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diazepam and Bipolar Disorder

diazepam has been researched along with Bipolar Disorder in 45 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

Research Excerpts

ExcerptRelevanceReference
"The purpose of the present paper was to remind physicians that hypothermia is a possible side-effect of combining zotepine, valproate,and benzodiazepine."7.72Two case studies of hypothermia induced by an increased dosage of zotepine in a combination therapy. ( Chen, KC; Chen, PS; Yang, MJ; Yang, YK; Yeh, TL, 2003)
"He also had visual hallucinations and temporary high blood pressure."5.37Pharmacoresistant convulsions and visual hallucinations around two weeks after selegiline overdose: a case report. ( Kato, S; Kobayashi, T; Saito, N; Shioda, K; Suda, S, 2011)
"Patients with catatonia who had more than one episode of catatonia and were treated with the lorazepam-diazepam protocol were identified."3.83Relapses and recurrences of catatonia: 30-case analysis and literature review. ( Huang, TL; Hung, YY; Lin, CC; Tsai, MC, 2016)
"The purpose of the present paper was to remind physicians that hypothermia is a possible side-effect of combining zotepine, valproate,and benzodiazepine."3.72Two case studies of hypothermia induced by an increased dosage of zotepine in a combination therapy. ( Chen, KC; Chen, PS; Yang, MJ; Yang, YK; Yeh, TL, 2003)
" In 37 patients with anxiety depression the DST was combined with the diazepam test."3.67[Use of the dexamethasone test in the differential diagnosis of depressive states]. ( Gordon, OI; Nuller, IuL; Ostroumova, MN, 1986)
"A fatal pancytopenia occurred in a patient with an history of depression with hypomanic rebounds, admitted for a manic episode and treated with levomepromazine, diazepam and lithium carbonate."3.65A fatal case of pancytopenia due to levomepromazine. ( Burti, L; Garzotto, N; Tansella, M, 1976)
"Diazepam was given intravenously to the patients at a rate of 5 mg per 30 seconds."2.70Immediate effect of intravenous diazepam in neuroleptic-induced acute akathisia: an open-label study. ( Ashby, CR; Hirose, S, 2002)
"He also had visual hallucinations and temporary high blood pressure."1.37Pharmacoresistant convulsions and visual hallucinations around two weeks after selegiline overdose: a case report. ( Kato, S; Kobayashi, T; Saito, N; Shioda, K; Suda, S, 2011)
"This is a report of a jacksonian seizure in a non-psychotic manic patient who was treated with right prefrontal high frequency rTMS concomitant to pharmacotherapy."1.35Jacksonian seizure in a manic patient treated with rTMS. ( Papadimitriou, GN; Psarros, C; Sakkas, P; Soldatos, CR; Theleritis, CG, 2008)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199032 (71.11)18.7374
1990's6 (13.33)18.2507
2000's4 (8.89)29.6817
2010's2 (4.44)24.3611
2020's1 (2.22)2.80

Authors

AuthorsStudies
Osler, M1
Jørgensen, MB1
Lin, CC1
Hung, YY1
Tsai, MC1
Huang, TL1
Kobayashi, T1
Saito, N1
Suda, S1
Shioda, K1
Kato, S1
Atmaca, M1
Kuloglu, M1
Buyukbayram, A1
Tezcan, E1
Chen, KC1
Yang, YK1
Chen, PS1
Yeh, TL1
Yang, MJ1
POELDINGER, W1
INVERNIZZI, G1
GOLD, RL1
DRIBBEN, IS1
DEAN, SR1
Sakkas, P1
Theleritis, CG1
Psarros, C1
Papadimitriou, GN1
Soldatos, CR1
Nuller, JL1
Tochilov, VA1
Shirokov, VD1
Chouinard, G1
Labonte, A1
Fontaine, R1
Annable, L1
Emrich, HM1
Altmann, H1
Dose, M1
von Zerssen, D1
Post, RM1
Uhde, TW1
Louis, ED1
Pflaster, NL1
Rosebush, PI1
Mazurek, MF1
Hirose, S1
Ashby, CR1
Lerner, Y1
Lwow, E1
Levitin, A1
Belmaker, RH1
Garzotto, N1
Burti, L1
Tansella, M1
Sheehan, MF1
Sheehan, DV1
Torres, A1
Coppola, A1
Francis, E1
Mitchell, P1
Smythe, G1
Ghaziuddin, N1
Ghaziuddin, M1
Swartz, CM1
Schnetzler, JP1
Préaubert, G1
Schnetzler, F1
Molnar, G1
Fava, GA1
Zielezny, M1
Spinks, MT1
Loretan, A1
Nuller, YL1
Nuller, IuL1
Ostroumova, MN1
Gordon, OI1
Raskin, A1
Schulterbrandt, JG1
Reatig, N1
Crook, TH1
Odle, D1
Franck, G1
Zsadányi, O1
Molnár, C1
King, DJ1
Deberdt, R1
Karno, M1
Sakurai, T1
Nishizono, M1
Noiri, T1
Kammerer, M1
Wartel, R1
Gurfein, L1
Weil, J1
Wysoki, V1
Gelb, F1
Angst, J1
Dale, J1
Fracchia, J1
Sheppard, C1
Merlis, S1
Korczyn, AD1
Goldberg, GJ1
Arnold, OH1
Heves, HP1
Wolpowitz, B1
Roux, JT1
McLaughlin, BE1
Aleksandrovskiĭ, IuA1
Langner, E1

Reviews

4 reviews available for diazepam and Bipolar Disorder

ArticleYear
Treatment of mood disorders with antiepileptic medications: clinical and theoretical implications.
    Epilepsia, 1983, Volume: 24 Suppl 2

    Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Clonazepam; Depressive D

1983
[A valproic acid-diazepam combination as an alternative to neuroleptic treatment].
    Annales medico-psychologiques, 1988, Volume: 146, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Bipolar Disorder; Diazepam; Drug Combinations; Female; Humans; Male;

1988
[Recent developments in psychopharmacology].
    Praxis, 1968, Feb-06, Volume: 57, Issue:5

    Topics: Antidepressive Agents; Barbiturates; Bipolar Disorder; Chlormethiazole; Depression; Diazepam; Electr

1968
[Psychopharmacological agent in anxiety states].
    Nordisk medicin, 1970, Feb-19, Volume: 83, Issue:8

    Topics: Antidepressive Agents; Anxiety Disorders; Bipolar Disorder; Depression; Diazepam; Humans; Psychother

1970

Trials

10 trials available for diazepam and Bipolar Disorder

ArticleYear
New concepts in benzodiazepine therapy: rebound anxiety and new indications for the more potent benzodiazepines.
    Progress in neuro-psychopharmacology & biological psychiatry, 1983, Volume: 7, Issue:4-6

    Topics: Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Bipolar Disorder; Bromazepam; C

1983
Therapeutic effects of GABA-ergic drugs in affective disorders. A preliminary report.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:2

    Topics: Adolescent; Adult; Analgesics; Anticonvulsants; Bipolar Disorder; Carbamazepine; Clinical Trials as

1983
Treatment of mood disorders with antiepileptic medications: clinical and theoretical implications.
    Epilepsia, 1983, Volume: 24 Suppl 2

    Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Clonazepam; Depressive D

1983
Immediate effect of intravenous diazepam in neuroleptic-induced acute akathisia: an open-label study.
    The Journal of clinical psychiatry, 2002, Volume: 63, Issue:6

    Topics: Acute Disease; Adult; Akathisia, Drug-Induced; Anti-Anxiety Agents; Antipsychotic Agents; Bipolar Di

2002
Acute high-dose parenteral haloperidol treatment of psychosis.
    The American journal of psychiatry, 1979, Volume: 136, Issue:8

    Topics: Acute Disease; Adult; Bipolar Disorder; Blood Pressure; Clinical Trials as Topic; Diazepam; Dose-Res

1979
Depression subtypes and response to phenelzine, diazepam, and a placebo. Results of a nine hospital collaborative study.
    Archives of general psychiatry, 1974, Volume: 30, Issue:1

    Topics: Adolescent; Adult; Anxiety; Bipolar Disorder; Clinical Trials as Topic; Depression; Diazepam; Drug E

1974
[Hypnotic effect of Nitrazepam, a new benzodiazepine derivative].
    No to shinkei = Brain and nerve, 1967, Volume: 19, Issue:11

    Topics: Bipolar Disorder; Clinical Trials as Topic; Diazepam; Humans; Hypnotics and Sedatives; Neurotic Diso

1967
[Clinical experimentation with desipramine with statistical control].
    Annales medico-psychologiques, 1968, Volume: 1, Issue:1

    Topics: Adult; Aged; Anorexia Nervosa; Barbiturates; Bipolar Disorder; Chlordiazepoxide; Chlorpromazine; Cli

1968
Combination medications in psychiatric treatment: patterns in a group of elderly hospital patients.
    Journal of the American Geriatrics Society, 1971, Volume: 19, Issue:4

    Topics: Age Factors; Aged; Amitriptyline; Antidepressive Agents; Antihypertensive Agents; Antisocial Persona

1971
[The treatment of endogenous depression with monochlorimipramin].
    Wiener klinische Wochenschrift, 1967, Jan-06, Volume: 79, Issue:1

    Topics: Amitriptyline; Antidepressive Agents; Bipolar Disorder; Chlordiazepoxide; Clinical Trials as Topic;

1967

Other Studies

32 other studies available for diazepam and Bipolar Disorder

ArticleYear
Associations of Benzodiazepines, Z-Drugs, and Other Anxiolytics With Subsequent Dementia in Patients With Affective Disorders: A Nationwide Cohort and Nested Case-Control Study.
    The American journal of psychiatry, 2020, 06-01, Volume: 177, Issue:6

    Topics: Aged; Aged, 80 and over; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Azabicycl

2020
Relapses and recurrences of catatonia: 30-case analysis and literature review.
    Comprehensive psychiatry, 2016, Volume: 66

    Topics: Adolescent; Adult; Antipsychotic Agents; Bipolar Disorder; Catatonia; Clozapine; Depressive Disorder

2016
Pharmacoresistant convulsions and visual hallucinations around two weeks after selegiline overdose: a case report.
    Pharmacopsychiatry, 2011, Volume: 44, Issue:7

    Topics: Anticonvulsants; Bipolar Disorder; Coma; Diazepam; Drug Overdose; Drug Resistance; Hallucinations; H

2011
Quetiapine-associated and dose-related hypomania in a woman with schizophrenia.
    European psychiatry : the journal of the Association of European Psychiatrists, 2002, Volume: 17, Issue:5

    Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Diazepam; Dibenzothiazepines; Dose-Response Relations

2002
Two case studies of hypothermia induced by an increased dosage of zotepine in a combination therapy.
    Psychiatry and clinical neurosciences, 2003, Volume: 57, Issue:4

    Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Diazepam; Diben

2003
[CLINICAL EXPERIENCES WITH THE LIBRIUM ANALOGUE RO 5-2807 (VALIUM) IN PSYCHOTIC STATES].
    Schweizer Archiv fur Neurologie, Neurochirurgie und Psychiatrie = Archives suisses de neurologie, neurochirurgie et de psychiatrie, 1963, Volume: 92

    Topics: Bipolar Disorder; Chlordiazepoxide; Diazepam; Humans; Intellectual Disability; Mental Disorders; Par

1963
[OBSERVATIONS ON THE USE OF PHENYLPYRROLIDINOPENTANE AS AN ANTIASTHENIC AGENT IN TREATMENT WITH PSYCHOPHARMACOLOGICAL DRUGS].
    Gazzetta medica italiana, 1964, Volume: 123

    Topics: Amitriptyline; Anxiety; Anxiety Disorders; Asthenia; Bipolar Disorder; Chemical and Drug Induced Liv

1964
DIAZEPAM THERAPY OF DEPRESSED PATIENTS.
    Journal of neuropsychiatry, 1964, Volume: 5

    Topics: Bipolar Disorder; Chlordiazepoxide; Depression; Depressive Disorder; Depressive Disorder, Major; Dia

1964
DIAZEPAM AS AN ADJUVANT IN PSYCHOTHERAPY.
    The American journal of psychiatry, 1964, Volume: 121

    Topics: Adolescent; Anxiety; Bipolar Disorder; Depression; Depressive Disorder, Major; Diazepam; Drug Therap

1964
Jacksonian seizure in a manic patient treated with rTMS.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2008, Volume: 9, Issue:2

    Topics: Adult; Anticonvulsants; Bipolar Disorder; Diazepam; Electroencephalography; Female; Humans; Seizures

2008
The use of a diazepam test for the study of depressive state structure and for choice of therapy.
    Biological psychiatry, 1982, Volume: 17, Issue:7

    Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Bipolar Disorder;

1982
Catatonia mimicking nonconvulsive status epilepticus.
    Epilepsia, 1995, Volume: 36, Issue:9

    Topics: Adult; Benzodiazepines; Bipolar Disorder; Catatonia; Diagnosis, Differential; Diazepam; Electroencep

1995
Do benzodiazepines modify the incidence of neuroleptic-induced dystonia?
    The American journal of psychiatry, 1993, Volume: 150, Issue:3

    Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Diazepam; Dystonia; Humans; Schizophrenia

1993
A fatal case of pancytopenia due to levomepromazine.
    The British journal of psychiatry : the journal of mental science, 1976, Volume: 129

    Topics: Adult; Bipolar Disorder; Diazepam; Drug Interactions; Drug Therapy, Combination; Female; Humans; Lit

1976
Snorting benzodiazepines.
    The American journal of drug and alcohol abuse, 1991, Volume: 17, Issue:4

    Topics: Administration, Intranasal; Adult; Alprazolam; Anti-Anxiety Agents; Arousal; Bipolar Disorder; Diaze

1991
Hormonal responses to fenfluramine in depressed and control subjects.
    Journal of affective disorders, 1990, Volume: 19, Issue:1

    Topics: Adult; Bipolar Disorder; Depressive Disorder; Diazepam; Female; Fenfluramine; Humans; Hydrocortisone

1990
Mania-like reaction induced by benzodiazepine withdrawal in a patient with mental retardation.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1990, Volume: 35, Issue:7

    Topics: Adult; Bipolar Disorder; Diazepam; Dose-Response Relationship, Drug; Drug Administration Schedule; F

1990
Electroconvulsive therapy emergence agitation and succinylcholine dose.
    The Journal of nervous and mental disease, 1990, Volume: 178, Issue:7

    Topics: Adult; Akathisia, Drug-Induced; Bipolar Disorder; Depressive Disorder; Diazepam; Dose-Response Relat

1990
Measurement of subclinical changes during lithium prophylaxis: a longitudinal study.
    Psychopathology, 1987, Volume: 20, Issue:3-4

    Topics: Adult; Amitriptyline; Bipolar Disorder; Chlordiazepoxide; Diazepam; Drug Therapy, Combination; Femal

1987
Classification and treatment of endogenous depressions.
    Current psychiatric therapies, 1986, Volume: 23

    Topics: Affective Disorders, Psychotic; Antidepressive Agents; Anxiety; Bipolar Disorder; Dexamethasone; Dia

1986
[Use of the dexamethasone test in the differential diagnosis of depressive states].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1986, Volume: 86, Issue:4

    Topics: 11-Hydroxycorticosteroids; Adolescent; Adult; Aged; Anxiety; Bipolar Disorder; Depression; Depressiv

1986
[A new original antidepressant derivative of dibenzodiazepine].
    Annales medico-psychologiques, 1966, Volume: 124, Issue:2

    Topics: Antidepressive Agents; Bipolar Disorder; Central Nervous System Stimulants; Depression; Diazepam; Hu

1966
[Neuro-psychiatric symptomatology in hypoglycemia].
    Revue medicale de Liege, 1974, Apr-15, Volume: 29, Issue:8

    Topics: Adenoma; Adult; Alcohol Drinking; Atropine; Bipolar Disorder; Coma; Diabetes Complications; Diazepam

1974
Electroencephalographic analysis of atropine coma.
    Acta physiologica Academiae Scientiarum Hungaricae, 1972, Volume: 41, Issue:1

    Topics: Atropine; Barbiturates; Bipolar Disorder; Coma; Delirium; Diazepam; Electroencephalography; Epilepsy

1972
Plasma cortisol-binding capacity in mental illness.
    Psychological medicine, 1973, Volume: 3, Issue:1

    Topics: Adult; Anxiety; Binding Sites; Bipolar Disorder; Chlorpromazine; Chromatography, Gel; Depression; Di

1973
Lorazepam in the treatment of severe anxiety and anxiety associated with psychotic conditions.
    Current medical research and opinion, 1973, Volume: 1, Issue:5

    Topics: Adult; Aggression; Amitriptyline; Anxiety Disorders; Ataxia; Benzodiazepinones; Bipolar Disorder; Ch

1973
The care of psychotic patients.
    American family physician, 1974, Volume: 9, Issue:1

    Topics: Adult; Affective Symptoms; Ambulatory Care; Anxiety; Bipolar Disorder; Brain Damage, Chronic; Diazep

1974
Intravenous diazepam in drug-induced dystonic reactions.
    The British journal of psychiatry : the journal of mental science, 1972, Volume: 121, Issue:560

    Topics: Adult; Bipolar Disorder; Butyrophenones; Diazepam; Female; Humans; Injections, Intravenous; Male; Mi

1972
[Parenteral treatment of depressive diseases].
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1970, Oct-10, Volume: 44, Issue:40

    Topics: Antidepressive Agents; Bipolar Disorder; Dementia; Depression; Depressive Disorder, Major; Desiprami

1970
Unexpected failure of a satisfactory anti-depressive drug routine to control hostile expression in psychiatric out-patients.
    Diseases of the nervous system, 1970, Volume: 31

    Topics: Adjustment Disorders; Ambulatory Care; Antidepressive Agents; Anxiety; Bipolar Disorder; Chlordiazep

1970
[The basic criteria for clinical evaluation of the effect of tranquilizers].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1970, Volume: 70, Issue:12

    Topics: Benactyzine; Bipolar Disorder; Central Nervous System Diseases; Chlordiazepoxide; Diazepam; Epilepsy

1970
[Management of psychotic drive disorders].
    Wiener medizinische Wochenschrift (1946), 1968, Sep-07, Volume: 118, Issue:36

    Topics: Adult; Bipolar Disorder; Chlorprothixene; Diazepam; Drive; Female; Fluphenazine; Humans; Imipramine;

1968