diazepam has been researched along with Angelman Syndrome in 2 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Angelman Syndrome: A syndrome characterized by multiple abnormalities, MENTAL RETARDATION, and movement disorders. Present usually are skull and other abnormalities, frequent infantile spasms (SPASMS, INFANTILE); easily provoked and prolonged paroxysms of laughter (hence happy); jerky puppetlike movements (hence puppet); continuous tongue protrusion; motor retardation; ATAXIA; MUSCLE HYPOTONIA; and a peculiar facies. It is associated with maternal deletions of chromosome 15q11-13 and other genetic abnormalities. (From Am J Med Genet 1998 Dec 4;80(4):385-90; Hum Mol Genet 1999 Jan;8(1):129-35)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oral diazepam was well-tolerated with no major side effects." | 5.48 | Diazepam for outpatient treatment of nonconvulsive status epilepticus in pediatric patients with Angelman syndrome. ( Chan, F; Grocott, O; Thibert, R; Tourjee, A; Worden, L, 2018) |
| "Oral diazepam was well-tolerated with no major side effects." | 1.48 | Diazepam for outpatient treatment of nonconvulsive status epilepticus in pediatric patients with Angelman syndrome. ( Chan, F; Grocott, O; Thibert, R; Tourjee, A; Worden, L, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Worden, L | 1 |
| Grocott, O | 1 |
| Tourjee, A | 1 |
| Chan, F | 1 |
| Thibert, R | 1 |
| Kuribayashi, R | 1 |
| Watabe, Y | 1 |
| Imataka, G | 1 |
| Yamanouchi, H | 1 |
2 other studies available for diazepam and Angelman Syndrome
| Article | Year |
|---|---|
Diazepam for outpatient treatment of nonconvulsive status epilepticus in pediatric patients with Angelman syndrome.
Topics: Ambulatory Care; Ambulatory Care Facilities; Angelman Syndrome; Anticonvulsants; Child; Child, Presc | 2018 |
[A successful single nocturnal use of diazepam to treat non-convulsive status epilepticus].
Topics: Angelman Syndrome; Anticonvulsants; Circadian Rhythm; Diazepam; Drug Administration Schedule; Electr | 2007 |