Page last updated: 2024-10-25

diazepam and Benign Infantile Myoclonic Epilepsy

diazepam has been researched along with Benign Infantile Myoclonic Epilepsy in 15 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Research Excerpts

ExcerptRelevanceReference
" Following its clinical development, in September 2019 the European Medicines Agency approved its indication for the adjunctive therapy of epileptic seizures associated with Lennox-Gastaut syndrome (LGS) and Dravet syndrome (DS), combined with clobazam (CLB), in patients of 2 years of age and older."9.12Cannabidiol for the treatment of Lennox-Gastaut syndrome and Dravet syndrome: experts' recommendations for its use in clinical practice in Spain. ( García-Peñas, JJ; Gil Nagel-Rein, A; Sánchez-Carpintero, R; Villanueva-Haba, V, 2021)
" Following its clinical development, in September 2019 the European Medicines Agency approved its indication for the adjunctive therapy of epileptic seizures associated with Lennox-Gastaut syndrome (LGS) and Dravet syndrome (DS), combined with clobazam (CLB), in patients of 2 years of age and older."5.12Cannabidiol for the treatment of Lennox-Gastaut syndrome and Dravet syndrome: experts' recommendations for its use in clinical practice in Spain. ( García-Peñas, JJ; Gil Nagel-Rein, A; Sánchez-Carpintero, R; Villanueva-Haba, V, 2021)
"Dravet syndrome is a catastrophic pediatric epilepsy with severe intellectual disability, impaired social development and persistent drug-resistant seizures."1.39Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment. ( Baraban, SC; Dinday, MT; Hortopan, GA, 2013)
"Spinal cord seizures are infrequently reported."1.28Spinal cord seizures: a possible cause of isolated myoclonic activity in traumatic spinal cord injury: case report. ( Cross, LL; Meythaler, JM; Tuel, SM, 1991)
"Diazepam was injected by rectal route as an anticonvulsant, using a dose of 0."1.27Rectal diazepam: a clinical and EEG study after a single dose in children. ( Carboni, C; Franzoni, E; Lambertini, A, 1983)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19908 (53.33)18.7374
1990's2 (13.33)18.2507
2000's1 (6.67)29.6817
2010's2 (13.33)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
García-Peñas, JJ1
Gil Nagel-Rein, A1
Sánchez-Carpintero, R1
Villanueva-Haba, V1
Tiraboschi, E1
Martina, S1
van der Ent, W1
Grzyb, K1
Gawel, K1
Cordero-Maldonado, ML1
Poovathingal, SK1
Heintz, S1
Satheesh, SV1
Brattespe, J1
Xu, J1
Suster, M1
Skupin, A1
Esguerra, CV1
Warner, TA1
Smith, NK1
Kang, JQ1
Baraban, SC1
Dinday, MT1
Hortopan, GA1
WEINBERG, WA1
HARWELL, JL1
da Cunha, AF1
Carter, JE1
Grafinger, M1
Montgomery, H1
Marks, SL1
Posner, LP1
Burns, P1
Mimaki, T1
Tagawa, T1
Ono, J1
Tanaka, J1
Terada, H1
Itoh, N1
Yabuuchi, H1
Franzoni, E1
Carboni, C1
Lambertini, A1
Rothner, AD1
Erenberg, G1
Doose, H1
Gromov, SA1
Livingston, S1
Pruce, I1
Pauli, LL1
Rumpl, E1
Gerstenbrand, F1
Hengl, W1
Binder, H1
Meythaler, JM1
Tuel, SM1
Cross, LL1
Kryzhanovskiĭ, GN1
Shandra, AA1
Makul'kin, RF1
Godlevskiĭ, LS1

Reviews

1 review available for diazepam and Benign Infantile Myoclonic Epilepsy

ArticleYear
Cannabidiol for the treatment of Lennox-Gastaut syndrome and Dravet syndrome: experts' recommendations for its use in clinical practice in Spain.
    Revista de neurologia, 2021, 09-10, Volume: 73, Issue:S01

    Topics: Anticonvulsants; Cannabidiol; Clobazam; Clonazepam; Diazepam; Dioxolanes; Drug Administration Schedu

2021

Other Studies

14 other studies available for diazepam and Benign Infantile Myoclonic Epilepsy

ArticleYear
New insights into the early mechanisms of epileptogenesis in a zebrafish model of Dravet syndrome.
    Epilepsia, 2020, Volume: 61, Issue:3

    Topics: Animals; Anticonvulsants; Brain; Cell Proliferation; CRISPR-Cas Systems; Diazepam; Disease Models, A

2020
The therapeutic effect of stiripentol in Gabrg2
    Epilepsy research, 2019, Volume: 154

    Topics: Animals; Anticonvulsants; Diazepam; Dioxolanes; Epilepsies, Myoclonic; Gene Knock-In Techniques; Mic

2019
Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment.
    Nature communications, 2013, Volume: 4

    Topics: Animals; Anticonvulsants; Benzimidazoles; Bromides; Diazepam; Dioxolanes; Drug Evaluation, Preclinic

2013
DIAZEPAM (VALIUM) IN MYOCLONIC SEIZURES. FAVORABLE RESPONSE DURING INFANCY AND CHILDHOOD.
    American journal of diseases of children (1960), 1965, Volume: 109

    Topics: Anticonvulsants; Child; Diazepam; Drug Therapy; Electroencephalography; Epilepsies, Myoclonic; Epile

1965
Intrathecal morphine overdose in a dog.
    Journal of the American Veterinary Medical Association, 2007, Jun-01, Volume: 230, Issue:11

    Topics: Animals; Atracurium; Diazepam; Dog Diseases; Dogs; Drug Overdose; Epilepsies, Myoclonic; Female; Inf

2007
Antiepileptic effect and serum levels of clorazepate on children with refractory seizures.
    Brain & development, 1984, Volume: 6, Issue:6

    Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Child; Child, Preschool; Clorazepate Dipota

1984
Rectal diazepam: a clinical and EEG study after a single dose in children.
    Epilepsia, 1983, Volume: 24, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Diazepam; Electroencephalography; Epilepsies, Myoclonic; Epilep

1983
Status epilepticus.
    Pediatric clinics of North America, 1980, Volume: 27, Issue:3

    Topics: Anesthesia, General; Child; Child, Preschool; Diazepam; Epilepsies, Myoclonic; Epilepsies, Partial;

1980
Contradictory conclusions about the possible effects of prolonged febrile convulsions.
    Epilepsia, 1998, Volume: 39, Issue:1

    Topics: Brain; Diazepam; Disease Progression; Electroencephalography; Epilepsies, Myoclonic; Epilepsy, Compl

1998
[Clinical picture and basis for treating brain stem epilepsy].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1978, Volume: 78, Issue:8

    Topics: Adolescent; Adult; Anticonvulsants; Brain Stem; Diazepam; Epilepsies, Myoclonic; Epilepsy; Female; H

1978
The medical treatment of epilepsy: treatment of prolonged convulsions and status epilepticus.
    Pediatric annals, 1979, Volume: 8, Issue:4

    Topics: Adult; Anticonvulsants; Barbiturates; Child; Diazepam; Epilepsies, Myoclonic; Epilepsy, Tonic-Clonic

1979
[Electrophysiogical and neuropharmacological studies in a patient with progressive myoclonus-epilepsy (author's transl)].
    EEG-EMG Zeitschrift fur Elektroenzephalographie, Elektromyographie und verwandte Gebiete, 1977, Volume: 8, Issue:2

    Topics: Adult; Anticonvulsants; Brain; Clonazepam; Diazepam; Electroencephalography; Epilepsies, Myoclonic;

1977
Spinal cord seizures: a possible cause of isolated myoclonic activity in traumatic spinal cord injury: case report.
    Paraplegia, 1991, Volume: 29, Issue:8

    Topics: Blood Pressure; Diazepam; Electroencephalography; Epilepsies, Myoclonic; Epilepsy, Post-Traumatic; H

1991
[The hippocampus as the determinant structure generating epileptic activity during korazol kindling].
    Biulleten' eksperimental'noi biologii i meditsiny, 1985, Volume: 99, Issue:5

    Topics: Animals; Behavior, Animal; Cerebral Cortex; Diazepam; Dimethyl Sulfoxide; Electroencephalography; Ep

1985