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diazepam and Benign Neoplasms

diazepam has been researched along with Benign Neoplasms in 26 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Research Excerpts

ExcerptRelevanceReference
"We conducted an evaluation of the usefulness of antiemetics (5-Hydroxy-tryptamine 3 receptor antagonism, 5HT3RA) combined with diazepam for delayed nausea and vomiting due to anticancer agents in 17 patients with various malignancies (such as lung Ca, breast Ca, esophagus Ca, gastric Ca, colon Ca, and non Hodgkin's disease) for whom chemotherapy was performed with different regimens in the Dept."9.08[Effect of diazepam on delayed nausea and vomiting caused by anticancer agents]. ( Hong, J; Hui, S; Liu, HJ; Mao, YC; Meng, FY; Qiao, XM; Shu, W; Tong, FZ; Zhang, JQ; Zhu, FX, 1998)
"To report 2 cases of nonconvulsive status epilepticus (NCSE) following infusion of ifosfamide."7.73Nonconvulsive status epilepticus due to ifosfamide. ( Akoglu, H; Aksoy, S; Cakar, M; Erman, M; Kilickap, S; Onal, IK; Tekuzman, G; Tufan, A, 2006)
" Comparison of anti-anxiety and antidepressant effects of alprazolam and diazepam in patients treated with systemic chemotherapy."5.11[Evaluation of the usefulness and effectiveness of anxiolytic therapies in neoplastic diseases]. ( Bucior, J; Foltyn, W; Jastrzebska-Okoń, K; Kempiński, M; Knopik, J; Tomczyk, A; Ziółko, E, 2004)
"We conducted an evaluation of the usefulness of antiemetics (5-Hydroxy-tryptamine 3 receptor antagonism, 5HT3RA) combined with diazepam for delayed nausea and vomiting due to anticancer agents in 17 patients with various malignancies (such as lung Ca, breast Ca, esophagus Ca, gastric Ca, colon Ca, and non Hodgkin's disease) for whom chemotherapy was performed with different regimens in the Dept."5.08[Effect of diazepam on delayed nausea and vomiting caused by anticancer agents]. ( Hong, J; Hui, S; Liu, HJ; Mao, YC; Meng, FY; Qiao, XM; Shu, W; Tong, FZ; Zhang, JQ; Zhu, FX, 1998)
"To report 2 cases of nonconvulsive status epilepticus (NCSE) following infusion of ifosfamide."3.73Nonconvulsive status epilepticus due to ifosfamide. ( Akoglu, H; Aksoy, S; Cakar, M; Erman, M; Kilickap, S; Onal, IK; Tekuzman, G; Tufan, A, 2006)
"Nausea and vomiting are frequent and unpleasant side effects of cancer chemotherapy."2.36[Nausea and vomiting during chemotherapy of malignant tumors]. ( Brunner, KW; Galeazzi, R; Gervasi, A; Godat, F; Goldhirsch, A; Joss, R, 1981)
"Psychotropic agents can promote tumors and inhibit neoplastic cell growth."1.27[Psychopharmaceuticals and cancer. Modification of tumor growth by psychoactive drugs]. ( Jäger, H, 1984)
"Diazepam has the characteristics of a tumour promoter in a number of in vitro systems."1.26The possible effect of diazepam on cancer development and growth. ( Horrobin, DF; Trosko, JE, 1981)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199017 (65.38)18.7374
1990's4 (15.38)18.2507
2000's3 (11.54)29.6817
2010's2 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hamed, MM1
Darwish, SS1
Herrmann, J1
Abadi, AH1
Engel, M1
Pifarré, P1
Simó, M1
Gispert, JD1
Plaza, P1
Fernández, A1
Pujol, J1
ROGERS, WK1
WATERMAN, DH1
DOMM, SE1
SUNAY, A1
Ziółko, E1
Knopik, J1
Bucior, J1
Foltyn, W1
Jastrzebska-Okoń, K1
Tomczyk, A1
Kempiński, M1
Gelfand, MJ1
O'hara, SM1
Curtwright, LA1
Maclean, JR1
Kilickap, S1
Cakar, M1
Onal, IK1
Tufan, A1
Akoglu, H1
Aksoy, S1
Erman, M1
Tekuzman, G1
Hindmarsh, KW1
LeGatt, DF1
Jackson, MR1
Harris, PA1
Joss, R1
Galeazzi, R1
Gervasi, A1
Godat, F1
Goldhirsch, A1
Brunner, KW1
Jäger, H1
Plezia, PM2
Alberts, DS2
Kessler, J1
Aapro, MS1
Graham, V1
Surwit, EA1
Ehsanullah, RS1
Galloway, DB1
Gusterson, FR1
Kingsbury, AW1
Horrobin, DF1
Trosko, JE1
Tong, FZ1
Zhang, JQ1
Qiao, XM1
Mao, YC1
Meng, FY1
Liu, HJ1
Hui, S1
Zhu, FX1
Shu, W1
Hong, J1
Luyckx, A1
Van Cauwenberge, H1
Mistakopulo, NF1
Skvabchenkov, IuN1
Rylov, VV1
Cohen, MH1
Johnston-Anderson, A1
Krasnow, SH1
Wadleigh, RG1
Kessler, JF1
Berens, PL1
Chase, JL1
Roe, DJ1
Friedman, GD1
Selby, JV1
Ballmer, PE1
Reinhart, WH1
Khonelidze, GB1
Kamyshov, IaM1
Piterskiĭ, NI1
Soltan, AF1
Gerasimova, GA1
Damascelli, B1
Terno, G1
Musumeci, R1
Preda, F1
Zaccagna, CA2
Cavalli, A2
Nadali, L1

Reviews

2 reviews available for diazepam and Benign Neoplasms

ArticleYear
[Nausea and vomiting during chemotherapy of malignant tumors].
    Schweizerische medizinische Wochenschrift, 1981, Oct-24, Volume: 111, Issue:43

    Topics: Antiemetics; Antipsychotic Agents; Diazepam; Drug-Related Side Effects and Adverse Reactions; Histam

1981
Treatment of intractable dyspnea: clinical and ethical issues.
    Cancer investigation, 1992, Volume: 10, Issue:4

    Topics: Alprazolam; Codeine; Diazepam; Dyspnea; Ethics, Medical; Humans; Infusions, Intravenous; Morphine; N

1992

Trials

6 trials available for diazepam and Benign Neoplasms

ArticleYear
Diazepam and Jacobson's progressive relaxation show similar attenuating short-term effects on stress-related brain glucose consumption.
    European psychiatry : the journal of the Association of European Psychiatrists, 2015, Volume: 30, Issue:2

    Topics: Adult; Anti-Anxiety Agents; Anxiety; Brain; Diazepam; Female; Fluorodeoxyglucose F18; Glucose; Human

2015
[Evaluation of the usefulness and effectiveness of anxiolytic therapies in neoplastic diseases].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2004, Volume: 16, Issue:96

    Topics: Adult; Aged; Alprazolam; Anti-Anxiety Agents; Antineoplastic Combined Chemotherapy Protocols; Anxiet

2004
A double-blind crossover study of diazepam rectal suppositories, 5 mg and 10 mg, for sedation in patients with advanced malignant disease.
    Pharmatherapeutica, 1982, Volume: 3, Issue:3

    Topics: Aged; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female; Humans; Male; Middle Aged; Ne

1982
[Effect of diazepam on delayed nausea and vomiting caused by anticancer agents].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:3

    Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Dexamethasone; Diazepam; Drug Administration Schedu

1998
Randomized crossover comparison of high-dose intravenous metoclopramide versus a five-drug antiemetic regimen.
    Journal of pain and symptom management, 1990, Volume: 5, Issue:2

    Topics: Adult; Aged; Cisplatin; Dexamethasone; Diazepam; Diphenhydramine; Drug Therapy, Combination; Humans;

1990
Does parenteral magnesium sulfate have an antiemetic effect during chemotherapy with cis-platinum?
    Cancer chemotherapy and pharmacology, 1989, Volume: 24, Issue:2

    Topics: Adolescent; Adult; Aged; Antiemetics; Cisplatin; Diazepam; Double-Blind Method; Drug Evaluation; Dru

1989

Other Studies

18 other studies available for diazepam and Benign Neoplasms

ArticleYear
First Bispecific Inhibitors of the Epidermal Growth Factor Receptor Kinase and the NF-κB Activity As Novel Anticancer Agents.
    Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7

    Topics: Animals; Antineoplastic Agents; Breast; Breast Neoplasms; Cell Line, Tumor; ErbB Receptors; Female;

2017
EFFICACY OF A NEW PSYCHOTROPIC DRUG IN BRONCHOSCOPY.
    Diseases of the chest, 1965, Volume: 47

    Topics: Bronchiectasis; Bronchitis; Bronchoscopy; Diazepam; Humans; Neoplasms; Pneumonia; Preanesthetic Medi

1965
Pre-medication to block [(18)F]FDG uptake in the brown adipose tissue of pediatric and adolescent patients.
    Pediatric radiology, 2005, Volume: 35, Issue:10

    Topics: Adipose Tissue, Brown; Administration, Oral; Adolescent; Adult; Age Factors; Analgesics, Opioid; Chi

2005
Nonconvulsive status epilepticus due to ifosfamide.
    The Annals of pharmacotherapy, 2006, Volume: 40, Issue:2

    Topics: Anticonvulsants; Antineoplastic Agents, Alkylating; Diazepam; Female; Humans; Ifosfamide; Levetirace

2006
Mexican drug therapy.
    Clinical toxicology, 1980, Volume: 17, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Amygdalin; Arthritis; Asthma; Diazepam; Female; Histamin

1980
Absence of effect of diazepam on tumours.
    Lancet (London, England), 1981, Jan-10, Volume: 1, Issue:8211

    Topics: Animals; Diazepam; Female; Male; Neoplasms; Rats

1981
Diazepam and tumour promotion.
    Lancet (London, England), 1981, Feb-21, Volume: 1, Issue:8217

    Topics: Animals; Cocarcinogenesis; Diazepam; Diethylnitrosamine; Female; Humans; Neoplasms; Neoplasms, Exper

1981
[Psychopharmaceuticals and cancer. Modification of tumor growth by psychoactive drugs].
    Fortschritte der Medizin, 1984, Feb-23, Volume: 102, Issue:8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Antipsychotic Agents; Breast Neoplasms; Com

1984
Immediate termination of intractable vomiting induced by cisplatin combination chemotherapy using an intensive five-drug antiemetic regimen.
    Cancer treatment reports, 1984, Volume: 68, Issue:12

    Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dexamethasone; Diazepam; Dip

1984
The possible effect of diazepam on cancer development and growth.
    Medical hypotheses, 1981, Volume: 7, Issue:1

    Topics: Animals; Breast Neoplasms; Cocarcinogenesis; Diazepam; Female; Humans; Mammary Neoplasms, Experiment

1981
[Therapeutic news of 1975].
    Revue medicale de Liege, 1976, Apr-15, Volume: 31, Issue:8

    Topics: Bismuth; Cardiovascular Diseases; Diazepam; Drug Therapy; Endocrine System Diseases; Gastrointestina

1976
IARC monographs on the evaluation of the carcinogenic risk of chemicals to man: some miscellaneous pharmaceutical substances.
    IARC monographs on the evaluation of the carcinogenic risk of chemicals to man, 1977, Volume: 13

    Topics: Acriflavine; Animals; Anthralin; Aurothioglucose; Carcinogens; Chloroquine; Diazepam; Ethanolamines;

1977
[Ataralgesia for minor oncologic surgery].
    Vestnik Akademii meditsinskikh nauk SSSR, 1979, Issue:9

    Topics: Anesthesia, General; Diazepam; Neoplasms

1979
Epidemiological screening for potentially carcinogenic drugs.
    Agents and actions. Supplements, 1990, Volume: 29

    Topics: Barbiturates; Breast Neoplasms; Carcinogens; Diazepam; Dose-Response Relationship, Drug; Erythromyci

1990
[Combination electroanesthesia in oncological patients during surgery and in the early postoperative period].
    Voprosy onkologii, 1985, Volume: 31, Issue:2

    Topics: Aged; Anesthesia, Intravenous; Diazepam; Electronarcosis; Humans; Hydroxybutyrates; Ketamine; Middle

1985
[Simple premedication with diazepam in vascular radiology].
    La Radiologia medica, 1970, Volume: 56, Issue:10

    Topics: Angiography; Aortography; Diazepam; Humans; Methods; Neoplasms; Phlebography; Technology, Radiologic

1970
[On the use of methyldiazepinone in high doses for preinduction anesthetics in oncological surgery].
    Minerva anestesiologica, 1967, Volume: 33, Issue:1

    Topics: Adult; Aged; Diazepam; Female; Humans; Male; Middle Aged; Neoplasms; Preanesthetic Medication

1967
[Clinical notes on a new synthetic psycholeptic drug in preanesthetic medication].
    Minerva anestesiologica, 1966, Volume: 32, Issue:10

    Topics: Diazepam; Humans; Neoplasms; Preanesthetic Medication

1966