diazepam has been researched along with Arthritis, Rheumatoid in 12 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seventeen of eighteen patients hospitalized for active rheumatoid arthritis completed a three-day randomized, double-blind comparison of 100 mg indomethacin, 100 mg indomethacin with 10 mg diazepam and matching placebo as night medication." | 9.04 | Night medication in rheumatoid arthritis: II. Combined therapy with indomethacin and diazepam. ( Haslock, I; Hobkirk, D; Rhodes, M, 1977) |
| "A double-blind controlled trial was carried out in 18 in-patients with classical or definite rheumatoid arthritis to assess the effectiveness of night-time medication with 100 mg indomethacin plus 10 mg diazepam, 200 mg sulindac, and 200 mg sulindac plus 10 mg diazepam in improving sleep and reducing night pain and the duration of morning stiffness." | 5.04 | Night medication in rheumatoid arthritis. III. the use of sulindac. ( Haslock, I; Sharma, BK, 1978) |
| "The efficacy of indomethacin 100 mg, diazepam 10 mg, and placebo in producing sleep, relieving night pain, and reducing the severity of morning stiffness, was compared in 18 patients in hospital with active classical or definite rheumatoid arthritis." | 5.04 | Night medication in rheumatoid arthritis. ( Bayley, TR; Haslock, I, 1976) |
| "Seventeen of eighteen patients hospitalized for active rheumatoid arthritis completed a three-day randomized, double-blind comparison of 100 mg indomethacin, 100 mg indomethacin with 10 mg diazepam and matching placebo as night medication." | 5.04 | Night medication in rheumatoid arthritis: II. Combined therapy with indomethacin and diazepam. ( Haslock, I; Hobkirk, D; Rhodes, M, 1977) |
| "Based upon the currently available evidence in patients with IA, benzodiazepines (diazepam and triazolam) do not appear to be beneficial in improving pain over 24 hours or 1 week." | 4.88 | The efficacy and safety of muscle relaxants in inflammatory arthritis: a Cochrane systematic review. ( Buchbinder, R; Richards, BL; van der Heijde, DM; Whittle, SL, 2012) |
| " She subsequently developed agranulocytosis and cholestatic hepatitis as an adverse reaction to these drugs, later identified as oxyphenbutazone and diazepam." | 3.67 | Agranulocytosis and hepatitis as a result of Mexican drug therapy. ( Jacknowitz, AI; Walker, BK, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Richards, BL | 2 |
| Whittle, SL | 2 |
| Buchbinder, R | 2 |
| van der Heijde, DM | 1 |
| FRASSO, JJ | 1 |
| TARPLEY, EL | 1 |
| Jacknowitz, AI | 1 |
| Walker, BK | 1 |
| Sharma, BK | 1 |
| Haslock, I | 3 |
| Bayley, TR | 1 |
| Hobkirk, D | 1 |
| Rhodes, M | 1 |
| Lussier, A | 1 |
| Myhal, D | 1 |
| Vince, JD | 1 |
| Kremer, D | 1 |
| Scott, WA | 1 |
| Bain, LS | 1 |
3 reviews available for diazepam and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Muscle relaxants for pain management in rheumatoid arthritis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Arthritis, Rheumatoid; Azabicyclo Compou | 2012 |
The efficacy and safety of muscle relaxants in inflammatory arthritis: a Cochrane systematic review.
Topics: Analgesics; Arthritis, Rheumatoid; Diazepam; Drug Therapy, Combination; Humans; Muscle Relaxants, Ce | 2012 |
[Rheumatoid arthritis: treatment in 1972].
Topics: Adrenocorticotropic Hormone; Analgesics; Antimalarials; Arthritis, Rheumatoid; Arthrodesis; Cortison | 1972 |
4 trials available for diazepam and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Night medication in rheumatoid arthritis. III. the use of sulindac.
Topics: Arthritis, Rheumatoid; Benzylidene Compounds; Clinical Trials as Topic; Diazepam; Double-Blind Metho | 1978 |
Night medication in rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Diazepam; Female; Humans; | 1976 |
Night medication in rheumatoid arthritis: II. Combined therapy with indomethacin and diazepam.
Topics: Arthritis, Rheumatoid; Diazepam; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Indomet | 1977 |
Double-blind trial of diazepam in rheumatoid arthritis.
Topics: Adult; Aged; Analgesics; Arthritis, Rheumatoid; Clinical Trials as Topic; Diazepam; Female; Humans; | 1973 |
5 other studies available for diazepam and Arthritis, Rheumatoid
| Article | Year |
|---|---|
[THE USE OF 7-CHLORO-1,3 DIHYDRO-1-METHYL-5-PHENYL-2H-1,4-BENZODIAZEPAM-2-ONE IN ORTHOPEDICS AND TRAUMATOLOGY. PRELIMINARY COMMUNICATION].
Topics: Arthritis; Arthritis, Rheumatoid; Arthroplasty; Diazepam; Fracture Fixation; Fractures, Bone; Hemipl | 1963 |
EVALUATION OF DIAZEPAM (VALIUM) IN THE SYMPTOMATIC TREATMENT OF RHEUMATIC DISORDERS. A CONTROLLED COMPARATIVE STUDY.
Topics: Anxiety; Arthritis; Arthritis, Rheumatoid; Biomedical Research; Carisoprodol; Chlormezanone; Diazepa | 1965 |
Agranulocytosis and hepatitis as a result of Mexican drug therapy.
Topics: Adult; Agranulocytosis; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Diazepam; Dru | 1984 |
Rheumatology.
Topics: Acute Disease; Aged; Analgesics; Arthritis, Rheumatoid; Chronic Disease; Diazepam; Female; Gout; Hum | 1972 |
The use of diazepam in the treatment of musculo-skeletal disorders.
Topics: Adult; Aged; Ankylosis; Arthritis, Rheumatoid; Cervical Vertebrae; Diazepam; Female; Humans; Interve | 1964 |