Page last updated: 2024-10-25

diazepam and Ataxia

diazepam has been researched along with Ataxia in 64 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Ataxia: Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.

Research Excerpts

ExcerptRelevanceReference
"The motor incoordination and amnesia induced by ethyl loflazepate and CM7116 were not affected by fluvoxamine, although these adverse effects of diazepam were potentiated by fluvoxamine at 45 mg/kg."5.31[Effects of fluvoxamine on both the desired anxiolytic effect and the adverse motor incoordination and amnesia induced by benzodiazepines]. ( Baba, J; Hayashi, A; Imanishi, T; Onozawa, K, 2001)
" However, in the present study diazepam was shown to be a selective antagonist of fighting in isolated mice following chronic administration for 5 days."5.26Selective antagonism of isolation-induced aggression in mice by diazepam following chronic administration. ( Malick, JB, 1978)
"This study was designed to determine whether biofeedback is more effective than diazepam or placebo in a randomized, controlled trial for patients with pelvic floor dyssynergia-type constipation, and whether instrumented biofeedback is necessary for successful training."5.12Randomized, controlled trial shows biofeedback to be superior to alternative treatments for patients with pelvic floor dyssynergia-type constipation. ( Drossman, D; Heymen, S; Jones, K; Ringel, Y; Scarlett, Y; Whitehead, WE, 2007)
"1-10 nmol; direct GABA(A) agonist); (3) YM90K (3-10 mg/kg; AMPA receptor antagonist); and (4) diazepam (2 and 5 mg/kg) and carbamazepine (5 and 20 mg/kg), two standard anticonvulsants, using the partially-kindled hippocampal model for epileptic seizures in freely moving rats."3.70Acute effects of various GABA receptor agonists and glutamate antagonists on focal hippocampal seizures in freely moving rats elicited by low-frequency stimulation. ( Ashby, CR; Katsumori, H; Minabe, Y; Osawa, M, 1998)
"The effect of the use of a number of popular solubility treatments was examined on alfaxolone- and diazepam-induced ataxia."3.69Selective cyclodextrin inhibition of alfaxolone-induced ataxia. ( Deutsch, SI; Koetzner, L; Mastropaolo, J; Riggs, RL, 1996)
"Aromatic and heterocyclic esters of 1-methyl-4-piperidinol and 1,4-dimethyl-4-piperidinol and aromatic esters of (dialkylamino)alkanols were prepared and evaluated for antiepileptic activity by the maximal electroshock seizure (MES) and subcutaneous pentylenetetrazole seizure threshold (scMet) assays and for minimal central neurotoxicity by the rotorod ataxia test."3.67Anticonvulsant activity of piperidinol and (dialkylamino)alkanol esters. ( Creveling, CR; Daly, JW; Hollingsworth, EB; Lewandowski, G; Waters, JA, 1986)
"Separate age groups of C57BL/6 and autoimmune New Zealand Black (NZB) mice were compared for diazepam-induced ataxia and barbiturate-induced loss of righting reflex."3.67Age-dependent enhancement of diazepam sensitivity is accelerated in New Zealand Black mice. ( Forster, MJ; Lal, H; Popper, MD; Retz, KC, 1986)
"Treatment with diazepam has recently been gaining favor, particularly because of reported adverse effects of progestins."2.67Comparison of diazepam with progestin for effectiveness in suppression of urine spraying behavior in cats. ( Cooper, L; Hart, BL, 1992)
"Febrile seizures are the most common type of seizure among children that can be prevented by using prophylactic drugs like Clobazam and Diazepam."1.40Intermittent prophylaxis of recurrent febrile seizures with clobazam versus diazepam. ( Ahmed, AU; Banu, LA; Begum, SA; Haque, MA; Hoque, MR; Karim, MM; Momen, A; Parveen, F; Quddush, MR; Saha, SK; Sattar, S, 2014)
"Diazepam (2 mg/kg) induced significant ataxia and muscle relaxation, which were completely prevented by pretreatment with flumazenil (10 mg/kg) and βCCt (20 mg/kg)."1.38The role of α1 and α5 subunit-containing GABAA receptors in motor impairment induced by benzodiazepines in rats. ( Cook, JM; Divljaković, J; Milić, M; Rallapalli, S; Savić, MM; Timić, T; van Linn, ML, 2012)
" Buspirone and 8-OH-DPAT were likewise active, but yielded highly biphasic dose-response curves."1.31The selective serotonin (5-HT)1A receptor ligand, S15535, displays anxiolytic-like effects in the social interaction and Vogel models and suppresses dialysate levels of 5-HT in the dorsal hippocampus of freely-moving rats. A comparison with other anxiolyt ( Adhumeau, A; Brocco, M; Dekeyne, A; Gobert, A; Millan, MJ, 2000)
"The motor incoordination and amnesia induced by ethyl loflazepate and CM7116 were not affected by fluvoxamine, although these adverse effects of diazepam were potentiated by fluvoxamine at 45 mg/kg."1.31[Effects of fluvoxamine on both the desired anxiolytic effect and the adverse motor incoordination and amnesia induced by benzodiazepines]. ( Baba, J; Hayashi, A; Imanishi, T; Onozawa, K, 2001)
"Benzodiazepine- and alcohol-induced ataxias in rodents have been proposed to be affected by the gamma-aminobutyric acid type A (GABAA) receptor alpha 6 subunit, which contributes to receptors specifically expressed in cerebellar granule cells."1.30Cerebellar granule-cell-specific GABAA receptors attenuate benzodiazepine-induced ataxia: evidence from alpha 6-subunit-deficient mice. ( Kleinz, R; Koikkalainen, P; Korpi, ER; Mäkelä, R; Uusi-Oukari, M; Vekovischeva, OY; Wisden, W, 1999)
"Orphenadrine is an anticholinergic drug used mainly in the treatment of Parkinson's disease."1.30Orphenadrine poisoning in a child: clinical and analytical data. ( Maes, V; Mertens, K; Ramet, J; Van Herreweghe, I, 1999)
"Muscimol was a more potent stimulator of 36Cl- flux in the DS compared to the DR mice, although no difference between the lines was found in muscimol-stimulation of [3H]flunitrazepam binding."1.27Genetic selection for benzodiazepine ataxia produces functional changes in the gamma-aminobutyric acid receptor chloride channel complex. ( Allan, AM; Gallaher, EJ; Gionet, SE; Harris, RA, 1988)
" Partial protection was seen in three out of three birds dosed prior to DFP challenge with sufficient C(-)P(+) isomer of soman (1."1.27High doses of soman protect against organophosphorus-induced delayed polyneuropathy but tabun does not. ( Benschop, HP; De Bisschop, HC; Johnson, MK; Read, DJ; Willems, JL, 1988)
" However, in the present study diazepam was shown to be a selective antagonist of fighting in isolated mice following chronic administration for 5 days."1.26Selective antagonism of isolation-induced aggression in mice by diazepam following chronic administration. ( Malick, JB, 1978)

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-199040 (62.50)18.7374
1990's11 (17.19)18.2507
2000's8 (12.50)29.6817
2010's3 (4.69)24.3611
2020's2 (3.13)2.80

Authors

AuthorsStudies
Winn, M1
Arendsen, D1
Dodge, P1
Dren, A1
Dunnigan, D1
Hallas, R1
Hwang, K1
Kyncl, J1
Lee, YH1
Plotnikoff, N2
Young, P1
Zaugg, H1
Guerrini, G1
Ciciani, G1
Cambi, G1
Bruni, F1
Selleri, S1
Besnard, F1
Montali, M1
Martini, C1
Ghelardini, C1
Galeotti, N1
Costanzo, A1
Divović Matović, B1
Knutson, D1
Mitrović, J1
Stevanović, V1
Stanojević, B1
Savić, S1
Cook, JM4
Savić, MM2
Blednov, YA1
Da Costa, A1
Mason, S1
Mayfield, J1
Messing, RO1
Sattar, S1
Saha, SK1
Parveen, F1
Banu, LA1
Momen, A1
Ahmed, AU1
Quddush, MR1
Karim, MM1
Begum, SA1
Haque, MA1
Hoque, MR1
Linden, AM1
Aller, MI1
Leppä, E1
Rosenberg, PH1
Wisden, W2
Korpi, ER2
Grant, JA1
Bonnick, T1
Gossell-Williams, M1
Clayton, T1
Jackson, YA1
Milić, M1
Divljaković, J1
Rallapalli, S1
van Linn, ML1
Timić, T1
SPARK, H1
GOLDMAN, AS1
HILLYER, DM1
JACOBS, H1
Nielsen, AN1
Mathiesen, C1
Blackburn-Munro, G1
Popik, P1
Kostakis, E1
Krawczyk, M1
Nowak, G1
Szewczyk, B1
Krieter, P1
Chen, Z1
Russek, SJ1
Gibbs, TT1
Farb, DH1
Skolnick, P1
Lippa, AS1
Basile, AS1
Heymen, S1
Scarlett, Y1
Jones, K1
Ringel, Y1
Drossman, D1
Whitehead, WE1
Millan, MJ2
Gobert, A2
Panayi, F1
Rivet, JM1
Dekeyne, A2
Brocco, M2
Ortuno, JC1
Di Cara, B1
Jensen, LH1
Petersen, EN1
Braestrup, C1
Honoré, T1
Kehr, W1
Stephens, DN1
Schneider, H1
Seidelmann, D1
Schmiechen, R1
Shannon, HE2
Guzman, F1
Davis, LG1
McIntosh, H1
Reker, D1
Rosenberg, HC1
Smith, S1
Chiu, TH1
Henauer, SA1
Gallaher, EJ3
Hollister, LE1
Watanabe, M1
Yanagita, T1
Shawn, DH1
McGuigan, MA1
Griffiths, RR1
Bigelow, GE1
Liebson, I1
Dimitrijevic, MR1
Sherwood, AM1
Ikeda, H1
Igarashi, M1
Levy, JK1
O-Uchi, T1
Homick, JL1
Fischbein, CA1
Berg, IJ1
Glass, EN1
De Lahunta, A1
Jackson, C1
Hutchinson, MA1
Smith, PF1
Darlington, CL1
Koetzner, L1
Riggs, RL1
Mastropaolo, J1
Deutsch, SI1
Harrington, ML1
Moore, MP1
Talcott, PA1
Bagley, RS1
Sandmeier, P1
Katsumori, H1
Minabe, Y1
Osawa, M1
Ashby, CR1
Crabbe, JC1
Cross, SJ1
Belknap, JK1
Koikkalainen, P1
Vekovischeva, OY1
Mäkelä, R1
Kleinz, R1
Uusi-Oukari, M1
Van Herreweghe, I1
Mertens, K1
Maes, V1
Ramet, J1
Adhumeau, A1
Imanishi, T1
Onozawa, K1
Hayashi, A1
Baba, J1
Gagnon, MA1
Langlois, Y1
Boghen, DR1
Verdy, M1
Malick, JB1
Maeda, H1
Shapira, Y1
Cederbaum, SD1
Cancilla, PA1
Nielsen, D1
Lippe, BM1
Share, NN1
McFarlane, CS1
Cooper, L1
Hart, BL1
Yokota, T1
Hayashi, H1
Hirose, K1
Tanabe, H1
Allan, AM1
Gionet, SE1
Harris, RA1
Potier, MC1
Prado de Carvalho, L1
Venault, P1
Chapouthier, G1
Rossier, J1
Waters, JA1
Hollingsworth, EB1
Daly, JW1
Lewandowski, G1
Creveling, CR1
Katzman, NJ1
Johnson, MK1
Willems, JL1
De Bisschop, HC1
Read, DJ1
Benschop, HP1
Forster, MJ1
Retz, KC1
Popper, MD1
Lal, H1
Ross, JA1
Critchley, EM1
Clark, DB1
Wikler, A1
Brittain, RT1
Will, F1
Ditzler, W1
Goldstein, DB1
Klapetek, J1
Deberdt, R1
Kaemmerer, E1
Martin, DJ1
Kaelbling, R1
Wilson, LA1
Höök, O1
Landin, S1
Adamson, JE1
Cohen, BI1
Horton, CE1
Mladick, RA1
Gwyn, PP1
Bradshaw, EG1
Pleuvry, BJ1
Daly, RJ1
Kane, FJ1

Reviews

1 review available for diazepam and Ataxia

ArticleYear
Spasticity: medical and surgical treatment.
    Neurology, 1980, Volume: 30, Issue:7 Pt 2

    Topics: Ambulatory Care; Ataxia; Baclofen; Dantrolene; Diazepam; Electric Stimulation; Electrodes; Electroen

1980

Trials

3 trials available for diazepam and Ataxia

ArticleYear
Randomized, controlled trial shows biofeedback to be superior to alternative treatments for patients with pelvic floor dyssynergia-type constipation.
    Diseases of the colon and rectum, 2007, Volume: 50, Issue:4

    Topics: Ataxia; Biofeedback, Psychology; Constipation; Diazepam; Electromyography; Female; Follow-Up Studies

2007
Comparison of diazepam with progestin for effectiveness in suppression of urine spraying behavior in cats.
    Journal of the American Veterinary Medical Association, 1992, Mar-15, Volume: 200, Issue:6

    Topics: Animals; Appetite; Ataxia; Behavior, Animal; Cat Diseases; Cats; Diazepam; Female; Male; Medroxyprog

1992
[Treatment of anxiety neuroses in general practice using Lorazepam (Tavor)].
    Munchener medizinische Wochenschrift (1950), 1972, Jul-21, Volume: 114, Issue:29

    Topics: Adolescent; Adult; Anxiety Disorders; Ataxia; Diazepam; Electroencephalography; Evaluation Studies a

1972

Other Studies

60 other studies available for diazepam and Ataxia

ArticleYear
Drugs derived from cannabinoids. 5. delta6a,10a-Tetrahydrocannabinol and heterocyclic analogs containing aromatic side chains.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:4

    Topics: Aggression; Analgesics; Animals; Anticonvulsants; Antidepressive Agents; Antidiarrheals; Antihyperte

1976
Novel 3-iodo-8-ethoxypyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide as promising lead for design of alpha5-inverse agonist useful tools for therapy of mnemonic damage.
    Bioorganic & medicinal chemistry, 2007, Apr-01, Volume: 15, Issue:7

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Ataxia; Diazepam; Drug Design; GABA Agonists; gamma-Aminobuty

2007
Behavioural interaction of pyrazoloquinolinone positive allosteric modulators at α6GABA
    Basic & clinical pharmacology & toxicology, 2022, Volume: 131, Issue:6

    Topics: Animals; Ataxia; Benzodiazepines; Diazepam; GABA Modulators; gamma-Aminobutyric Acid; Ligands; Male;

2022
Selective PDE4B and PDE4D inhibitors produce distinct behavioral responses to ethanol and GABAergic drugs in mice.
    Neuropharmacology, 2023, 06-15, Volume: 231

    Topics: Animals; Ataxia; Cyclic Nucleotide Phosphodiesterases, Type 4; Diazepam; Ethanol; Female; Hypnotics

2023
Intermittent prophylaxis of recurrent febrile seizures with clobazam versus diazepam.
    Mymensingh medical journal : MMJ, 2014, Volume: 23, Issue:4

    Topics: Age Factors; Anticonvulsants; Ataxia; Bangladesh; Benzodiazepines; Chi-Square Distribution; Child, P

2014
K+ channel TASK-1 knockout mice show enhanced sensitivities to ataxic and hypnotic effects of GABA(A) receptor ligands.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 327, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Ataxia; Benzodiazepines; Brain; Diazepam; Female; Flurazepam; Hypnotic

2008
Synthesis, pharmacological studies and molecular modeling of some tetracyclic 1,3-diazepinium chlorides.
    Bioorganic & medicinal chemistry, 2010, Jan-15, Volume: 18, Issue:2

    Topics: Animals; Ataxia; Azepines; Central Nervous System; Diazepam; Female; Male; Mice; Models, Animal; Mod

2010
The role of α1 and α5 subunit-containing GABAA receptors in motor impairment induced by benzodiazepines in rats.
    Behavioural pharmacology, 2012, Volume: 23, Issue:2

    Topics: Animals; Ataxia; Benzodiazepines; Benzodiazepinones; Carbolines; Diazepam; Flumazenil; GABA-A Recept

2012
DIAZEPAM INTOXICATION IN A CHILD.
    American journal of diseases of children (1960), 1965, Volume: 109

    Topics: Ataxia; Child; Chlordiazepoxide; Diazepam; Electroencephalography; Metabolism; Poisoning; Sleep Wake

1965
AN OVERDOSE OF "VALIUM".
    The Medical journal of Australia, 1965, Volume: 1

    Topics: Ataxia; Diazepam; Drug Overdose; Drug Tolerance; Pharmacology; Toxicology

1965
MYOCLONUS AND ATAXIA OCCURING IN A FAMILY.
    Journal of neurology, neurosurgery, and psychiatry, 1965, Volume: 28

    Topics: Adolescent; Ataxia; Child; Diazepam; Drug Therapy; Genetics, Medical; Humans; Myoclonic Cerebellar D

1965
Pharmacological characterisation of acid-induced muscle allodynia in rats.
    European journal of pharmacology, 2004, Mar-08, Volume: 487, Issue:1-3

    Topics: Acids; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ataxia; Carbazoles; Chr

2004
The anxioselective agent 7-(2-chloropyridin-4-yl)pyrazolo-[1,5-a]-pyrimidin-3-yl](pyridin-2-yl)methanone (DOV 51892) is more efficacious than diazepam at enhancing GABA-gated currents at alpha1 subunit-containing GABAA receptors.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 319, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Ataxia; Chloride Channels; Diazepam; Dose-Response Relationship, Drug;

2006
The melanin-concentrating hormone1 receptor antagonists, SNAP-7941 and GW3430, enhance social recognition and dialysate levels of acetylcholine in the frontal cortex of rats.
    The international journal of neuropsychopharmacology, 2008, Volume: 11, Issue:8

    Topics: Acetylcholine; Aggression; Animals; Anxiety; Ataxia; Brain Chemistry; Conflict, Psychological; Data

2008
Evaluation of the beta-carboline ZK 93 426 as a benzodiazepine receptor antagonist.
    Psychopharmacology, 1984, Volume: 83, Issue:3

    Topics: Animals; Anticonvulsants; Ataxia; Benzodiazepinones; Binding, Competitive; Carbolines; Diazepam; Dis

1984
beta-Carboline-3-carboxylate-t-butyl ester: a selective BZ1 benzodiazepine receptor antagonist.
    Life sciences, 1984, Nov-26, Volume: 35, Issue:22

    Topics: Animals; Anticonvulsants; Ataxia; Benzodiazepines; Binding, Competitive; Carbolines; Conditioning, O

1984
An endogenous ligand to the benzodiazepine receptor: preliminary evaluation of its bioactivity.
    Pharmacology, biochemistry, and behavior, 1981, Volume: 14, Issue:6

    Topics: Animals; Anticonvulsants; Ataxia; Behavior, Animal; Body Temperature; Cattle; Conflict, Psychologica

1981
Benzodiazepine--specific and nonspecific tolerance following chronic flurazepam treatment.
    Life sciences, 1983, Jan-17, Volume: 32, Issue:3

    Topics: Animals; Ataxia; Diazepam; Drug Tolerance; Ethanol; Flurazepam; Male; Rats; Receptors, Cell Surface;

1983
Long-lasting single-dose tolerance to neurologic deficits induced by diazepam.
    Psychopharmacology, 1984, Volume: 82, Issue:3

    Topics: Administration, Oral; Animals; Ataxia; Diazepam; Drug Tolerance; Male; Nervous System Diseases; Rats

1984
Toxicological studies on the influence of diazepam following prolonged administration of ethanol in the rhesus monkey and rat.
    The Journal of toxicological sciences, 1983, Volume: 8, Issue:4

    Topics: Alanine Transaminase; Animals; Ataxia; Diazepam; Ethanol; Female; Liver; Macaca mulatta; Male; Organ

1983
Poisoning from dermal absorption of promethazine.
    Canadian Medical Association journal, 1984, Jun-01, Volume: 130, Issue:11

    Topics: Administration, Topical; Akathisia, Drug-Induced; Ataxia; Child, Preschool; Diazepam; Eczema; Female

1984
Human preference comparison of pentobarbital, diazepam, and placebo.
    NIDA research monograph, 1981, Volume: 34

    Topics: Ataxia; Diazepam; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hypnotics and Sedat

1981
[Pharmacological studies on the functional development of the central nervous system in first generation rats born to phenytoin-treated mothers (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1982, Volume: 79, Issue:1

    Topics: Animals; Animals, Newborn; Ataxia; Birth Rate; Brain; Catalepsy; Diazepam; Eye; Feeding Behavior; Fe

1982
Diazepam-induced ataxia in trotting squirrel monkeys.
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1980, Volume: 21, Issue:3

    Topics: Animals; Ataxia; Diazepam; Female; Male; Saimiri

1980
Diazepam to prevent febrile seizures.
    The New England journal of medicine, 1993, Dec-30, Volume: 329, Issue:27

    Topics: Ataxia; Child; Diazepam; Humans; Seizures, Febrile

1993
Brain abscess in a goat.
    The Cornell veterinarian, 1993, Volume: 83, Issue:4

    Topics: Animals; Ataxia; Brain; Brain Abscess; Cerebellar Diseases; Corynebacterium Infections; Corynebacter

1993
Tolerance to the ataxic effects of diazepam in guinea pig is not associated with a reduced sensitivity of GABAA receptors in the vestibular nucleus.
    European journal of pharmacology, 1996, Apr-22, Volume: 301, Issue:1-3

    Topics: Animals; Ataxia; Behavior, Animal; Brain Stem; Diazepam; Drug Tolerance; Electrophysiology; GABA Ago

1996
Selective cyclodextrin inhibition of alfaxolone-induced ataxia.
    The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:5

    Topics: Animals; Ataxia; Cyclodextrins; Diazepam; Dose-Response Relationship, Drug; Ethanol; Male; Mice; Pha

1996
Suspected herbicide toxicosis in a dog.
    Journal of the American Veterinary Medical Association, 1996, Dec-15, Volume: 209, Issue:12

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Abdominal Pain; Animals; Anorexia; Antidotes; Antiemetics; Atax

1996
Acute effects of various GABA receptor agonists and glutamate antagonists on focal hippocampal seizures in freely moving rats elicited by low-frequency stimulation.
    Synapse (New York, N.Y.), 1998, Volume: 28, Issue:1

    Topics: Animals; Anticonvulsants; Ataxia; Carbamazepine; Diazepam; Dizocilpine Maleate; Excitatory Amino Aci

1998
Genetic determinants of sensitivity to diazepam in inbred mice.
    Behavioral neuroscience, 1998, Volume: 112, Issue:3

    Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Ataxia; Brain; Diazepam; Disease Susceptibility;

1998
Cerebellar granule-cell-specific GABAA receptors attenuate benzodiazepine-induced ataxia: evidence from alpha 6-subunit-deficient mice.
    The European journal of neuroscience, 1999, Volume: 11, Issue:1

    Topics: Animals; Ataxia; Benzodiazepines; Central Nervous System Depressants; Diazepam; Ethanol; GABA Modula

1999
Orphenadrine poisoning in a child: clinical and analytical data.
    Intensive care medicine, 1999, Volume: 25, Issue:10

    Topics: Akathisia, Drug-Induced; Anti-Arrhythmia Agents; Anticonvulsants; Antiparkinson Agents; Ataxia; Chil

1999
The selective serotonin (5-HT)1A receptor ligand, S15535, displays anxiolytic-like effects in the social interaction and Vogel models and suppresses dialysate levels of 5-HT in the dorsal hippocampus of freely-moving rats. A comparison with other anxiolyt
    Psychopharmacology, 2000, Volume: 152, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Ataxia; Conflict, Psychologica

2000
[Effects of fluvoxamine on both the desired anxiolytic effect and the adverse motor incoordination and amnesia induced by benzodiazepines].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2001, Volume: 118, Issue:6

    Topics: Amnesia; Animals; Anti-Anxiety Agents; Ataxia; Benzodiazepines; Diazepam; Dose-Response Relationship

2001
Effects of halazepam and diazepam on the motor coordination of geriatric subjects.
    European journal of clinical pharmacology, 1977, Jul-19, Volume: 11, Issue:6

    Topics: Aged; Anti-Anxiety Agents; Ataxia; Benzodiazepines; Diazepam; Double-Blind Method; Female; Gait; Hum

1977
Selective antagonism of isolation-induced aggression in mice by diazepam following chronic administration.
    Pharmacology, biochemistry, and behavior, 1978, Volume: 8, Issue:4

    Topics: Aggression; Animals; Ataxia; Diazepam; Humans; Male; Mice; Social Isolation

1978
Effects of psychotropic drugs upon the hypothalamic rage response in cats.
    Folia psychiatrica et neurologica japonica, 1976, Volume: 30, Issue:4

    Topics: Anger; Animals; Ataxia; Cats; Chlorpromazine; Diazepam; Haloperidol; Hypothalamus; Hypothalamus, Mid

1976
Familial poliodystrophy, mitochondrial myopathy, and lactate acidemia.
    Neurology, 1975, Volume: 25, Issue:7

    Topics: Adolescent; Ataxia; Cerebral Cortex; Child; Child, Preschool; Diazepam; Diffuse Cerebral Sclerosis o

1975
Cyclobenzaprine: novel centrally acting skeletal muscle relaxant.
    Neuropharmacology, 1975, Volume: 14, Issue:9

    Topics: Amitriptyline; Animals; Anticonvulsants; Ataxia; Cats; Chlorpromazine; Decerebrate State; Diazepam;

1975
Unusual blink reflex with four components in a patient with periodic ataxia.
    Journal of neurology, 1990, Volume: 237, Issue:5

    Topics: Ataxia; Blinking; Diazepam; Female; Humans; Middle Aged; Periodicity

1990
Genetic selection for benzodiazepine ataxia produces functional changes in the gamma-aminobutyric acid receptor chloride channel complex.
    Brain research, 1988, Jun-14, Volume: 452, Issue:1-2

    Topics: Animals; Ataxia; Chlorides; Diazepam; Ethanol; Flunitrazepam; Ion Channels; Isoxazoles; Mice; Muscim

1988
Demonstration of the partial agonist profiles of Ro 16-6028 and Ro 17-1812 in mice in vivo.
    European journal of pharmacology, 1988, Oct-26, Volume: 156, Issue:1

    Topics: Animals; Anticonvulsants; Ataxia; Benzodiazepinones; Brain; Conflict, Psychological; Diazepam; Male;

1988
Anticonvulsant activity of piperidinol and (dialkylamino)alkanol esters.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:8

    Topics: Amino Alcohols; Animals; Anticonvulsants; Ataxia; Bridged Bicyclo Compounds; Bridged Bicyclo Compoun

1986
CGS 8216: agonist and diazepam-antagonist effects in rodents.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:1

    Topics: Animals; Ataxia; Behavior, Animal; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Fl

1986
High doses of soman protect against organophosphorus-induced delayed polyneuropathy but tabun does not.
    Toxicology and applied pharmacology, 1988, Volume: 92, Issue:1

    Topics: Animals; Ataxia; Atropine; Carboxylic Ester Hydrolases; Chickens; Diazepam; Drug Interactions; Femal

1988
Age-dependent enhancement of diazepam sensitivity is accelerated in New Zealand Black mice.
    Life sciences, 1986, Apr-14, Volume: 38, Issue:15

    Topics: Aging; Animals; Ataxia; Barbiturates; Body Weight; Diazepam; Dose-Response Relationship, Drug; Male;

1986
Tremor and ataxia in a West Highland white terrier.
    The Veterinary record, 1985, Jul-20, Volume: 117, Issue:3

    Topics: Animals; Ataxia; Diazepam; Dog Diseases; Dogs; Drug Therapy, Combination; Female; Furosemide; Nystag

1985
An adult form of acanthocytosis.
    Transactions of the American Neurological Association, 1967, Volume: 92

    Topics: Abetalipoproteinemia; Adult; Ataxia; Diazepam; Female; Haloperidol; Humans; Huntington Disease; Hydr

1967
The intracerebral effects of noradrenaline and its modification by drugs in the mouse.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:9

    Topics: Amitriptyline; Animals; Antidepressive Agents; Ataxia; Atropine; Body Temperature; Brain; Central Ne

1966
Stimulant activity of pemoline and magnesium hydroxide.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 181, Issue:2

    Topics: Animals; Antacids; Ataxia; Caffeine; Cats; Central Nervous System Stimulants; Chlordiazepoxide; Chlo

1969
An animal model for testing effects of drugs on alcohol withdrawal reactions.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 183, Issue:1

    Topics: Animals; Ataxia; Barbiturates; Chlordiazepoxide; Chlormethiazole; Diazepam; Ethanol; Humans; Male; M

1972
[Valoron intoxication in attempted suicide].
    Munchener medizinische Wochenschrift (1950), 1973, Jan-26, Volume: 115, Issue:4

    Topics: Adult; Amines; Ataxia; Color; Cyclohexanecarboxylic Acids; Diazepam; Glucose; Humans; Hyperventilati

1973
Lorazepam in the treatment of severe anxiety and anxiety associated with psychotic conditions.
    Current medical research and opinion, 1973, Volume: 1, Issue:5

    Topics: Adult; Aggression; Amitriptyline; Anxiety Disorders; Ataxia; Benzodiazepinones; Bipolar Disorder; Ch

1973
Diazepam-modified electroconvulsive therapy.
    Biological psychiatry, 1971, Volume: 3, Issue:2

    Topics: Adult; Aged; Anesthesia, General; Arrhythmias, Cardiac; Ataxia; Atropine; Blood Pressure; Diazepam;

1971
The management of spasticity and rigidity using parenteral diazepam.
    Gerontologia clinica, 1970, Volume: 12, Issue:3

    Topics: Adult; Aged; Ataxia; Central Nervous System Diseases; Diazepam; Fatigue; Female; Humans; Injections,

1970
[Multiple sclerosis. 7. Rehabilitation].
    Lakartidningen, 1970, Jul-15, Volume: 67, Issue:29

    Topics: Ataxia; Diazepam; Exercise Therapy; Humans; Multiple Sclerosis; Self-Help Devices; Spasm; Urination

1970
Intravenous diazepam: a helpful adjunct in plastic surgery.
    Plastic and reconstructive surgery, 1971, Volume: 47, Issue:2

    Topics: Adolescent; Adult; Aged; Amnesia; Anesthesia, Local; Arrhythmias, Cardiac; Ataxia; Child; Diazepam;

1971
Respiratory and hypnotic effects of nitrazepam, diazepam and pentobarbitone and their solvents in the rabbit and the mouse.
    British journal of anaesthesia, 1971, Volume: 43, Issue:7

    Topics: Animals; Ataxia; Benzazepines; Diazepam; Female; Hypnotics and Sedatives; Injections, Intraperitonea

1971
Two severe reactions to benzodiazepine compounds.
    The American journal of psychiatry, 1965, Volume: 122, Issue:5

    Topics: Adult; Alcoholism; Ataxia; Chlordiazepoxide; Diazepam; Drug Synergism; Humans; Male; Middle Aged; Mu

1965