diazepam and Amblyopia, Developmental studies

diazepam and Amblyopia, Developmental

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Research Excerpts

Excerpt	Relevance	Reference
" We found that chronic administration of fluoxetine reinstates ocular dominance plasticity in adulthood and promotes the recovery of visual functions in adult amblyopic animals, as tested electrophysiologically and behaviorally."	1.35	The antidepressant fluoxetine restores plasticity in the adult visual cortex. ( Baroncelli, L; Castrén, E; De Pasquale, R; Maffei, L; Maya Vetencourt, JF; O'Leary, OF; Sale, A; Viegi, A, 2008)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (66.67)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (33.33)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

2 (66.67)

18.7374

1990's

0 (0.00)

18.2507

2000's

1 (33.33)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Maya Vetencourt, JF	1
Sale, A	1
Viegi, A	1
Baroncelli, L	1
De Pasquale, R	1
O'Leary, OF	1
Castrén, E	1
Maffei, L	1
Tsutsui, J	2
Nobuto, F	1
Watanabe, S	1
Sudo, A	1
Takaya, S	1

Studies

Maya Vetencourt, JF

Sale, A

Viegi, A

Baroncelli, L

De Pasquale, R

O'Leary, OF

Castrén, E

Maffei, L

Tsutsui, J

Nobuto, F

Watanabe, S

Sudo, A

Takaya, S

Clinical Trials (1)

Trial Overview

Trial	Phase	Enrollment	Study Type	Start Date	Status
FLOW Trial: Fluoxetine to Open the Critical Period Time Window to Improve Motor Recovery After Stroke[NCT03448159]	Phase 2	52 participants (Actual)	Interventional	2019-01-01	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial

Phase

Enrollment

Study Type

Start Date

Status

FLOW Trial: Fluoxetine to Open the Critical Period Time Window to Improve Motor Recovery After Stroke[NCT03448159]

Phase 2

52 participants (Actual)

Interventional

2019-01-01

Completed

[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

3 other studies available for diazepam and Amblyopia, Developmental

Article	Year
The antidepressant fluoxetine restores plasticity in the adult visual cortex. Science (New York, N.Y.), 2008, Apr-18, Volume: 320, Issue:5874 Topics: Amblyopia; Animals; Antidepressive Agents, Second-Generation; Brain-Derived Neurotrophic Factor; Dia	2008
[Treatment of nystagmic amblyopia with neuro-psychotropic drugs. II. Diazepam (cercine)]. Nihon ganka kiyo, 1966, Volume: 17, Issue:3 Topics: Adolescent; Adult; Amblyopia; Child; Diazepam; Electroencephalography; Humans; Nystagmus, Pathologic	1966
[Pharmacological orthoptics]. Ganka. Ophthalmology, 1967, Volume: 9, Issue:2 Topics: Adolescent; Adult; Amblyopia; Amobarbital; Bemegride; Child; Child, Preschool; Diazepam; Female; Hum	1967

Article

Year

The antidepressant fluoxetine restores plasticity in the adult visual cortex.

Science (New York, N.Y.), 2008, Apr-18, Volume: 320, Issue:5874

Topics: Amblyopia; Animals; Antidepressive Agents, Second-Generation; Brain-Derived Neurotrophic Factor; Dia

2008

[Treatment of nystagmic amblyopia with neuro-psychotropic drugs. II. Diazepam (cercine)].

Nihon ganka kiyo, 1966, Volume: 17, Issue:3

Topics: Adolescent; Adult; Amblyopia; Child; Diazepam; Electroencephalography; Humans; Nystagmus, Pathologic

1966

[Pharmacological orthoptics].

Ganka. Ophthalmology, 1967, Volume: 9, Issue:2

Topics: Adolescent; Adult; Amblyopia; Amobarbital; Bemegride; Child; Child, Preschool; Diazepam; Female; Hum

1967