diazepam has been researched along with Anxiety Neuroses in 338 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A double-blind, placebo-controlled study was carried out in 36 patients diagnosed as suffering from Generalized Anxiety Disorder with associated depressive symptoms to assess the efficacy and tolerability of two unitary doses of etizolam." | 9.06 | Etizolam in the treatment of generalized anxiety disorder: a double-blind study versus placebo. ( Bolino, F; Casacchia, M; Ecari, U, 1990) |
| "The response to diazepam and propranolol hydrochloride was compared in 21 patients who (with one exception) met DSM-III criteria for panic disorder and agoraphobia." | 9.05 | Diazepam and propranolol in panic disorder and agoraphobia. ( Anderson, DJ; Clancy, J; Crowe, RR; Ghoneim, MM; Hinrichs, JV; Noyes, R; Slymen, DJ, 1984) |
| "923) on 8 patients, a double-blind cross-over study of mepiprazol and diazepam was performed in order to compare their effect in the treatment of neurotic disorders, particularly on various forms of anxiety." | 9.04 | [A controlled double-blind crossover study of the efficacy of mepiprazol (EMD 16.923) and of diazepam in the treatment of neurotic disorders]. ( De Buck, R; Pelc, I; Van Durme, R, 1975) |
| "The authors report a case of a 55-year-old man undergoing a triazolam withdrawal syndrome that was recognized and treated with high doses of benzodiazepines, but the patient nevertheless developed seizures." | 7.67 | Seizures following triazolam withdrawal despite benzodiazepine treatment. ( Pawluczyk, S; Schneider, LS; Syapin, PJ, 1987) |
| "Buspirone HCl (Buspar) is a novel anxiolytic agent unrelated to the benzodiazepines or other psychotherapeutic agents." | 6.65 | Buspirone: an anxioselective alternative for the management of anxiety disorders. ( Eison, AS; Eison, MS; Newton, RE; Riblet, LA; Taylor, DP; Temple, DL, 1983) |
| "Quercetin treatment was found to significantly reduce anxiety-like behaviors in mTBI-induced mice." | 5.51 | Quercetin mitigates anxiety-like behavior and normalizes hypothalamus-pituitary-adrenal axis function in a mouse model of mild traumatic brain injury. ( Ghorbanihaghjo, A; Kosari-Nasab, M; Mesgari-Abbasi, M; Salari, AA; Shokouhi, G, 2019) |
| "Data were drawn from 3 double-blind, randomized, placebo-controlled, published treatment trials: alprazolam for patients with premenstrual syndrome (PMS) and diazepam and lorazepam for patients with generalized anxiety disorder (GAD)." | 5.09 | Prior benzodiazepine exposure and benzodiazepine treatment outcome. ( Freeman, EW; Rickels, K, 2000) |
| "The effects of four logarithmically increasing doses of intravenous diazepam or placebo on plasma homovanillic acid (HVA) were determined in benzodiazepine-naive patients with panic disorder (PD) or generalized anxiety disorder (GAD), and in healthy controls." | 5.08 | Effect of benzodiazepines on plasma levels of homovanillic acid in anxious patients and control subjects. ( Cowley, DS; Kramer, GL; Petty, F; Roy-Byrne, PP; Wingerson, DK, 1996) |
| "The acute effects of diazepam on plasma GABA were determined in 18 patients with panic disorder, 13 patients with generalized anxiety disorder and 20 healthy controls." | 5.07 | Effect of acute and chronic benzodiazepines on plasma GABA in anxious patients and controls. ( Cowley, DS; Greenblatt, DJ; Hommer, D; Kramer, GL; Petty, F; Roy-Byrne, PP, 1992) |
| "To examine the effect of treatment on lactate-induced anxiety in a controlled study, we infused 44 panic disorder patients with lactate and placebo before and after eight weeks of double-blind treatment with imipramine, diazepam, or placebo." | 5.07 | Lactate-induced anxiety after imipramine and diazepam treatment. ( Balon, R; Berchou, R; Lycaki, H; Pohl, R, 1994) |
| "A double-blind, placebo-controlled study was carried out in 36 patients diagnosed as suffering from Generalized Anxiety Disorder with associated depressive symptoms to assess the efficacy and tolerability of two unitary doses of etizolam." | 5.06 | Etizolam in the treatment of generalized anxiety disorder: a double-blind study versus placebo. ( Bolino, F; Casacchia, M; Ecari, U, 1990) |
| "A double-blind study was carried out in 30 female patients with generalized anxiety disorders associated with depressive symptoms to compare the effectiveness and tolerability of etizolam and alprazolam." | 5.06 | Etizolam in the treatment of generalized anxiety disorder associated with depressive symptoms. ( Caddeo, S; Ecari, U; Pariante, F, 1989) |
| "52 patients with acute neurotic anxious and psychosomatic syndromes or chronic anxious and vegetative neuroses were treated orally with the combination drug Betamed (1 tablet contain 60 mg bupranolol and 2." | 5.05 | [Betamed in the treatment of psychogenic disorders with a somatic component]. ( Jellinger, K, 1983) |
| "The response to diazepam and propranolol hydrochloride was compared in 21 patients who (with one exception) met DSM-III criteria for panic disorder and agoraphobia." | 5.05 | Diazepam and propranolol in panic disorder and agoraphobia. ( Anderson, DJ; Clancy, J; Crowe, RR; Ghoneim, MM; Hinrichs, JV; Noyes, R; Slymen, DJ, 1984) |
| "Thirty-six patients with generalised anxiety disorder, panic disorder or agoraphobia with panic attacks, diagnosed by DSM-III criteria, were treated with a new non-benzodiazepine anti-anxiety drug, buspirone, and with diazepam and placebo, in a cross-over design." | 5.05 | Anxiety in primary care: is short-term drug treatment appropriate? ( Owen, R; Tyrer, P, 1984) |
| "923) on 8 patients, a double-blind cross-over study of mepiprazol and diazepam was performed in order to compare their effect in the treatment of neurotic disorders, particularly on various forms of anxiety." | 5.04 | [A controlled double-blind crossover study of the efficacy of mepiprazol (EMD 16.923) and of diazepam in the treatment of neurotic disorders]. ( De Buck, R; Pelc, I; Van Durme, R, 1975) |
| "Since only one small study is currently available, there is insufficient evidence to draw any conclusions about the efficacy or safety of valerian compared with placebo or diazepam for anxiety disorders." | 4.83 | Valerian for anxiety disorders. ( Atallah, AN; Miyasaka, LS; Soares, BG, 2006) |
| "Clonazepam has been chosen for further study because in adults it reduced panic attacks and produced few serious side effects." | 3.76 | High anxiety in children. ( Graae, F, 1990) |
| "Clobazam itself has a half-life of 18 hours, but that of the principal metabolite, N-desmethylclobazam, is about 50 hours." | 3.75 | Clobazam: a review of its pharmacological properties and therapeutic use in anxiety. ( Avery, GS; Brogden, RN; Heel, RC; Speight, TM, 1980) |
| "Alprazolam has antidepressant activity and has been shown to be similar in efficacy to imipramine in the treatment of unipolar depression." | 3.75 | Alprazolam: a review of its pharmacodynamic properties and efficacy in the treatment of anxiety and depression. ( Brogden, RN; Dawson, GW; Jue, SG, 1984) |
| " Eighteen patients with panic disorder, 12 patients with generalized anxiety disorder, and 21 control subjects underwent both personality testing and assessment of their sensitivity to diazepam, as measured by slowing of saccadic eye movement velocity." | 3.68 | Personality and benzodiazepine sensitivity in anxious patients and control subjects. ( Cowley, DS; Greenblatt, DJ; Hommer, DW; Roy-Byrne, PP, 1993) |
| " The authors present three patients with alcoholism in whom diagnosis of panic was facilitated by intravenous lactate infusion, and whose symptoms were alleviated by clonazepam." | 3.68 | The diagnosis and treatment of panic disorder in alcoholics: three cases. ( Baron, DH; Ciraulo, DA; Sands, BF; Shader, RI, 1990) |
| "The authors report a case of a 55-year-old man undergoing a triazolam withdrawal syndrome that was recognized and treated with high doses of benzodiazepines, but the patient nevertheless developed seizures." | 3.67 | Seizures following triazolam withdrawal despite benzodiazepine treatment. ( Pawluczyk, S; Schneider, LS; Syapin, PJ, 1987) |
| "Etizolam was well tolerated." | 2.74 | Effects of treatment with etizolam 0.5 mg BID on cognitive performance: a 3-week, multicenter, randomized, double-blind, placebo-controlled, two-treatment, three-period, noninferiority crossover study in patients with anxiety disorder. ( Aguglia, E; Bersani, G; Cesana, BM; De Candia, MP; Di Sciascio, G; Di Sotto, A; Durbano, F; Garavini, A; Mencacci, C; Placidi, G; Rubiera, M, 2009) |
| "The aim of this study is to determine whether long-term use (5-20 years) of therapeutic doses of diazepam (5-20 mg/day) in anxious patients (n = 28) is associated with tolerance to its psychomotor and cognitive effects." | 2.67 | Differential acute psychomotor and cognitive effects of diazepam on long-term benzodiazepine users. ( Bernik, MA; Gorenstein, C; Pompéia, S, 1994) |
| "Benzodiazepines have been prescribed for the treatment of Generalized Anxiety Disorder (GAD) for nearly three decades due to their proven anxiolytic efficacy, despite a considerable side effect and abuse liability profile." | 2.67 | A phase II multicenter dose-finding, efficacy and safety trial of ipsapirone in outpatients with generalized anxiety disorder. ( Cutler, NR; Hesselink, JM; Sramek, JJ, 1994) |
| "Rebound anxiety and withdrawal symptoms were identified in a substantial minority of patients." | 2.67 | Controlled discontinuation of benzodiazepine treatment for patients with panic disorder. ( Cook, B; Garvey, MJ; Noyes, R; Suelzer, M, 1991) |
| " The number of adverse events, particularly drowsiness, was significantly higher with diazepam than with suriclone, particularly 0." | 2.67 | Controlled comparison of the efficacy and safety of four doses of suriclone, diazepam, and placebo in generalized anxiety disorder. ( Ansseau, M; Guillet, P; Jourdain, G; Olié, JP; Stehle, B; von Frenckell, R, 1991) |
| "Both buspirone and diazepam were equally effective in reducing overall anxiety symptoms." | 2.67 | Therapeutic effects and effects on actual driving performance of chronically administered buspirone and diazepam in anxious outpatients. ( van Laar, MW; van Willigenburg, AP; Volkerts, ER, 1992) |
| "Isocarboxazid was replaced by placebo, using double-blind procedure." | 2.67 | Efficacy of combined antidepressant therapy in resistant neurotic disorder. ( Murphy, S; Tyrer, P, 1990) |
| " Dosage escalation by patients is unlikely because of an increased risk of side effects." | 2.67 | A placebo-controlled double-blind multicenter trial of two doses of ipsapirone versus diazepam in generalized anxiety disorder. ( Boyer, WF; Feighner, JP, 1993) |
| "Ipsapirone is an azopirone derivative that selectively interacts with serotonin-1A (5-HT1A) receptors and fails to affect other neurotransmitter receptors." | 2.67 | Efficacy and safety of a putative anxiolytic agent: ipsapirone. ( Albrecht, JW; Borison, RL; Diamond, BI, 1990) |
| "Buspirone was without effect." | 2.66 | A comparison of buspirone, diazepam, and placebo in patients with chronic anxiety states. ( Lader, M; Olajide, D, 1987) |
| "Diazepam was a significantly better antidepressant than moclobemide at four week, although not at eight weeks." | 2.66 | Is diazepam an antidepressant? ( Davis, B; Maguire, KP; Schweitzer, I; Tiller, JW, 1989) |
| "Buspirone has previously been demonstrated to be efficacious in the treatment of anxiety." | 2.66 | Evaluation of buspirone as an antianxiety agent: buspirone and diazepam versus placebo. ( Howarth, BG; Matas, M; Pecknold, JC; Ross, C; Swinson, R; Ungar, W; Vezeau, C, 1989) |
| " Patients were allocated at random to receive one or other dosage regimen for 1 week and treatment could be continued for a further week if necessary." | 2.66 | Multi-centre general practitioner comparative study of controlled-release ('Valrelease') and conventional ('Valium') forms of diazepam in patients suffering from anxiety. ( Skreta, M; Ward, J, 1988) |
| "Diazepam dose levels were lowest for the High group and highest for the Low group." | 2.66 | Early treatment response in anxious outpatients treated with diazepam. ( Downing, RW; Rickels, K, 1985) |
| "1 In an uncontrolled clinical trial, carried out in 11 psychiatric patients with the clinical diagnoses of anxiety neurosis and depressive neurosis, clobazam, a new benzodiazepine preparation, in the dosage range 10-60 mg daily produced statistically significant improvement in the total and both factor scores of the Hamilton Anxiety Scale (HAM-A)." | 2.65 | Clobazam: uncontrolled and standard controlled clinical trials. ( Amin, MM; Ban, TA, 1979) |
| " 2 Clobazam dosage ranged from 5 mg daily (paediatric patients) to 120 mg daily (psychiatric in-patients)." | 2.65 | Review of clinical studies on clobazam. ( Koeppen, D, 1979) |
| " After each week of a flexible dosage treatment with either diazepam, amylobarbitone or placebo anxious patients were assessed by a comprehensive battery of psychiatrist's ratings, subjective tests and psychological performance tasks to detect the clinical and psychological effects of the drugs." | 2.65 | Psychological performance in anxious patients treated with diazepam. ( Lader, M; Tansella, M; Zimmermann-Tansella, C, 1979) |
| "Buspirone was given to 43 patients, diazepam to 46 and placebo to 42." | 2.65 | Buspirone: multicenter efficacy study. ( Wheatley, D, 1982) |
| "Alprazolam was more effective than placebo on all five measures of efficacy and, on several parameters, more effective than diazepam as well." | 2.65 | Anxiolytic efficacy of alprazolam compared to diazepam and placebo. ( Maletzky, BM, 1980) |
| "Ketazolam HS was at least equivalent, and in some respects superior, to diazepam TID with fewer, less severe side effects." | 2.65 | Anxiolytic efficacy and safety of ketazolam compared with diazepam and placebo. ( Kim, KK; Lee, BY; Sirman, A; Trainor, FS, 1980) |
| " It was speculated that the relatively high daily dosage of diazepam may have been contributed to these results." | 2.65 | Clobazam and diazepam in anxiety. ( Brown, AS; Cohen, D; Harris, H; Hurowitz, A; Lindenbaum, EJ; Rickels, K; Ross, HA; Weinstock, R; Wiseman, K; Zal, M, 1981) |
| "Recently, it has been argued that benzodiazepines may not be safe or efficacious beyond 3 months continuous dosage." | 2.65 | Comparison of the therapeutic effect, tolerance and safety of ketazolam and diazepam administered for six months to out-patients with chronic anxiety neurosis. ( Fabre, LF; McLendon, DM; Stephens, AG, 1981) |
| "Both alprazolam and diazepam were superior to placebo for the treatment of the clinical anxiety syndrome throughout a four-week double-blind multiclinic trial in 976 outpatients." | 2.65 | Multicenter double-blind efficacy and safety study comparing alprazolam, diazepam and placebo in clinically anxious patients. ( Cohn, JB, 1981) |
| "Bromazepam was found to be significantly more effective than diazepam with respect to the somatic anxiety factor and the total score for the Hamilton Anxiety Rating Scale and the fear/anxiety factor of the Patient's Self-Rating Symptom Scale." | 2.65 | Bromazepam and diazepam in generalized anxiety: a placebo-controlled study with measurement of drug plasma concentrations. ( Annable, L; Chouinard, G; Fontaine, R; Ogilvie, RI, 1983) |
| " Its use was associated with the lowest incidence of adverse reactions and best dosage compliance." | 2.65 | Bromazepam, a new anxiolytic: a comparative study with diazepam in general practice. Royal College of General Practitioners Medicines Surveillance Organisation. ( , 1984) |
| " Patients were allocated at random to receive 30 mg prazepam or 15 mg diazepam per day, either in divided dosage (3 times) during the day or as a single large dose at night." | 2.65 | A multi-centre comparison of prazepam and diazepam in the treatment of anxiety. ( Dorman, T, 1983) |
| "Buspirone HCl (Buspar) is a novel anxiolytic agent unrelated to the benzodiazepines or other psychotherapeutic agents." | 2.65 | Buspirone: an anxioselective alternative for the management of anxiety disorders. ( Eison, AS; Eison, MS; Newton, RE; Riblet, LA; Taylor, DP; Temple, DL, 1983) |
| "Mianserin was shown to be more effective than diazepam in treating symptoms of both depression and anxiety, with significantly more patients in the mianserin group reaching resolution of symptoms in the time period studied." | 2.65 | Management of mixed affective symptoms in primary care: a critical experiment. ( Ancill, RJ; Davey, A; Kennerson, A; Poyser, J, 1984) |
| "Diazepam, 5 mg, was devoid of adverse psychomotor effects, but diazepam, 10 mg, impaired tracking and divided attention task performance in patients and volunteers alike." | 2.65 | Psychomotor effects of diazepam in anxious patients and healthy volunteers. ( Brendle, A; Erwin, CW; Linnoila, M; Simpson, D, 1983) |
| "Alprazolam was as effective as diazepam in the relief of anxiety as measured by the Hamilton Anxiety Rating Scale, Physician's Global Impressions, Patient's Global Impressions, Hopkins Symptom Checklist and Target Symptoms Record." | 2.65 | Double-blind comparison of alprazolam and diazepam for subchronic withdrawal from alcohol. ( Kolin, IS; Linet, OI, 1981) |
| "Diazepam was more effective than placebo or propranolol." | 2.65 | Diazepam, propranolol and their combination in the management of chronic anxiety. ( Edwards, JG; Hallstrom, C; Lader, M; Treasaden, I, 1981) |
| "Diazepam response was much less affected by these variables." | 2.64 | Diazepam and halazepam in anxiety: some prognostic indicators. ( Case, WG; Chung, H; Downing, RW; Rickels, K; Vlahovich, J, 1978) |
| " Clobazam was administered in three divided doses of 30 to 40 mg/day, while diazepam was administered in three divided doses of 15 to 20 mg/day, following a fixed dosage schedule." | 2.64 | Clobazam versus diazepam--a double-blind study in anxiety neurosis. ( Apte, JS; Doongaji, DR; Khare, CB; Lakdawala, PD; Sheth, A; Thatte, SS, 1978) |
| "Buspirone was the first novel drug to emerge from this search in almost thirty years." | 2.38 | Serotonin agents in anxiety. ( Taylor, DP, 1990) |
| "Salicylic acid (SA) is a natural phenolic compound in plants with many beneficial effects for humans." | 1.72 | The anxiolytic effect of salicylic acid is mediated via the GABAergic system in the fear potentiated plus maze behavior in rats. ( Abbasnejad, M; Esmaeli-Mahani, S; Moghaddam Dizaj Herik, H; Motaghi, S; Sepehri, G, 2022) |
| "Quercetin treatment was found to significantly reduce anxiety-like behaviors in mTBI-induced mice." | 1.51 | Quercetin mitigates anxiety-like behavior and normalizes hypothalamus-pituitary-adrenal axis function in a mouse model of mild traumatic brain injury. ( Ghorbanihaghjo, A; Kosari-Nasab, M; Mesgari-Abbasi, M; Salari, AA; Shokouhi, G, 2019) |
| "Diazepam was used as a reference anxiolytic drug." | 1.46 | A Fatty Acids Mixture Reduces Anxiety-Like Behaviors in Infant Rats Mediated by GABA ( Bernal-Morales, B; Contreras, CM; Cueto-Escobedo, J; Guillén-Ruiz, G; Rodríguez-Landa, JF, 2017) |
| " In a first series of experiments using hemizygous tamoxifen-induced genetic inactivation of a floxed γ2 genomic locus we show that reducing the gene dosage at postnatal days (P)13/14 but not P27/28 results in altered behavior in both of these tests in adulthood, reminiscent of the anxious-depressive phenotype previously described for global heterozygous mice." | 1.38 | GABAergic control of critical developmental periods for anxiety- and depression-related behavior in mice. ( Fuchs, T; Luscher, B; Sahir, N; Shen, Q, 2012) |
| "The effects of GB-115 dipeptide, a retroanalog of endogenous CCK-4, on the behavioral indices in "elevated plus maze" (EPM) test and on the content of biogenic amines in the brain structures after discontinuation of a chronic administration of benzodiazepine (BZ) derivatives phenazepam (2." | 1.37 | [Effect of GB-115 dipeptide on anxiety in rats with model benzodiazepine withdrawal syndrome]. ( Gudasheva, TA; Kadnikov, IA; Kolik, LG; Seredenin, SB; Zhukov, VN, 2011) |
| "pramipexole) known to produce compulsive behaviors in humans would increase marble burying." | 1.37 | Pharmacological evaluation of the adequacy of marble burying as an animal model of compulsion and/or anxiety. ( Jimenez-Gomez, C; Osentoski, A; Woods, JH, 2011) |
| "A series of high-affinity GABA(A) agonists with good oral bioavailability in rat and dog and functional selectivity for the GABA(A)alpha2 and -alpha3 subtypes is reported." | 1.33 | Imidazo[1,2-a]pyrimidines as functionally selective and orally bioavailable GABA(A)alpha2/alpha3 binding site agonists for the treatment of anxiety disorders. ( Atack, JR; Blackaby, WP; Brown, N; Castro, JL; Cook, SM; Crawforth, JM; Ferris, P; Goodacre, SC; Hallett, DJ; Kelly, S; Lewis, RT; Marshall, G; Owens, AP; Pike, A; Smith, AJ; Sohal, B; Stanley, J; Street, LJ; Wafford, KA, 2006) |
| " It is suggested that the chronic administration of the benzodiazepine may have induced changes in the brain that interfered with ECT." | 1.28 | Do benzodiazepines interfere with the action of electroconvulsive therapy? ( Cohen, SI; Lawton, C, 1992) |
| "Pretreatment with clonidine hydrochloride and propranolol hydrochloride, both of which have been reported to have anxiolytic actions in man, attenuated only selective aspects of the response to beta-CCE." | 1.27 | A benzodiazepine receptor-mediated model of anxiety. Studies in nonhuman primates and clinical implications. ( Aloi, J; Insel, TR; Jimerson, DC; Ninan, PT; Paul, SM; Skolnick, P, 1984) |
| " Serum nordiazepam is a more consistent index of dosage after chronic therapy than serum diazepam because it has a longer elimination half-time." | 1.27 | Value of serum diazepam and nordiazepam measurements in anxious patients. ( Dawling, S; Flanagan, RJ; Moreton, K; Riley, P; Treasaden, I; Tyrer, P, 1984) |
| " Significant relationships were found between the clinical effect and the plasma concentrations of D and DD, respectively; a curvilinear relationship resulted if the dosage was disregarded, but within the individual dosage groups the relationship was found to be linear." | 1.27 | Diazepam and desmethyldiazepam plasma concentrations in chronic anxious outpatients. ( Case, WG; Dixon, R; Downing, RW; Fridman, R; Rickels, K, 1984) |
| " Caution should be exercised in long-term use of benzodiazepines in susceptible individuals." | 1.27 | Delusional depression following benzodiazepine withdrawal. ( Eales, M; Joyce, E; Keshavan, MS; Moodley, P; Yeragani, VK, 1988) |
| " The findings of modest diazepam dose and plasma concentration (mean=324 ng/ml) and of a trend toward a positive correlation between anxiety level and both dose and plasma level suggest inadequate dosage as a more likely explanation for the subjects' continued anxiety." | 1.26 | Chronic diazepam treatment in psychiatric outpatients. ( Battey, YW; Greenblatt, DJ; Laughren, TP, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 232 (68.64) | 18.7374 |
| 1990's | 57 (16.86) | 18.2507 |
| 2000's | 30 (8.88) | 29.6817 |
| 2010's | 18 (5.33) | 24.3611 |
| 2020's | 1 (0.30) | 2.80 |
| Authors | Studies |
|---|---|
| Goodacre, SC | 1 |
| Street, LJ | 1 |
| Hallett, DJ | 1 |
| Crawforth, JM | 1 |
| Kelly, S | 1 |
| Owens, AP | 1 |
| Blackaby, WP | 1 |
| Lewis, RT | 1 |
| Stanley, J | 1 |
| Smith, AJ | 1 |
| Ferris, P | 1 |
| Sohal, B | 1 |
| Cook, SM | 1 |
| Pike, A | 1 |
| Brown, N | 1 |
| Wafford, KA | 1 |
| Marshall, G | 1 |
| Castro, JL | 1 |
| Atack, JR | 1 |
| Motaghi, S | 1 |
| Moghaddam Dizaj Herik, H | 1 |
| Sepehri, G | 1 |
| Abbasnejad, M | 1 |
| Esmaeli-Mahani, S | 1 |
| Yoshizawa, K | 1 |
| Okumura, A | 1 |
| Nakashima, K | 1 |
| Sato, T | 1 |
| Higashi, T | 1 |
| Bernal-Morales, B | 1 |
| Cueto-Escobedo, J | 1 |
| Guillén-Ruiz, G | 1 |
| Rodríguez-Landa, JF | 1 |
| Contreras, CM | 1 |
| Kosari-Nasab, M | 1 |
| Shokouhi, G | 1 |
| Ghorbanihaghjo, A | 1 |
| Mesgari-Abbasi, M | 1 |
| Salari, AA | 1 |
| Nkogho Mengue, PG | 1 |
| Abdous, B | 1 |
| Berbiche, D | 1 |
| Preville, M | 1 |
| Voyer, P | 1 |
| Calcaterra, NE | 1 |
| Barrow, JC | 1 |
| de Rezende, VB | 1 |
| Rosa, DV | 1 |
| Comim, CM | 1 |
| Magno, LA | 1 |
| Rodrigues, AL | 1 |
| Vidigal, P | 1 |
| Jeromin, A | 1 |
| Quevedo, J | 1 |
| Romano-Silva, MA | 1 |
| Gupta, D | 1 |
| Radhakrishnan, M | 1 |
| Kurhe, Y | 1 |
| Vogt, MA | 1 |
| Mallien, AS | 1 |
| Pfeiffer, N | 1 |
| Inta, I | 1 |
| Gass, P | 1 |
| Inta, D | 1 |
| O'Connor, KA | 1 |
| Feustel, PJ | 1 |
| Ramirez-Zamora, A | 1 |
| Molho, E | 1 |
| Pilitsis, JG | 1 |
| Shin, DS | 1 |
| James, AO | 1 |
| Nicholson, TR | 1 |
| Hill, R | 1 |
| Bearn, J | 1 |
| Taguchi, R | 1 |
| Shikata, K | 1 |
| Furuya, Y | 1 |
| Ino, M | 1 |
| Shin, K | 1 |
| Shibata, H | 1 |
| Junqueira-Ayres, DD | 1 |
| Asth, L | 1 |
| Ayres, AS | 1 |
| Lobão-Soares, B | 1 |
| Soares-Rachetti, VP | 1 |
| Gavioli, EC | 1 |
| Barros, M | 1 |
| Maior, RS | 1 |
| Huston, JP | 1 |
| Tomaz, C | 1 |
| de Lusignan, S | 1 |
| Buxton, N | 1 |
| Kent, A | 1 |
| De Candia, MP | 1 |
| Di Sciascio, G | 1 |
| Durbano, F | 1 |
| Mencacci, C | 1 |
| Rubiera, M | 1 |
| Aguglia, E | 2 |
| Garavini, A | 1 |
| Bersani, G | 1 |
| Di Sotto, A | 1 |
| Placidi, G | 1 |
| Cesana, BM | 1 |
| Saiyudthong, S | 1 |
| Marsden, CA | 1 |
| Kinsey, SG | 1 |
| O'Neal, ST | 1 |
| Long, JZ | 1 |
| Cravatt, BF | 1 |
| Lichtman, AH | 1 |
| Jimenez-Gomez, C | 1 |
| Osentoski, A | 1 |
| Woods, JH | 1 |
| Kolik, LG | 1 |
| Kadnikov, IA | 1 |
| Zhukov, VN | 1 |
| Gudasheva, TA | 1 |
| Seredenin, SB | 1 |
| Shen, Q | 1 |
| Fuchs, T | 1 |
| Sahir, N | 1 |
| Luscher, B | 1 |
| Andreatini, R | 1 |
| Sartori, VA | 1 |
| Seabra, ML | 1 |
| Leite, JR | 1 |
| Santarelli, L | 1 |
| Gobbi, G | 1 |
| Blier, P | 1 |
| Hen, R | 1 |
| Hackett, D | 1 |
| Haudiquet, V | 1 |
| Salinas, E | 1 |
| Falissard, B | 1 |
| Lepicard, EM | 1 |
| Venault, P | 1 |
| Negroni, J | 1 |
| Perez-Diaz, F | 1 |
| Joubert, C | 1 |
| Nosten-Bertrand, M | 1 |
| Berthoz, A | 1 |
| Chapouthier, G | 1 |
| Ataoglu, A | 1 |
| Ozcetin, A | 1 |
| Icmeli, C | 1 |
| Ozbulut, O | 1 |
| Inada, T | 1 |
| Nozaki, S | 1 |
| Inagaki, A | 1 |
| Furukawa, TA | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Mood Disorder Cohort Research Consortium (MDCRC) in Korea[NCT03088657] | 500 participants (Anticipated) | Observational [Patient Registry] | 2015-09-30 | Recruiting | |||
| Verapamil as Adjunctive Seizure Therapy for Children and Young Adults With Dravet Syndrome[NCT01607073] | Phase 2 | 2 participants (Actual) | Interventional | 2012-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The secondary outcome measure is the change in number of absence seizures from Week 8 (Baseline) to Week 12 (NCT01607073)
Timeframe: Week 8 to Week 12
| Intervention | Abscence seizures (Number) |
|---|---|
| Week 8 Baseline | 165 |
| Week 12 Verapamil 4mg/kg/Day | 101 |
The primary study endpoint is the change in number of seizures from baseline. Since we only had one participant finish the study, the endpoint was changed to Week 12 visit. Participants were on verapamil for 4 weeks at Week 12. (NCT01607073)
Timeframe: Week 8 (baseline) to Week 12
| Intervention | General tonic-clonic seizures (Number) |
|---|---|
| Week 8 Baseline | 39 |
| Week 12 Verapamil 4mg/kg/Day | 14 |
The secondary outcome is the change in number of myoclonic seizures between baseline Week 8 visit and Week 12 visit. (NCT01607073)
Timeframe: Week 8 (baseline) to Week 12
| Intervention | Myoclonic seizures (Number) |
|---|---|
| Week 8 Baseline | 116 |
| Week 12 Verapamil 4mg/kg/Day | 175 |
21 reviews available for diazepam and Anxiety Neuroses
| Article | Year |
|---|---|
Classics in chemical neuroscience: diazepam (valium).
Topics: Anxiety Disorders; Diazepam; Dose-Response Relationship, Drug; Drug Design; Drug Overdose; Humans; R | 2014 |
Predatory stress as an experimental strategy to measure fear and anxiety-related behaviors in non-human primates.
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Behavior, Animal; Diazepam; Disease Models, Animal; | 2008 |
Behavioral and physiologic effects of genetic or pharmacologic inactivation of the substance P receptor (NK1).
Topics: Affect; Animals; Anxiety Disorders; Aprepitant; Autoreceptors; Behavior, Animal; Corticosterone; Dia | 2002 |
Efficacy of diazepam as an anti-anxiety agent: meta-analysis of double-blind, randomized controlled trials carried out in Japan.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Humans; Randomized Controlled Trials as Topic; Tre | 2003 |
Valerian for anxiety disorders.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Humans; Phytotherapy; Pilot Projects; Valerian | 2006 |
Clobazam: a review of its pharmacological properties and therapeutic use in anxiety.
Topics: Adolescent; Anti-Anxiety Agents; Anticonvulsants; Anxiety Disorders; Benzodiazepines; Benzodiazepino | 1980 |
Lorazepam: a review of its clinical pharmacological properties and therapeutic uses.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Central Nervous System; Clinical Trials as Topic; Diazepam; | 1981 |
The mechanism(s) of action of the benzodiazepines.
Topics: Adenosine; Animals; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Caffeine; Carbolines; C | 1981 |
Alprazolam: a review of its pharmacodynamic properties and efficacy in the treatment of anxiety and depression.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Benzodiazepines; | 1984 |
Effects of valium and librium on human psychomotor and cognitive functions.
Topics: Aged; Animals; Anxiety Disorders; Automobile Driving; Chlordiazepoxide; Cognition; Diazepam; Eye Mov | 1984 |
Approach to the dizzy patient.
Topics: Anxiety Disorders; Brain Diseases; Diazepam; Dizziness; Heart Diseases; Humans; Meclizine; Meniere D | 1994 |
[Neuroendocrine effects of benzodiazepines].
Topics: Adrenocorticotropic Hormone; Animals; Anxiety Disorders; Benzodiazepines; Diazepam; Endocrine Glands | 1994 |
Stress, neuropsychiatric disorders and immunological effects exerted by benzodiazepines.
Topics: Adjuvants, Immunologic; Alprazolam; Animals; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines | 1998 |
Short-acting versus long-acting benzodiazepines: discontinuation effects in panic disorders.
Topics: Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Drug Administration Schedule; Humans; | 1990 |
High anxiety in children.
Topics: Adult; Age Factors; Anxiety Disorders; Child; Clinical Trials as Topic; Clonazepam; Diazepam; Humans | 1990 |
Serotonin agents in anxiety.
Topics: Antidepressive Agents; Anxiety Disorders; Buspirone; Diazepam; Humans; Serotonin | 1990 |
A pooled, double-blind comparison of the effects of buspirone, diazepam and placebo in women with chronic anxiety.
Topics: Adolescent; Adult; Aged; Anxiety Disorders; Buspirone; Clinical Trials as Topic; Diazepam; Double-Bl | 1989 |
A sound basis for the use of benzodiazepines.
Topics: Anesthesia; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Drug Utilization; Epilepsy; Humans; In | 1985 |
Review of the side-effect profile of buspirone.
Topics: Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Buspirone; Clinical Trials as T | 1986 |
Intravenous sedation-a review.
Topics: Administration, Oral; Adolescent; Age Factors; Aged; Analgesia; Anesthesia, Dental; Anxiety Disorder | 1974 |
[Psychopharmacological agent in anxiety states].
Topics: Antidepressive Agents; Anxiety Disorders; Bipolar Disorder; Depression; Diazepam; Humans; Psychother | 1970 |
172 trials available for diazepam and Anxiety Neuroses
| Article | Year |
|---|---|
Effects of treatment with etizolam 0.5 mg BID on cognitive performance: a 3-week, multicenter, randomized, double-blind, placebo-controlled, two-treatment, three-period, noninferiority crossover study in patients with anxiety disorder.
Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Anxiety Disorders; Cognition; Cross-Over Studies; | 2009 |
Effect of valepotriates (valerian extract) in generalized anxiety disorder: a randomized placebo-controlled pilot study.
Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Double-Blind Method; | 2002 |
A method for controlling for a high placebo response rate in a comparison of venlafaxine XR and diazepam in the short-term treatment of patients with generalised anxiety disorder.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Cyclohexanols; Diazepam; Dose-Response Relationship, | 2003 |
Statistical considerations about the question of a selection of discriminating centres in the analysis of clinical trial. In response to the paper: "A method for controlling for a high response rate in a comparison of venlafaxine XR and diazepan in the sh
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Bias; Cyclohexanols; Data Collection; Diazepam; Dose- | 2003 |
Cortisol response to diazepam: its relationship to age, dose, duration of treatment, and presence of generalized anxiety disorder.
Topics: Adult; Age Factors; Aged; Anti-Anxiety Agents; Anxiety Disorders; Cross-Over Studies; Diazepam; Dose | 2005 |
Selective anxiolysis produced by ocinaplon, a GABA(A) receptor modulator.
Topics: Adult; Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety Disorders; Behavior, Animal; Condition | 2005 |
Reinforcing effects of diazepam under anxiogenic conditions in individuals with social anxiety.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anxiety Disorders; Computer User Training; Diagnostic and St | 2005 |
Anxiolytic efficacy of alprazolam compared to diazepam and placebo.
Topics: Adolescent; Adult; Aged; Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Clinic | 1980 |
Anxiolytic efficacy and safety of ketazolam compared with diazepam and placebo.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Benzodiazepinones; | 1980 |
Clobazam: a review of its pharmacological properties and therapeutic use in anxiety.
Topics: Adolescent; Anti-Anxiety Agents; Anticonvulsants; Anxiety Disorders; Benzodiazepines; Benzodiazepino | 1980 |
Ketazolam compared to diazepam and placebo in the treatment of anxiety.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Benzodiazepinones; | 1980 |
Double-blind comparison of ketazolam, diazepam and placebo in once-a-day vs t.i.d. dosing.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Benzodiazepinones; | 1980 |
Clobazam and diazepam in anxiety.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Benzodiazepinones; Clinical Trials a | 1981 |
Comparison of the therapeutic effect, tolerance and safety of ketazolam and diazepam administered for six months to out-patients with chronic anxiety neurosis.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; B | 1981 |
A comparison of prazepam, diazepam, lorazepam and placebo in anxious outpatients in non-psychiatric private practices.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Depressive Disorder; Diazepam; Doub | 1981 |
Lorazepam: a review of its clinical pharmacological properties and therapeutic uses.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Central Nervous System; Clinical Trials as Topic; Diazepam; | 1981 |
Multicenter double-blind efficacy and safety study comparing alprazolam, diazepam and placebo in clinically anxious patients.
Topics: Adolescent; Adult; Aged; Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Clinic | 1981 |
Recent advances in anxiolytic therapy.
Topics: Adult; Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Buspirone; Clinical Tria | 1981 |
A therapeutic and discontinuation study of clobazam and diazepam in anxiety neurosis.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Benzodiazepinones; Clinical Trials a | 1982 |
The significance of treatment effects across several independent studies.
Topics: Antipsychotic Agents; Anxiety Disorders; Arousal; Clinical Trials as Topic; Diazepam; Dihydroergotox | 1981 |
A controlled clinical trial of alprazolam for the treatment of anxiety.
Topics: Adult; Alprazolam; Ambulatory Care; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Clinica | 1983 |
The side effect profile of buspirone in comparison to active controls and placebo.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Buspirone; Clinical Trials as Topic; Clorazepate Dipotassium | 1982 |
A double-blind comparison of buspirone and diazepam in outpatients with generalized anxiety disorder.
Topics: Adolescent; Adult; Ambulatory Care; Anti-Anxiety Agents; Anxiety Disorders; Buspirone; Clinical Tria | 1982 |
Buspirone and diazepam in anxiety: a controlled study.
Topics: Adult; Ambulatory Care; Anti-Anxiety Agents; Anxiety Disorders; Buspirone; Clinical Trials as Topic; | 1982 |
Buspirone: multicenter efficacy study.
Topics: Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Buspirone; Clinical Trials as Topic; Diazepam; | 1982 |
Drug interactions in controlled clinical trials.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Buspirone; Clinical Trials as Topic; Clorazepate Dipotassium | 1982 |
Bromazepam and diazepam in generalized anxiety: a placebo-controlled study with measurement of drug plasma concentrations.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Bromazepam; Clinical Trials as Topic; Diazepam; Doubl | 1983 |
A placebo-controlled, double-blind comparison of clobazam and diazepam in the treatment of anxiety.
Topics: Adult; Ambulatory Care; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Benzodiazepinones; | 1983 |
Benzodiazepine effect on information processing in generalized anxiety disorder.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Bromazepam; Clinical Trials as Topic; Diazepam; Doubl | 1983 |
New concepts in benzodiazepine therapy: rebound anxiety and new indications for the more potent benzodiazepines.
Topics: Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Bipolar Disorder; Bromazepam; C | 1983 |
Alprazolam: a review of its pharmacodynamic properties and efficacy in the treatment of anxiety and depression.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Benzodiazepines; | 1984 |
Bromazepam and diazepam in generalized anxiety: a placebo-controlled study of efficacy and withdrawal.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Bromazepam; Clinical Trials as Topic; Diazepam; Doubl | 1984 |
Rebound anxiety in anxious patients after abrupt withdrawal of benzodiazepine treatment.
Topics: Acute Disease; Adult; Anti-Anxiety Agents; Anxiety Disorders; Bromazepam; Clinical Trials as Topic; | 1984 |
Alprazolam and diazepam in the treatment of generalized anxiety.
Topics: Adult; Aged; Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Clinical Trials as | 1984 |
Bromazepam, a new anxiolytic: a comparative study with diazepam in general practice. Royal College of General Practitioners Medicines Surveillance Organisation.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Bromazepam; Diazepam; Double-Blind | 1984 |
Long-term diazepam therapy and clinical outcome.
Topics: Adult; Anxiety Disorders; Chronic Disease; Clinical Trials as Topic; Diazepam; Double-Blind Method; | 1983 |
Intramuscular lorazepam. A double-blind comparison with diazepam and placebo.
Topics: Adolescent; Adult; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Double-Blind Method; Femal | 1983 |
A multi-centre comparison of prazepam and diazepam in the treatment of anxiety.
Topics: Adolescent; Adult; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Female; Humans; Male; Midd | 1983 |
[Betamed in the treatment of psychogenic disorders with a somatic component].
Topics: Adolescent; Adult; Aged; Anxiety Disorders; Bupranolol; Clinical Trials as Topic; Diazepam; Drug Adm | 1983 |
Buspirone: an anxioselective alternative for the management of anxiety disorders.
Topics: Aggression; Animals; Anxiety Disorders; Arousal; Avoidance Learning; Buspirone; Clinical Trials as T | 1983 |
Diazepam and propranolol in panic disorder and agoraphobia.
Topics: Adult; Agoraphobia; Anxiety Disorders; Clinical Trials as Topic; Depression; Diazepam; Double-Blind | 1984 |
Anxiety in primary care: is short-term drug treatment appropriate?
Topics: Adult; Agoraphobia; Anxiety Disorders; Buspirone; Clinical Trials as Topic; Diazepam; Female; Humans | 1984 |
Management of mixed affective symptoms in primary care: a critical experiment.
Topics: Adolescent; Adult; Aged; Anxiety Disorders; Clinical Trials as Topic; Depressive Disorder; Diazepam; | 1984 |
Psychomotor effects of diazepam in anxious patients and healthy volunteers.
Topics: Adult; Anxiety Disorders; Diazepam; Dose-Response Relationship, Drug; Female; Humans; Male; Nordazep | 1983 |
Withdrawal responses to abrupt discontinuation of desmethyldiazepam.
Topics: Acute Disease; Adult; Anxiety Disorders; Clinical Trials as Topic; Depression; Diazepam; Feeding and | 1984 |
A controlled comparison of relaxation and diazepam in panic disorder.
Topics: Adolescent; Adult; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Evaluation Studies as Topi | 1982 |
Comparison of buspirone in two separate studies.
Topics: Adult; Ambulatory Care; Anxiety Disorders; Buspirone; Clinical Trials as Topic; Clorazepate Dipotass | 1982 |
Relationship of diazepam serum level to antianxiety effects.
Topics: Adult; Anxiety Disorders; Chromatography, Gas; Chromatography, High Pressure Liquid; Diazepam; Femal | 1982 |
Single daily dose treatment of anxiety with clobazam: a double-blind study versus normal multiple-dose treatment with diazepam.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Benzodiazepinones; | 1980 |
[Randomized double-blind study of loxapine as compared with diazepam in therapy of patients with anxiety neuroses].
Topics: Adult; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Dibenzoxazepines; Double-Blind Method; | 1980 |
Double-blind comparison of alprazolam and diazepam for subchronic withdrawal from alcohol.
Topics: Adolescent; Adult; Aged; Alcoholism; Alprazolam; Anxiety Disorders; Benzodiazepines; Clinical Trials | 1981 |
[A double blind trial : oxprenolol/diazepam (author's transl)].
Topics: Anxiety Disorders; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female; Humans; Male; Ox | 1981 |
Diazepam, propranolol and their combination in the management of chronic anxiety.
Topics: Adult; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Double-Blind Method; Drug Therapy, Com | 1981 |
Anxiety: differential diagnosis and treatment from a biologic perspective.
Topics: Agoraphobia; Anxiety Disorders; Clinical Trials as Topic; Diagnosis, Differential; Diazepam; Double- | 1981 |
Coffee consumption, cigarette smoking and reporting of drowsiness in anxious patients treated with benzodiazepines or placebo.
Topics: Anxiety Disorders; Chlordiazepoxide; Clinical Trials as Topic; Coffee; Diazepam; Double-Blind Method | 1981 |
Successful treatment of anxiety with a single night-time dose of chlormezanone: double-blind comparison with diazepam.
Topics: Adult; Anxiety Disorders; Chlormezanone; Diazepam; Double-Blind Method; Drug Administration Schedule | 1982 |
Neurotic illness and its response to anxiolytic and antidepressant treatment.
Topics: Adjustment Disorders; Adult; Amitriptyline; Anxiety Disorders; Diazepam; Female; Humans; Male; Psych | 1980 |
Anxiolytics' effects on the actual driving performance of patients and healthy volunteers in a standardized test. An integration of three studies.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Attention; Automobile Driving; Cross-Over Studies; Diazepam; | 1995 |
Differential acute psychomotor and cognitive effects of diazepam on long-term benzodiazepine users.
Topics: Adult; Anxiety Disorders; Cognition; Depressive Disorder; Diazepam; Dose-Response Relationship, Drug | 1994 |
A placebo-controlled double-blind multicenter trial of two doses of ipsapirone versus diazepam in generalized anxiety disorder.
Topics: Ambulatory Care; Analysis of Variance; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Double-Blin | 1993 |
A phase II multicenter dose-finding, efficacy and safety trial of ipsapirone in outpatients with generalized anxiety disorder.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Double-Blind Method; Female; Humans; Male; | 1994 |
Antidepressants for the treatment of generalized anxiety disorder. A placebo-controlled comparison of imipramine, trazodone, and diazepam.
Topics: Adult; Aged; Anxiety Disorders; Diazepam; Double-Blind Method; Drug Administration Schedule; Female; | 1993 |
Baclofen administration for the treatment of affective disorders in alcoholic patients.
Topics: Administration, Oral; Adult; Alcoholism; Amitriptyline; Anxiety Disorders; Baclofen; Blood Platelets | 1993 |
The Nottingham study of neurotic disorder. Effect of personality status on response to drug treatment, cognitive therapy and self-help over two years.
Topics: Adult; Anxiety Disorders; Cognitive Behavioral Therapy; Depressive Disorder; Diazepam; Dothiepin; Fe | 1993 |
Treatment, discontinuation, and psychomotor effects of diazepam in women with generalized anxiety disorder.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Double-Blind Method; Female; Humans; Psycho | 1996 |
Changes in "withdrawal symptoms" following discontinuation of low-dose diazepam.
Topics: Adult; Agoraphobia; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Double-Blind Method; Female; H | 1996 |
Effect of benzodiazepines on plasma levels of homovanillic acid in anxious patients and control subjects.
Topics: Adult; Anxiety Disorders; Benzodiazepines; Diazepam; Dopamine; Female; Homovanillic Acid; Humans; Ma | 1996 |
Lactate-induced anxiety after imipramine and diazepam treatment.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety Disorders; Arousal | 1994 |
Efficacy of ondansetron in the treatment of generalized anxiety disorder.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Dose-Response Relationship, Drug; Double-Bl | 1997 |
A double-blind, placebo-controlled trial of abecarnil and diazepam in the treatment of patients with generalized anxiety disorder.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Anti-Anxiety Agents; Anxiety Disorders; Carbolines; D | 2000 |
Prior benzodiazepine exposure and benzodiazepine treatment outcome.
Topics: Alprazolam; Anxiety Disorders; Benzodiazepines; Diazepam; Dose-Response Relationship, Drug; Double-B | 2000 |
[Double-blind comparison of parsalmide and diazepam in anxious and depressive neurotic syndromes].
Topics: Adjustment Disorders; Adult; Aged; Anti-Anxiety Agents; Anti-Inflammatory Agents, Non-Steroidal; Anx | 1976 |
Double-blind cross-over clinical comparison of two 2'-chloro benzodiazepines: 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one (chlordesmethyldiazepam) versus 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one (
Topics: Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Brief Psychiatric Rating Scale; Clinical Trials | 1977 |
Halazepam and diazepam in neurotic anxiety: a double-blind study.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Clinical Trials as Topic; Diazepam; | 1977 |
Diazepam and halazepam in anxiety: some prognostic indicators.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Clinical Trials as Topic; Diazepam; | 1978 |
A double-blind comparison of clobazam and diazepam in the treatment of anxiety neurosis.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Doubl | 1978 |
Clobazam versus diazepam--a double-blind study in anxiety neurosis.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Double-Blind Meth | 1978 |
Clobazam versus diazepam: a double-blind study in anxiety neurosis [proceedings].
Topics: Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Humans; Motor S | 1979 |
Clobazam: uncontrolled and standard controlled clinical trials.
Topics: Adjustment Disorders; Adult; Anti-Anxiety Agents; Anxiety Disorders; Clinical Trials as Topic; Diaze | 1979 |
Review of clinical studies on clobazam.
Topics: Adult; Alcoholism; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Child; Clinical Trials as Topic; | 1979 |
Camazepam versus diazepam: a double-blind trial on psychoneurotic patients.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Carbamates; Clinical Trials as Topi | 1975 |
A comparison between bromazepam (Ro 5-3350, Lexotan) and diazepam (Valium) in anxiety neurosis. A controlled, double-blind clinical trial.
Topics: Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Bromazepam; Clinical Trials as Topic; Diazepam; | 1975 |
Clinical and physiological assessment of chlorazepate, diazepam and placebo in anxious neurotics.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anxiety Disorders; Arousal; Blood Pressure; Clinical Trials | 1975 |
A clinical trial of phenelzine in anxiety depressive and phobic neuroses.
Topics: Adjustment Disorders; Adolescent; Adult; Aged; Agoraphobia; Anxiety Disorders; Clinical Trials as To | 1977 |
A double-blind comparative study of desipramine hydrochloride and diazepam in the control of mixed anxiety/depression symptomatology.
Topics: Adjustment Disorders; Adolescent; Adult; Anxiety Disorders; Clinical Trials as Topic; Desipramine; D | 1979 |
The comparative efficacy of buspirone and diazepam in the treatment of anxiety.
Topics: Adult; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Double-Blind Method; Drug Evaluation; | 1979 |
Psychological performance in anxious patients treated with diazepam.
Topics: Adult; Amobarbital; Anxiety Disorders; Behavior; Clinical Trials as Topic; Crisis Intervention; Diaz | 1979 |
[A controlled double-blind crossover study of the efficacy of mepiprazol (EMD 16.923) and of diazepam in the treatment of neurotic disorders].
Topics: Adult; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Female; Humans; Male; Middle Aged; Neu | 1975 |
Application of the neuroleptic pimozide (ORAP-R 6238) for tranquilizer indications in a controlled study.
Topics: Adult; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Female; Humans; Male; Middle Aged; Pim | 1976 |
A comparison of the effects of propranolol and diazepam in alcoholics.
Topics: Adult; Alcoholism; Anxiety Disorders; Clinical Trials as Topic; Depression; Diazepam; Humans; Male; | 1976 |
Modification by diazepam or thioridazine of the psychomotor skills related to driving: a subacute trial in neurotic out-patients.
Topics: Adult; Ambulatory Care; Anxiety Disorders; Attention; Automobile Driving; Diazepam; Female; Humans; | 1976 |
N-desmethyldiazepam and amylobarbitone sodium as hypnotics in anxious patients. Plasma levels, clinical efficacy and residual effects.
Topics: Adult; Amobarbital; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Female; Humans; Hypnotics | 1975 |
Effects of beta-blocking drugs in alcohol withdrawal: a double-blind comparative study with propranolol and diazepam.
Topics: Adrenergic beta-Antagonists; Adult; Analysis of Variance; Anxiety Disorders; Diazepam; Double-Blind | 1992 |
Effect of acute and chronic benzodiazepines on plasma GABA in anxious patients and controls.
Topics: Adult; Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; gamma-Aminobutyric Acid; Humans | 1992 |
The general neurotic syndrome: a coaxial diagnosis of anxiety, depression and personality disorder.
Topics: Adjustment Disorders; Anxiety Disorders; Cognitive Behavioral Therapy; Depressive Disorder; Diazepam | 1992 |
Therapeutic effects and effects on actual driving performance of chronically administered buspirone and diazepam in anxious outpatients.
Topics: Adolescent; Adult; Affect; Anxiety Disorders; Arousal; Attention; Automobile Driver Examination; Aut | 1992 |
Neuroendocrine effects of diazepam in panic and generalized anxiety disorders.
Topics: Adrenocorticotropic Hormone; Adult; Anxiety Disorders; Diazepam; Female; Growth Hormone; Humans; Hyd | 1991 |
[Evaluation of the effectiveness of drug therapy of autonomic paroxysms in relation to the variability of cardiac rhythm].
Topics: Adult; Anxiety Disorders; Autonomic Nervous System Diseases; Depressive Disorder; Diazepam; Heart Ra | 1991 |
Evaluation of the effects of diazepam and an experimental anti-anxiety drug on regional cerebral blood flow.
Topics: Adult; Anti-Anxiety Agents; Antipsychotic Agents; Anxiety Disorders; Cerebral Cortex; Diazepam; Drug | 1991 |
Controlled comparison of the efficacy and safety of four doses of suriclone, diazepam, and placebo in generalized anxiety disorder.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Double-Blind Method; Fema | 1991 |
Efficacy and safety of a putative anxiolytic agent: ipsapirone.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Double-Blind Method; Female; Humans; Male; | 1990 |
Short-acting versus long-acting benzodiazepines: discontinuation effects in panic disorders.
Topics: Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Drug Administration Schedule; Humans; | 1990 |
Etizolam in the treatment of generalized anxiety disorder: a double-blind study versus placebo.
Topics: Adult; Aged; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Depression; Diazepam; Double-Blind Met | 1990 |
Beta 2-adrenoceptor antagonism in anxiety.
Topics: Adrenergic beta-Antagonists; Adult; Anxiety Disorders; Diazepam; Double-Blind Method; Female; Humans | 1990 |
Controlled discontinuation of benzodiazepine treatment for patients with panic disorder.
Topics: Adult; Alprazolam; Anxiety Disorders; Diazepam; Double-Blind Method; Female; Half-Life; Humans; Male | 1991 |
Controlled comparison of pharmacological and psychological treatment of generalized anxiety disorder in primary care.
Topics: Adult; Anxiety Disorders; Cognitive Behavioral Therapy; Combined Modality Therapy; Diazepam; Female; | 1990 |
Decreased density of benzodiazepine receptors in lymphocytes of anxious patients: reversal after chronic diazepam treatment.
Topics: Anxiety Disorders; Diazepam; Down-Regulation; Humans; Long-Term Care; Lymphocytes; Neuropsychologica | 1990 |
High anxiety in children.
Topics: Adult; Age Factors; Anxiety Disorders; Child; Clinical Trials as Topic; Clonazepam; Diazepam; Humans | 1990 |
The Nottingham Study of Neurotic Disorder: relationship between personality status and symptoms.
Topics: Anxiety Disorders; Behavior Therapy; Clinical Trials as Topic; Cognitive Behavioral Therapy; Depress | 1990 |
Preference for diazepam in anxious adults.
Topics: Adult; Anxiety Disorders; Arousal; Attitude; Diazepam; Female; Humans; Male; Middle Aged; Personalit | 1990 |
Long-term therapeutic use of benzodiazepines. I. Effects of abrupt discontinuation.
Topics: Ambulatory Care; Anxiety Disorders; Benzodiazepines; Dependent Personality Disorder; Depressive Diso | 1990 |
Efficacy of combined antidepressant therapy in resistant neurotic disorder.
Topics: Adult; Amitriptyline; Anxiety Disorders; Clinical Trials as Topic; Depressive Disorder; Diazepam; Do | 1990 |
[Double-blind study of clobazam (Odipam) and diazepam in non-psychotic anxiety states].
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Benzodiazepinones; Cloba | 1989 |
Discrimination of mode of action of anxiolytics using an integrated computer data bank and Dynamic Brain Mapping (CNS effects of diazepam and lorazepam).
Topics: Adult; Anxiety Disorders; Brain; Brain Mapping; Central Nervous System; Diazepam; Double-Blind Metho | 1989 |
A pooled, double-blind comparison of the effects of buspirone, diazepam and placebo in women with chronic anxiety.
Topics: Adolescent; Adult; Aged; Anxiety Disorders; Buspirone; Clinical Trials as Topic; Diazepam; Double-Bl | 1989 |
Evaluation of buspirone as an antianxiety agent: buspirone and diazepam versus placebo.
Topics: Adult; Anxiety Disorders; Buspirone; Diazepam; Double-Blind Method; Female; Humans; Male; Multicente | 1989 |
Comparative assessment of efficacy and withdrawal symptoms after 6 and 12 weeks' treatment with diazepam or buspirone.
Topics: Adolescent; Adult; Anxiety Disorders; Buspirone; Clinical Trials as Topic; Diazepam; Double-Blind Me | 1989 |
Anxiety neurosis in general practice. A double-blind comparative study of diazepam and clovoxamine, a novel inhibitor of noradrenaline and serotonin reuptake.
Topics: Adolescent; Adult; Anxiety Disorders; Diazepam; Double-Blind Method; Female; Humans; Male; Middle Ag | 1989 |
Is diazepam an antidepressant?
Topics: Adult; Antidepressive Agents; Anxiety Disorders; Arousal; Benzamides; Depressive Disorder; Diazepam; | 1989 |
Etizolam in the treatment of generalized anxiety disorder associated with depressive symptoms.
Topics: Adult; Alprazolam; Anxiety Disorders; Consumer Behavior; Depression; Diazepam; Double-Blind Method; | 1989 |
Review of the side-effect profile of buspirone.
Topics: Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Buspirone; Clinical Trials as T | 1986 |
Effect of alprazolam and diazepam on anxiety and panic attacks in panic disorder: a controlled study.
Topics: Adult; Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Clinical Trials as Topic | 1986 |
Antianxiety properties of lormetazepam. A double-blind crossover trial versus diazepam.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Clinical Trials as Topic; Diazepam; | 1986 |
Suanzaorentang versus diazepam: a controlled double-blind study in anxiety.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Double-Blind Meth | 1986 |
Assessing the efficacy of antianxiety agents.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Buspirone; Clinical Trials as Topic; Diazepam; Double-Blind | 1987 |
A comparison of buspirone, diazepam, and placebo in patients with chronic anxiety states.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Buspirone; Chronic Disease; Clinical Trials as Topic; | 1987 |
Comparison of withdrawal of buspirone and diazepam: a placebo controlled study.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Buspirone; Diazepam; Female; Humans; Male; Middle Age | 1987 |
Suriclone and diazepam in the treatment of neurotic anxiety. A double-blind cross-over trial.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Double-Blind Meth | 1987 |
The Nottingham study of neurotic disorder: comparison of drug and psychological treatments.
Topics: Adult; Aged; Analysis of Variance; Anxiety Disorders; Behavior Therapy; Clinical Trials as Topic; Co | 1988 |
Placebo response in panic disorder.
Topics: Adult; Agoraphobia; Alprazolam; Anxiety Disorders; Clinical Trials as Topic; Dexamethasone; Diazepam | 1988 |
Multi-centre general practitioner comparative study of controlled-release ('Valrelease') and conventional ('Valium') forms of diazepam in patients suffering from anxiety.
Topics: Anxiety Disorders; Delayed-Action Preparations; Diazepam; Double-Blind Method; Family Practice; Huma | 1988 |
A clinical trial of buspirone and diazepam in the treatment of generalized anxiety disorder.
Topics: Adult; Anxiety Disorders; Buspirone; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female | 1987 |
Lack of preference for diazepam in anxious volunteers.
Topics: Adult; Amphetamine; Anxiety Disorders; Attitude to Health; Choice Behavior; Diazepam; Female; Humans | 1986 |
Six-week trial with diazepam: some clinical observations.
Topics: Adult; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Drug Administration Schedule; Educatio | 1985 |
Early treatment response in anxious outpatients treated with diazepam.
Topics: Adult; Ambulatory Care; Anxiety Disorders; Chronic Disease; Clinical Trials as Topic; Diazepam; Fema | 1985 |
[A new benzodiazepine screened in a parallel double-blind test].
Topics: Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Drug Evalua | 1974 |
A preliminary double-blind study with SB 5833 (camazepam), a new benzodiazepine derivative.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Carbamates; Clinical Trials as Topic; Depression; Dia | 1974 |
Clorazepate dipotassium, diazepam and placebo in chronic anxiety.
Topics: Adolescent; Adult; Aged; Anxiety Disorders; Benzazepines; Blood Pressure; Carboxylic Acids; Chronic | 1973 |
A multicenter investigation of lorazepam in anxiety neurosis.
Topics: Adult; Ambulatory Care; Anxiety Disorders; Benzazepines; Clinical Trials as Topic; Diazepam; Female; | 1973 |
A comparison of lorazepam, diazepam and placebo in the treatment of anxiety states.
Topics: Adolescent; Adult; Anxiety Disorders; Benzodiazepinones; Blood Pressure; Body Weight; Chlorobenzenes | 1974 |
A comparative trial of doxepin and diazepam in anxiety states.
Topics: Adult; Anxiety Disorders; Clinical Trials as Topic; Constipation; Diazepam; Dibenzoxepins; Fatigue; | 1972 |
A comparison of oxypertine and diazepam in anxiety neurosis seen in hospital out-patients.
Topics: Anxiety Disorders; Clinical Trials as Topic; Diazepam; Female; Humans; Indoles; Male; Outpatient Cli | 1972 |
Controlled trial of dipotassium clorazepate ("Tranxene") in anxiety.
Topics: Adolescent; Adult; Anxiety; Anxiety Disorders; Benzazepines; Carboxylic Acids; Clinical Trials as To | 1973 |
Orthogonal factors vs. interdependent variables as predictors of drug treatment response in anxious outpatients.
Topics: Ambulatory Care; Anxiety Disorders; Black or African American; Clinical Trials as Topic; Diazepam; E | 1973 |
A comparative double-blind trial of pimozide in stress-induced psychic and functional disorders.
Topics: Administration, Oral; Adult; Aged; Anxiety Disorders; Clinical Trials as Topic; Depression; Diazepam | 1972 |
Lorazepam in the treatment of anxiety.
Topics: Adolescent; Adult; Aged; Anxiety Disorders; Benzodiazepinones; Chlorobenzenes; Clinical Trials as To | 1972 |
Lorazepam and diazepam in severe neurotic illness.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anxiety Disorders; Clinical Trials as Topic; Diazepam | 1972 |
Comparison of lorazepam and diazepam in anxiety neurosis.
Topics: Administration, Oral; Adolescent; Adult; Anxiety Disorders; Behavior; Benzodiazepinones; Child; Chlo | 1973 |
A controlled double-blind comparison of lorazepam and diazepam in anxiety neurosis.
Topics: Administration, Oral; Adult; Anxiety Disorders; Benzodiazepinones; Central Nervous System; Chloroben | 1973 |
A double-blind controlled trial of lorazepam and diazepam in the treatment of anxiety.
Topics: Administration, Oral; Adult; Anxiety Disorders; Benzodiazepinones; Blood Chemical Analysis; Chlorobe | 1973 |
A comparison of lorazepam and diazepam in general practice.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anxiety Disorders; Benzodiazepinones; Chlorobenzenes; | 1973 |
Clinical experience with lorazepam in the treatment of neurotic patients.
Topics: Adult; Anxiety Disorders; Asthenia; Benzodiazepinones; Chlorobenzenes; Clinical Trials as Topic; Dia | 1973 |
Response to propranolol and diazepam in somatic and psychic anxiety.
Topics: Analysis of Variance; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Humans; Hypochondriasis | 1974 |
[Comparative clinical evaluation of lorazepam (author's transl)].
Topics: Adult; Anxiety Disorders; Benzodiazepinones; Chlorobenzenes; Clinical Trials as Topic; Diazepam; Dru | 1974 |
The effect of daily oral dosage of diazepam, plasma concentrations and metabolic clearance of diazepam and demethyldiazepam on various constituents of the acute clinical anxiety syndrome.
Topics: Adult; Anxiety; Anxiety Disorders; Autonomic Nervous System; Clinical Trials as Topic; Diazepam; Hum | 1974 |
The residual effects of N-desmethyldiazepam in patients.
Topics: Adolescent; Adult; Amobarbital; Anxiety Disorders; Child; Clinical Trials as Topic; Dealkylation; Di | 1974 |
The therapeutic effect of short-term oral diazepam treatment on acute clinical anxiety in a crisis centre.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Anxiety Disorders; Clinical Trials as Topic; Crisi | 1974 |
A comparison between diazepam and haloperidol in anxiety states.
Topics: Adult; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Drug Evaluation; Female; Haloperidol; | 1974 |
A comparison of thioridazine and diazepam in non-psychotic anxiety-depression: a pilot study.
Topics: Adjustment Disorders; Administration, Oral; Adult; Anxiety Disorders; Clinical Trials as Topic; Diaz | 1972 |
Clorazepate dipotassium in anxiety: a double-blind trial with diazepam controls.
Topics: Adjustment Disorders; Adult; Aged; Anxiety Disorders; Benzazepines; Carboxylic Acids; Clinical Trial | 1972 |
The use of self-rating scales in a single-patient multiple cross-over trial.
Topics: Adult; Anxiety Disorders; Chlordiazepoxide; Clinical Trials as Topic; Diazepam; Humans; Hydroxyzine; | 1968 |
Target symptoms: a promising improvement criterion in psychiatric drug research.
Topics: Adult; Anxiety Disorders; Carbamates; Clinical Trials as Topic; Diazepam; Emotions; Female; Humans; | 1968 |
The assessment of changes in anxiety in a drug trial: a comparison of methods.
Topics: Adolescent; Adult; Analysis of Variance; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Fema | 1968 |
[A double-blind study with doxepin in neurotic anxiety].
Topics: Anxiety Disorders; Clinical Trials as Topic; Diazepam; Dibenzoxepins; Humans; Placebos | 1969 |
Doxepin and diazepam in general practice and hospital clinic neurotic patients: A collaborative controlled study.
Topics: Adjustment Disorders; Analysis of Variance; Anxiety Disorders; Clinical Trials as Topic; Diazepam; D | 1969 |
Setting, patient, and doctor effects on drug response in neurotic patients. I. Differential attrition, dosage deviation, and side reaction responses to treatment.
Topics: Adult; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Family Practice; Female; Hospitals, Ps | 1970 |
Setting, patient, and doctor effects on drug response in neurotic patients. II. Differential improvement.
Topics: Adult; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Family Practice; Female; Hospitals, Ps | 1970 |
A technique in the evaluation of psychotropic medication based on a patient demand schedule: comparison of the efficacy of oxypertine, diazepam and placebo in anxiety.
Topics: Anxiety Disorders; Diazepam; Humans; Indoles; Personality Inventory; Piperazines; Placebos; Time Fac | 1971 |
[Treatment of anxiety neuroses in general practice using Lorazepam (Tavor)].
Topics: Adolescent; Adult; Anxiety Disorders; Ataxia; Diazepam; Electroencephalography; Evaluation Studies a | 1972 |
Reduction in symptomatology in ambulatory patients. The combined effects of a tranquilizer and psychotherapy.
Topics: Adult; Anxiety Disorders; Clinical Trials as Topic; Diazepam; Female; Humans; Male; Placebos; Psycho | 1966 |
Office evaluation of diazepam for psychoneurotic anxiety and depressive reactions.
Topics: Anxiety Disorders; Clinical Trials as Topic; Depression; Diazepam; Female; Humans; Male | 1966 |
Comparison of diazepam, chlordiazepoxide and amylobarbitone. (A multidose double blind crossover study).
Topics: Adult; Aged; Amobarbital; Anxiety Disorders; Chlordiazepoxide; Clinical Trials as Topic; Diazepam; F | 1967 |
152 other studies available for diazepam and Anxiety Neuroses
| Article | Year |
|---|---|
Imidazo[1,2-a]pyrimidines as functionally selective and orally bioavailable GABA(A)alpha2/alpha3 binding site agonists for the treatment of anxiety disorders.
Topics: Administration, Oral; Animals; Anxiety Disorders; Binding Sites; Biological Availability; Cell Line; | 2006 |
The anxiolytic effect of salicylic acid is mediated via the GABAergic system in the fear potentiated plus maze behavior in rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Behavior, Animal; Diazepam; Fear; GABAergi | 2022 |
Role of allopregnanolone biosynthesis in acute stress-induced anxiety-like behaviors in mice.
Topics: 5-alpha Reductase Inhibitors; Animals; Anxiety Disorders; Diazepam; Disease Models, Animal; Dose-Res | 2017 |
A Fatty Acids Mixture Reduces Anxiety-Like Behaviors in Infant Rats Mediated by GABA
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Fatty Acids; Fatty Acids, Monounsaturated | 2017 |
Quercetin mitigates anxiety-like behavior and normalizes hypothalamus-pituitary-adrenal axis function in a mouse model of mild traumatic brain injury.
Topics: Adrenocorticotropic Hormone; Animals; Anxiety; Anxiety Disorders; Brain Concussion; Corticosterone; | 2019 |
[Benzodiazepine dependence and the risk of depression and anxiety disorders: seniors' health study].
Topics: Aged; Aged, 80 and over; Anxiety Disorders; Benzodiazepines; Cohort Studies; Cross-Sectional Studies | 2014 |
NCS-1 deficiency causes anxiety and depressive-like behavior with impaired non-aversive memory in mice.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety Disorders; Avoidance Learnin | 2014 |
[Assessment of afobazole effects on diazepam withdrawal-induced anxiety in rats].
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Behavior, Animal; Benzimidazoles; Brain; Brain Chem | 2014 |
Anxiolytic-like effects of alverine citrate in experimental mouse models of anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Diazepam; Disease Models, Animal; Dose-Res | 2014 |
Minocycline does not evoke anxiolytic and antidepressant-like effects in C57BL/6 mice.
Topics: Animals; Anti-Anxiety Agents; Anti-Bacterial Agents; Antidepressive Agents; Anxiety Disorders; Depre | 2016 |
Investigation of diazepam efficacy on anxiety-like behavior in hemiparkinsonian rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Exploratory Behavior; Functional Laterali | 2016 |
Something old, something new: a successful case of meprobamate withdrawal.
Topics: Aged; Anxiety Disorders; Diazepam; Dose-Response Relationship, Drug; Humans; Inpatients; Male; Mepro | 2016 |
Selective corticotropin-releasing factor 1 receptor antagonist E2508 has potent antidepressant-like and anxiolytic-like properties in rodent models.
Topics: Acetylcholine; Administration, Oral; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Di | 2016 |
Topiramate reduces basal anxiety and relieves ethanol withdrawal-induced anxious behaviors in male rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Behavior, Animal; Diazepam; Disease Models | 2017 |
New patient asking for a benzodiazepine prescription.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Diazepam; Family Practice; Humans; M | 2008 |
Acute effects of bergamot oil on anxiety-related behaviour and corticosterone level in rats.
Topics: Administration, Inhalation; Animals; Anti-Anxiety Agents; Anxiety Disorders; Corticosterone; Diazepa | 2011 |
Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay.
Topics: Amidohydrolases; Animals; Anti-Anxiety Agents; Anxiety Disorders; Benzodioxoles; Cannabinoid Recepto | 2011 |
Pharmacological evaluation of the adequacy of marble burying as an animal model of compulsion and/or anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Behavior, Animal; Benzothiazoles; Carbolin | 2011 |
[Effect of GB-115 dipeptide on anxiety in rats with model benzodiazepine withdrawal syndrome].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Outbred Strains; Anti-Anxiety Agents; Anxiety Diso | 2011 |
GABAergic control of critical developmental periods for anxiety- and depression-related behavior in mice.
Topics: Age Factors; Analysis of Variance; Animals; Anxiety Disorders; Behavior, Animal; Depression; Diazepa | 2012 |
Posture and balance responses to a sensory challenge are related to anxiety in mice.
Topics: Animals; Anticonvulsants; Anxiety Disorders; Diazepam; Disease Models, Animal; Male; Mice; Mice, Inb | 2003 |
Paradoxical therapy in conversion reaction.
Topics: Adolescent; Adult; Anticonvulsants; Anxiety; Anxiety Disorders; Conversion Disorder; Diazepam; Femal | 2003 |
The clinical use of diazepam in anxiety states and depressions.
Topics: Anxiety; Anxiety Disorders; Depression; Depressive Disorder; Diazepam; Tranquilizing Agents | 1962 |
A double blind crossover comparison of diazepam (Valium, Ro5-2807) with chlordiazepoxide (Librium) in the treatment of neurotic anxiety.
Topics: Anxiety; Anxiety Disorders; Chlordiazepoxide; Cross-Over Studies; Diazepam; Double-Blind Method; Hum | 1962 |
[TRIAL CLINICAL EVALUATION OF A NEW TRANQUILIZER OF THE BENZODIAZEPINE GROUP].
Topics: Anxiety; Anxiety Disorders; Benzodiazepines; Chlordiazepoxide; Diazepam; Humans; Hypnotics and Sedat | 1963 |
DIAZEPAM IN TREATMENT OF EMOTIONAL DISORDERS.
Topics: Anxiety; Anxiety Disorders; Chlordiazepoxide; Diazepam; Geriatrics; Humans; Mood Disorders; Neurotic | 1963 |
TREATMENT OF ANXIETY NEUROSES AND PSYCHOSOMATIC SYNDROMES BY A NEW LIBRIUM-METABOLITE: VALIUM.
Topics: Anxiety; Anxiety Disorders; Asthenia; Chlordiazepoxide; Diazepam; Humans; Neurotic Disorders; Obsess | 1963 |
[CLINICAL EXPERIENCES WITH A NEW DRUG OF THE BENZODIAZEPINE SERIES: METHYLDIAZEPINONE].
Topics: Anxiety; Anxiety Disorders; Benzodiazepines; Brain Injuries; Depression; Diazepam; Humans; Mental Di | 1963 |
[CLINICAL EXPERIENCES IN TREATMENT WITH VALIUM].
Topics: Anxiety; Anxiety Disorders; Depression; Diazepam; Mental Disorders; Neurotic Disorders; Stress, Phys | 1963 |
[A NEW ANXIOLYTIC AGENT: RO 5-2807 OR DIAZEPAM].
Topics: Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Depression; Depressive Disorder; Diazepam; Humans; | 1963 |
[DIAZEPAM: A NEW ANXIOLYTIC AGENT].
Topics: Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Depression; Diazepam; Humans; Neurotic Disorders; O | 1964 |
ACONTROLLED STUDY OF DIAZEPAM IN PSYCHIATRIC OUTPATIENTS.
Topics: Adolescent; Anxiety; Anxiety Disorders; Depression; Diazepam; Geriatrics; Humans; Isocarboxazid; Neu | 1964 |
A NEW COMPOUND IN THE TREATMENT OF SEVERE ANXIETY STATES. REPORT ON THE USE OF DIAZEPAM.
Topics: Antidepressive Agents; Anxiety; Anxiety Disorders; Diazepam; Neurotic Disorders; Obsessive-Compulsiv | 1964 |
[OBSERVATIONS ON THE USE OF PHENYLPYRROLIDINOPENTANE AS AN ANTIASTHENIC AGENT IN TREATMENT WITH PSYCHOPHARMACOLOGICAL DRUGS].
Topics: Amitriptyline; Anxiety; Anxiety Disorders; Asthenia; Bipolar Disorder; Chemical and Drug Induced Liv | 1964 |
TREATMENT OF CHRONIC TENSION HEADACHE.
Topics: Amitriptyline; Amobarbital; Anxiety; Anxiety Disorders; Biomedical Research; Chlordiazepoxide; Diaze | 1964 |
[CLINICAL TRIALS WITH VALIUM IN PSYCHIATRIC PATHOLOGY].
Topics: Anxiety; Anxiety Disorders; Depression; Diazepam; Humans; Hypochondriasis; Hysteria; Mental Disorder | 1964 |
[EXPERIENCES IN RELATION TO THE PHARMACOLOGICAL TREATMENT OF FORMS OF ANXIETY NEUROSES].
Topics: Anxiety; Anxiety Disorders; Diazepam; Neurotic Disorders; Tranquilizing Agents | 1964 |
A CONTROLLED TRIAL WITH 'VALIUM' IN OBSESSIVE COMPULSIVE STATE.
Topics: Anxiety; Anxiety Disorders; Biomedical Research; Diazepam; Drug Therapy; Humans; Neurotic Disorders; | 1964 |
[CLINICAL TRIAL OF A NEW TRANQUILIZER, A BENZODIAZEPINE SERIES DERIVATIVE: RO 5-2807].
Topics: Anxiety; Anxiety Disorders; Autonomic Nervous System Diseases; Benzodiazepines; Combat Disorders; De | 1964 |
[CLINICAL EXPERIENCES WITH VALIUM ROCHE, A NEW BENZODIAZEPINE DERIVATIVE].
Topics: Antisocial Personality Disorder; Anxiety; Anxiety Disorders; Autonomic Nervous System Diseases; Benz | 1964 |
CLINICAL EVALUATION OF DIAZEPAM.
Topics: Adolescent; Anxiety; Anxiety Disorders; Biomedical Research; Chlordiazepoxide; Diazepam; Drug Therap | 1964 |
ROLE OF RELAXANTS IN TREATMENT OF TRAUMATIC MUSCULOSKELETAL DISORDERS: A DOUBLE-BLIND STUDY OF THREE AGENTS.
Topics: Anxiety; Anxiety Disorders; Biomedical Research; Carisoprodol; Chlormezanone; Diazepam; Double-Blind | 1964 |
[DIAZEPAM (VALIUM) IN NERVOUS ANXIETY AND TENSION. DOUBLE BLIND EXPERIMENT WITH PLACEBO CONTROL AND THE USE OF SEQUENTIAL ANALYSIS].
Topics: Anxiety; Anxiety Disorders; Biomedical Research; Diazepam; Double-Blind Method; Humans; Mental Disor | 1964 |
[INTEREST OF RO-2807 (VALIUM) IN TREATMENT OF ANXIETY STATES].
Topics: Anxiety; Anxiety Disorders; Diazepam; Drug Therapy; Humans; Neurotic Disorders | 1964 |
[CLINICAL BALANCE OF R.O. 2807 (VALIUM)].
Topics: Anxiety; Anxiety Disorders; Diazepam; Drug Therapy; Neurotic Disorders; Toxicology | 1964 |
[DIAZEPAM--A NEW ANXIETY-DECREASING AGENT. PRELIMINARY REPORT].
Topics: Anxiety; Anxiety Disorders; Chlordiazepoxide; Diazepam; Humans; Neurotic Disorders | 1964 |
COMPARISONS OF DIAZEPAM, CHLORPROMAZINE AND TRIFLUOPERAZINE IN A DOUBLE-BLIND CLINICAL INVESTIGATION.
Topics: Anxiety; Anxiety Disorders; Biomedical Research; Chlorpromazine; Depression; Depressive Disorder; De | 1964 |
DIAZEPAM AS AN ANTI-CONVULSANT AND ANTI-ANXIETY AGENT IN ECT.
Topics: Anti-Anxiety Agents; Anticonvulsants; Anxiety; Anxiety Disorders; Biomedical Research; Convulsants; | 1965 |
THE ROLE OF TRANQUILIZERS IN MEDICAL PRACTICE IN THE CONTROL OF ANXIETY. IMPORTANT AND RELEVANT ASPECTS OF TRANQUILIZER THERAPY.
Topics: Anxiety; Anxiety Disorders; Barbiturates; Biomedical Research; Chlordiazepoxide; Diazepam; Drug Ther | 1964 |
DOUBLE BLIND STUDY WITH DIAZEPAM, CHLORDIAZEPOXIDE AND PLACEBO IN THE TREATMENT OF PSYCHONEUROTIC ANXIETY.
Topics: Anxiety; Anxiety Disorders; Biomedical Research; Chlordiazepoxide; Diazepam; Double-Blind Method; Dr | 1964 |
DIAZEPAM AS AN ADJUVANT IN CLINICAL PSYCHOTHERAPY.
Topics: Anxiety; Anxiety Disorders; Depression; Diazepam; Drug Therapy; Neurotic Disorders; Obsessive-Compul | 1965 |
A DOUBLE-BLIND COMPARISON OF WY-3498, DIAZEPAM AND PLACEBO IN PSYCHIATRIC OUTPATIENTS.
Topics: Anxiety; Anxiety Disorders; Biomedical Research; Diazepam; Double-Blind Method; Drug Therapy; Humans | 1965 |
[RESTLESSNESS, COMPULSIONS, ANXIETY--STILL A THERAPEUTIC PROBLEM?].
Topics: Anxiety; Anxiety Disorders; Chlordiazepoxide; Compulsive Behavior; Diazepam; Humans; Neurotic Disord | 1964 |
[Experiences in policlinical treatment with librium analogue, Valium, with special reference to severe anxiety and compulsive neuroses].
Topics: Anxiety; Anxiety Disorders; Chlordiazepoxide; Compulsive Behavior; Diazepam; Humans; Neurotic Disord | 1962 |
Variability in the benzodiazepine response of serotonin 5-HT1A receptor null mice displaying anxiety-like phenotype: evidence for genetic modifiers in the 5-HT-mediated regulation of GABA(A) receptors.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Anxiety Disorders; Crosses, Genetic; Diazepam; Drug Resistan | 2004 |
BENZODIAZEPINES IN THE DIFFERENTIATION AND TREATMENT OF ANXIETIES.
Topics: Antidepressive Agents; Anxiety; Anxiety Disorders; Benzodiazepines; Chlordiazepoxide; Diazepam; Toxi | 1963 |
Cost-effectiveness of venlafaxine XL compared with diazepam in the treatment of generalised anxiety disorder in the United Kingdom.
Topics: Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Anxiety Disorders; Cost-Benefit Analy | 2005 |
Identification of glyoxalase-I as a protein marker in a mouse model of extremes in trait anxiety.
Topics: Analysis of Variance; Animals; Animals, Newborn; Anti-Anxiety Agents; Anxiety Disorders; Avoidance L | 2005 |
Social approach-avoidance behavior of a high-anxiety strain of rats: effects of benzodiazepine receptor ligands.
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Azepines; Carbolines; Chlordiazepoxide; Diazepam; G | 2006 |
Mouse strain differences in autonomic responses to stress.
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Autonomic Nervous System; Autonomic Nervous System | 2006 |
Pharmacological evaluation of the stress-induced social avoidance model of anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Brain; Buspirone; Chlordiazepoxide; Diazepam; Disea | 2006 |
Early response and 8-week treatment outcome in GAD.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Double-Blind Method; Female; Humans; Male; | 2006 |
Panic attack like episodes possibly associated with pramipexole therapy in Parkinson's disease.
Topics: Anxiety Disorders; Benzothiazoles; Carbidopa; Central Nervous System; Diazepam; Dopamine Agonists; D | 2007 |
Stimulation of the beta3-Adrenoceptor as a novel treatment strategy for anxiety and depressive disorders.
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Aggression; Animals; Anti-Anxiety Age | 2008 |
Chronic use of diazepam in primary healthcare centers: user profile and usage pattern.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Depressive Disorder; Diazepam; Drug Utilization; Female; Hum | 2007 |
GABA homeostasis contributes to the developmental programming of anxiety-related behavior.
Topics: Animals; Anxiety Disorders; Binding Sites; Brain; Brain Chemistry; Diazepam; Female; GABA Modulators | 2008 |
Pills for nerves.
Topics: Amitriptyline; Anxiety Disorders; Depressive Disorder; Diazepam; Drug Therapy, Combination; Humans; | 1980 |
Practical therapeutics. Anxiolytic drugs.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Benzodiazepinones; Clobazam; Diazepam; Huma | 1981 |
[Anxiety receptors: new pharmacological approach (author's transl)].
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Binding, Competitive; Brain; Chlordiazepoxide; Chlo | 1982 |
[Anxiolytics in man: studies on sleep and performance (author's transl)].
Topics: Anti-Anxiety Agents; Anxiety Disorders; Arousal; Attention; Benzodiazepines; Benzodiazepinones; Clob | 1982 |
Voice analysis of the effects of benzodiazepine tranquillizers.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Arousal; Benzodiazepines; Benzodiazepinones; Clobazam; Diaze | 1982 |
Long-term benzodiazepine administration blunts growth hormone response to diazepam.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Drug Tolerance; Growth Hormone; Humans; Lon | 1983 |
Value of serum diazepam and nordiazepam measurements in anxious patients.
Topics: Adult; Aged; Anxiety Disorders; Diazepam; Dose-Response Relationship, Drug; Female; Humans; Male; Mi | 1984 |
A benzodiazepine receptor-mediated model of anxiety. Studies in nonhuman primates and clinical implications.
Topics: Animals; Anxiety Disorders; Behavior, Animal; Blood Pressure; Carbolines; Clonidine; Diazepam; Dose- | 1984 |
Diazepam and desmethyldiazepam plasma concentrations in chronic anxious outpatients.
Topics: Adult; Anxiety Disorders; Chronic Disease; Diazepam; Female; Humans; Male; Middle Aged; Nordazepam | 1984 |
Withdrawal symptoms after long-term treatment with flurazepam.
Topics: Anxiety Disorders; Depressive Disorder; Diazepam; Flurazepam; Humans; Sleep Initiation and Maintenan | 1984 |
Serum dopamine-beta-hydroxylase activity in depression and anxiety.
Topics: Adult; Aged; Alprazolam; Anxiety; Anxiety Disorders; Benzodiazepines; Depression; Depressive Disorde | 1984 |
Chronic diazepam treatment in psychiatric outpatients.
Topics: Adult; Aged; Ambulatory Care; Anxiety Disorders; Chronic Disease; Diazepam; Humans; Male; Middle Age | 1982 |
Diazepam withdrawal.
Topics: Adult; Anxiety Disorders; Diazepam; Female; Humans; Substance Withdrawal Syndrome | 1983 |
Labelling and drug effects in the treatment of neurotic affective disorders: an experimental investigation.
Topics: Adolescent; Adult; Aged; Anxiety Disorders; Depressive Disorder; Diazepam; Double-Blind Method; Fema | 1983 |
A controlled trial of diazepam withdrawal in chronically anxious outpatients.
Topics: Adult; Aged; Anxiety Disorders; Chronic Disease; Diazepam; Dose-Response Relationship, Drug; Humans; | 1982 |
Current issues in the treatment of anxiety states and disorders.
Topics: Anxiety; Anxiety Disorders; Diazepam; Humans; Obsessive-Compulsive Disorder | 1982 |
The concept of somatic anxiety.
Topics: Anxiety Disorders; Diazepam; Drug Therapy, Combination; Humans; Propranolol; Psychophysiologic Disor | 1982 |
Withdrawal and pseudowithdrawal from diazepam therapy.
Topics: Adult; Anxiety Disorders; Attitude; Diazepam; Double-Blind Method; Humans; Male; Substance Withdrawa | 1981 |
Safety and efficacy of long-term diazepam therapy.
Topics: Adult; Anxiety Disorders; Diazepam; Double-Blind Method; Female; Humans; Male; Middle Aged; Prospect | 1980 |
Alcohol and benzodiazepines generate anxiety, panic and phobias.
Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Female; | 1995 |
Bioequivalence study for diazepam commercial tablets in psychiatric patients.
Topics: Administration, Oral; Adolescent; Adult; Anxiety Disorders; Biological Availability; Chromatography, | 1994 |
Personality and benzodiazepine sensitivity in anxious patients and control subjects.
Topics: Adult; Anxiety Disorders; Benzodiazepines; Diazepam; Female; Humans; Male; Models, Psychological; Pa | 1993 |
Serotonergic mechanisms involved in the exploratory behaviour of mice in a fully automated two-compartment black and white text box.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Anti-Anxiety Agents; A | 1995 |
[Benzodiazepine withdrawal syndrome in low dose dependency].
Topics: Anti-Anxiety Agents; Anxiety Disorders; Chlordiazepoxide; Depressive Disorder; Diazepam; Dose-Respon | 1996 |
125I-iomazenil binding shows stress- and/or diazepam-induced reductions in mouse brain: supporting data for 123I-iomazenil SPECT study of anxiety disorders.
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Autoradiography; Brain; Diazepam; Flumazenil; Iodin | 1997 |
Mechanism of triazolo-benzodiazepine and benzodiazepine action in anxiety and depression: behavioral studies with concomitant in vivo CA1 hippocampal norepinephrine and serotonin release detection in the behaving animal.
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Depressive Disorder; Diazepam; Exploratory Behavior | 1998 |
Gabapentin as a potential treatment for anxiety disorders.
Topics: Acetates; Adult; Alprazolam; Amines; Anticonvulsants; Anxiety Disorders; Cyclohexanecarboxylic Acids | 1998 |
Characterization of the behavioral profile of the non-peptide CRF receptor antagonist CP-154,526 in anxiety models in rodents. Comparison with diazepam and buspirone.
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Behavior, Animal; Buspirone; Diazepam; Male; Mice; | 1998 |
Benzodiazepine-induced chemotaxis is impaired in monocytes from patients with generalized anxiety disorder.
Topics: Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Benzodiazepinones; Chemotaxis, | 1999 |
A gene promotes anxiety in mice-and also in scientists.
Topics: Animals; Anxiety Disorders; Diazepam; Disease Models, Animal; Mice; Mice, Mutant Strains; Models, Ps | 1999 |
Akathisia masked by hypokinesia.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Anxiety Disorders; Clopenthixol; Diazepam; Fem | 2000 |
Effect of anxiolytics on blood sugar level in rabbits.
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Blood Glucose; Buspirone; Diabetes Complications; D | 2001 |
What are the issues surrounding long-term benzodiazepine treatment for generalized anxiety disorder.
Topics: Adult; Alprazolam; Anxiety Disorders; Benzodiazepines; Diazepam; Drug Administration Schedule; Femal | 1998 |
High-dose benzodiazepines in the treatment of severe neurotic anxiety.
Topics: Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Female; Flurazepam; Humans; Male; Oxa | 1978 |
Buspirone--a new antianxiety agent not chemically related to any presently marketed drugs [proceedings].
Topics: Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Humans; Psychiatric Status Rating Scales; Pyrimidi | 1979 |
Beta-adrenergic blocking drugs versus diazepam in the treatment of anxious-depressive syndrome.
Topics: Adrenergic beta-Antagonists; Anxiety Disorders; Depressive Disorder; Diazepam; Humans | 1977 |
Adverse reactions to marihuana use among college students.
Topics: Adult; Anxiety Disorders; Cannabis; Diazepam; Humans; Male | 1976 |
[Quantitative evaluation of neurovegetative systemic changes based on the degree of minute-rhythmic coupling and control quality in acute and chronic diazépam therapy of neuroses].
Topics: Adult; Anxiety Disorders; Autonomic Nervous System; Diazepam; Electrocardiography; Electrooculograph | 1975 |
Do benzodiazepines interfere with the action of electroconvulsive therapy?
Topics: Aged; Anxiety Disorders; Combined Modality Therapy; Depressive Disorder; Diazepam; Electroconvulsive | 1992 |
Cortisol levels in generalized anxiety disorder.
Topics: Adult; Analysis of Variance; Anxiety Disorders; Diazepam; Female; Humans; Hydrocortisone; Placebos; | 1991 |
Behavioral neurobiology of inverse agonist FG 7142 induced anxiety syndrome in rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Avoidance Learning; Carbolines; Diazepam; Explorato | 1990 |
Panic disorder: strategies for long-term treatment.
Topics: Adolescent; Adult; Alprazolam; Anxiety Disorders; Diazepam; Female; Humans; Panic | 1991 |
Benzodiazepine sensitivity in panic disorder.
Topics: Anxiety Disorders; Arousal; Diagnosis, Differential; Diazepam; Eye Movements; Humans; Panic; Researc | 1991 |
Reduced benzodiazepine sensitivity in panic disorder.
Topics: Adult; Anxiety Disorders; Brain Stem; Diazepam; Dose-Response Relationship, Drug; Eye Movements; Fea | 1990 |
The diagnosis and treatment of panic disorder in alcoholics: three cases.
Topics: Adult; Alcohol Drinking; Alcoholism; Anxiety Disorders; Clonazepam; Diazepam; Follow-Up Studies; Hum | 1990 |
Reduction of gastrointestinal symptoms following treatment for panic disorder.
Topics: Adult; Alprazolam; Anxiety Disorders; Colonic Diseases, Functional; Diazepam; Fear; Female; Gastroin | 1990 |
Increased serum total cholesterol to HDL-cholesterol ratio after imipramine.
Topics: Adult; Anxiety Disorders; Cholesterol; Cholesterol, HDL; Depressive Disorder; Diazepam; Fear; Female | 1990 |
Preliminary evidence of benzodiazepine subsensitivity in panic disorder.
Topics: Adult; Anxiety Disorders; Arousal; Blood Pressure; Diazepam; Epinephrine; Fear; Female; Heart Rate; | 1989 |
The relationship of panic disorder and its treatment outcome to 24-hour urinary MHPG levels.
Topics: Adolescent; Adult; Aged; Alprazolam; Anxiety Disorders; Diazepam; Double-Blind Method; Fear; Glycols | 1989 |
Sexual dysfunction associated with diazepam but not with clonazepam.
Topics: Adult; Anxiety Disorders; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Erectile Dysfuncti | 1989 |
Comparison of diazepam and buspirone.
Topics: Anxiety Disorders; Buspirone; Diazepam; Humans | 1989 |
Age-related multiple-dose pharmacokinetics and anxiolytic effects of delorazepam (chlordesmethyldiazepam).
Topics: Adult; Aged; Aging; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Diazepam; Female; Human | 1986 |
Biological markers in panic states: lactate-induced panic and mitral valve prolapse.
Topics: Adolescent; Adult; Aged; Agoraphobia; Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Creatinine | 1987 |
Impact of anxiety therapy on patients' quality of life.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Automobile Driving; Buspirone; Diazepam; Drug Interactions; | 1987 |
Seizures following triazolam withdrawal despite benzodiazepine treatment.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Chlordiazepoxide; Diazepam; Humans; Male; Middle Aged; Recep | 1987 |
Diazepam preference in subjects seeking treatment for anxiety.
Topics: Adult; Anxiety; Anxiety Disorders; Arousal; Confusion; Depression; Diazepam; Fatigue; Female; Humans | 1987 |
Delusional depression following benzodiazepine withdrawal.
Topics: Adult; Anxiety Disorders; Delusions; Depressive Disorder; Diazepam; Female; Humans; Lorazepam; Male; | 1988 |
[Clinical study of etizolam in patients with anxiety and insomnia].
Topics: Adult; Aged; Anxiety Disorders; Diazepam; Female; Humans; Male; Middle Aged; Psychiatric Status Rati | 1988 |
[Reaction to the sudden withdrawal of diazepam in patients with anxiety neurosis].
Topics: Anxiety Disorders; Diazepam; Gastrointestinal Diseases; Humans; Muscular Diseases; Substance Withdra | 1986 |
One-year follow-up of anxious patients treated with diazepam.
Topics: Adult; Anxiety Disorders; Diazepam; Female; Follow-Up Studies; Humans; Male; Psychiatric Status Rati | 1986 |
Emergency treatment of acute psychosis, agitation, and anxiety.
Topics: Anxiety Disorders; Diazepam; Droperidol; Emergencies; Haloperidol; Humans; Lorazepam; Panic; Propran | 1985 |
The concentrations of diazepam and its metabolites in the plasma after an acute and chronic administration.
Topics: Anxiety Disorders; Chromatography, Gas; Diazepam; Humans; Methylation; Microsomes, Liver; Oxazepam; | 1974 |
Proceedings: Isolation-induced timidity in mice as a measure of anxiolytic activity of drugs.
Topics: Animals; Anxiety Disorders; Barbiturates; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Diaze | 1974 |
Prescription of psychotropic drugs by general practitioners. 1. General.
Topics: Adjustment Disorders; Adolescent; Adult; Aged; Alcoholism; Antidepressive Agents; Anxiety Disorders; | 1973 |
Psychotropic drugs in use today. The role of diazepam in medical practice.
Topics: Anxiety Disorders; Chlordiazepoxide; Depression; Diazepam; Drug Interactions; Drug Utilization; Fami | 1973 |
Lorazepam in the treatment of severe anxiety and anxiety associated with psychotic conditions.
Topics: Adult; Aggression; Amitriptyline; Anxiety Disorders; Ataxia; Benzodiazepinones; Bipolar Disorder; Ch | 1973 |
[Treatment of psychosomatic gastrointestinal disorders in ambulatory patients].
Topics: Adjustment Disorders; Adult; Aged; Ambulatory Care; Anxiety Disorders; Diazepam; Drug Combinations; | 1973 |
Plasma level of diazepam as a therapeutic predictor in anxiety states.
Topics: Adult; Anxiety Disorders; Diazepam; Dose-Response Relationship, Drug; Fatigue; Female; Humans; Male; | 1974 |
Letter: Response to propranolol and diazepam in somatic and psychic anxiety.
Topics: Anxiety; Anxiety Disorders; Diazepam; Humans; Propranolol; Psychophysiologic Disorders | 1974 |
Chemotherapy in child psychiatry.
Topics: Amphetamine; Anxiety Disorders; Child; Child Psychiatry; Child, Preschool; Chlordiazepoxide; Diazepa | 1972 |
Treatment of anxiety.
Topics: Adolescent; Adult; Anxiety; Anxiety Disorders; Behavior Therapy; Chlorpromazine; Chronic Disease; Di | 1972 |
Initial psychopharmacological study of lorazepam (Wy 4036).
Topics: Adult; Anxiety; Anxiety Disorders; Benzazepines; Chlordiazepoxide; Diazepam; Female; Humans; Male; O | 1971 |
[Use and abuse of benzodiazepines].
Topics: Anxiety Disorders; Diazepam; Humans; Substance-Related Disorders | 1971 |
[Tranylcypromine, trifluoperazine, diazepam and amobarbital in anxiety and depressive states. Clinical experimentation].
Topics: Adjustment Disorders; Amobarbital; Anxiety Disorders; Diazepam; Evaluation Studies as Topic; Humans; | 1971 |
[Flurazepam in depressive anxiety syndromes].
Topics: Adjustment Disorders; Adult; Aged; Anxiety; Anxiety Disorders; Benzodiazepinones; Depression; Diazep | 1971 |
Interdisciplinary study of diazepam sedation for outpatient dentistry.
Topics: Adolescent; Adult; Amnesia; Anesthesia, Dental; Anesthesia, Intravenous; Anesthesia, Local; Anxiety | 1970 |
[Use of injectable medazepam (preliminar report)].
Topics: Adolescent; Adult; Anxiety Disorders; Diazepam; Female; Humans; Injections, Intramuscular; Injection | 1970 |
[Use and misuse of benzodiazepine derivatives].
Topics: Animals; Antidepressive Agents; Anxiety Disorders; Chlordiazepoxide; Diazepam; Humans; Substance-Rel | 1971 |
[On the use of Librium and Valium in general medicine, in adults].
Topics: Adolescent; Adult; Affective Symptoms; Aged; Anxiety; Anxiety Disorders; Chlordiazepoxide; Depressio | 1967 |
[On the parenteral use of 17-chloro-methyl-5-phenyl-3H-1,4-benzodiazepin-2(lH)-one in anxiety states].
Topics: Anxiety; Anxiety Disorders; Diazepam; Humans | 1967 |
The treatment of early anxiety, neurosis.
Topics: Adult; Amobarbital; Amphetamine; Anxiety Disorders; Chlordiazepoxide; Diazepam; Electroconvulsive Th | 1968 |
[The influence of the sequence in cross over trials].
Topics: Anxiety Disorders; Chlordiazepoxide; Diazepam; Hospitalization; Humans; Methylphenidate; Placebos | 1968 |
["Paradoxical" psychic effects of benzodiazepines].
Topics: Anxiety Disorders; Chlordiazepoxide; Diazepam; Humans; Oxazepam; Psychoses, Substance-Induced; Tranq | 1968 |
[Comparative studies on the action profile of some benzodiazepine derivatives].
Topics: Anticonvulsants; Anxiety Disorders; Benzazepines; Chlordiazepoxide; Diazepam; Epilepsy; Humans; Hypn | 1968 |
[The benzodiazepine derivatives in anxiety states].
Topics: Anxiety; Anxiety Disorders; Chlordiazepoxide; Diazepam; Humans | 1963 |
[Evaluation of clinical and outpatient administration of valium].
Topics: Adolescent; Adult; Aged; Anxiety Disorders; Diazepam; Female; Humans; Male; Middle Aged; Neurastheni | 1966 |