diazepam and Asystole studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Research Excerpts

Excerpt	Relevance	Reference
"A retrospective study was carried out, over a twelve-year period, of all cases of acute chloroquine poisoning where more than 2 g of chloroquine had been taken."	10.17	[Effects of diazepam on mortality from acute chloroquine poisoning]. ( Demaziere, J; Gaye, M; Marcoux, L; Ndiaye, M; Saissy, JM; Seck, M; Vitris, M, 1992)
"Ten patients developed apnea or cardiopulmonary arrest during or following endoscopy in more than 10,000 consecutive endoscopies."	7.68	Apnea and cardiopulmonary arrest during and after endoscopy. ( Iber, FL; Kruss, DM; Livak, A, 1992)
"A retrospective study was carried out, over a twelve-year period, of all cases of acute chloroquine poisoning where more than 2 g of chloroquine had been taken."	6.17	[Effects of diazepam on mortality from acute chloroquine poisoning]. ( Demaziere, J; Gaye, M; Marcoux, L; Ndiaye, M; Saissy, JM; Seck, M; Vitris, M, 1992)
"Ten patients developed apnea or cardiopulmonary arrest during or following endoscopy in more than 10,000 consecutive endoscopies."	3.68	Apnea and cardiopulmonary arrest during and after endoscopy. ( Iber, FL; Kruss, DM; Livak, A, 1992)
"Post-anoxic myoclonus is a rare movement disorder manifested by diffuse action-triggered jerking movements that may result in significant disability."	1.33	Post-anoxic myoclonus: a case presentation and review of management in the rehabilitation setting. ( Polesin, A; Stern, M, 2006)
"A 75-year-old man suffered a cardiac arrest and severe anoxic encephalopathy."	1.30	Periodic complexes, absence-like status and suppression-burst pattern in coma following cardiorespiratory arrest. ( Chemmale, J; Devrajan, VN; Ganji, SS; McDonald, L; Palliyath, S, 1997)
"Four minutes later, cardiac arrest occurred."	1.29	[Hypoxic brain damage after prolonged cardiac arrest during anesthesia--changes in CT and serum NSE concentration]. ( Imaizumi, H; Kaneko, M; Namiki, A; Tsuruoka, K; Ujike, Y, 1994)
" A dosage of 30 to 40 mg of ketamine HCl/kg of body weight and 1."	1.26	Intravenously administered ketamine HCl and diazepam for anesthesia of raptors. ( Duke, GE; Redig, PT, 1976)

Timeframe	Studies, this research(%)	All Research%
pre-1990	24 (58.54)	18.7374
1990's	10 (24.39)	18.2507
2000's	6 (14.63)	29.6817
2010's	1 (2.44)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
Shimozono, K	1
Taba, M	1
Hanaki, S	1
Longstreth, WT	1
Fahrenbruch, CE	1
Olsufka, M	1
Walsh, TR	1
Copass, MK	1
Cobb, LA	1
Landau, WM	1
Machado, C	1
Compton, R	1
Spiller, HA	1
Bosse, GM	1
Polesin, A	1
Stern, M	1
Takinami, Y	1
Greenberg, MI	1
Powers, RD	1
Donowitz, LG	1
Donaldson, D	1
Gibson, G	1
Kornfeld, DS	1
Edelen, WB	1
Chapman, PJ	1
Myles, PS	1
Hall, JL	1
Berry, CB	1
Esmore, DS	1
Imaizumi, H	1
Tsuruoka, K	1
Ujike, Y	1
Kaneko, M	1
Namiki, A	1
Clemessy, JL	1
Taboulet, P	1
Hoffman, JR	1
Hantson, P	1
Barriot, P	1
Bismuth, C	1
Baud, FJ	1
Ganji, SS	1
Palliyath, S	1
Chemmale, J	1
Devrajan, VN	1
McDonald, L	1
Camacho, JA	1
Jiménez, JM	1
Díaz, A	1
Montijano, A	1
Quesada, JL	1
Montiel, D	1
Wilkinson, HA	1
Geevarghese, KP	1
Shields, CB	1
Gray, LA	1
Redig, PT	1
Duke, GE	1
Sherman, PM	2
Darke, SG	1
Bloomfield, E	1
Berger, R	1
Green, G	1
Melnick, A	1
Quenstedt, M	1
Ramsay, R	1
Bernadt, M	1
Demaziere, J	1
Saissy, JM	1
Vitris, M	1
Seck, M	1
Ndiaye, M	1
Gaye, M	1
Marcoux, L	1
Iber, FL	1
Livak, A	1
Kruss, DM	1
D'Eramo, EM	1
Berk, WA	1
Andersen, JC	1
Maryniak, JK	1
Bishop, VA	1
Stone, B	1
Barkin, JS	1
Panullo, W	1
Rogers, AI	1
Baniel, J	1
Ram, Z	1
Shemer, J	1
Lazar, M	1
Grivaux, M	1
Soulié, J	1
Diallo, A	1
Renard, C	1
Chevalley, J	1
De Jong, RH	1
Heavner, JE	1
McClish, A	1
Bénazéra, A	1
Lapointe, P	1
Cohen, CA	1
Smith, TC	1

Trial			Phase	Enrollment	Study Type	Start Date	Status
Comparison of Intubation Conditions After Induction With Propofol Associated With a Dose of Remifentanil or Sufentanil in Surgical Tooth Extraction.[NCT01910285]			Phase 4	70 participants (Actual)	Interventional	2013-06-30	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
The intensive care unit in adults: coronary care and general medical/surgical. Advances in psychosomatic medicine, 1980, Volume: 10 Topics: Adult; Anxiety; Arrhythmias, Cardiac; Catholicism; Chaplaincy Service, Hospital; Coronary Care Units	1980
[Severe-grade tetanus in a multipurpose ICU: review of 13 cases]. Enfermedades infecciosas y microbiologia clinica, 1997, Volume: 15, Issue:5 Topics: Acinetobacter Infections; Adult; Aged; Cause of Death; Combined Modality Therapy; Debridement; Diaze	1997
[Effects of diazepam on mortality from acute chloroquine poisoning]. Annales francaises d'anesthesie et de reanimation, 1992, Volume: 11, Issue:2 Topics: Acute Disease; Adolescent; Adult; Chloroquine; Diazepam; Female; Heart Arrest; Humans; Male; Poisoni	1992

Article	Year
Randomized clinical trial of magnesium, diazepam, or both after out-of-hospital cardiac arrest. Neurology, 2002, Aug-27, Volume: 59, Issue:4 Topics: Activities of Daily Living; Aged; Allied Health Personnel; Confounding Factors, Epidemiologic; Diaze	2002
Randomized clinical trial of magnesium, diazepam, or both after out-of-hospital cardiac arrest. Neurology, 2003, Jun-10, Volume: 60, Issue:11 Topics: Brain Diseases; Diazepam; Drug Therapy, Combination; Heart Arrest; Humans; Magnesium; Neuropsycholog	2003
[Effects of diazepam on mortality from acute chloroquine poisoning]. Annales francaises d'anesthesie et de reanimation, 1992, Volume: 11, Issue:2 Topics: Acute Disease; Adolescent; Adult; Chloroquine; Diazepam; Female; Heart Arrest; Humans; Male; Poisoni	1992

diazepam and Asystole

Research Excerpts

Research

Studies (41)

Authors

Clinical Trials (1)

Trial Overview

Reviews

Trials

Other Studies

Article	Year
[A case of post-cardiac arrest syndrome presenting with lateralized periodic discharges evolving to a cyclic seizure pattern on electroencephalogram]. Rinsho shinkeigaku = Clinical neurology, 2019, Jul-31, Volume: 59, Issue:7 Topics: Anticonvulsants; Arrhythmias, Cardiac; Coronary Vasospasm; Diazepam; Electroencephalography; Heart A	2019
Randomized clinical trial of magnesium, diazepam, or both after out-of-hospital cardiac arrest. Neurology, 2003, Jun-10, Volume: 60, Issue:11 Topics: Animals; Brain Ischemia; Diazepam; Dogs; Drug Therapy, Combination; Heart Arrest; Humans; Hypothermi	2003
Fatal fluoxetine ingestion with postmortem blood concentrations. Clinical toxicology (Philadelphia, Pa.), 2005, Volume: 43, Issue:4 Topics: Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Bradycardia; Child, Preschool; Dia	2005
Post-anoxic myoclonus: a case presentation and review of management in the rehabilitation setting. Brain injury, 2006, Volume: 20, Issue:2 Topics: Anticonvulsants; Clonazepam; Diazepam; Female; Heart Arrest; Humans; Hypoxia, Brain; Isoxazoles; Lev	2006
[Case of serious lidocaine intoxication]. Masui. The Japanese journal of anesthesiology, 2008, Volume: 57, Issue:4 Topics: Anesthetics, Local; Atropine; Brachial Plexus; Cardiac Pacing, Artificial; Diazepam; Heart Arrest; H	2008
The use of endotracheal medication in cardiac emergencies. Resuscitation, 1984, Volume: 12, Issue:3 Topics: Atropine; Bradycardia; Diazepam; Electrocardiography; Emergencies; Epinephrine; Heart Arrest; Humans	1984
Endotracheal administration of emergency medications. Southern medical journal, 1984, Volume: 77, Issue:3 Topics: Adult; Anaphylaxis; Anti-Arrhythmia Agents; Atropine; Bicarbonates; Diazepam; Emergencies; Epinephri	1984
Systemic complications with intravenous diazepam. Oral surgery, oral medicine, and oral pathology, 1980, Volume: 49, Issue:2 Topics: Adult; Aged; Child, Preschool; Coma; Diazepam; Drug Hypersensitivity; Heart Arrest; Humans; Hysteria	1980
Dangers of intravenously administered diazepam. American journal of ophthalmology, 1981, Volume: 91, Issue:2 Topics: Aged; Diazepam; Female; Heart Arrest; Humans; Injections, Intravenous; Ophthalmologic Surgical Proce	1981
A questionnaire survey of dentists regarding knowledge and perceived competence in resuscitation and occurrence of resuscitation emergencies. Australian dental journal, 1995, Volume: 40, Issue:2 Topics: Adult; Attitude of Health Personnel; Australia; Cardiopulmonary Resuscitation; Clinical Competence;	1995
Primary pulmonary hypertension: prolonged cardiac arrest and successful resuscitation following induction of anesthesia for heart-lung transplantation. Journal of cardiothoracic and vascular anesthesia, 1994, Volume: 8, Issue:6 Topics: Adult; Anesthesia, Intravenous; Cardiopulmonary Bypass; Cardiopulmonary Resuscitation; Diazepam; Fen	1994
[Hypoxic brain damage after prolonged cardiac arrest during anesthesia--changes in CT and serum NSE concentration]. Masui. The Japanese journal of anesthesiology, 1994, Volume: 43, Issue:8 Topics: Anesthesia, Spinal; Brain Death; Diazepam; Female; Heart Arrest; Humans; Hypoxia; Hysterectomy; Midd	1994
Treatment of acute chloroquine poisoning: a 5-year experience. Critical care medicine, 1996, Volume: 24, Issue:7 Topics: Acute Disease; Adult; Chloroquine; Combined Modality Therapy; Diazepam; Drug Overdose; Drug Therapy,	1996
Periodic complexes, absence-like status and suppression-burst pattern in coma following cardiorespiratory arrest. Clinical EEG (electroencephalography), 1997, Volume: 28, Issue:2 Topics: Aged; Anticonvulsants; Brain; Coma; Diazepam; Electroencephalography; Epilepsy, Absence; Heart Arres	1997
Re: "Troubles in medical academe": a clarification. JAMA, 1977, Jan-03, Volume: 237, Issue:1 Topics: Amobarbital; Diazepam; Epilepsy; Heart Arrest; Humans	1977
Anesthetic management for direct approach to carotid-cavernous fistula: case report. International anesthesiology clinics, 1977,Fall, Volume: 15, Issue:3 Topics: Adult; Anesthesia; Arteriovenous Fistula; Atropine; Carotid Artery Diseases; Cavernous Sinus; Dexame	1977
Intravenously administered ketamine HCl and diazepam for anesthesia of raptors. Journal of the American Veterinary Medical Association, 1976, Nov-01, Volume: 169, Issue:9 Topics: Anesthesia, General; Animals; Bird Diseases; Birds; Diazepam; Heart Arrest; Injections, Intravenous;	1976
Letter: Further comments on cardiac arrest from diazepam. Journal of oral surgery (American Dental Association : 1965), 1975, Volume: 33, Issue:2 Topics: Anesthesia, Local; Diazepam; Heart Arrest; Humans	1975
Case of complete gastric rupture complicating resuscitation. British medical journal, 1975, Aug-16, Volume: 3, Issue:5980 Topics: Adult; Anesthesia, Dental; Anesthesia, Intravenous; Diazepam; Female; Heart Arrest; Heart Massage; H	1975
Cardiac arrest caused by oral diazepam intoxication. Clinical pediatrics, 1975, Volume: 14, Issue:9 Topics: Child, Preschool; Diazepam; Electrocardiography; Female; Heart Arrest; Heart Massage; Humans; Remiss	1975
Rapid tranquillisation. The British journal of psychiatry : the journal of mental science, 1992, Volume: 161 Topics: Adult; Arousal; Chlorpromazine; Coma; Diazepam; Dose-Response Relationship, Drug; Drug Therapy, Comb	1992
Apnea and cardiopulmonary arrest during and after endoscopy. Journal of clinical gastroenterology, 1992, Volume: 14, Issue:2 Topics: Aged; Apnea; Butorphanol; Databases, Factual; Diazepam; Endoscopy, Gastrointestinal; Heart Arrest; H	1992
Morbidity and mortality with outpatient anesthesia: the Massachusetts experience. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1992, Volume: 50, Issue:7 Topics: Aged; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthesia, General; Anesthesia, Intraveno	1992
Salicylate-associated asystole: report of two cases. The American journal of medicine, 1989, Volume: 86, Issue:4 Topics: Aged; Arrhythmias, Cardiac; Diazepam; Female; Heart Arrest; Humans; Male; Middle Aged; Respiratory I	1989
Sinus arrest after alfentanil. British journal of anaesthesia, 1987, Volume: 59, Issue:3 Topics: Alfentanil; Anesthesia, Intravenous; Anesthetics; Diazepam; Fentanyl; Heart Arrest; Humans; Intubati	1987
Hypercalcemia: a risk factor to patients undergoing gastrointestinal endoscopy. The American journal of gastroenterology, 1986, Volume: 81, Issue:7 Topics: Aged; Apnea; Carcinoma, Squamous Cell; Diazepam; Drug Synergism; Esophageal Neoplasms; Esophagoscopy	1986
[Endotracheal drug administration]. Harefuah, 1985, May-15, Volume: 108, Issue:10 Topics: Aerosols; Animals; Atropine; Cardiovascular Agents; Diazepam; Epinephrine; Heart Arrest; Humans; Lid	1985
[Pathogenesis and therapy of tetanus]. Schweizerische medizinische Wochenschrift, 1970, Aug-29, Volume: 100, Issue:35 Topics: Diazepam; Heart Arrest; Humans; Hypertension; Muscle Cramp; Neuromuscular Nondepolarizing Agents; Pr	1970
Another death during dentistry. British medical journal, 1974, Nov-09, Volume: 4, Issue:5940 Topics: Adult; Anesthesia, Dental; Diazepam; Drug Synergism; Female; Heart Arrest; Humans; Hypoxia; Jurispru	1974
ASOS anesthesia morbidity and mortality survey. Journal of oral surgery (American Dental Association : 1965), 1974, Volume: 32, Issue:10 Topics: Administration, Oral; Anesthesia, Dental; Anesthesia, General; Anesthesia, Local; Anesthesiology; Ce	1974
Letter: Cardiac arrest with diazepam. Journal of oral surgery (American Dental Association : 1965), 1974, Volume: 32, Issue:11 Topics: Alcoholism; Diazepam; Heart Arrest; Humans; Respiratory Insufficiency	1974
Letter: Cardiac arrest with diazepam. Journal of oral surgery (American Dental Association : 1965), 1974, Volume: 32, Issue:8 Topics: Adult; Atropine; Diazepam; Female; Fracture Fixation; Heart Arrest; Heart Massage; Humans; Injection	1974
[Therapeutic hyperosmolarity]. Annales de medecine interne, 1973, Volume: 124, Issue:3 Topics: Adult; Bicarbonates; Blood Transfusion; Brain Diseases; Chemical and Drug Induced Liver Injury; Diaz	1973
Convulsions induced by local anaesthetic: time course of diazepam prophylaxis. Canadian Anaesthetists' Society journal, 1974, Volume: 21, Issue:2 Topics: Anesthesia, Intravenous; Anesthesia, Local; Animals; Cats; Diazepam; Dose-Response Relationship, Dru	1974
[Light halothane anesthesia for pacemaker implantation (series of 200 cases)]. L'union medicale du Canada, 1974, Volume: 103, Issue:5 Topics: Adolescent; Adult; Aged; Anesthesia, General; Arrhythmias, Cardiac; Child; Diabetes Complications; D	1974
The intraoperative hazard of acrylic bone cement: report of a case. Anesthesiology, 1971, Volume: 35, Issue:5 Topics: Acrylic Resins; Atropine; Autopsy; Bone Cements; Diazepam; Electrocardiography; Female; Femur; Fenta	1971