.74 | Influence of anabolic steroid on anxiety levels in sedentary male rats. ( Calil, CM; Ferreira, R; Marcondes, FK; Moura, MJ; Rocha, VM, 2007) |
| " In this study, the influence of the following sources of variability on measurement results was examined: (i) sedation with diazepam; (ii) body weight of animals (ranging in age: 40 to 102 days); and (iii) time of the measurement (circadian influences)." | 3.71 | Analysis of respiratory mechanics by impulse oscillometry in non-sedated and diazepam-sedated swine. ( Klein, C; Reinhold, P, 2001) |
| "Changes in body weight (BW) in female rats treated for 5 weeks (wk) with weekly subcutaneous implantation of silastic capsules containing different benzodiazepines (BZs): diazepam (DZ) 90, 180, 360 and 540 mg wk-1; nordiazepam (ND) 600 mg wk-1; oxazepam (OX) 600 mg wk-1 and flunitrazepam (FN) 540 mg wk-1 and in male rats exposed to DZ (540 mg wk-1) were evaluated herein." | 3.70 | The effect of chronic benzodiazepines exposure on body weight in rats. ( Jing, X; Sloan, JW; Wala, EP, 1998) |
| "This study was undertaken to evaluate the effect of acute and repeated (daily and weekly) intravenous (IV) administration of PK 11 195 (PK; 10 mg kg(-1)) on body weight (BW) in Sprague-Dawley male and female rats exposed for 4-8 weeks to diazepam (DZ) slowly released from Silastic capsules (120 and 90 mg/capsule/week for males and females, respectively)." | 3.70 | The effect of PK 11 195, a specific antagonist of the peripheral benzodiazepine receptors, on body weight in rats chronically exposed to diazepam. ( Jing, X; Sloan, JW; Wala, EP, 2000) |
| "Status epilepticus was induced in rats by sequential injections of lithium and pilocarpine." | 3.69 | Cardiac hypertrophy secondary to status epilepticus in the rat. ( Rubinstein, BK; Treiman, DM; Walton, NY, 1995) |
| "In order to investigate the effects of early protein malnutrition and environmental stimulation upon the response to the anxiolytic properties of diazepam, two animal models of anxiety (elevated plus-maze and light-dark transition tests) were used." | 3.69 | Effects of early protein malnutrition and environmental stimulation upon the reactivity to diazepam in two animal models of anxiety. ( Almeida, SS; Daud, MM; de Oliveira, LM; Santucci, LB, 1994) |
| "Long-term behavioral effects of a low dose of diazepam (1 mg/kg body weight) or chlorpromazine (2." | 3.68 | Impact of prenatal low-dose diazepam or chlorpromazine on reflex and motor development and inhibitory-learning. ( Hassmannová, J; Josífko, M; Myslivecek, J, 1991) |
| "This study was undertaken to determine the incidence of endotracheal intubation after the use of diazepam compared with phenobarbital or phenytoin in emergency treatment of seizures in children." | 3.68 | Diazepam and intubation in emergency treatment of seizures in children. ( Dimand, RJ; Karr, VA; Kennedy, KJ; Orr, RA; Venkataraman, ST, 1991) |
| "Separate age groups of C57BL/6 and autoimmune New Zealand Black (NZB) mice were compared for diazepam-induced ataxia and barbiturate-induced loss of righting reflex." | 3.67 | Age-dependent enhancement of diazepam sensitivity is accelerated in New Zealand Black mice. ( Forster, MJ; Lal, H; Popper, MD; Retz, KC, 1986) |
| "The effects of daily oral administration of imipramine hydrochloride (5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz-[b,f]azepine monohydrochloride; 50 mg/kg) and/or diazepam (7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one ; 5 mg/kg) in a 1% aqueous solution of carboxymethylcellulose sodium salt (CMC) on the body weight, organ weights, and activities of various enzymes, including drug metabolizing enzyme systems were investigated in rats during a 15-day period." | 3.67 | Effects of combined administration of diazepam and imipramine hydrochloride in rats. ( Igarashi, T; Kitagawa, H; Ohkawara, S; Ohmori, S; Okiyama, M; Ueno, K, 1986) |
| "Rats on days 12--14 of pregnancy were treated with restraint stress alone (9h daily), restraint stress plus diazepam (1 mg/kg, twice daily), diazepam alone, or left as untreated controls." | 3.66 | Prevention by diazepam of adverse effects of maternal restraint stress on postnatal development and learning in the rat. ( Barlow, SM; Knight, AF; Sullivan, FM, 1979) |
| "Published data on the effect of cirrhosis on diazepam pharmacokinetics were reanalyzed to determine how age, sex, and body weight might have influenced the conclusions." | 3.66 | Factors influencing diazepam pharmacokinetics: age, sex, and liver disease. ( Greenblatt, DJ; Harmatz, JS; Shader, RI, 1978) |
| "A series of experiments are reported in all of which the effects of chronic (14-18 days) diazepam treatment on body weight were evaluated under various conditions, and one experiment in which weight gain and daily food intake were monitored simultaneously." | 3.66 | The effects of chronic diazepam treatment on body weight and food intake in rats. ( Grimm, VE; Jancourt, A, 1983) |
| " Diazepam, administered at 6 mg/kg body weight immobilized a tame pronghorn fawn within 30 min." | 3.66 | Oral administration of diazepam and promazine hydrochloride to immobilize pronghorn. ( Hibler, CP; Pojar, TM; Pusateri, FM, 1982) |
| "The hyperphagia characteristic of some types of obesity may result from a deficiency in one or more components of the systems controlling satiety which in rats may include the gastrointestinal hormone cholecystokinin (CCK)." | 3.66 | Cholecystokinin, amphetamine and diazepam and feeding in lean and obese Zucker rats. ( Baile, CA; McLaughlin, CL, 1979) |
| "Diazepam rectal gel was effective in stopping seizures in 45 patients (90%)." | 2.73 | Effectiveness of diazepam rectal gel in adults with acute repetitive seizures and prolonged seizures: a single-center experience. ( Bensalem-Owen, M; Chumley, A; Fakhoury, T, 2007) |
| "Diazepam treated patients improved significantly more early in the trial, according to a few measures." | 2.64 | Doxepin or diazepam for anxious and anxious-depressed outpatients? ( Fisher, S; Gambill, JD; Gardos, G; Haskell, DS; McNair, DM, 1978) |
| "In mice, influenza induced dynamic changes in immune cell GABAA subunit expression: α1 subunits decreased on alveolar macrophage, but increased on monocytes, CD4+ and CD8+ T cells." | 1.42 | Immune cell expression of GABAA receptors and the effects of diazepam on influenza infection. ( Godlee, A; Goulding, J; Grover, V; Gurney, S; Hussell, T; Ma, D; Maze, M; Sanders, RD; Singh, S; Snelgrove, R, 2015) |
| "Therapy of seizure activity following exposure to the nerve agent soman (GD) includes treatment with the anticonvulsant diazepam (DZP), an allosteric modulator of γ-aminobutyric acid A (GABA(A)) receptors." | 1.38 | The anticholinergic and antiglutamatergic drug caramiphen reduces seizure duration in soman-exposed rats: synergism with the benzodiazepine diazepam. ( Kelley, NR; Lee, RB; Lumley, LA; Moffett, MC; Schultz, MK; Schwartz, JE; Stone, MF; Wright, LK, 2012) |
| " Dose-response assessments demonstrated that rats housed in EE showed reduced sensitivity to the behavioural effects of DZP and DMI but increased sensitivity to the locomotor-enhancing effects of AMP compared to SC and IC; while IC animals exhibited the clearest dose-response effects to increasing doses of DMI." | 1.38 | The effects of isolated and enriched housing conditions on baseline and drug-induced behavioural responses in the male rat. ( Kelly, JP; Simpson, J, 2012) |
| "Diazepam treatment alone exerts metabolic consequences, such as elevated muscle glycogen and plasma FFA and depressed blood glucose levels, which are similar to those observed with exercise training." | 1.32 | Effect of diazepam treatment on metabolic indices in trained and untrained rats. ( Bussieres, LM; Fielding, W; Noble, EG; Pettigrew, FP; Radak, Z; Taylor, AW; Tremblay, M, 2003) |
| "When PK 11195 was administered weekly (5 weeks), rather than daily, tolerance did not develop in either sex." | 1.31 | The pharmacodynamics of PK 11195 in diazepam-dependent male and female rats. ( Holtman, JR; Jing, X; Sloan, JW; Wala, EP, 2000) |
| "In diazepam-treated rats, GABA content of the hypothalamus was unaffected by stresses but that of the hippocampus was slightly decreased." | 1.31 | Diazepam-like effects of a fish protein hydrolysate (Gabolysat PC60) on stress responsiveness of the rat pituitary-adrenal system and sympathoadrenal activity. ( Bernet, F; Dupouy, JP; Montel, V; Noël, B, 2000) |
| " bovis in adult hamsters after in utero exposure to a dosage of 1." | 1.30 | Effects of prenatal diazepam treatment on Mycobacterium bovis-induced infection in hamsters. ( Guerra, JL; Palermo-Neto, J; Pinheiro, SR; Ugaz, EM, 1999) |
| "Prenatal stress may induce intrauterine growth retardation, but it is not known whether a treatment with the anxiolytic benzodiazepine, diazepam may interfere with this phenomenon." | 1.30 | Prenatal stress induces body weight deficit and behavioural alterations in rats: the effect of diazepam. ( Di Leo, F; Drago, F; Giardina, L, 1999) |
| "After stopping the treatment, the body weight and food consumption in the diazepam 100 and 300 mg/kg groups tended to decrease or decreased to values lower than those in the control group, whereas these parameters in the S-(+)-DN-2327 30, 100 and 300 mg/kg groups were comparable to the control group values." | 1.29 | A nonbenzodiazepine partial agonist, S-(+)-DN-2327, has minimal physical dependence-producing liability, but shows cross-dependence on barbital in rats. ( Awasaki, Y; Inui, Y; Nishida, N; Yamamoto, M, 1996) |
| "When diazepam (2 mg/kg) was automatically injected at 3-h intervals for 10 consecutive days, tolerance did not develop to the hyperphagia and body weight was increased significantly following diazepam injection." | 1.29 | Effects of repeated intravenous administration of diazepam on food intake in rats. ( Naruse, T, 1994) |
| " Rats were chronically fed food containing diazepam on an escalating drug dosage schedule, from 1 and 2 to 12 mg/g of food, over a period of 30 days." | 1.28 | Genetic differences in the development of physical dependence upon diazepam in Lewis and Fischer 344 inbred rat strains. ( Lu, MS; Misawa, M; Motegi, H; Suzuki, T; Yoshii, T, 1992) |
| " Flupirtine yielded a dose-response curve with an ED50 of 3." | 1.28 | Investigations with the novel non-opioid analgesic flupirtine in regard to possible benzodiazepine-like abuse inducing potential. ( Borbe, HO; Nickel, B; Szelenyi, I, 1990) |
| " However, the distributions of elimination half-life (44." | 1.28 | A large-sample study of diazepam pharmacokinetics. ( Friedman, H; Greenblatt, DJ; Harmatz, JS; Locniskar, A; Shader, RI, 1989) |
| "Group III served as control." | 1.28 | [Muscular rigidity caused by alfentanil: prevention]. ( Curatolo, M; Di Giandomenico, E; Maggio, G; Montanini, S; Santamaria, LB; Sinardi, AU; Venuti, FS, 1989) |
| "Dogs, surgically implanted with a gastric fistula, were chronically dosed with diazepam or lorazepam." | 1.27 | Physical dependence on diazepam and lorazepam in the dog. ( Cherian, S; Martin, WR; McNicholas, LF, 1983) |
| "Diazepam was administered to Swiss-Webster mice for 53 days as a mixture of drug in laboratory chow, leading to consumption as high as 1000 mg/kg/day." | 1.27 | Benzodiazepine dependence in mice after ingestion of drug-containing food pellets. ( Gallaher, EJ; Henauer, SA; Hollister, LE; Jacques, CJ, 1986) |
| "7 mg/kg/day), on the gradedly increased dosage schedule with a dosage level of 0." | 1.27 | [Physical dependence liability test of 4-(o-benzylphenoxy)-N-methylbutylamine hydrochloride (MCI-2016) in rats]. ( Imamaki, H; Ogawa, K; Suzuki, T; Yanaura, S; Yoshii, T, 1987) |
| "Diazepam was more effective than oxazepam and its effect was proportionate to dose." | 1.27 | Tumor-promoting activity of benzodiazepine tranquilizers, diazepam and oxazepam, in mouse liver. ( Diwan, BA; Rice, JM; Ward, JM, 1986) |
| " During chronic administration of brotizolam, triazolam and diazepam all animals gained body weight." | 1.27 | Physical dependence capacity of brotizolam in rhesus monkeys. 2nd communication: primary dependence and barbital substitution. ( Stockhaus, K, 1986) |
| "Dogs, surgically implanted with a chronic gastric fistula, were chronically dosed with N-desmethyldiazepam (32 mg/kg/day) in four divided doses to attain N-desmethyldiazepam plasma levels comparable to those observed in dogs dependent on diazepam (60 mg/kg/day)." | 1.27 | N-desmethyldiazepam physical dependence in dogs. ( Martin, WR; McNicholas, LF; Pruitt, TA, 1985) |
| "Buspirone-treated rats gain weight during withdrawal, suggesting that this novel anxiolytic should lack dependence liability in man." | 1.27 | Lack of withdrawal signs of dependence following cessation of treatment or Ro-15,1788 administration to rats chronically treated with buspirone. ( Eison, MS, 1986) |
| "Mequitazine is a new phenothiazine derivative with potent antihistaminic activity developed by Pharmuka, Co." | 1.26 | [Studies on the barbital-type physical dependence liability of mequitazine in mice and rats (author's transl)]. ( Kaneto, H, 1981) |
| " Rats were made dependent on diazepam by the chronic administration of this drug in the diet." | 1.26 | Effect of p-chlorophenylalanine on diazepam withdrawal signs in rats. ( Fukumori, R; Kitagawa, H; Satoh, T; Suzuki, T; Yanaura, S; Yoshii, T, 1980) |
| " The plasma half-life (t1/2), the elimination coefficient (Kbeta), the concentration (Css), and the apparent volume of distribution (Vbeta) were calculated at steady state, and the mean values +/- SEM were 53 +/- 6 h, 0." | 1.26 | Pharmacokinetics of N-desmethyldiazepam in healthy volunteers after single daily doses of dipotassium chlorazepate. ( Bertler, A; Lindgren, S; Malmgren, H; Post, C, 1977) |
| " Our data indicate that long-term administration (8 months) of diazepam (Valium) 0." | 1.26 | Long-term effects of diazepam on plasma lipids and atheroma in roosters fed in atherogenic diet. ( David, SN; Johnson, FB; Nightingale, TE; Orimilikwe, SO; Patel, DJ; Richardi, JC; Wong, HY, 1980) |
| "The bioavailability of diazepam (I) in uncoated tablets in beagles was tested using tablets tested previously in humans." | 1.26 | Correlation of the bioavailability of diazepam from uncoated tablets in beagle dogs with its dissolution rate and bioavailability in humans. ( Aoyagi, N; Ejima, A; Kaniwa, N; Koibuchi, M; Nishida, Y; Ogata, H; Ogawa, Y; Shibazaki, T; Shimamoto, T; Uda, Y; Yashiki, T, 1982) |
| "Diazepam was given to weaned piglets intramuscularly (0." | 1.26 | [Use of diazepam for medication of feed for pigs]. ( Dvorák, M, 1980) |
| " The rats (drug dependence-experimented rats) who survived the first stage of this experiment were continuously subjected to re-administration by the same dosage schedule as in Exp." | 1.25 | [Comparison of development of drug dependence in naive and drug dependence-experienced rats]. ( Tagashira, E; Yanaura, S, 1975) |
| " Physical dependence on phenobarbital and diazepam was produced using the same dosage schedules as with morphine." | 1.25 | Physical dependence on morphine, phenobarbital and diazepam in rats by drug-admixed food ingestion. ( Suzuki, T; Tagashira, E; Yanaura, S, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 98 (59.76) | 18.7374 |
| 1990's | 38 (23.17) | 18.2507 |
| 2000's | 19 (11.59) | 29.6817 |
| 2010's | 9 (5.49) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tepolt, FA | 1 |
| Bido, J | 1 |
| Burgess, S | 1 |
| Micheli, LJ | 1 |
| Kocher, MS | 1 |
| Estork, DM | 1 |
| Gusmão, DF | 1 |
| Paciencia, ML | 1 |
| Díaz, IE | 1 |
| Varella, AD | 1 |
| Younes, RN | 1 |
| Reis, LF | 1 |
| Montero, EF | 1 |
| Bernardi, MM | 1 |
| Suffredini, IB | 1 |
| Sanders, RD | 1 |
| Grover, V | 1 |
| Goulding, J | 1 |
| Godlee, A | 1 |
| Gurney, S | 1 |
| Snelgrove, R | 1 |
| Ma, D | 1 |
| Singh, S | 1 |
| Maze, M | 1 |
| Hussell, T | 1 |
| Spiers, JG | 1 |
| Chen, HC | 1 |
| Steyn, FJ | 1 |
| Lavidis, NA | 1 |
| Woodruff, TM | 1 |
| Lee, JD | 1 |
| Carregaro, AB | 1 |
| Gerardi, PM | 1 |
| Honsho, DK | 1 |
| Huemer, HP | 1 |
| Lassnig, C | 1 |
| Nowotny, N | 1 |
| Irschick, EU | 1 |
| Kitchen, M | 1 |
| Pavlic, M | 1 |
| Schultz, MK | 1 |
| Wright, LK | 1 |
| Stone, MF | 1 |
| Schwartz, JE | 1 |
| Kelley, NR | 1 |
| Moffett, MC | 1 |
| Lee, RB | 1 |
| Lumley, LA | 1 |
| Buckmaster, PS | 1 |
| Haney, MM | 1 |
| Simpson, J | 1 |
| Kelly, JP | 1 |
| Wanasuntronwong, A | 1 |
| Tantisira, MH | 1 |
| Tantisira, B | 1 |
| Watanabe, H | 1 |
| Haberal, M | 1 |
| Emiroğlu, R | 1 |
| Arslan, G | 1 |
| Apek, E | 1 |
| Karakayali, H | 1 |
| Bilgin, N | 1 |
| Kamei, J | 1 |
| Miyata, S | 1 |
| Morita, K | 1 |
| Saitoh, A | 1 |
| Takeda, H | 1 |
| Tremblay, M | 1 |
| Bussieres, LM | 1 |
| Pettigrew, FP | 1 |
| Fielding, W | 1 |
| Noble, EG | 1 |
| Radak, Z | 1 |
| Taylor, AW | 2 |
| Aerden, LA | 1 |
| Kessels, FA | 1 |
| Rutten, BP | 1 |
| Lodder, J | 1 |
| Steinbusch, HW | 1 |
| Schleimer, SB | 1 |
| Johnston, GA | 1 |
| Henderson, JM | 1 |
| Koros, E | 1 |
| Bienkowski, P | 1 |
| Kostowski, W | 1 |
| Parkinson, A | 1 |
| Leonard, N | 1 |
| Draper, A | 1 |
| Ogilvie, BW | 1 |
| Graham, DL | 1 |
| Diaz-Granados, JL | 1 |
| Françolin-Silva, AL | 1 |
| da Silva Hernandes, A | 1 |
| Fukuda, MT | 1 |
| Valadares, CT | 1 |
| Almeida, SS | 3 |
| Tonkiss, J | 1 |
| Galler, J | 1 |
| Fakhoury, T | 1 |
| Chumley, A | 1 |
| Bensalem-Owen, M | 1 |
| Rocha, VM | 1 |
| Calil, CM | 1 |
| Ferreira, R | 1 |
| Moura, MJ | 1 |
| Marcondes, FK | 1 |
| Longstreth, GF | 1 |
| O'Brien, PM | 1 |
| Youkeles, LF | 1 |
| Birger, M | 1 |
| Homburg, R | 1 |
| Insler, V | 1 |
| Kaneto, H | 3 |
| McNicholas, LF | 2 |
| Martin, WR | 2 |
| Cherian, S | 1 |
| de Gier, JJ | 1 |
| Suzuki, T | 6 |
| Fukumori, R | 1 |
| Yoshii, T | 3 |
| Yanaura, S | 5 |
| Satoh, T | 1 |
| Kitagawa, H | 2 |
| Gross, H | 1 |
| Ebert, MH | 1 |
| Faden, VB | 1 |
| Goldberg, SC | 1 |
| Kaye, WH | 1 |
| Caine, ED | 1 |
| Hawks, R | 1 |
| Zinberg, N | 1 |
| Frieder, B | 1 |
| Epstein, S | 1 |
| Grimm, VE | 3 |
| Dvorák, M | 1 |
| Abernethy, DR | 1 |
| Greenblatt, DJ | 4 |
| Divoll, M | 1 |
| Shader, RI | 4 |
| Ogata, H | 1 |
| Aoyagi, N | 1 |
| Kaniwa, N | 1 |
| Koibuchi, M | 1 |
| Shibazaki, T | 1 |
| Ejima, A | 1 |
| Shimamoto, T | 1 |
| Yashiki, T | 1 |
| Ogawa, Y | 1 |
| Uda, Y | 1 |
| Nishida, Y | 1 |
| Gai, N | 1 |
| Fujii, T | 2 |
| Yamamoto, N | 1 |
| Fuchino, K | 1 |
| Jancourt, A | 1 |
| Tesseromatis, C | 1 |
| Galanopoulou, P | 1 |
| Varonos, D | 1 |
| Pusateri, FM | 1 |
| Hibler, CP | 1 |
| Pojar, TM | 1 |
| Patel, DJ | 2 |
| Wong, HY | 2 |
| Newman, HA | 1 |
| Nightingale, TE | 2 |
| Frasinel, C | 1 |
| Johnson, FB | 2 |
| Patel, S | 1 |
| Coleman, B | 1 |
| Gelfman, SS | 1 |
| Gracely, RH | 1 |
| Driscoll, EJ | 1 |
| Butler, D | 1 |
| Sweet, JB | 1 |
| Wirdzek, PR | 1 |
| Richardi, JC | 1 |
| Orimilikwe, SO | 1 |
| David, SN | 1 |
| Segal, M | 1 |
| Allen, MD | 1 |
| Harmatz, JS | 3 |
| Hartung, HJ | 1 |
| Osswald, PM | 1 |
| Abel, J | 1 |
| Walton, NY | 1 |
| Rubinstein, BK | 1 |
| Treiman, DM | 1 |
| Schroeder, H | 2 |
| Collignon, A | 1 |
| Uttscheid, L | 1 |
| Pereira de Vasconcelos, A | 1 |
| Nehlig, A | 2 |
| Santucci, LB | 1 |
| Daud, MM | 1 |
| de Oliveira, LM | 2 |
| Vivian, JA | 1 |
| Farrell, WJ | 1 |
| Sapperstein, SB | 1 |
| Miczek, KA | 1 |
| Naruse, T | 1 |
| Pesce, ME | 1 |
| Acevedo, X | 1 |
| Pinardi, G | 1 |
| Miranda, HF | 1 |
| Brock, N | 1 |
| Mizoguchi, H | 2 |
| Shirayama, N | 1 |
| Tsuda, M | 1 |
| Yoshiike, M | 1 |
| Misawa, M | 3 |
| Dingwall, B | 1 |
| Reeve, B | 1 |
| Hutchinson, M | 1 |
| Smith, PF | 1 |
| Darlington, CL | 1 |
| Balon, R | 1 |
| Yeragani, VK | 1 |
| Pohl, R | 1 |
| Merlos, B | 1 |
| Sherwood, P | 1 |
| Motegi, H | 2 |
| Awano, H | 1 |
| Atsmon, J | 1 |
| Oaknin, S | 1 |
| Laudon, M | 1 |
| Laschiner, S | 1 |
| Gavish, M | 1 |
| Dagan, Y | 1 |
| Zisapel, N | 1 |
| Inui, Y | 1 |
| Yamamoto, M | 1 |
| Awasaki, Y | 1 |
| Nishida, N | 1 |
| Ely, DR | 1 |
| Dapper, V | 1 |
| Marasca, J | 1 |
| Corrêa, JB | 1 |
| Gamaro, GD | 1 |
| Xavier, MH | 1 |
| Michalowski, MB | 1 |
| Catelli, D | 1 |
| Rosat, R | 1 |
| Ferreira, MB | 1 |
| Dalmaz, C | 1 |
| Padilla, J | 1 |
| Fielding, WC | 1 |
| Belcastro, AN | 1 |
| Gardiner, PF | 1 |
| Jing, X | 5 |
| Wala, EP | 4 |
| Sloan, JW | 5 |
| Wala, E | 1 |
| Holtman, JR | 3 |
| Milliken, B | 1 |
| Toniolo, AM | 1 |
| Desor, D | 1 |
| Drago, F | 1 |
| Di Leo, F | 1 |
| Giardina, L | 1 |
| Ugaz, EM | 1 |
| Pinheiro, SR | 1 |
| Guerra, JL | 1 |
| Palermo-Neto, J | 1 |
| Hack, JB | 1 |
| Leviss, JA | 1 |
| Nelson, LS | 1 |
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| Pichlmayr, I | 1 |
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| Jänicke, B | 1 |
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| Hassmannová, J | 1 |
| Josífko, M | 1 |
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| Dimand, RJ | 1 |
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| Segovia, S | 1 |
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| Rodríguez-Zafra, M | 1 |
| Calés, JM | 1 |
| Del Abril, A | 1 |
| De Blas, MR | 1 |
| Collado, P | 1 |
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| Steinberg, JL | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of the Effect of Intra-articular Administration of 2% Ropivacaine vs. 7.5% Ropivacaine as an Analgesic in the Immediate Postoperative Period of Knee Arthroscopy in Acute Injuries at the ABC Medical Center[NCT05807945] | Phase 4 | 68 participants (Actual) | Interventional | 2020-04-01 | Completed | ||
| Effect of Preoperative Counseling on Postoperative Opioid Use Following Knee Arthroscopy. A Randomized Controlled Trial.[NCT04083209] | 43 participants (Actual) | Interventional | 2019-10-15 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for diazepam and Body Weight
| Article | Year |
|---|---|
Pitfalls in the use of anesthetic agents in children.
Topics: Adolescent; Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics; Barbiturates; Body | 1985 |
Toxic effects of anticonvulsants: general principles.
Topics: Adrenocorticotropic Hormone; Adult; Anticonvulsants; Benzodiazepinones; Body Surface Area; Body Weig | 1974 |
19 trials available for diazepam and Body Weight
| Article | Year |
|---|---|
Living-donor nephrectomy under combined spinal-epidural anesthesia.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Spinal; Body Weight; Diazepam; Humans; Living Donors; Middl | 2002 |
Effectiveness of diazepam rectal gel in adults with acute repetitive seizures and prolonged seizures: a single-center experience.
Topics: Acute Disease; Administration, Rectal; Adolescent; Adult; Anticonvulsants; Body Weight; Diazepam; Di | 2007 |
A double-blind trial of delta 9-tetrahydrocannabinol in primary anorexia nervosa.
Topics: Adult; Affective Symptoms; Anorexia Nervosa; Body Weight; Clinical Trials as Topic; Diazepam; Double | 1983 |
Recovery following intravenous sedation during dental surgery performed under local anesthesia.
Topics: Adolescent; Adult; Anesthesia, Dental; Anesthesia, Local; Body Weight; Diazepam; Female; Fentanyl; H | 1980 |
Changes in appetite and weight during the pharmacological treatment of patients with panic disorder.
Topics: Adult; Agoraphobia; Appetite; Body Weight; Diazepam; Dietary Carbohydrates; Double-Blind Method; Fem | 1993 |
Evaluation of the safety and therapeutic effects of lorazepam on long-term use.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Blood Pressure; Body Weight; Clinical Trials as Topic; Diaze | 1975 |
Doxepin or diazepam for anxious and anxious-depressed outpatients?
Topics: Adolescent; Adult; Aged; Ambulatory Care; Anxiety; Body Weight; Clinical Trials as Topic; Depression | 1978 |
Double-blind clinical evaluation of mazindol (42-548) in obese diabetics.
Topics: Body Weight; Clinical Trials as Topic; Diabetes Mellitus; Diazepam; Drug Evaluation; Female; Glucose | 1975 |
Plasma diazepam levels after single dose oral and intramuscular administration.
Topics: Administration, Oral; Adult; Body Weight; Chromatography, Gas; Clinical Trials as Topic; Diazepam; H | 1975 |
A comparison of lorazepam, diazepam and placebo in the treatment of anxiety states.
Topics: Adolescent; Adult; Anxiety Disorders; Benzodiazepinones; Blood Pressure; Body Weight; Chlorobenzenes | 1974 |
[Investigation on the time series of the hand-tremor amplitude under the influence of different pharmacas (author's transl)].
Topics: Adult; Body Height; Body Weight; Caffeine; Diazepam; Ethanol; Glucose; Hand; Humans; Nicotine; Place | 1974 |
The amnesic actions of diazepam.
Topics: Amnesia; Anesthesia, Local; Body Weight; Diazepam; Dose-Response Relationship, Drug; Female; Humans; | 1974 |
Treatment of cerebral irritation in the newborn: double-blind trial with chloral hydrate and diazepam.
Topics: Asphyxia Neonatorum; Body Weight; Brain Diseases; Chloral Hydrate; Clinical Trials as Topic; Diazepa | 1972 |
Effect of loading and labyrinthine stimulation on body movement.
Topics: Adult; Body Weight; Caffeine; Clinical Trials as Topic; Diazepam; Ear, Inner; Electric Stimulation; | 1973 |
A double blind comparison between doxepin and diazepam in the treatment of states of anxiety.
Topics: Adolescent; Adult; Aged; Anxiety; Body Weight; Clinical Trials as Topic; Depression; Diazepam; Doxep | 1974 |
Operative blood loss in guillotine tonsillectomy and adenoidectomy in children: a comparison of three premedicant drugs.
Topics: Adenoidectomy; Blood Volume; Body Weight; Child; Child, Preschool; Colorimetry; Diazepam; Female; He | 1973 |
Intramuscular diazepam as anti-anxiety agent in SCC-modified EST.
Topics: Adult; Age Factors; Anxiety; Body Weight; Clinical Trials as Topic; Diazepam; Electroconvulsive Ther | 1969 |
Relief of anxiety and related emotions in patients with gastrointestinal disorders. A double-blind controlled study.
Topics: Adult; Aged; Anxiety; Body Weight; Clinical Trials as Topic; Diazepam; Evaluation Studies as Topic; | 1971 |
Efficacy of oral psychosedative drugs for preanesthetic medication.
Topics: Adult; Age Factors; Anxiety; Body Weight; Diazepam; Ethchlorvynol; Female; Humans; Hydroxyzine; Hypn | 1968 |
143 other studies available for diazepam and Body Weight
| Article | Year |
|---|---|
Opioid Overprescription After Knee Arthroscopy and Related Surgery in Adolescents and Young Adults.
Topics: Adolescent; Adult; Analgesics, Opioid; Arthroscopy; Body Weight; Child; Diazepam; Drug Prescriptions | 2018 |
Opioid Overprescription After Knee Arthroscopy and Related Surgery in Adolescents and Young Adults.
Topics: Adolescent; Adult; Analgesics, Opioid; Arthroscopy; Body Weight; Child; Diazepam; Drug Prescriptions | 2018 |
Opioid Overprescription After Knee Arthroscopy and Related Surgery in Adolescents and Young Adults.
Topics: Adolescent; Adult; Analgesics, Opioid; Arthroscopy; Body Weight; Child; Diazepam; Drug Prescriptions | 2018 |
Opioid Overprescription After Knee Arthroscopy and Related Surgery in Adolescents and Young Adults.
Topics: Adolescent; Adult; Analgesics, Opioid; Arthroscopy; Body Weight; Child; Diazepam; Drug Prescriptions | 2018 |
First chemical evaluation and toxicity of Casinga-cheirosa to Balb-c male mice.
Topics: alpha-Tocopherol; Animals; Body Weight; Diazepam; Gastrointestinal Hemorrhage; Humans; Lethal Dose 5 | 2014 |
Immune cell expression of GABAA receptors and the effects of diazepam on influenza infection.
Topics: Animals; Body Weight; Diazepam; Disease Models, Animal; Female; GABA Modulators; Gene Expression Reg | 2015 |
Noninvasive assessment of altered activity following restraint in mice using an automated physiological monitoring system.
Topics: Animals; Anti-Anxiety Agents; Body Weight; Corticosterone; Diazepam; Eating; Locomotion; Male; Mice; | 2017 |
Allometric scaling of chemical restraint associated with inhalant anesthesia in giant anteaters.
Topics: Acepromazine; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Combined; Animals; An | 2009 |
Diazepam leads to enhanced severity of orthopoxvirus infection and immune suppression.
Topics: Alprazolam; Animals; Antibodies, Viral; Antibody Formation; Apoptosis; Body Weight; Cell Proliferati | 2010 |
The anticholinergic and antiglutamatergic drug caramiphen reduces seizure duration in soman-exposed rats: synergism with the benzodiazepine diazepam.
Topics: Acetylcholinesterase; Animals; Anticonvulsants; Body Temperature; Body Weight; Cholinergic Antagonis | 2012 |
Factors affecting outcomes of pilocarpine treatment in a mouse model of temporal lobe epilepsy.
Topics: Age Factors; Animals; Anticonvulsants; Atropine; Body Weight; Diazepam; Disease Models, Animal; Epil | 2012 |
The effects of isolated and enriched housing conditions on baseline and drug-induced behavioural responses in the male rat.
Topics: Amphetamine; Analysis of Variance; Animals; Anti-Anxiety Agents; Behavior, Animal; Body Weight; Cent | 2012 |
Anxiolytic effects of standardized extract of Centella asiatica (ECa 233) after chronic immobilization stress in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Body Weight; Centella; Corticosterone; Diaz | 2012 |
Effects of selective serotonin reuptake inhibitors on immobility time in the tail suspension test in streptozotocin-induced diabetic mice.
Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Anxiety Agents; Blood Glucose; Body Weight; Desipramine; | 2003 |
Effect of diazepam treatment on metabolic indices in trained and untrained rats.
Topics: Animals; Anti-Anxiety Agents; Blood Glucose; Body Weight; Diazepam; Fatty Acids, Nonesterified; Live | 2003 |
Diazepam reduces brain lesion size in a photothrombotic model of focal ischemia in rats.
Topics: Animals; Anticonvulsants; Body Weight; Brain Ischemia; Cerebral Infarction; Diazepam; Disease Models | 2004 |
Novel oral drug administration in an animal model of neuroleptic therapy.
Topics: Administration, Oral; Animals; Antipsychotic Agents; Behavior, Animal; Body Weight; Brain; Clozapine | 2005 |
Effects of 5,7-dihydroxytryptamine lesion of the dorsal raphe nucleus on ethanol discrimination in the rat.
Topics: 5,7-Dihydroxytryptamine; Animals; Body Weight; Central Nervous System Depressants; Diazepam; Discrim | 2005 |
On the mechanism of hepatocarcinogenesis of benzodiazepines: evidence that diazepam and oxazepam are CYP2B inducers in rats, and both CYP2B and CYP4A inducers in mice.
Topics: Animals; Benzodiazepines; Blotting, Western; Body Weight; Carcinogens; Cytochrome P-450 CYP1A1; Cyto | 2006 |
Periadolescent exposure to ethanol and diazepam alters the aversive properties of ethanol in adult mice.
Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Body Weight; Brain; Central Nervous System Depress | 2006 |
Anxiolytic-like effects of short-term postnatal protein malnutrition in the elevated plus-maze test.
Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Behavior, Animal; Body Weight; Diazepam; Dose-Respon | 2006 |
Prenatal malnutrition alters diazepam-mediated suppression of ultrasonic vocalizations in an age dependent manner.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Body Temperature; Body Wei | 2007 |
Influence of anabolic steroid on anxiety levels in sedentary male rats.
Topics: Anabolic Agents; Animals; Anxiety; Behavior, Animal; Body Weight; Brain; Diazepam; Male; Maze Learni | 2007 |
Determinants of the intravenous diazepam dose required for gastroscopy.
Topics: Age Factors; Alcohol Drinking; Anti-Anxiety Agents; Body Weight; Diazepam; Dose-Response Relationshi | 1980 |
Clinical evaluation of fetal movements.
Topics: Body Weight; Diazepam; Female; Fetus; Humans; Movement; Parity; Pregnancy; Pregnancy Complications; | 1980 |
[Studies on the barbital-type physical dependence liability of mequitazine in mice and rats (author's transl)].
Topics: Animals; Barbital; Body Weight; Central Nervous System Depressants; Chlorpromazine; Diazepam; Histam | 1981 |
Physical dependence on diazepam and lorazepam in the dog.
Topics: Animals; Anti-Anxiety Agents; Body Weight; Diazepam; Dogs; Female; Gait; Humans; Lorazepam; Pyrazole | 1983 |
Driving tests with patients.
Topics: Adult; Age Factors; Automobile Driving; Body Weight; Carbolines; Diazepam; Histamine H1 Antagonists; | 1984 |
Effect of p-chlorophenylalanine on diazepam withdrawal signs in rats.
Topics: Animals; Body Weight; Brain Chemistry; Diazepam; Drug Synergism; Eating; Fenclonine; Humans; Hydroxy | 1980 |
The effects of exposure to diazepam during various stages of gestation or during lactation on the development and behavior of rat pups.
Topics: Animals; Behavior, Animal; Body Weight; Diazepam; Discrimination Learning; Female; Gestational Age; | 1984 |
[Use of diazepam for medication of feed for pigs].
Topics: Animal Feed; Animals; Behavior, Animal; Body Weight; Diazepam; Hydroxycorticosteroids; Swine | 1980 |
Prolongation of drug half-life due to obesity: studies of desmethyldiazepam (clorazepate).
Topics: Adult; Aged; Body Weight; Clorazepate Dipotassium; Diazepam; Female; Half-Life; Humans; Male; Middle | 1982 |
Correlation of the bioavailability of diazepam from uncoated tablets in beagle dogs with its dissolution rate and bioavailability in humans.
Topics: Animals; Biological Availability; Body Weight; Diazepam; Dogs; Humans; Hydrogen-Ion Concentration; N | 1982 |
The effect of prenatal exposure to diazepam on aspects of postnatal development and behavior in rats.
Topics: Animals; Behavior, Animal; Body Weight; Diazepam; Discrimination Learning; Dose-Response Relationshi | 1982 |
Functional alterations in the hypothalamic-pituitary-thyroid axis in rats exposed prenatally to diazepam.
Topics: Animals; Body Weight; Diazepam; Female; Hypothalamo-Hypophyseal System; Male; Pregnancy; Prenatal Ex | 1983 |
The effects of chronic diazepam treatment on body weight and food intake in rats.
Topics: Analysis of Variance; Animals; Body Weight; Diazepam; Eating; Female; Male; Pregnancy; Rats; Rats, I | 1983 |
Influence of liver enzyme induction caused by diphenylhydantoin and diazepam on bone mass of rats.
Topics: Animals; Body Weight; Bone and Bones; Bone Development; Calcium; Diazepam; Enzyme Induction; Glucari | 1980 |
Oral administration of diazepam and promazine hydrochloride to immobilize pronghorn.
Topics: Administration, Oral; Animals; Antelopes; Artiodactyla; Body Weight; Diazepam; Dose-Response Relatio | 1982 |
Effect of valium (diazepam) on experimental atherosclerosis in roosters.
Topics: Animals; Aorta; Arteriosclerosis; Body Weight; Chickens; Cholesterol; Coronary Disease; Coronary Ves | 1982 |
Long-term effects of diazepam on plasma lipids and atheroma in roosters fed in atherogenic diet.
Topics: Animals; Aortic Diseases; Arteriosclerosis; Blood Pressure; Body Weight; Cholesterol; Coronary Disea | 1980 |
Effect of diazepam (Valium) on chronic stress-induced hypertension in the rat.
Topics: Animals; Blood Pressure; Body Weight; Diazepam; Disease Models, Animal; Hypertension; Male; Rats; St | 1981 |
Diazepam disposition determinants.
Topics: Adult; Age Factors; Aged; Body Weight; Diazepam; Female; Humans; Kinetics; Male; Metabolic Clearance | 1980 |
[The interaction of sedativa with etidocaine in patients with brachial plexus block (author's transl)].
Topics: Acetanilides; Adolescent; Adult; Barbiturates; Body Weight; Brachial Plexus; Diazepam; Drug Interact | 1980 |
Cardiac hypertrophy secondary to status epilepticus in the rat.
Topics: Animals; Body Weight; Cardiomegaly; Diazepam; Dizocilpine Maleate; Electroencephalography; Lithium C | 1995 |
Effects of early chronic diazepam treatment on incorporation of glucose and beta-hydroxybutyrate into cerebral amino acids: relation to undernutrition.
Topics: 3-Hydroxybutyric Acid; Amino Acids; Animals; Animals, Suckling; Blood Glucose; Body Weight; Brain; D | 1994 |
Effects of early protein malnutrition and environmental stimulation upon the reactivity to diazepam in two animal models of anxiety.
Topics: Animals; Anxiety; Behavior, Animal; Body Weight; Darkness; Diazepam; Diet; Environment; Handling, Ps | 1994 |
Diazepam withdrawal: effects of diazepam and gepirone on acoustic startle-induced 22 kHz ultrasonic vocalizations.
Topics: Acoustic Stimulation; Analgesics; Animals; Anti-Anxiety Agents; Body Temperature; Body Weight; Diaze | 1994 |
Effects of repeated intravenous administration of diazepam on food intake in rats.
Topics: Animals; Body Weight; Darkness; Diazepam; Dose-Response Relationship, Drug; Eating; Hyperphagia; Inf | 1994 |
Gender differences in diazepam withdrawal syndrome in mice.
Topics: Animals; Body Weight; Castration; Diazepam; Disease Models, Animal; Estrogens; Female; Flumazenil; I | 1994 |
Intravenous anesthetic induction in small animal patients.
Topics: Anesthesia, Intravenous; Animals; Body Weight; Diazepam; Ketamine; Thiopental | 1994 |
Potentiation of physical dependence on diazepam by ondansetron in rats.
Topics: Animals; Body Weight; Diazepam; Drug Synergism; Male; Ondansetron; Rats; Rats, Inbred F344; Substanc | 1994 |
The tolerometer: a fast, automated method for the measurement of righting reflex latency in chronic drug studies.
Topics: Amplifiers, Electronic; Animals; Body Weight; Diazepam; Drug Tolerance; Guinea Pigs; Microcomputers; | 1993 |
Effects of nifedipine on physical dependence on barbital or diazepam in rats.
Topics: Analysis of Variance; Animals; Barbital; Body Weight; Calcium Channel Blockers; Calcium Channels; Di | 1995 |
Reciprocal effects of chronic diazepam and melatonin on brain melatonin and benzodiazepine binding sites.
Topics: Animals; Body Weight; Brain; Cerebral Cortex; Diazepam; Flumazenil; Flunitrazepam; Kinetics; Male; M | 1996 |
A nonbenzodiazepine partial agonist, S-(+)-DN-2327, has minimal physical dependence-producing liability, but shows cross-dependence on barbital in rats.
Topics: Animals; Anti-Anxiety Agents; Area Under Curve; Barbital; Behavior, Animal; Binding, Competitive; Bo | 1996 |
Effect of restraint stress on feeding behavior of rats.
Topics: Animals; Anti-Anxiety Agents; Appetite; Body Weight; Diazepam; Fasting; Feeding Behavior; Male; Rats | 1997 |
Reproductive toxicology. Diazepam.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Birth Weight; Body Weight; Diazepam; Dose-Response Re | 1997 |
The effect of diazepan and exercise training on selected biochemical and histochemical properties of rat skeletal muscle.
Topics: Analysis of Variance; Animals; Body Weight; Calcium; Diazepam; Fructokinases; Male; Microsomes; Musc | 1997 |
The effect of chronic benzodiazepines exposure on body weight in rats.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Body Weight; Diazepam; Dose-Response Relationshi | 1998 |
Diazepam-treated female rats: flumazenil- and PK 11195-induced withdrawal in the hippocampus CA1.
Topics: Animals; Anti-Anxiety Agents; Body Weight; Diazepam; Dose-Response Relationship, Drug; Electroenceph | 1998 |
Long-term effects of early diazepam exposure on social differentiation in adult male rats subjected to the diving-for-food situation.
Topics: Animals; Anticonvulsants; Behavior, Animal; Body Weight; Conditioning, Operant; Diazepam; Food Depri | 1998 |
Prenatal stress induces body weight deficit and behavioural alterations in rats: the effect of diazepam.
Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Avoidance Learning; Behavior, Animal; Birth Weight; | 1999 |
Effects of prenatal diazepam treatment on Mycobacterium bovis-induced infection in hamsters.
Topics: Animals; Anti-Anxiety Agents; Body Weight; Cricetinae; Diazepam; Dose-Response Relationship, Drug; F | 1999 |
Severe symptoms following a massive intentional L-thyroxine ingestion.
Topics: Adult; Antidotes; Body Weight; Charcoal; Diazepam; Haloperidol; Humans; Intubation, Intratracheal; M | 1999 |
Some studies on the rodenticidal action of indomethacin.
Topics: Administration, Oral; Animals; Bile Ducts; Body Weight; Cholestyramine Resin; Diazepam; Drug Interac | 1999 |
Precipitated withdrawal in the substantia nigra in diazepam-dependent female rats.
Topics: Animals; Anti-Anxiety Agents; Body Weight; Diazepam; Electroencephalography; Female; Flumazenil; GAB | 1999 |
Anticonvulsant treatment of nerve agent seizures: anticholinergics versus diazepam in soman-intoxicated guinea pigs.
Topics: Animals; Anticonvulsants; Avoidance Learning; Body Weight; Chemical Warfare Agents; Cholinergic Anta | 2000 |
Diazepam has no beneficial effects on stress-induced behavioural and endocrine changes in male tree shrews.
Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Behavior, Animal; Body Weight; Diazepam; Hypothala | 2000 |
Diazepam-like effects of a fish protein hydrolysate (Gabolysat PC60) on stress responsiveness of the rat pituitary-adrenal system and sympathoadrenal activity.
Topics: Administration, Inhalation; Adrenocorticotropic Hormone; Animals; Anti-Anxiety Agents; Body Weight; | 2000 |
The effect of PK 11 195, a specific antagonist of the peripheral benzodiazepine receptors, on body weight in rats chronically exposed to diazepam.
Topics: Animals; Anti-Anxiety Agents; Body Weight; Diazepam; Female; GABA-A Receptor Antagonists; Isoquinoli | 2000 |
The pharmacodynamics of PK 11195 in diazepam-dependent male and female rats.
Topics: Animals; Anti-Anxiety Agents; Antineoplastic Agents; Body Weight; Brain; Diazepam; Female; Flumazeni | 2000 |
Analysis of respiratory mechanics by impulse oscillometry in non-sedated and diazepam-sedated swine.
Topics: Age Factors; Animals; Body Weight; Circadian Rhythm; Diazepam; Hypnotics and Sedatives; Oscillometry | 2001 |
Evidence for the role of brain norepinephrine and dopamine in "rebound" phenomenon seen during withdrawal after repeated exposure to benzodiazepines.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anti-Anxiety Agents; Body Weight; Brain; Brain Chemistry; B | 1977 |
Pharmacokinetics of N-desmethyldiazepam in healthy volunteers after single daily doses of dipotassium chlorazepate.
Topics: Adult; Anti-Anxiety Agents; Body Weight; Clorazepate Dipotassium; Diazepam; Drug Interactions; Femal | 1977 |
Plasma corticosterone responses to stress following chronic oral administration of diazepam in the rat.
Topics: Animals; Body Weight; Corticosterone; Diazepam; Electroshock; Feeding Behavior; Female; Humans; Immo | 1979 |
Effects of antipsychotic and antianxiety drugs on the morphine abstinence syndrome in rats.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Behavior, Animal; Body Weight; Chlordiazepoxide; | 1979 |
[Experimental study on development of physical dependence on alcohol and cross physical dependence liability of diazepam and barbital to alcohol in rhesus monkeys (author's transl)].
Topics: Alcoholism; Animals; Barbital; Barbiturates; Body Weight; Diazepam; Female; Haplorhini; Humans; Maca | 1978 |
Porcine malignant hyperthermia: effects of halothane on mitochondrial respiration and calcium accumulation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Body Weight; Calcium; | 1975 |
Metabolic level and limiting hypoxia in rodents.
Topics: Amphetamine; Animals; Body Temperature; Body Weight; Chinchilla; Diazepam; Dinitrophenols; Dose-Resp | 1975 |
Cholecystokinin, amphetamine and diazepam and feeding in lean and obese Zucker rats.
Topics: Animals; Body Weight; Cholecystokinin; Dextroamphetamine; Diazepam; Drug Interactions; Feeding Behav | 1979 |
Prevention by diazepam of adverse effects of maternal restraint stress on postnatal development and learning in the rat.
Topics: Animals; Body Weight; Corticosterone; Diazepam; Female; Growth; Learning; Pregnancy; Pregnancy Compl | 1979 |
A study on diazepam and postwithdrawal drinking of ethanol solution in rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Body Weight; Diazepam; Feeding Behavior; Humans; Male; Rats; | 1979 |
Factors influencing diazepam pharmacokinetics: age, sex, and liver disease.
Topics: Adult; Aged; Aging; Body Weight; Diazepam; Female; Galactose; Humans; Kinetics; Liver Diseases; Male | 1978 |
Abrupt withdrawal from therapeutically administered diazepam. Report of a case.
Topics: Adult; Anxiety; Behavior; Body Weight; Diazepam; Emotions; Humans; Male; Pulse; Substance Withdrawal | 1978 |
[Physiopathological concepts on eclampsia (author's transl)].
Topics: Body Weight; Cesarean Section; Diazepam; Diet, Sodium-Restricted; Female; Furosemide; Humans; Hypert | 1978 |
Some effects of diazepam on pregnancy in the Balb/C mouse.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Anophthalmos; Body Weight; Diazepam; Ear | 1975 |
Attainment and stability of the performance in differential low rate water reinforcement in rats.
Topics: Animals; Behavior, Animal; Body Weight; Caffeine; Conditioning, Operant; Diazepam; Male; Methampheta | 1976 |
The effect of diazepam on performance and emotional response during viva examination [proceedings].
Topics: Body Weight; Diazepam; Educational Measurement; Heart Rate; Humans; Stress, Psychological | 1976 |
Teratogenicity of oral diazepam and diphenylhydantoin in mice.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Cleft Palate; Diazepam; Female; Fetal Death; Fetu | 1975 |
[Comparison of development of drug dependence in naive and drug dependence-experienced rats].
Topics: Administration, Oral; Animals; Body Weight; Chlordiazepoxide; Diazepam; Eating; Female; Humans; Male | 1975 |
[Effect of neurotropin on SART stress (stress caused by alteration of rhythms in environmental temperature) in mice and rats].
Topics: Acetylcholine; Aminobutyrates; Animals; Body Weight; Chlorpromazine; Diazepam; Diphenhydramine; Duod | 1975 |
[Dependence on and preference for morphine (II). Comparison among morphine, phenobarbital and diazepam].
Topics: Animals; Body Weight; Choice Behavior; Decision Making; Diazepam; Female; Humans; Male; Methods; Mor | 1975 |
Diazepam, ethanol and drug metabolizing enzymes in rat liver.
Topics: Aniline Compounds; Animals; Benzopyrene Hydroxylase; Body Weight; Cytochrome P-450 Enzyme System; Di | 1975 |
[Premedication in childhood].
Topics: Adolescent; Age Factors; Atropine; Benperidol; Body Weight; Child; Child, Preschool; Diazepam; Drug | 1975 |
Physical dependence on morphine, phenobarbital and diazepam in rats by drug-admixed food ingestion.
Topics: Animals; Body Weight; Diazepam; Diet; Feeding Behavior; Female; Humans; Levallorphan; Male; Morphine | 1975 |
Neurodevelopment in late infancy after prenatal exposure to benzodiazepines--a prospective study.
Topics: Abnormalities, Drug-Induced; Anti-Anxiety Agents; Arousal; Body Height; Body Weight; Cephalometry; D | 1992 |
Genetic differences in the development of physical dependence upon diazepam in Lewis and Fischer 344 inbred rat strains.
Topics: Animals; Body Weight; Diazepam; Eating; Growth; Male; Postural Balance; Psychomotor Performance; Rat | 1992 |
Effect of diazepam on the fatty acid composition of plasma and liver phospholipids in rat.
Topics: Animals; Body Weight; Diazepam; Fatty Acids; Liver; Male; Phospholipids; Rats; Rats, Inbred Strains | 1992 |
Effects of age and drugs on food and fluid intake.
Topics: Aging; Amphetamines; Animals; Behavior, Animal; Benzodiazepines; Body Weight; Diazepam; Drinking; Dr | 1991 |
Impact of prenatal low-dose diazepam or chlorpromazine on reflex and motor development and inhibitory-learning.
Topics: Animals; Animals, Newborn; Avoidance Learning; Behavior, Animal; Body Weight; Chlorpromazine; Condit | 1991 |
Diazepam and intubation in emergency treatment of seizures in children.
Topics: Adolescent; Body Weight; Case-Control Studies; Child; Child, Preschool; Diazepam; Drug Therapy, Comb | 1991 |
Early postnatal diazepam exposure alters sex differences in the rat brain.
Topics: Aging; Animals; Body Weight; Brain; Diazepam; Female; Locus Coeruleus; Male; Neurons; Olfactory Bulb | 1991 |
Physical and behavioral development in rats after late prenatal exposure to diazepam.
Topics: Amphetamine; Animals; Anticonvulsants; Avoidance Learning; Behavior, Animal; Body Temperature; Body | 1990 |
Decreased reactivity to anxiolytics caused by early protein malnutrition in rats.
Topics: Animals; Anti-Anxiety Agents; Body Weight; Diazepam; Diet; Dose-Response Relationship, Drug; Hyperto | 1990 |
Investigations with the novel non-opioid analgesic flupirtine in regard to possible benzodiazepine-like abuse inducing potential.
Topics: Aminopyridines; Analgesics; Animals; Anti-Anxiety Agents; Binding, Competitive; Body Weight; Brain C | 1990 |
Social behavior, dominance, and social deprivation of rats determine drug choice.
Topics: Animals; Behavior, Animal; Body Weight; Diazepam; Drinking; Eating; Ethanol; Male; Quinine; Rats; Ra | 1991 |
Substitution of psychoactive drugs in pentobarbital-dependent rats.
Topics: Animals; Antidepressive Agents; Arousal; Body Weight; Brain; Bromazepam; Bupropion; Diazepam; Dose-R | 1990 |
Prevention of immunosuppression in stressed mice by neurotropin(NSP).
Topics: Animals; Atropine; Body Weight; Cytotoxicity, Immunologic; Diazepam; Female; Immune Tolerance; Kille | 1990 |
Effects of acute administration of diazepam and d-amphetamine on aggressive and escape responding of normal male subjects.
Topics: Aggression; Avoidance Learning; Body Weight; Dextroamphetamine; Diazepam; Dose-Response Relationship | 1990 |
Appetite-modulating drugs in dwarf goats, with special emphasis on benzodiazepine-induced hyperphagia and its antagonism by flumazenil and RO 15-3505.
Topics: Animals; Anti-Anxiety Agents; Appetite Regulation; Azepines; Benzodiazepines; Benzodiazepinones; Bod | 1989 |
A large-sample study of diazepam pharmacokinetics.
Topics: Adolescent; Adult; Body Weight; Chromatography, Gas; Diazepam; Half-Life; Humans; Male; Nordazepam | 1989 |
[Muscular rigidity caused by alfentanil: prevention].
Topics: Adolescent; Adult; Age Factors; Alfentanil; Body Weight; Diazepam; Humans; Middle Aged; Muscle Rigid | 1989 |
Brain lipids in rat after chronic diazepam treatment.
Topics: Animals; Body Weight; Brain Chemistry; Diazepam; Galactose; Gangliosides; Glycolipids; Lipid Metabol | 1989 |
Atropine and/or diazepam therapy protects against soman-induced neural and cardiac pathology.
Topics: Animals; Atropine; Body Weight; Cholinesterase Inhibitors; Diazepam; Drug Interactions; Heart Diseas | 1989 |
Antidepressant properties of the triazolobenzodiazepines alprazolam and adinazolam: studies on the olfactory bulbectomized rat model of depression.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Biogenic Amines; B | 1985 |
Benzodiazepine dependence in mice after ingestion of drug-containing food pellets.
Topics: Aggression; Animals; Anti-Anxiety Agents; Body Weight; Diazepam; Eating; Male; Mice; Substance Withd | 1986 |
Effects of neuroleptics administered to lactating rats on the behavioral development of offspring.
Topics: Animals; Animals, Suckling; Antipsychotic Agents; Behavior, Animal; Body Weight; Diazepam; Female; G | 1986 |
The anxiolytic and anxiogenic actions of ethanol in a mouse model.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Body Weight; Clonidine; Diazepam; Drinking; | 1988 |
Periodic benzodiazepine antagonist administration prevents benzodiazepine withdrawal symptoms in primates.
Topics: Animals; Behavior, Animal; Body Weight; Diazepam; Drug Administration Schedule; Flumazenil; Macaca m | 1986 |
Lack of withdrawal signs of dependence following cessation of treatment or Ro-15,1788 administration to rats chronically treated with buspirone.
Topics: Animals; Body Weight; Buspirone; Diazepam; Flumazenil; Food Deprivation; Male; Pyrimidines; Rats; Ra | 1986 |
Effects of perphenazine, diazepam and nitrazepam on amitriptyline metabolism in rat.
Topics: Amitriptyline; Animals; Body Weight; Diazepam; Glucuronosyltransferase; Male; Microsomes, Liver; Nit | 1988 |
Carbamates, atropine, and diazepam: effects on performance in the running rat.
Topics: Animals; Atropine; Body Temperature; Body Weight; Diazepam; Male; Physical Endurance; Physical Exert | 1988 |
[Physical dependence liability test of 4-(o-benzylphenoxy)-N-methylbutylamine hydrochloride (MCI-2016) in rats].
Topics: Animals; Antidepressive Agents; Barbiturates; Benzhydryl Compounds; Body Weight; Codeine; Diazepam; | 1987 |
Prolonged and multiple immobilizations of the southern elephant seal using ketamine hydrochloride-xylazine hydrochloride or ketamine hydrochloride-diazepam combinations.
Topics: Anesthesia, General; Animals; Body Weight; Caniformia; Diazepam; Drug Combinations; Immobilization; | 1987 |
Tumor-promoting activity of benzodiazepine tranquilizers, diazepam and oxazepam, in mouse liver.
Topics: Aminopyrine N-Demethylase; Animals; Body Weight; Cocarcinogenesis; Cytochrome P-450 Enzyme System; D | 1986 |
Physical dependence capacity of brotizolam in rhesus monkeys. 2nd communication: primary dependence and barbital substitution.
Topics: Animals; Azepines; Barbital; Barbiturates; Body Weight; Diazepam; Female; Hypnotics and Sedatives; M | 1986 |
Effects of chronic alcohol intake on anesthetic responses to diazepam and thiopental in rats.
Topics: Alcoholism; Anesthesia, Intravenous; Animals; Body Weight; Diazepam; Drug Interactions; Drug Toleran | 1986 |
Effects of a chronic administration of two benzodiazepines on food intake in rats given a highly palatable diet.
Topics: Adipose Tissue; Animals; Azepines; Body Weight; Diazepam; Feeding Behavior; Food Preferences; Male; | 1986 |
Effects of combined administration of diazepam and imipramine hydrochloride in rats.
Topics: Animals; Body Weight; Diazepam; Enzymes; Imipramine; Kinetics; Male; Microsomes, Liver; Organ Size; | 1986 |
N-desmethyldiazepam physical dependence in dogs.
Topics: Analysis of Variance; Animals; Body Weight; Diazepam; Dogs; Drinking; Energy Intake; Female; Lorazep | 1985 |
Age-dependent enhancement of diazepam sensitivity is accelerated in New Zealand Black mice.
Topics: Aging; Animals; Ataxia; Barbiturates; Body Weight; Diazepam; Dose-Response Relationship, Drug; Male; | 1986 |
Behavioural supersensitivity to apomorphine following chronic treatment with drugs which interfere with the synaptic function of catecholamines.
Topics: Animals; Apomorphine; Behavior, Animal; Body Weight; Catecholamines; Chlorpromazine; Diazepam; Dose- | 1974 |
Newborn infants of mothers on methadone maintenance.
Topics: Body Weight; Camphor; Diazepam; Female; Gestational Age; Humans; Infant, Newborn; Infant, Newborn, D | 1974 |
Review of 12 months' treatment with L-dopa in Parkinson's disease, with remarks on unusual side effects.
Topics: Adult; Aged; Atrial Flutter; Body Weight; Deglutition Disorders; Diazepam; Dihydroxyphenylalanine; D | 1972 |
[Tolerance and physical dependence producing liability of doxepin].
Topics: Amitriptyline; Animals; Body Weight; Diazepam; Dibenzoxepins; Drug Resistance; Humans; Imipramine; M | 1972 |
Effectiveness of diazepam and methylphenidate in multiple dosages in modifying infant trauma effects.
Topics: Animals; Animals, Newborn; Avoidance Learning; Body Weight; Conditioning, Classical; Diazepam; Dose- | 1973 |
[Screening procedure for barbital type physical dependence liability of psychotropic drugs in mice].
Topics: Amitriptyline; Animals; Barbiturates; Behavior, Animal; Benzazepines; Benzodiazepinones; Body Weight | 1973 |
Practical pharmacokinetic techniques for drug consultation and evaluation. 3. Psychotherapeutic drugs as prototypes for illustrating some considerations in pharmacist-generated dosage regimens.
Topics: Body Weight; Chlorpromazine; Diazepam; Dose-Response Relationship, Drug; Drug Evaluation; Half-Life; | 1974 |
[Smoking habits and smoking withdrawal in Swiss men].
Topics: Adolescent; Adult; Age Factors; Aged; Blood Pressure; Body Weight; Bronchitis; Cardiovascular Diseas | 1974 |
A comparison of baclofen and diazepam in the treatment of spasticity.
Topics: Adult; Aminobutyrates; Body Weight; Chlorine; Diazepam; Female; Humans; Male; Middle Aged; Multiple | 1974 |
Postpartum tubal ligation under local anesthesia.
Topics: Adult; Alphaprodine; Anesthesia, Local; Body Weight; Diazepam; Fallopian Tubes; Female; Humans; Inje | 1972 |
[Premedication for dental surgery in local anesthesia and laughing gas analgesia].
Topics: Adolescent; Adult; Age Factors; Aged; Analgesia; Anesthesia, Dental; Anesthesia, Inhalation; Anesthe | 1971 |
Metabolism of 14C-medazepam hydrochloride in dog, rat and man.
Topics: Adipose Tissue; Administration, Oral; Animals; Benzazepines; Biotransformation; Body Weight; Brain C | 1970 |
[Prevention and treatment of eclampsic symptom-complex].
Topics: Apgar Score; Bilirubin; Blood Gas Analysis; Body Weight; Diazepam; Eclampsia; Electroencephalography | 1970 |
The pharmacology and toxicology of midaflur.
Topics: Analgesics; Animals; Appetite; Avoidance Learning; Benzimidazoles; Body Temperature; Body Weight; Ca | 1971 |
[The effect of diazepam (Valium) on the saccadic eye movements in man].
Topics: Adult; Body Weight; Diazepam; Electroretinography; Eye Movements; Humans; Injections, Intravenous; T | 1968 |